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M. tuberculosis H37Rv Rv2744c (35kd_ag)

annotation: CONSERVED 35 KDA ALANINE RICH PROTEIN
coordinates: 3057251 - 3058063
length: 270

ANPFVKAWKYLMALFSSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQVIGNQRQLEMRLNRQLADIEK
LQVNVRQALTLADQATAAGDAAKATEYNNAAEAFAAQLVTAEQSVEDLKTLHDQALSAAAQAKKAVERNA
MVLQQKIAERTKLLSQLEQAKMQEQVSASLRSMSELAAPGNTPSLDEVRDKIERRYANAIGSAELAESSV
QGRMLEVEQAGIQMAGHSRLEQIRASMRGEALPAGGTTATPRPATETSGGAIAEQPYGQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2744c35kd_ag-100% (270)CONSERVED 35 KDA ALANINE RICH PROTEIN
M. tuberculosis H37RvRv1278-1e-0422.02% (218) hypothetical protein Rv1278

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2765c35kd_ag1e-14599.63% (270) hypothetical protein Mb2765c
M. gilvum PYR-GCKMflv_3987-1e-12486.08% (273) phage shock protein A, PspA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3067c-1e-12486.30% (270) hypothetical protein MAB_3067c
M. marinum MMMAR_1971-1e-13090.44% (272) 35 kDa alanine rich protein
M. avium 104MAV_3635-1e-12988.04% (276) 35kd antigen
M. smegmatis MC2 155MSMEG_2695-1e-12488.76% (258) 35 kDa protein
M. thermoresistible (build 8)TH_132735kd_ag1e-12286.09% (266) CONSERVED 35 KDA ALANINE RICH PROTEIN
M. ulcerans Agy99MUL_3386-1e-12888.60% (272) 35 kDa alanine rich protein
M. vanbaalenii PYR-1Mvan_2398-1e-12587.18% (273) phage shock protein A, PspA

CLUSTAL 2.0.9 multiple sequence alignment


Rv2744c|M.tuberculosis_H37Rv        MANPFVKAWKYLMALFSSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQ
Mb2765c|M.bovis_AF2122/97           MANPFVKAWKYLMALFSSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQ
MMAR_1971|M.marinum_M               MANPFVKAWKYLMALFNSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQ
MUL_3386|M.ulcerans_Agy99           MANPFVKAWKYLMALFNSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQ
MAV_3635|M.avium_104                MANPFVKAWKYLMAKFNATIDERADPKVQIQQAIEEAQRTHQALTQQAAQ
Mflv_3987|M.gilvum_PYR-GCK          MANPFTKAWKYLMALFSSKVDEYADPKVQIQQAIEEAQRQHQALTQQAAQ
Mvan_2398|M.vanbaalenii_PYR-1       MANPFTKAWKYLMALFSSKVDEYADPKVQIQQAIEEAQRQHQALTQQAAQ
TH_1327|M.thermoresistible__bu      MANPFVKAWKYLMALFSSKVDEYADPKVQIQQAIEEAQRQHQALTQQAAQ
MSMEG_2695|M.smegmatis_MC2_155      MANPFVKAWKYLMALFSSKVDEYADPKVQIQQAIEDAQRQHQALTQQAAQ
MAB_3067c|M.abscessus_ATCC_199      MANPFVKAWKYLMALFNAKIDENADPKVQIQQAIEEAQRNHQALSQQAAS
                                    *****.******** *.:.:** ************:*** ****:****.

Rv2744c|M.tuberculosis_H37Rv        VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDAAKATEYNN
Mb2765c|M.bovis_AF2122/97           VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDAAKATEYNN
MMAR_1971|M.marinum_M               VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDAAKAVEYNN
MUL_3386|M.ulcerans_Agy99           VIGNQRQLEMRLNRQLADIEKLQVNARQALTLADQATAAGDAAKAVEYDN
MAV_3635|M.avium_104                VIGNQRQLEMRLNRQLADVEKLQVNVRQALTLADQATAAGDTAKATEYNN
Mflv_3987|M.gilvum_PYR-GCK          VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQAVAAGDTNKATEYNN
Mvan_2398|M.vanbaalenii_PYR-1       VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQAVAAGDAGKATEYNN
TH_1327|M.thermoresistible__bu      VIGNQRQLEMRLNRQLADVEKLQVNVRQALTLADQATAAGDTAKATEYTN
MSMEG_2695|M.smegmatis_MC2_155      VIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDVAKATEYNN
MAB_3067c|M.abscessus_ATCC_199      VIGNQRQLEMRLNRQLADVEKLQVNVRQALTLADQATTAGDTAKATEYNN
                                    ******************:******.**********.:***. **.** *

Rv2744c|M.tuberculosis_H37Rv        AAEAFAAQLVTAEQSVEDLKTLHDQALSAAAQAKKAVERNAMVLQQKIAE
Mb2765c|M.bovis_AF2122/97           AAEAFAAQLVTAEQSVEDLKTLHDQALSAAAQAKKAVERNAMVLQQKIAE
MMAR_1971|M.marinum_M               AAEAFAAQLVTAEQSVEDLKALHDQALNAAAQAKRAVEQNSMVLQQKIAE
MUL_3386|M.ulcerans_Agy99           AAEAFAAQLVTAEQSVEDLKALHDQALNAAAQAKRAVEQNSMVLQQKIAE
MAV_3635|M.avium_104                AAEAFAAQLVTAEQSVEDLKTLHDQALNAAAQAKKAVEQNAMVLQQKIAE
Mflv_3987|M.gilvum_PYR-GCK          AAEAFAAQLVTAEQSVEDLKGLHDQALQAAGQAKKAVEQNAMMLQQKVAE
Mvan_2398|M.vanbaalenii_PYR-1       AAEAFAAQLVTAEQSVEDLKALHDQALQAAGQAKKAVEQNAMVLQQKIAE
TH_1327|M.thermoresistible__bu      AAEAFAAQLVTAEQSVEDLKALHDQALNAAAQAKKAVEQNAMVLQQKIAE
MSMEG_2695|M.smegmatis_MC2_155      AAEAFAAQLVTAEQSVEDLKGLHDQALQAAGQAKKAVEQNAMMLQQKIAE
MAB_3067c|M.abscessus_ATCC_199      AAEAFAAQLVTAEQSVEDLKALHDQALAAAAQAKKAVEQNAMMLQQRIAE
                                    ******************** ****** **.***:***:*:*:***::**

