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M. tuberculosis H37Rv Rv2841c (nusA)

annotation: transcription elongation factor NusA
coordinates: 3148385 - 3149428
length: 347

NIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDRKTGVVRVIARETDEAGNLISE
WDDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRIGTETKA
SEGVIPAAEQVPGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEIADGSVEIVAVA
REAGHRSKIAVRSNVAGLNAKGACIGPMGQRVRNVMSELSGEKIDIIDYDDDPARFVANALSPAKVVSVS
VIDQTARAARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRGDAPPPPPGQPEPGVSRGMAHDR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2841cnusA-100% (347)transcription elongation factor NusA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2866cnusA0.0100.00% (347) transcription elongation factor NusA
M. gilvum PYR-GCKMflv_4041nusA1e-16286.81% (326) transcription elongation factor NusA
M. leprae Br4923MLBr_01558nusA1e-18091.93% (347) transcription elongation factor NusA
M. abscessus ATCC 19977MAB_3135cnusA1e-15784.19% (329) transcription elongation factor NusA
M. marinum MMMAR_1892nusA0.093.93% (346) N utilization substance protein a NusA
M. avium 104MAV_3695nusA0.092.02% (351) transcription elongation factor NusA
M. smegmatis MC2 155MSMEG_2625nusA1e-16484.10% (346) transcription elongation factor NusA
M. thermoresistible (build 8)TH_1292nusA1e-16684.10% (346) PROBABLE N UTILIZATION SUBSTANCE PROTEIN A NUSA
M. ulcerans Agy99MUL_2120nusA0.093.35% (346) transcription elongation factor NusA
M. vanbaalenii PYR-1Mvan_2312nusA1e-16086.96% (322) transcription elongation factor NusA

CLUSTAL 2.0.9 multiple sequence alignment


Rv2841c|M.tuberculosis_H37Rv        MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDR
Mb2866c|M.bovis_AF2122/97           MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDR
MAV_3695|M.avium_104                MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTEGHQNDARIEIDR
MMAR_1892|M.marinum_M               MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDR
MUL_2120|M.ulcerans_Agy99           MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDR
MLBr_01558|M.leprae_Br4923          MNIDMAALHAIEMDRGISVNELLDTIRSALLTAYRHTQGHQIDARIDIDR
TH_1292|M.thermoresistible__bu      MNIDMAALHAIEVDRGIPVDELLETIKSALLTAYRHTEGHEPDARIEIDR
Mflv_4041|M.gilvum_PYR-GCK          MNIDMAALHAIEADKGITVDVVVETIKSALLTAYRHTEGHEADAHIDIDR
Mvan_2312|M.vanbaalenii_PYR-1       ----MAALHAIEADKGISVDVVVDTIKSALLTAYRHTEGHEADAHIDIDR
MSMEG_2625|M.smegmatis_MC2_155      MNIDMAALHAIEADKGISVDVVVETIKSALLTAYRHTDGHEPDARIDIDR
MAB_3135c|M.abscessus_ATCC_199      MNIDPAAVNLMAADKGITVDEAIDIIKSALLTAYRHTDGHEPNARIEIDR
                                         **:: :  *:**.*:  :: *:**********:**: :*:*:***

Rv2841c|M.tuberculosis_H37Rv        KTGVVRVIARETDEAGNLISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
Mb2866c|M.bovis_AF2122/97           KTGVVRVIARETDEAGNLISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
MAV_3695|M.avium_104                KTGVVKVIARETDEDGNVISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
MMAR_1892|M.marinum_M               KTGVVRVMARETDDDGNVISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
MUL_2120|M.ulcerans_Agy99           KTGVVRVMARETDDDGNVISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
MLBr_01558|M.leprae_Br4923          KTGVVKVIAREVDDDGNVISEWDDTPEGFGRIAATTARQVMLQRFRDAEN
TH_1292|M.thermoresistible__bu      RTGAVQVIARQTDADGNVIHEWDDTPEGFGRIAATTARQVMLQRFRDAEN
Mflv_4041|M.gilvum_PYR-GCK          KTGVVKVMARQTDEDGNVLHEWDDTPEGFGRIAATTARQVILQRLRDAEN
Mvan_2312|M.vanbaalenii_PYR-1       KTGAVKVIARQTDEDGNVLHEWDDTPEGFGRIAATTARQVILQRLRDAEN
MSMEG_2625|M.smegmatis_MC2_155      KTGVVKVIARQTDADGNVLAEWDDTPEGFGRIAATTARQVILQRLRDAEN
MAB_3135c|M.abscessus_ATCC_199      KTGVVRVMARETDQDGNLITEWDATPEGFGRIAATTARQVFQQGVRDAEN
                                    :**.*:*:**:.*  **:: *** ****************: * .*****

