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LAKSPARRCTAKVRRVLSRSVLILCWSLLGAAPAHADDSRLGWPLRPPPAVVRQFDAASPNWNPGHRGVD LAGRPGQPVYAAGSATVVFAGLLAGRPVVSLAHPGGLRTSYEPVVAQVRVGQPVSAPTVIGALAAGHPGC QAAACLHWGAMWGPASGANYVDPLGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKS PKQGVFRGAAQGGDIVARQPPGRWVCPSSAGGPIGWHRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2891 | - | - | 100% (249) | hypothetical protein Rv2891 |
| M. tuberculosis H37Rv | Rv0950c | - | 9e-07 | 32.56% (129) | hypothetical protein Rv0950c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2915 | - | 1e-148 | 100.00% (249) | hypothetical protein Mb2915 |
| M. gilvum PYR-GCK | Mflv_4134 | - | 1e-57 | 66.04% (159) | peptidase M23B |
| M. leprae Br4923 | MLBr_00154 | - | 1e-05 | 31.43% (140) | hypothetical protein MLBr_00154 |
| M. abscessus ATCC 19977 | MAB_3197 | - | 2e-50 | 60.87% (161) | hypothetical protein MAB_3197 |
| M. marinum M | MMAR_1818 | - | 3e-67 | 73.72% (156) | hypothetical protein MMAR_1818 |
| M. avium 104 | MAV_3745 | - | 3e-67 | 74.69% (162) | M23 peptidase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2518 | - | 3e-56 | 64.29% (168) | peptidase M23B |
| M. thermoresistible (build 8) | TH_0847 | - | 4e-29 | 69.62% (79) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4721 | - | 1e-06 | 34.29% (105) | hypothetical protein MUL_4721 |
| M. vanbaalenii PYR-1 | Mvan_2208 | - | 2e-62 | 68.71% (163) | peptidase M23B |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2891|M.tuberculosis_H37Rv --------------------------------------------------
Mb2915|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1818|M.marinum_M --------------------------------------------------
MAV_3745|M.avium_104 --------------------------------------------------
TH_0847|M.thermoresistible__bu --------------------------------------------------
Mflv_4134|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2208|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3197|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2518|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00154|M.leprae_Br4923 ---------MAAEAVRSFRNRWLNHQRNDVTEIIPVDGFDDFDDLYDLDF
MUL_4721|M.ulcerans_Agy99 MSQHRYARTAVVGNPRTSRDRWLQHHRNEVTEIIPLDGFD------ELEL
Rv2891|M.tuberculosis_H37Rv --------------------------------------------------
Mb2915|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1818|M.marinum_M --------------------------------------------------
MAV_3745|M.avium_104 --------------------------------------------------
TH_0847|M.thermoresistible__bu --------------------------------------------------
Mflv_4134|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2208|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3197|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2518|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00154|M.leprae_Br4923 AEIDELQFSDDDYNFCNETQVLLASEIDDLQDIDSLA-------------
MUL_4721|M.ulcerans_Agy99 ADLDDLDFGDPEFDTG--RQLLQAPELDDLDEIDNLIPAWLATPSPVLVG
