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MSHEHDAGDLDALRAEIEAAERRVAREIEPGARALVVAILVFVLLGSFILPHTGSVRGWDVLFSSHGAGR AAVALPSRVFAWLALVFGVGFSMLALLTRRWALAWVALAGSAMASGTGLLAVWSRQTVAAGHPGPGIGLI VAWITAIVLTFHWAQVVWSRTIVQLAAEERRRRVVAQQQCKTLLDHVQTDSEAGTTPDRGTDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2732c | - | - | 100% (204) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2751c | - | 1e-114 | 100.00% (204) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3966 | - | 2e-59 | 60.96% (187) | putative transmembrane protein |
| M. leprae Br4923 | MLBr_00990 | - | 6e-77 | 76.80% (181) | hypothetical protein MLBr_00990 |
| M. abscessus ATCC 19977 | MAB_3047c | - | 3e-64 | 62.43% (181) | hypothetical protein MAB_3047c |
| M. marinum M | MMAR_1980 | - | 5e-87 | 78.33% (203) | hypothetical protein MMAR_1980 |
| M. avium 104 | MAV_3625 | - | 6e-79 | 75.65% (193) | hypothetical protein MAV_3625 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4642 | - | 2e-68 | 67.78% (180) | PUTATIVE putative conserved transmembrane protein |
| M. ulcerans Agy99 | MUL_3377 | - | 3e-86 | 77.34% (203) | hypothetical protein MUL_3377 |
| M. vanbaalenii PYR-1 | Mvan_2430 | - | 3e-63 | 60.20% (201) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 MRTYQVRTYGCQMNVHDSERLAGLLEAAGYRRAAEGAEVADVVVFNTCAV
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 RENADNKLYGNLSHLAPRKRSNPQMQIAVGGCLAQKDREAVLRRAPWVDV
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 VFGTHNIGSLPTLLERARHNKAAQVEIAEALQQFPSSLPSARESAYAAWV
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 SISVGCNNSCTFCIVPSLRGKEVDRSPDDILAEVRSLVADGVLEVTLLGQ
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 NVNAYGVSFADPALPRDRGAFARLLRACGEIDGLERVRFTSPHPAEFTDD
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 VIEAMAQTPNVCPALHMPLQSGSDRVLRAMRRSYRAERYLGIIDRVRAAM
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 PHAAITTDLIVGFPGETEEDFAATLDVVRRARFAAAFTFQYSKRPGTPAA
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 ELDGQIPKAVVQERYERLVELQESISLQGNQALVGQTVELLVATGEGRKD
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2430|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2732c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2751c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1980|M.marinum_M --------------------------------------------------
MUL_3377|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00990|M.leprae_Br4923 --------------------------------------------------
MAV_3625|M.avium_104 SATARMSGRARDGRLVHFAADDRVRPGDLVTTVITGAAPHHLIADAGILS
TH_4642|M.thermoresistible__bu --------------------------------------------------
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3966|M.gilvum_PYR-GCK ---------------------------------------MSPDP----G-
Mvan_2430|M.vanbaalenii_PYR-1 ---------------------------------------MNAEAHGANG-
Rv2732c|M.tuberculosis_H37Rv --------------------------------------MMSHEHDAGDL-
Mb2751c|M.bovis_AF2122/97 --------------------------------------MMSHEHDAGDL-
MMAR_1980|M.marinum_M ---------------------------------------MNGEVDVADF-
MUL_3377|M.ulcerans_Agy99 ---------------------------------------MNGEVDVADF-
MLBr_00990|M.leprae_Br4923 ---------------------------------------MNEEPNIVDFP
MAV_3625|M.avium_104 HRRTRAGDAHAPAGARAASVSACPPSGRRRPGPTRWMCLMNDDRNHDDP-
TH_4642|M.thermoresistible__bu ------------------------------------VWLLSAEGSDRDDS
MAB_3047c|M.abscessus_ATCC_199 --------------------------------------MNDSEPGKEDAE
. :
Mflv_3966|M.gilvum_PYR-GCK --------FDDFKRDIDAAEKRVAREIDPGPRALV-IAILVFVLLVTLLL
Mvan_2430|M.vanbaalenii_PYR-1 --------FDQFKGDLEAAERRIAREIDPGVRALF-LAILVFVLLATLLL
