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M. tuberculosis H37Rv Rv2743c (-)

annotation: POSSIBLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN
coordinates: 3056420 - 3057232
length: 270

AVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRRRRRALRWGLVFTAGCLLWGLVTALL
AAWGWFTSLLVITGTIAVTQAIPATLLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERG
FFSLLGVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRSYLVPTINAFTAQLST
GVRQYNEMVTAAAQLVSSANGAGGAGPGQQRYREELAGATDRLVAWAQAFDELGGLPRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2743c--100% (270)POSSIBLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2764c-1e-150100.00% (270) hypothetical protein Mb2764c
M. gilvum PYR-GCKMflv_3986-6e-7858.74% (269) putative membrane alanine rich protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3066c-2e-6451.74% (259) hypothetical protein MAB_3066c
M. marinum MMMAR_1972-1e-10974.91% (271) hypothetical protein MMAR_1972
M. avium 104MAV_3634-1e-11176.78% (267) hypothetical protein MAV_3634
M. smegmatis MC2 155MSMEG_2696-1e-8963.90% (277) putative membrane alanine rich protein
M. thermoresistible (build 8)TH_0331-3e-2969.79% (96) POSSIBLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN
M. ulcerans Agy99MUL_3385-5e-9673.47% (245) hypothetical protein MUL_3385
M. vanbaalenii PYR-1Mvan_2399-4e-8159.48% (269) putative membrane alanine rich protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3986|M.gilvum_PYR-GCK          ---MVSTRTGRPDAWRSMAQRGIDTAAEWSGLVADRLSAAADPRAKLLRK
Mvan_2399|M.vanbaalenii_PYR-1       ----MSTRTGRPEAWRSLAQRGIDTAADWSDMVAEKLHAAADPRAKLLRK
TH_0331|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2696|M.smegmatis_MC2_155      ----MTTKTGRPEAWRSLLQRGIDTAAEVSGAVAEKLNAAADPRAKLLRK
Rv2743c|M.tuberculosis_H37Rv        ----MAVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRR
Mb2764c|M.bovis_AF2122/97           ----MAVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRR
MAV_3634|M.avium_104                ----MAVNATQPGPWRALLQRGVAAAADLSDLVARKISAATDPRARLLRR
MMAR_1972|M.marinum_M               ----MAVKSAQRGQRRALLQRGLDFVGDLSDFAARKISAATDPRARQLRR
MUL_3385|M.ulcerans_Agy99           ----MAVKSAQRGQRRALLQRGLDFVGDLSDFAARKISAATDPRARQLRR
MAB_3066c|M.abscessus_ATCC_199      MTPQPPRRAAVHGGWEQLLRRLATNVNDLGEELAARMRAMSDKREKLLRK
                                                                                      

Mflv_3986|M.gilvum_PYR-GCK          RRRALRLGVFLTVSAVFWVAMTALVAVWDTPVWALFIPSPIAVGAAFLAT
Mvan_2399|M.vanbaalenii_PYR-1       RRWALRLGVFFTLSTVLWVGVTALLASWSTPVWALFIPAPIAVGAGFLAT
TH_0331|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2696|M.smegmatis_MC2_155      RRWALRFAVFFTFATGFWVFVTAVLAAWTTPVWVLIITGAIAAGAAFPAT
Rv2743c|M.tuberculosis_H37Rv        RRRALRWGLVFTAGCLLWGLVTALLAAWGWFTSLLVITGTIAVTQAIPAT
Mb2764c|M.bovis_AF2122/97           RRRALRWGLVFTAGCLLWGLVTALLAAWGWFTSLLVITGTIAVTQAIPAT
MAV_3634|M.avium_104                RRRALRWGLIFTAGCAFWAVLTIVLAAWGWFALLLEITGAVAVVMAIPAT
MMAR_1972|M.marinum_M               RRRALRWALIFSAGCVFWAAVTAVLAAWGWFALLLQITGAIAVVQVIPAT
MUL_3385|M.ulcerans_Agy99           RRRALRWALIFSAGCVFWAAVTAVLAAWGWFALLLQITGAIAVVQVIPAT
MAB_3066c|M.abscessus_ATCC_199      RLRAKRWSIRWALACVAGLLVTTVLATTGAPPWLLIIPALLTAGCAIPAT
                                                                                      

Mflv_3986|M.gilvum_PYR-GCK          LAFLRYRWLRGEPLPPQR--ITRHLPPWGSAARQPMAALTTSERGLFSLL
Mvan_2399|M.vanbaalenii_PYR-1       LAFLRYRWLRGEPLPPQRSRAARRLPPLGSAARQPMASLAASERGLFSLL
TH_0331|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2696|M.smegmatis_MC2_155      LAWLRYRWLRRTPLPVQRPTVGRRLPPWGSAARQPMSALLASERGMFSLL
Rv2743c|M.tuberculosis_H37Rv        LLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERGFFSLL
Mb2764c|M.bovis_AF2122/97           LLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERGFFSLL
MAV_3634|M.avium_104                LLLLRYRWLRAEPLPAPRPATVRRLPPPGSAARPAMYALGASERGFASLL
MMAR_1972|M.marinum_M               LLFFRYYWLRSEPLPSQRPTTTRRLPPMGSAARPAMAALGASERGFFSLL
MUL_3385|M.ulcerans_Agy99           LLFFRYYWLRSEPLPSQRPTTTRRLPPMGSAARPAMAAVGASERGFFSLL
MAB_3066c|M.abscessus_ATCC_199      YLLVRYRYLKAEPLPPPRPGVERRLPPYGSSARPPMAALDAAERSLFSLL
                                                                                      

