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TKYRGQFELNRPATLIAALPAILGFVPEKSLVLVSLAAGELGSVMRADLCDELADRVGHLAELVAAANPA AAIAVIVDANGAQCPRCNEEYRQLCAALAAALSQRDIVLWAAHVVDRVAAGGRWHCVDGCGCSGVIDDPS ASPLAMAAVLDGRQLYPRRSDLQAVIAVDDPVRSAELAVALGHQAADREIAHRADSVGCSRQDVENALAA AARVADGQSLSDTELARLGCALGDARVRDMLYALAVGENAGAAESLWALLARVLPEPWRVEALVLLAFSA YARGDGPLAGVSLQAALCCEPGHRMAGMLDTALQSGLRPEHIRDIAVTGYQRAEQLGIRLPPRRAFGQRA G*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2712c | - | - | 100% (352) | hypothetical protein Rv2712c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2731c | - | 0.0 | 100.00% (352) | hypothetical protein Mb2731c |
| M. gilvum PYR-GCK | Mflv_3950 | - | 1e-109 | 62.10% (343) | hypothetical protein Mflv_3950 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3030c | - | 5e-74 | 47.86% (351) | hypothetical protein MAB_3030c |
| M. marinum M | MMAR_2001 | - | 1e-150 | 75.86% (348) | hypothetical protein MMAR_2001 |
| M. avium 104 | MAV_3605 | - | 1e-143 | 74.22% (353) | hypothetical protein MAV_3605 |
| M. smegmatis MC2 155 | MSMEG_2749 | - | 1e-112 | 60.70% (341) | hypothetical protein MSMEG_2749 |
| M. thermoresistible (build 8) | TH_1488 | - | 1e-71 | 63.96% (222) | HYPOTHETICAL PROTEIN Rv2712c |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2449 | - | 1e-106 | 58.69% (351) | hypothetical protein Mvan_2449 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2712c|M.tuberculosis_H37Rv ---------------------------------------MTK-----YRG
Mb2731c|M.bovis_AF2122/97 ---------------------------------------MTK-----YRG
MMAR_2001|M.marinum_M ---------------------------------------MTK-----HRS
MAV_3605|M.avium_104 ---------------------------------------MTT-----HRQ
Mflv_3950|M.gilvum_PYR-GCK ---------------------------------------MASRHH-PENH
Mvan_2449|M.vanbaalenii_PYR-1 ---------------------------------------MATTPR-PYS-
MSMEG_2749|M.smegmatis_MC2_155 MAREQFVSEVVPRADFVHSHSSQPVFGVNGVGAGCHGRHMTP----SPHT
TH_1488|M.thermoresistible__bu --------------------------------------------------
MAB_3030c|M.abscessus_ATCC_199 ---------------------------------------MTSLIPGPAGR
Rv2712c|M.tuberculosis_H37Rv -QFELNRPATLIAALPAILGFVPEKSLVLVSLAAGELGSVMRADLCDELA
Mb2731c|M.bovis_AF2122/97 -QFELNRPATLIAALPAILGFVPEKSLVLVSLAAGELGSVMRADLCDELA
MMAR_2001|M.marinum_M -EFELNRPAALIAALPAILGFVPEKSLVLVSLDDGELGSVLRADLSEDLV
MAV_3605|M.avium_104 PDFTLSRPGALIAALPAVLGFVPESSLVLVSLEDGRLGSVLRVDLSDELA
Mflv_3950|M.gilvum_PYR-GCK LDISLNRPGALIAALPAVLGFTPESSLVLVTVAHGELGAVLRGDLSDQSP