Rv2732c|M.tuberculosis_H37Rv ---------DALRAEIEAAERRVAREIEPGARALV-VAILVFVLLGSFIL
Mb2751c|M.bovis_AF2122/97 ---------DALRAEIEAAERRVAREIEPGARALV-VAILVFVLLGSFIL
MMAR_1980|M.marinum_M ---------DAYRSEIEAAERRVAREIDPGARALV-VAILVFVLLGSFIL
MUL_3377|M.ulcerans_Agy99 ---------DAYRSEIEAAERRVARETDPGARALV-VAILVFVLLGSFIL
MLBr_00990|M.leprae_Br4923 -------DSNPLQAALEAEELRVVREIDSGAKIFVLIAVLVFMLLGSFIL
MAV_3625|M.avium_104 -------RLGALRTEIEAAERRVAGGIDPGARGFV-VSILVFVLLGSFIL
TH_4642|M.thermoresistible__bu RGRREHDDLDEFRSEIEAAERRLAGEFDPGARALV-VAILVFVILVTFVL
MAB_3047c|M.abscessus_ATCC_199 FD-----EFAAFHKDIDAAEKKVAGEIDPGARAMV-VAVLVFALLLTFVL
: ::* * ::. :.* : :. :::*** :* :::*
Mflv_3966|M.gilvum_PYR-GCK PHTGTARGLDVLTGSQAAVDNGVILPHRVFAILLVVFGAGFSMVALLTRR
Mvan_2430|M.vanbaalenii_PYR-1 PHTGGARGLDVLTGSGAAVDNGVALPSRVFAWFSLVFGVGFSMLALLTRR
Rv2732c|M.tuberculosis_H37Rv PHTGSVRGWDVLFSSHGAGRAAVALPSRVFAWLALVFGVGFSMLALLTRR
Mb2751c|M.bovis_AF2122/97 PHTGSVRGWDVLFSSHGAGRAAVALPSRVFAWLALVFGVGFSMLALLTRR
MMAR_1980|M.marinum_M PHTGNVRGWDVLFSSNGATDAAVTLPSQVFAWLTLVFGVGFSMLALMTRR
MUL_3377|M.ulcerans_Agy99 PHTGNVRGWDVLFSSNGATDAAVTLPSQVFAWLTLVFGVGFSMLALMTRR
MLBr_00990|M.leprae_Br4923 PHTGQVRGWDVLFDSHGAGAAAVALPLRIFAWLSLVFGVGFSMLALMTRR
MAV_3625|M.avium_104 PHTGDVRGWDVLFGTHDAGAAAVALPSRVFGWLALVFGVGFSTLALVTRR
TH_4642|M.thermoresistible__bu PHTGGVRGWDVLLGGEAAGAAGVSLPSRVFGWCTLVFSVGFSMIALLTRR
MAB_3047c|M.abscessus_ATCC_199 PHTGHARGFDVLVNGAIADQEAVRVPSRIFVWLAMIFGVGFSMLALLTRR
**** .** *** . * .* :* ::* ::*..*** :**:***
Mflv_3966|M.gilvum_PYR-GCK WALAWIALAGSTVASFLGVLALWTRQTAPEPYPGPGFGLIIAWLTAIVLS
Mvan_2430|M.vanbaalenii_PYR-1 WTLAWIALAGSTVAAFLGLLAVWSRQTAPEPYPGPGLGLITAWFAVILLT
Rv2732c|M.tuberculosis_H37Rv WALAWVALAGSAMASGTGLLAVWSRQTVAAGHPGPGIGLIVAWITAIVLT
Mb2751c|M.bovis_AF2122/97 WALAWVALAGSAMASGTGLLAVWSRQTVAAGHPGPGIGLIVAWITAIVLT
MMAR_1980|M.marinum_M WTLAWVALAGSALASGTGLLAVWSRQTVAAGQPGPGVGLIVSWIAVILLT
MUL_3377|M.ulcerans_Agy99 WTLAWVALAGSALASGTGLLAVWSRQTVAAGQPGPGVGLIVSWIAVILLT
MLBr_00990|M.leprae_Br4923 WVLAWIALAGAAMASIVGLLAVWSRQTVAVGQPGPGVGLIVAWITLILLT
MAV_3625|M.avium_104 WALAWIALAGTAIAGAAGMLAIWSRQTVPAGHPGPGWGLIVAWITVLVLI
TH_4642|M.thermoresistible__bu WALAWVALAGSAVASAFGMLAIWSRQTAAEQYPGPGFGLVIAWIAVMVLT
MAB_3047c|M.abscessus_ATCC_199 WVLSWIALAGSFVASVIGMLAIWTRQTAGSGHPGPGIGLVIAWIAVILLT
*.*:*:****: :*. *:**:*:***. **** **: :*:: ::*
Mflv_3966|M.gilvum_PYR-GCK YHWARVVATRSALQLAAEEDRRRADAEGQNKGLLETFITDDDGDGPPK--
Mvan_2430|M.vanbaalenii_PYR-1 YHWARVVATRTALQLAAEEQRRRADSEGQNKSLLATFPDEGDND-PPKE-
Rv2732c|M.tuberculosis_H37Rv FHWAQVVWSRTIVQLAAEERRRRVVAQQQCKTLLDHVQT--DSEAGTTPD
Mb2751c|M.bovis_AF2122/97 FHWAQVVWSRTIVQLAAEERRRRVVAQQQCKTLLDHVQT--DSEAGTTPD
MMAR_1980|M.marinum_M FHWARVVWQRTIVQLAAEEQRRRVVAEQQSQTLLDSFNTP-DESDGTAAE
MUL_3377|M.ulcerans_Agy99 FHWARVVWQRTIVQLAAEEQRRRVAAEQQSQTLLDSFNTP-DESDGTAAE
MLBr_00990|M.leprae_Br4923 FHWARVVWSSTIVQLATEEQRRRVVAQQQSKTLLDGLYSAGNRDTRTRSD
MAV_3625|M.avium_104 YQWARVVWSRTIVQLAAEEQRRRVAAQQQSTTLLDDLPKPEDPAAGT---
TH_4642|M.thermoresistible__bu FHWARAVWARTDLQMAAEADRRRRAAERHLRSLDPDASDPAVDREAHLDS
MAB_3047c|M.abscessus_ATCC_199 FHWARVVWSRTAVQLAAEQERREAAKRDQRTILDDAFEDDEDRDK-----
::**:.* : :*:*:* **. . : *
Mflv_3966|M.gilvum_PYR-GCK ---------------
Mvan_2430|M.vanbaalenii_PYR-1 ---------------
Rv2732c|M.tuberculosis_H37Rv RGTDR----------
Mb2751c|M.bovis_AF2122/97 RGTDR----------
MMAR_1980|M.marinum_M KDQD-----------
MUL_3377|M.ulcerans_Agy99 KDQD-----------
MLBr_00990|M.leprae_Br4923 PQVGS----------
MAV_3625|M.avium_104 ---------------
TH_4642|M.thermoresistible__bu PDVTGPDDRGDEHGR
MAB_3047c|M.abscessus_ATCC_199 ---------------