Mflv_3986|M.gilvum_PYR-GCK          GIMERGQLLPAGELLELRVAAEQTAATMVATSAEVVSMEKAVKSSPQSRA
Mvan_2399|M.vanbaalenii_PYR-1       GVMERGQLLPAGELLELRVAAEQTAATMAATATEVVSMEKAARSAPQSRA
TH_0331|M.thermoresistible__bu      ---------------------------MAATAGEVVSMERALRAAPQSRG
MSMEG_2696|M.smegmatis_MC2_155      GVMERGRMLPPEELHELTTVANQAARTMMATAAEVVSMERAAGNAPQSRP
Rv2743c|M.tuberculosis_H37Rv        GVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRS
Mb2764c|M.bovis_AF2122/97           GVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRS
MAV_3634|M.avium_104                AVLERGAMLPAAEIRDLTAAAGRTSAAMASTAAQVVSMERAAQAGEESRS
MMAR_1972|M.marinum_M               GVMERGALVPAAEIQDLTDAANHSAAAMAATAAQVVSMERAAQYSESSRG
MUL_3385|M.ulcerans_Agy99           GVMERGALVPAAEIQDLTDAANHSAAAMAATAAQVVSMERAAQYSESSRG
MAB_3066c|M.abscessus_ATCC_199      GVVERGSMIPESEGRQVLSAANRAAYVMAATAKEVVSMERAAAETPHTRE
                                                               * :*: :*****:*      :* 

Mflv_3986|M.gilvum_PYR-GCK          YLTPTIAAFTAQLDQGARQYNEMVGAAAQLVSAAN---SGTLS---SSPM
Mvan_2399|M.vanbaalenii_PYR-1       YLAPTITAYTTQLDRGARQYNEMVSAAAQLVSAAN---SGPMS---RSPM
TH_0331|M.thermoresistible__bu      HLEPTIHAFTRQLDHGVRQYNEMVTAAAQLVSAAN---TGQMS---SSPM
MSMEG_2696|M.smegmatis_MC2_155      HLVPTINAFAAQLNQGVRQYNEMVTAAAQLVSSVNGGANGQMPGGPAAPL
Rv2743c|M.tuberculosis_H37Rv        YLVPTINAFTAQLSTGVRQYNEMVTAAAQLVSSAN----GAGG---AGPG
Mb2764c|M.bovis_AF2122/97           YLVPTINAFTAQLSTGVRQYNEMVTAAAQLVSSAN----GAGG---AGPG
MAV_3634|M.avium_104                YLAPTINAFTAQLSAGVRQYNEMVTAAARLVSAAN----GDG-----STA
MMAR_1972|M.marinum_M               QLVPTINAFTAQLGAGVRQYNEMVTAAAQLVSSAN----GATV---AEAV
MUL_3385|M.ulcerans_Agy99           QLVPTINAFTAQLGAGVRQYNEMVTAAAQLVSSAN----GATV---AEAV
MAB_3066c|M.abscessus_ATCC_199      YLQPTIKAFTAQLDTGVRQYNELVTAAAQLVSAGN---GGAVV---ASPM
                                     * *** *:: **. *.*****:* ***:***: *    *        . 

Mflv_3986|M.gilvum_PYR-GCK          SARRYRDELGM-ATDRLKGWAQAFDELG---------------RLRGA--
Mvan_2399|M.vanbaalenii_PYR-1       TQRRYRDELGM-ATDRLTGWAQAFDELG---------------RLKQA--
TH_0331|M.thermoresistible__bu      SQRRYRDELTG-ATDRLVGWAQAFDELG---------------RLRSA--
MSMEG_2696|M.smegmatis_MC2_155      SQQRYRSELTG-ATDRLTGWAQAFDELG---------------GLRRA--
Rv2743c|M.tuberculosis_H37Rv        QQ-RYREELAG-ATDRLVAWAQAFDELG---------------GLPRR--
Mb2764c|M.bovis_AF2122/97           QQ-RYREELAG-ATDRLVAWAQAFDELG---------------GLPRR--
MAV_3634|M.avium_104                SQ-HYRAELVG-ATDRLNGWAQAFDELG---------------GLRGAG-
MMAR_1972|M.marinum_M               SQQRYRHELVG-ATDRLAGWAQAFDELG---------------GLPRR--
MUL_3385|M.ulcerans_Agy99           SQQRYRPNWSELPIARPAGRRPSTNWVGYRAARCAPTCVPSALGSPRRPP
MAB_3066c|M.abscessus_ATCC_199      SRGALFDDLVS-ATDRLTGWAGALDELG---------------QLSG---
                                           :    .  *  .   : : :*                      

Mflv_3986|M.gilvum_PYR-GCK          ------------------
Mvan_2399|M.vanbaalenii_PYR-1       ------------------
TH_0331|M.thermoresistible__bu      ------------------
MSMEG_2696|M.smegmatis_MC2_155      ------------------
Rv2743c|M.tuberculosis_H37Rv        ------------------
Mb2764c|M.bovis_AF2122/97           ------------------
MAV_3634|M.avium_104                ------------------
MMAR_1972|M.marinum_M               ------------------
MUL_3385|M.ulcerans_Agy99           RAAMPWSCRRNRSSRATA
MAB_3066c|M.abscessus_ATCC_199      ------------------