Rv2891|M.tuberculosis_H37Rv -----------------------------------------------MAK
Mb2915|M.bovis_AF2122/97 -----------------------------------------------MAK
MMAR_1818|M.marinum_M --------------------------------------------------
MAV_3745|M.avium_104 --------------------------------------------------
TH_0847|M.thermoresistible__bu --------------------------------------------------
Mflv_4134|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2208|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3197|M.abscessus_ATCC_1997 -------------------MLATRGFATWPSPRIQRAGLSTAAGMTLSRT
MSMEG_2518|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00154|M.leprae_Br4923 --SEPLAASANVAP---NFTSAPRRPCQHRKQPTSATRGRLLISAMAAGA
MUL_4721|M.ulcerans_Agy99 ATSEALPEPSAAVPPAANVAPAPRRGGQHRKQSTSAVKGRLLIGSMAAGA
Rv2891|M.tuberculosis_H37Rv SPARRCTAKVRRVLSRSVLILCWSLLG-----------------------
Mb2915|M.bovis_AF2122/97 SPARRCTAKVRRVLSRSVLILCWSLLG-----------------------
MMAR_1818|M.marinum_M -----MTVAASWLAS---WLAAWSLLG-----------------------
MAV_3745|M.avium_104 -----MRWAA--------LMLVVGLVG-----------------------
TH_0847|M.thermoresistible__bu --------------------------------------------------
Mflv_4134|M.gilvum_PYR-GCK -----MRVLV--------LVATLVAIC-----------------------
Mvan_2208|M.vanbaalenii_PYR-1 -----MRILA--------SAIAVAVVA-----------------------
MAB_3197|M.abscessus_ATCC_1997 ALPGHYDVVRFRRLGCVPLILALAVAGSP---------------------
MSMEG_2518|M.smegmatis_MC2_155 -----MKWKVMR------IMAAVVCAGLF---------------------
MLBr_00154|M.leprae_Br4923 MATAAHTVISHDDIPKTETVLTANASALSGATVSDATQGVQVITVHPAAS
MUL_4721|M.ulcerans_Agy99 AAAAAHTVTHQSDVTSMDTVLTANASALIGGSDSNEARGVQVIAAQPATN
Rv2891|M.tuberculosis_H37Rv -------------AAPAHADD-SRLGWPLRPPPAVVRQFDAASPNWNPGH
Mb2915|M.bovis_AF2122/97 -------------AAPAHADD-SRLGWPLRPPPAVVRQFDAASPNWNPGH
MMAR_1818|M.marinum_M -------------AAAAHADD-TRLQWPLRPPAVVLRGFDAPTPNWRPGH
MAV_3745|M.avium_104 -------------AVPAAAGD-LRLEWPLRPPPVVVRAFDAPAQDWHPGH
TH_0847|M.thermoresistible__bu --------------------------------------------------
Mflv_4134|M.gilvum_PYR-GCK -------------TAPAEADD-GRLEWPMRPRPAVVRAFDAPAPNWQRGH
Mvan_2208|M.vanbaalenii_PYR-1 -------------AAPAAADD-VRLGWPLKPSPTVVRQFDAPAPNWQRGH
MAB_3197|M.abscessus_ATCC_1997 ------------MAATAPADTGDRFGWPLSPRPAVIRQFDNPQQRWNRGH
MSMEG_2518|M.smegmatis_MC2_155 ------------WAVPADAET-VRFRWPLDPRPAVTRAFDAPSPNWQRGH
MLBr_00154|M.leprae_Br4923 TAVHNEEHAKGTAFAHERAQREARLSQPLYVMPTKGIFTSNFGYRWGVLH
MUL_4721|M.ulcerans_Agy99 VEAHKAEFARGVAFAQERAQREARLQQPLYVMPTKGIFTSNFGYRWGVLH
Rv2891|M.tuberculosis_H37Rv RGVDLAGRPGQPVYAAGSATVVFAGLLAGR-PVVSLAHPGGLRTSYEPVV
Mb2915|M.bovis_AF2122/97 RGVDLAGRPGQPVYAAGSATVVFAGLLAGR-PVVSLAHPGGLRTSYEPVV
MMAR_1818|M.marinum_M RGVDLAGVPGEPIFAAGDATVVYAGTLADW-PVVSLAHPGGLRTSYQPVR
MAV_3745|M.avium_104 RGVDLAGTAGQPVYAAGAGTVVFAGLLAGR-PVVSVAHPGGLRTSYEPVR
TH_0847|M.thermoresistible__bu ------------VTEGTGVTKVFR-------PXX--XHAGGLRTSYEPVL
Mflv_4134|M.gilvum_PYR-GCK RGVDLGGAEGQVIQAAASGTVVFAGELAGR-PLISVAHPGGLRTTYEPVS
