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AVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRRRRRALRWGLVFTAGCLLWGLVTALL AAWGWFTSLLVITGTIAVTQAIPATLLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERG FFSLLGVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRSYLVPTINAFTAQLST GVRQYNEMVTAAAQLVSSANGAGGAGPGQQRYREELAGATDRLVAWAQAFDELGGLPRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2743c | - | - | 100% (270) | POSSIBLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2764c | - | 1e-150 | 100.00% (270) | hypothetical protein Mb2764c |
M. gilvum PYR-GCK | Mflv_3986 | - | 6e-78 | 58.74% (269) | putative membrane alanine rich protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3066c | - | 2e-64 | 51.74% (259) | hypothetical protein MAB_3066c |
M. marinum M | MMAR_1972 | - | 1e-109 | 74.91% (271) | hypothetical protein MMAR_1972 |
M. avium 104 | MAV_3634 | - | 1e-111 | 76.78% (267) | hypothetical protein MAV_3634 |
M. smegmatis MC2 155 | MSMEG_2696 | - | 1e-89 | 63.90% (277) | putative membrane alanine rich protein |
M. thermoresistible (build 8) | TH_0331 | - | 3e-29 | 69.79% (96) | POSSIBLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN |
M. ulcerans Agy99 | MUL_3385 | - | 5e-96 | 73.47% (245) | hypothetical protein MUL_3385 |
M. vanbaalenii PYR-1 | Mvan_2399 | - | 4e-81 | 59.48% (269) | putative membrane alanine rich protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3986|M.gilvum_PYR-GCK ---MVSTRTGRPDAWRSMAQRGIDTAAEWSGLVADRLSAAADPRAKLLRK Mvan_2399|M.vanbaalenii_PYR-1 ----MSTRTGRPEAWRSLAQRGIDTAADWSDMVAEKLHAAADPRAKLLRK TH_0331|M.thermoresistible__bu -------------------------------------------------- MSMEG_2696|M.smegmatis_MC2_155 ----MTTKTGRPEAWRSLLQRGIDTAAEVSGAVAEKLNAAADPRAKLLRK Rv2743c|M.tuberculosis_H37Rv ----MAVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRR Mb2764c|M.bovis_AF2122/97 ----MAVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRR MAV_3634|M.avium_104 ----MAVNATQPGPWRALLQRGVAAAADLSDLVARKISAATDPRARLLRR MMAR_1972|M.marinum_M ----MAVKSAQRGQRRALLQRGLDFVGDLSDFAARKISAATDPRARQLRR MUL_3385|M.ulcerans_Agy99 ----MAVKSAQRGQRRALLQRGLDFVGDLSDFAARKISAATDPRARQLRR MAB_3066c|M.abscessus_ATCC_199 MTPQPPRRAAVHGGWEQLLRRLATNVNDLGEELAARMRAMSDKREKLLRK Mflv_3986|M.gilvum_PYR-GCK RRRALRLGVFLTVSAVFWVAMTALVAVWDTPVWALFIPSPIAVGAAFLAT Mvan_2399|M.vanbaalenii_PYR-1 RRWALRLGVFFTLSTVLWVGVTALLASWSTPVWALFIPAPIAVGAGFLAT TH_0331|M.thermoresistible__bu -------------------------------------------------- MSMEG_2696|M.smegmatis_MC2_155 RRWALRFAVFFTFATGFWVFVTAVLAAWTTPVWVLIITGAIAAGAAFPAT Rv2743c|M.tuberculosis_H37Rv RRRALRWGLVFTAGCLLWGLVTALLAAWGWFTSLLVITGTIAVTQAIPAT Mb2764c|M.bovis_AF2122/97 RRRALRWGLVFTAGCLLWGLVTALLAAWGWFTSLLVITGTIAVTQAIPAT MAV_3634|M.avium_104 RRRALRWGLIFTAGCAFWAVLTIVLAAWGWFALLLEITGAVAVVMAIPAT MMAR_1972|M.marinum_M RRRALRWALIFSAGCVFWAAVTAVLAAWGWFALLLQITGAIAVVQVIPAT MUL_3385|M.ulcerans_Agy99 RRRALRWALIFSAGCVFWAAVTAVLAAWGWFALLLQITGAIAVVQVIPAT MAB_3066c|M.abscessus_ATCC_199 RLRAKRWSIRWALACVAGLLVTTVLATTGAPPWLLIIPALLTAGCAIPAT Mflv_3986|M.gilvum_PYR-GCK LAFLRYRWLRGEPLPPQR--ITRHLPPWGSAARQPMAALTTSERGLFSLL Mvan_2399|M.vanbaalenii_PYR-1 LAFLRYRWLRGEPLPPQRSRAARRLPPLGSAARQPMASLAASERGLFSLL TH_0331|M.thermoresistible__bu -------------------------------------------------- MSMEG_2696|M.smegmatis_MC2_155 LAWLRYRWLRRTPLPVQRPTVGRRLPPWGSAARQPMSALLASERGMFSLL Rv2743c|M.tuberculosis_H37Rv LLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERGFFSLL Mb2764c|M.bovis_AF2122/97 LLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERGFFSLL MAV_3634|M.avium_104 LLLLRYRWLRAEPLPAPRPATVRRLPPPGSAARPAMYALGASERGFASLL MMAR_1972|M.marinum_M LLFFRYYWLRSEPLPSQRPTTTRRLPPMGSAARPAMAALGASERGFFSLL MUL_3385|M.ulcerans_Agy99 LLFFRYYWLRSEPLPSQRPTTTRRLPPMGSAARPAMAAVGASERGFFSLL MAB_3066c|M.abscessus_ATCC_199 YLLVRYRYLKAEPLPPPRPGVERRLPPYGSSARPPMAALDAAERSLFSLL Mflv_3986|M.gilvum_PYR-GCK GIMERGQLLPAGELLELRVAAEQTAATMVATSAEVVSMEKAVKSSPQSRA Mvan_2399|M.vanbaalenii_PYR-1 GVMERGQLLPAGELLELRVAAEQTAATMAATATEVVSMEKAARSAPQSRA TH_0331|M.thermoresistible__bu ---------------------------MAATAGEVVSMERALRAAPQSRG MSMEG_2696|M.smegmatis_MC2_155 GVMERGRMLPPEELHELTTVANQAARTMMATAAEVVSMERAAGNAPQSRP Rv2743c|M.tuberculosis_H37Rv GVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRS Mb2764c|M.bovis_AF2122/97 GVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRS MAV_3634|M.avium_104 AVLERGAMLPAAEIRDLTAAAGRTSAAMASTAAQVVSMERAAQAGEESRS MMAR_1972|M.marinum_M GVMERGALVPAAEIQDLTDAANHSAAAMAATAAQVVSMERAAQYSESSRG MUL_3385|M.ulcerans_Agy99 GVMERGALVPAAEIQDLTDAANHSAAAMAATAAQVVSMERAAQYSESSRG MAB_3066c|M.abscessus_ATCC_199 GVVERGSMIPESEGRQVLSAANRAAYVMAATAKEVVSMERAAAETPHTRE * :*: :*****:* :* Mflv_3986|M.gilvum_PYR-GCK YLTPTIAAFTAQLDQGARQYNEMVGAAAQLVSAAN---SGTLS---SSPM Mvan_2399|M.vanbaalenii_PYR-1 YLAPTITAYTTQLDRGARQYNEMVSAAAQLVSAAN---SGPMS---RSPM TH_0331|M.thermoresistible__bu HLEPTIHAFTRQLDHGVRQYNEMVTAAAQLVSAAN---TGQMS---SSPM MSMEG_2696|M.smegmatis_MC2_155 HLVPTINAFAAQLNQGVRQYNEMVTAAAQLVSSVNGGANGQMPGGPAAPL Rv2743c|M.tuberculosis_H37Rv YLVPTINAFTAQLSTGVRQYNEMVTAAAQLVSSAN----GAGG---AGPG Mb2764c|M.bovis_AF2122/97 YLVPTINAFTAQLSTGVRQYNEMVTAAAQLVSSAN----GAGG---AGPG MAV_3634|M.avium_104 YLAPTINAFTAQLSAGVRQYNEMVTAAARLVSAAN----GDG-----STA MMAR_1972|M.marinum_M QLVPTINAFTAQLGAGVRQYNEMVTAAAQLVSSAN----GATV---AEAV MUL_3385|M.ulcerans_Agy99 QLVPTINAFTAQLGAGVRQYNEMVTAAAQLVSSAN----GATV---AEAV MAB_3066c|M.abscessus_ATCC_199 YLQPTIKAFTAQLDTGVRQYNELVTAAAQLVSAGN---GGAVV---ASPM * *** *:: **. *.*****:* ***:***: * * . Mflv_3986|M.gilvum_PYR-GCK SARRYRDELGM-ATDRLKGWAQAFDELG---------------RLRGA-- Mvan_2399|M.vanbaalenii_PYR-1 TQRRYRDELGM-ATDRLTGWAQAFDELG---------------RLKQA-- TH_0331|M.thermoresistible__bu SQRRYRDELTG-ATDRLVGWAQAFDELG---------------RLRSA-- MSMEG_2696|M.smegmatis_MC2_155 SQQRYRSELTG-ATDRLTGWAQAFDELG---------------GLRRA-- Rv2743c|M.tuberculosis_H37Rv QQ-RYREELAG-ATDRLVAWAQAFDELG---------------GLPRR-- Mb2764c|M.bovis_AF2122/97 QQ-RYREELAG-ATDRLVAWAQAFDELG---------------GLPRR-- MAV_3634|M.avium_104 SQ-HYRAELVG-ATDRLNGWAQAFDELG---------------GLRGAG- MMAR_1972|M.marinum_M SQQRYRHELVG-ATDRLAGWAQAFDELG---------------GLPRR-- MUL_3385|M.ulcerans_Agy99 SQQRYRPNWSELPIARPAGRRPSTNWVGYRAARCAPTCVPSALGSPRRPP MAB_3066c|M.abscessus_ATCC_199 SRGALFDDLVS-ATDRLTGWAGALDELG---------------QLSG--- : . * . : : :* Mflv_3986|M.gilvum_PYR-GCK ------------------ Mvan_2399|M.vanbaalenii_PYR-1 ------------------ TH_0331|M.thermoresistible__bu ------------------ MSMEG_2696|M.smegmatis_MC2_155 ------------------ Rv2743c|M.tuberculosis_H37Rv ------------------ Mb2764c|M.bovis_AF2122/97 ------------------ MAV_3634|M.avium_104 ------------------ MMAR_1972|M.marinum_M ------------------ MUL_3385|M.ulcerans_Agy99 RAAMPWSCRRNRSSRATA MAB_3066c|M.abscessus_ATCC_199 ------------------