Mvan_2449|M.vanbaalenii_PYR-1 ---SLDRPGALIAALPAVLGFVPERSLVLVTVADADMGAVLRADLSDPPP
MSMEG_2749|M.smegmatis_MC2_155 PDFRINRPGSLIAALPAVLGFVPEKSLVLATIESGELGCVLRTDLSLAMR
TH_1488|M.thermoresistible__bu --------------------------------------------------
MAB_3030c|M.abscessus_ATCC_199 PDFRLDRPSALIAALPAMLGFIPEDSLVVVTLADGLIEAVLRRDLRDLDN
Rv2712c|M.tuberculosis_H37Rv DRVGHLAELVAAANPAAAIAVIVDANGAQCPRCNEEYRQLCAALAAALSQ
Mb2731c|M.bovis_AF2122/97 DRVGHLAELVAAANPAAAIAVIVDANGAQCPRCNEEYRQLCAALAAALSQ
MMAR_2001|M.marinum_M DRVEHLAEVAGAADPQAAIAVIVDEGGAQCPACNEVYRRVCAALAEALSQ
MAV_3605|M.avium_104 HRVDHLAEVTAAARPEAVIAVIVDAAGAPCPSCNEDYRQLCDALLEALAR
Mflv_3950|M.gilvum_PYR-GCK QRLCELAELAAASGADAAIAVIVDDEGAGCAMCADEHREATSTLGDELAR
Mvan_2449|M.vanbaalenii_PYR-1 DQLCQLAELAAAAGAETAIAVIVDDSGAGCAMCADEHRRLANTLTDELDA
MSMEG_2749|M.smegmatis_MC2_155 EGTAHLAEVAAAGEPHAVIAVIVDADGADCVHCHENHATLAEDVAIELSA
TH_1488|M.thermoresistible__bu -------------------------------MCRPXX-------------
MAB_3030c|M.abscessus_ATCC_199 PEHAAFEALAAVLGPGPADAVIAVVISP--VLDELEAGDIIRRLAKHLEY
Rv2712c|M.tuberculosis_H37Rv RDIVLWAAHVVDRVAAGGRWHCVDGCGCSGVIDDPSASPLAMAAVLDGRQ
Mb2731c|M.bovis_AF2122/97 RDIVLWAAHVVDRVAAGGRWHCVDGCGCSGVIDDPSASPLAMAAVLDGRQ
MMAR_2001|M.marinum_M HNVVLRAAHVVDQIAVGGRWHCVDGCGSSGLIDDPAASPLAVAAVLDGRR
MAV_3605|M.avium_104 NDIELYAAHVVDRVALGGRWHCVDGCGASGLIDDPSASPLAAAAVLDGRR
Mflv_3950|M.gilvum_PYR-GCK VGVELMAAHVVPEVAAGARWYCVDGCGSSGVVDDPMASPTALAAVLDGRR
Mvan_2449|M.vanbaalenii_PYR-1 HGVELAAAYVVAEIAGGARWYCVDGCGNSGVVEDPTASPTAVAAVLDGRR
MSMEG_2749|M.smegmatis_MC2_155 RGIELLAVHVVDRIDAGGRWHCADGCGRNGVVEDPYASPLALAAVLDGRR
TH_1488|M.thermoresistible__bu ------------------------XCGAGGRVEDPSASPLAAAAVLDGRR
MAB_3030c|M.abscessus_ATCC_199 HGVSLIAGHVVDRVGAHGWWRCYDGCGAGGPVDDPQCSPLTAAAVLAGRT
** .* ::** .** : **** **
Rv2712c|M.tuberculosis_H37Rv LYPRRSDLQAVIAVDDPVRSAELAVALGHQAADREIAHRADSVGCSRQDV
Mb2731c|M.bovis_AF2122/97 LYPRRSDLQAVIAVDDPVRSAELAVALGHQAADREIAHRADSVGCSRQDV
MMAR_2001|M.marinum_M LYPRRADLQAVVELDESARAGELAGALAEHAAEREISYRADPSRCARRDV
MAV_3605|M.avium_104 LYARRADLQAVIAVEDPERSAALTAAVRRQAGRRTAALRANPVRRTRGDV
Mflv_3950|M.gilvum_PYR-GCK LYARRDELLDVVATVDGRRTGALAAVIEQAAPP--EAPRPDSQ--ARHDI
Mvan_2449|M.vanbaalenii_PYR-1 LYRRRDELVAVVATADSARAAALGRKIESASAP--DPSRPDSE--ARSDV
MSMEG_2749|M.smegmatis_MC2_155 LYKRRADLQAVVAA-DPVRAEKIAEAISAVAPR--SGRRRLSA--VRADI
TH_1488|M.thermoresistible__bu LYTRRSELVAVVEP-APDRDPDLAEAITRTAERR-GELRTDAQ--ARRDV
MAB_3030c|M.abscessus_ATCC_199 VHRRREDLVALIAPTDTTRTAALAVSLRRPFQG-----PCDTAAADRRAV
:: ** :* :: * : : . * :