Rv2744c|M.tuberculosis_H37Rv        RTKLLSQLEQAKMQEQVSASLRSMSELAAPGNTPSLDEVRDKIERRYANA
Mb2765c|M.bovis_AF2122/97           RTQLLSQLEQAKMQEQVSASLRSMSELAAPGNTPSLDEVRDKIERRYANA
MMAR_1971|M.marinum_M               RTKLLSQLEQAKMQEQVSSSLRSMSELAAPGNVPSLDEVRDKIERRYATA
MUL_3386|M.ulcerans_Agy99           RAKLLSQLEQAKMQEQVSSSLRSMSELAAPGNVPSLDEVRDKIERRYATA
MAV_3635|M.avium_104                RTKLLSQLEQAKMQEQVSASLQSMSELAAPGNVPSLDEVRDKIERRYANA
Mflv_3987|M.gilvum_PYR-GCK          RTKLLSQLEQAKMQEQVSSSLRSMSELAAPGNTPSLDEVRDKIERRYANA
Mvan_2398|M.vanbaalenii_PYR-1       RTKLLSQLEQAKMQEQVSASLRSMSEIAAPGSTPSLDEVRDKIERRYANA
TH_1327|M.thermoresistible__bu      RTKLLSQLEQAKMQEQVSASLRSMSELSAPGTTPSLDEVRQKIEQRYATA
MSMEG_2695|M.smegmatis_MC2_155      RTKLLSQLEQAKMQEQVSSSLRSMSELAAPGTTPSLDEVRQKIERRYANA
MAB_3067c|M.abscessus_ATCC_199      RTKLLSQLEQAKMQEQVSASLRSMSELAAPGNTPTLDEVRDKIERRYANA
                                    *::***************:**:****::***..*:*****:***:***.*

Rv2744c|M.tuberculosis_H37Rv        IGSAELAESSVQGRMLEVEQAGIQMAGHSRLEQIRASMRGEALPAGGTTA
Mb2765c|M.bovis_AF2122/97           IGSAELAESSVQGRMLEVEQAGIQMAGHSRLEQIRASMRGEALPAGGTTA
MMAR_1971|M.marinum_M               LGQAELAQSSVQGRMLEVQQAGVQMAGHSRLEQIRASMRGESLPAGGAAT
MUL_3386|M.ulcerans_Agy99           LGQAELAQSSVQGRMFEVQQAGVQMAGHSRLEQTRASMRGESLPAGGAAT
MAV_3635|M.avium_104                IGAAELAQGSVQGRMLEVEQAGVQMAGHSRLEQIRASMRGEALPTGGTPA
Mflv_3987|M.gilvum_PYR-GCK          IGSAELAQNSVQGRMLEVQQASVQMAGHSRLEQIRASMRGEQLPAGGNAA
Mvan_2398|M.vanbaalenii_PYR-1       MGSAELAQNSVQGRMMEVQQASVQMAGHSRLEQIRASMRGEQLPAGGATQ
TH_1327|M.thermoresistible__bu      MGEAELAQNSVQGRMLEVQQATVQMAGHARLEQIRAQMRGEPLPAGGAAS
MSMEG_2695|M.smegmatis_MC2_155      MGEAELAQNSVQGRMMEIQQASVQMAGHSRLEQIRASMRGEALPSGGATS
MAB_3067c|M.abscessus_ATCC_199      LGQAELAQNSVQGRMIEVEQASVQMAGHSRLEQIRASMKGEALPTGSTAT
                                    :* ****:.******:*::** :*****:**** **.*:** **:*. . 

Rv2744c|M.tuberculosis_H37Rv        TPRPATETSGG-------AIAEQ------PYGQ-
Mb2765c|M.bovis_AF2122/97           TPRPATETSGG-------AIAEQ------PYGQ-
MMAR_1971|M.marinum_M               PGATGATETGG-------AVAEK------PFGQQ
MUL_3386|M.ulcerans_Agy99           PGATGATETGG-------AVAEK------PFGQQ
MAV_3635|M.avium_104                AGGTQATPAPGQG--AGDAVSEK------PLGQ-
Mflv_3987|M.gilvum_PYR-GCK          --AAPNPTP------AAPAANPA---PENPLSQ-
Mvan_2398|M.vanbaalenii_PYR-1       --ATPAQSP------ATPAANPA---PENPLSQ-
TH_1327|M.thermoresistible__bu      GTAAPQATPTPSQETAKPAANPAK--PENPLSQ-
MSMEG_2695|M.smegmatis_MC2_155      TPATPSTQGTP----SDPATNQTPPNTENPLGQ-
MAB_3067c|M.abscessus_ATCC_199      --PAPATSP--------EQANPA-----NPLGQQ
                                       .                         * .*