Mvan_2208|M.vanbaalenii_PYR-1 RGVDLAGADGQPVYAAAAGTVVFAGDLAGR-PLVSIAHPGGLRTTYEPVR
MAB_3197|M.abscessus_ATCC_1997 RGVDLAGGPDQAVVAAGPGVVVFAGVLAGR-PLVSIEHHGGLRTTYEPVT
MSMEG_2518|M.smegmatis_MC2_155 RGVDLAAGAHQPVYAAGPGTVVFAGELAGR-PVVSIAHPGGLRTTYEPVR
MLBr_00154|M.leprae_Br4923 AGIDLANAIGTPILAVSDGVVIDVGPTAGYGMWVKLRHADGTVTLYGHVN
MUL_4721|M.ulcerans_Agy99 AGIDLANSIGTPIYAVSDGLVIDAGPTAGYGMWVKIRHADGTVTLYGHVN
: : * .* * * *
Rv2891|M.tuberculosis_H37Rv AQVR-VGQPVSAPTVIGALAAGHPGCQAA----ACLHWGAMWGPASGANY
Mb2915|M.bovis_AF2122/97 AQVR-VGQPVSAPTVIGALAAGHPGCQAA----ACLHWGAMWGPASGANY
MMAR_1818|M.marinum_M PTVR-AGQHVTAGSAVGTLVAGHPGCPAK----ACLHWGAMWGPASDAHY
MAV_3745|M.avium_104 AVVR-VGQPVTAQTVLGELLPGHPGCRASPAGGACLHWGAMWGPASGARY
TH_0847|M.thermoresistible__bu PAVR-AGERVGAGTVLGAVQAGHAGCRAP----ACLHWGAMWGPAARADY
Mflv_4134|M.gilvum_PYR-GCK PVVR-RGQVVSTGTALGHLVAGHPGCAAA----ACLHWGAMWGPSSRADY
Mvan_2208|M.vanbaalenii_PYR-1 PAVR-RGQQVTAGTALGELATGHPNCAAP----ACLHWGAMWGPASRADY
MAB_3197|M.abscessus_ATCC_1997 PVVR-PGQRVDEGAVIGLLQRGHPGCAMT----ACLHWGALRGPASSAHY
MSMEG_2518|M.smegmatis_MC2_155 AHVR-VGRTVAAGQSIGTLDEGHSGCPVA----ACLHWGAMWGPASRADY
MLBr_00154|M.leprae_Br4923 TTLVNVGQYVVAGDQIATMGTRGNSTG------PHLHFEVLLS---GSER
MUL_4721|M.ulcerans_Agy99 TTLVNVGQRVMAGDHIATMGNRGFSTG------PHLHFEVLQG---GTER
. : *. * :. : . . **: .: . :
Rv2891|M.tuberculosis_H37Rv VDPLGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKS
Mb2915|M.bovis_AF2122/97 VDPLGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKS
MMAR_1818|M.marinum_M VDPLGLLKSTPIRLKPVTG-------------------------------
MAV_3745|M.avium_104 VDPLGLVASTPIRLKPLGG-------------------------------
TH_0847|M.thermoresistible__bu VDPLGLLAETPIRLKPVGGAGSGAS-------------------------
Mflv_4134|M.gilvum_PYR-GCK VDPTGLVVTVTVRLKPLR--------------------------------
Mvan_2208|M.vanbaalenii_PYR-1 VDPLGLLGTTAIRLKPLR--------------------------------
MAB_3197|M.abscessus_ATCC_1997 LNPLGLLAAIPLRLKPL---------------------------------
MSMEG_2518|M.smegmatis_MC2_155 VDPLGLLAA--VRLKPLQTGLQSAR-------------------------
MLBr_00154|M.leprae_Br4923 IDPVPWLAKRGIYVGNYTG-------------------------------
MUL_4721|M.ulcerans_Agy99 IDPVPWLAKRGLNVGNYAG-------------------------------
::* : : :
Rv2891|M.tuberculosis_H37Rv PKQGVFRGAAQGGDIVARQPPGRWVCPSSAGGPIGWHRQ
Mb2915|M.bovis_AF2122/97 PKQGVFRGAAQGGDIVARQPPGRWVCPSSAGGPIGWHRQ
MMAR_1818|M.marinum_M ---------------------------------------
MAV_3745|M.avium_104 ---------------------------------------
TH_0847|M.thermoresistible__bu ---------------------------------------
Mflv_4134|M.gilvum_PYR-GCK ---------------------------------------
Mvan_2208|M.vanbaalenii_PYR-1 ---------------------------------------
MAB_3197|M.abscessus_ATCC_1997 ---------------------------------------
MSMEG_2518|M.smegmatis_MC2_155 ---------------------------------------
MLBr_00154|M.leprae_Br4923 ---------------------------------------
MUL_4721|M.ulcerans_Agy99 ---------------------------------------