Rv2841c|M.tuberculosis_H37Rv        ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRIGTETKASEGVIPAAE
Mb2866c|M.bovis_AF2122/97           ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRIGTETKASEGVIPAAE
MAV_3695|M.avium_104                ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGTETKASEGVIPAAE
MMAR_1892|M.marinum_M               ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGSETKASEGVIPSAE
MUL_2120|M.ulcerans_Agy99           ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGSETKASEGVIPSAE
MLBr_01558|M.leprae_Br4923          ERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGSETKASEGVIPAAE
TH_1292|M.thermoresistible__bu      ERIYGEFSAREGDIVAGVVQRDARENARGNVVVRLGTETKGSDGTIRPAE
Mflv_4041|M.gilvum_PYR-GCK          EKNYGEFSAREGDIVAGVIQRDARANARGLVVVRMGSETKGSEGVIPAAE
Mvan_2312|M.vanbaalenii_PYR-1       EKNYGEFSAREGDIVAGVIQRDARANARGLVVVRMGSETKGSEGVIPAAE
MSMEG_2625|M.smegmatis_MC2_155      EKVYGEFAAHEGDIVAGVIQRDARANARGLVVVRMGSETKGSEGVIPAAE
MAB_3135c|M.abscessus_ATCC_199      EHKFGEFSTREGEIVGGVIQRDARANARGLVVVRMGSETKGSEGVIPSAE
                                    *: :***:::**:**.**:***:* **** ****:*:***.*:*.* .**

Rv2841c|M.tuberculosis_H37Rv        QVPGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
Mb2866c|M.bovis_AF2122/97           QVPGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
MAV_3695|M.avium_104                QVPGESYEHGNRVRCYVIGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
MMAR_1892|M.marinum_M               QVPGESYEHGNRLRCYVVGVSRGSREPLITLSRTHPNLVRKLFSLEVPEI
MUL_2120|M.ulcerans_Agy99           QVPGESYEHGNRLRCYVVGVSRGSREPLITLSRTHPNLVRKLFSLEVPEI
MLBr_01558|M.leprae_Br4923          QVLGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
TH_1292|M.thermoresistible__bu      QVPGESYQHGDRLRCYVIGVTRGLREPRIELSRTHPNLVRKLFALEVPEI
Mflv_4041|M.gilvum_PYR-GCK          QVPGERYEHGDRLRCYVVGVARGAREPVITLSRTHPNLVRKLFSLEVPEI
Mvan_2312|M.vanbaalenii_PYR-1       QVPGERYEHGDRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
MSMEG_2625|M.smegmatis_MC2_155      QVPGERYEHGDRVRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEI
MAB_3135c|M.abscessus_ATCC_199      QVPGEEYHHGDRLRCYVVGVSRGAREPLITLSRTHPNLVRKLFSLEVPEI
                                    ** ** *.**:*:****:**:** *** * *************:******

Rv2841c|M.tuberculosis_H37Rv        ADGSVEIVAVAREAGHRSKIAVRSNVAGLNAKGACIGPMGQRVRNVMSEL
Mb2866c|M.bovis_AF2122/97           ADGSVEIVAVAREAGHRSKIAVRSNVAGLNAKGACIGPMGQRVRNVMSEL
MAV_3695|M.avium_104                ADGSVEIVAVAREAGHRSKIAVKSNLPGLNAKGACIGPMGQRVRNVMSEL
MMAR_1892|M.marinum_M               ADGSVEIVAVAREAGHRSKIAVRSNVPGLNAKGACIGPMGQRVRNVMSEL
MUL_2120|M.ulcerans_Agy99           ADGSVEIVAVAREAGHRSKIAVRSNVPGLNAKGACIGPMGQRVRNVMSEL
MLBr_01558|M.leprae_Br4923          ADGSVEIVSVAREAGHRSKIAVASRVPGLNAKGACIGPMGQRVRNVMSEL
TH_1292|M.thermoresistible__bu      AEGSVEIVAVAREAGHRSKIAVRSKVPGLNAKGACIGPMGQRVRNVMSEL
Mflv_4041|M.gilvum_PYR-GCK          ADGSVEIVAVAREAGHRSKIAVTSRAPGLNAKGACIGPMGQRVRNVMSEL
Mvan_2312|M.vanbaalenii_PYR-1       ADGSVEIVAVAREAGHRSKIAVATRAPGLNAKGACIGPMGQRVRNVMSEL
MSMEG_2625|M.smegmatis_MC2_155      ADGSVEIVAVAREAGHRSKIAVASRVPGLNAKGACIGPMGQRVRNVMSEL
MAB_3135c|M.abscessus_ATCC_199      SDGSVEIVAVAREAGHRSKIAVASKVSGLNAKGACIGPMGQRVRNVMSEL
                                    ::******:************* :. .***********************