Rv2712c|M.tuberculosis_H37Rv ENALAAAARVADGQSLSDTELARLGCALGDARVRDMLYALAVGENAGAAE
Mb2731c|M.bovis_AF2122/97 ENALAAAARVADGQSLSDTELARLGCALGDARVRDMLYALAVGENAGAAE
MMAR_2001|M.marinum_M ESAMAAAARVADGQSLSEVELARLGCALTDVQVRDTLYALAVGENADEAE
MAV_3605|M.avium_104 EKAMAAAARVSSGEALSDTELARLGCALSDPQVRDMLYALAVGEGADEVE
Mflv_3950|M.gilvum_PYR-GCK EHALECARRNEAGDTLSDDDLSRLAWALTDTRVRDTLYALAVGEAAGTAE
Mvan_2449|M.vanbaalenii_PYR-1 EHALACVERGERDRPLADADLVRLAWSLTDARVRDTLYALAVGDSAGAAE
MSMEG_2749|M.smegmatis_MC2_155 NAAITAAARLADGRTLTVRQQARIALALTDTRVRDTLYALAIGETAGQAE
TH_1488|M.thermoresistible__bu QDMIAAAGRIAAGSDIGEPQLCALACALTDGRVRDTLYALAVGDDAAIAE
MAB_3030c|M.abscessus_ATCC_199 NRVMRTACRAAEFRPLSNREILAIARSLMALRVRDTLCALAVGALAADVE
: : . * : : :. :* :*** * ***:* * .*
Rv2712c|M.tuberculosis_H37Rv SLWALLARVLPEPWRVEALVLLAFSAYARGDGPLAGVSLQAALCCEPGHR
Mb2731c|M.bovis_AF2122/97 SLWALLARVLPEPWRVEALVLLAFSAYARGDGPLAGVSLQAALCCEPGHR
MMAR_2001|M.marinum_M SLWGVLARALPAPWRAEALVLLAFSAYVRGDGPLTGVSLDAALRCAPGHR
MAV_3605|M.avium_104 SLWAVLARTLPEPWRVEALVLVAFSAYARGDGPLAGVSLVEALRCEPGHR
Mflv_3950|M.gilvum_PYR-GCK ALWAELSRTLPEPWRVEALVLLAFSAYVRGDGPLAGISLDAALRHAP-HR
Mvan_2449|M.vanbaalenii_PYR-1 AVWAELARRLPEPWRVEALVLLAFSAYARGDGPLAGISLDQALRGEPLHN
MSMEG_2749|M.smegmatis_MC2_155 SLWAELSRSLPAPWRVEALVQLAFSAYVRGDGPLAGIALDAALRCIPTHR
TH_1488|M.thermoresistible__bu NLWAWLARMLPEPWRTEALVLLAFSAYARGDGPLAGVSLDAALRGDPNHR
MAB_3030c|M.abscessus_ATCC_199 RLWLALSRLLPPPWRAEALVLLGFSAYVRGDGPLAGVALDAALMAQADHR
:* *:* ** ***.**** :.****.******:*::* ** . *.
Rv2712c|M.tuberculosis_H37Rv MAGMLDTALQSGLRPEHIRDIAVTGYQRAEQLGIRLPPRRA---FGQRAG
Mb2731c|M.bovis_AF2122/97 MAGMLDTALQSGLRPEHIRDIAVTGYQRAEQLGIRLPPRRA---FGQRAG
MMAR_2001|M.marinum_M MAGMLDTALQSGLRPEHIRDLAVTGYRLAKQLGVQLPPRRASGPYGRCAG
MAV_3605|M.avium_104 MAGMLDTALQSGLRPEDIRDLARTGYRLAKQFGVRLPPRRP---FGRRAG
Mflv_3950|M.gilvum_PYR-GCK MAGMLDRALQCGMRPEQIRELATTGYRLAAQLGVRLPPRRL---FGRRVG
Mvan_2449|M.vanbaalenii_PYR-1 MAGMLEHALRSGMRPEQIRELARTGYRLAQQLGVRLPPRRL---FGRRAG
MSMEG_2749|M.smegmatis_MC2_155 MASMLDTALQSGMPPDQVRELALTGYRQAERLGVQLPPRRTFGDGLRSAG
TH_1488|M.thermoresistible__bu MAGMLDTALQSGLRPERIRELALTGYRMADRLGVRLPPRRA---FGRAG-
MAB_3030c|M.abscessus_ATCC_199 LGQLLMSALLSGMRPDEIGTLADTGYRIAHELGISLPPRQI-----RRAG
:. :* ** .*: *: : :* ***: * .:*: ****: :
Rv2712c|M.tuberculosis_H37Rv -
Mb2731c|M.bovis_AF2122/97 -
MMAR_2001|M.marinum_M -
MAV_3605|M.avium_104 -
Mflv_3950|M.gilvum_PYR-GCK -
Mvan_2449|M.vanbaalenii_PYR-1 -
MSMEG_2749|M.smegmatis_MC2_155 A
TH_1488|M.thermoresistible__bu -
MAB_3030c|M.abscessus_ATCC_199 -