Rv2841c|M.tuberculosis_H37Rv        SGEKIDIIDYDDDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLS
Mb2866c|M.bovis_AF2122/97           SGEKIDIIDYDDDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLS
MAV_3695|M.avium_104                SGEKIDIIDYDDDPARFVANALSPAKVVSVSIIDQAARAARVVVPDFQLS
MMAR_1892|M.marinum_M               SGEKIDIIDYDEDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLS
MUL_2120|M.ulcerans_Agy99           SGEKIDIIDYDEDPGRFVANALSPAKVVSVSVIDQTARAARVVVPDFQLS
MLBr_01558|M.leprae_Br4923          SGEKIDIIDYDEDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLS
TH_1292|M.thermoresistible__bu      SGEKIDIIDWDEDPAKFVANALSPAKVVSVSIIDEAARAARVVVPDFQLS
Mflv_4041|M.gilvum_PYR-GCK          SGEKIDIIDYDEDPARFVANALSPAKVVSVTVIDEAARAARVIVPDFQLS
Mvan_2312|M.vanbaalenii_PYR-1       SGEKIDIIDYDEDPARFVANALSPAKVVSVTVIDEAARAARVIVPDFQLS
MSMEG_2625|M.smegmatis_MC2_155      SGEKIDIIDYDEDPARFVANALSPAKVVSVSVIDEAGRAARVIVPDFQLS
MAB_3135c|M.abscessus_ATCC_199      SGEKIDIIDYDPDPARFVANALSPAKVVSVSVIDEAGKAARVIVPDFQLS
                                    *********:* **.:**************::**::.:****:*******

Rv2841c|M.tuberculosis_H37Rv        LAIGKEGQNARLAARLTGWRIDIRGDAPPPPPGQ----PEPGVSRGMAHD
Mb2866c|M.bovis_AF2122/97           LAIGKEGQNARLAARLTGWRIDIRGDAPPPPPGQ----PEPGVSRGMAHD
MAV_3695|M.avium_104                LAIGKEGQNARLAARLTGWRIDIRGDSPGGAGGHSESRPEHGATHGMVHD
MMAR_1892|M.marinum_M               LAIGKEGQNARLAARLTGWRIDIRGDSPEQSAEH----PERGASRGLAHD
MUL_2120|M.ulcerans_Agy99           LAIGKEGQNARLAARLTGWWIDIRGDSPEQSAEH----PERGASRGLAHD
MLBr_01558|M.leprae_Br4923          LAIGKEGQNARLAARLTGWRIDIRGDSPPCSAGQ----SEQNASHGMAHE
TH_1292|M.thermoresistible__bu      LAIGKEGQNARLAARLTGWRIDIRSDAAPGDTPE----PNPGAARGAVHE
Mflv_4041|M.gilvum_PYR-GCK          LAIGKEGQNARLAARLTGWRIDIRSDDADKNGGDGPGGHDRSASRPDAGR
Mvan_2312|M.vanbaalenii_PYR-1       LAIGKEGQNARLAARLTGWRIDIRSDDAAKEG----AVEER---------
MSMEG_2625|M.smegmatis_MC2_155      LAIGKEGQNARLAARLTGWRIDIRS-DAAPVG----DADARHGAAHDG--
MAB_3135c|M.abscessus_ATCC_199      LAIGKEGQNARLAARLTGWRIDIRS-DADPEN------------------
                                    ******************* ****.  .                      

Rv2841c|M.tuberculosis_H37Rv        R--
Mb2866c|M.bovis_AF2122/97           R--
MAV_3695|M.avium_104                R--
MMAR_1892|M.marinum_M               H--
MUL_2120|M.ulcerans_Agy99           H--
MLBr_01558|M.leprae_Br4923          R--
TH_1292|M.thermoresistible__bu      S--
Mflv_4041|M.gilvum_PYR-GCK          GVG
Mvan_2312|M.vanbaalenii_PYR-1       ---
MSMEG_2625|M.smegmatis_MC2_155      ---
MAB_3135c|M.abscessus_ATCC_199      ---