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MTSTGPETSETPGATTQRHGFGIDVGGSGIKGGIVDLDTGQLIGDRIKLLTPQPATPLAVAKTIAEVVNG FGWRGPLGVTYPGVVTHGVVRTAANVDKSWIGTNARDTIGAELGGQQVTILNDADAAGLAETRYGAGKNN PGLVVLLTFGTGIGSAVIHNGTLIPNTEFGHLEVGGKEAEERAASSVKEKNDWTYPKWAKQVIRVLIAIE NAIWPDLFIAGGGISRKADKWVPLLENRTPVVPAALQNTAGIVGAAMASVADTTH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2702 | ppgK | - | 100% (265) | POLYPHOSPHATE GLUCOKINASE PPGK (POLYPHOSPHATE-GLUCOSE PHOSPHOTRANSFERASE) |
| M. tuberculosis H37Rv | Rv0650 | - | 1e-06 | 24.26% (305) | sugar kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2721 | ppgK | 1e-152 | 99.62% (265) | polyphosphate glucokinase PPGK (polyphosphate-glucose |
| M. gilvum PYR-GCK | Mflv_3938 | - | 1e-113 | 74.62% (264) | polyphosphate--glucose phosphotransferase |
| M. leprae Br4923 | MLBr_01023 | ppgK | 1e-123 | 81.65% (267) | polyphosphate glucokinase |
| M. abscessus ATCC 19977 | MAB_3008 | - | 1e-108 | 71.15% (260) | polyphosphate glucokinase PpgK |
| M. marinum M | MMAR_2012 | ppgK | 1e-126 | 83.77% (265) | polyphosphate glucokinase PpgK |
| M. avium 104 | MAV_3594 | - | 1e-121 | 79.55% (269) | polyphosphate glucokinase |
| M. smegmatis MC2 155 | MSMEG_2760 | - | 1e-115 | 76.65% (257) | polyphosphate glucokinase |
| M. thermoresistible (build 8) | TH_0826 | ppgK | 1e-110 | 73.00% (263) | POLYPHOSPHATE GLUCOKINASE PPGK (POLYPHOSPHATE-GLUCOSE |
| M. ulcerans Agy99 | MUL_3340 | ppgK | 1e-124 | 83.02% (265) | polyphosphate glucokinase PpgK |
| M. vanbaalenii PYR-1 | Mvan_2462 | - | 1e-110 | 75.00% (252) | polyphosphate--glucose phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3938|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2462|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2760|M.smegmatis_MC2_155 --------------------------------------------------
Rv2702|M.tuberculosis_H37Rv --------------------------------------------------
Mb2721|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01023|M.leprae_Br4923 MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEI
MMAR_2012|M.marinum_M --------------------------------------------------
MUL_3340|M.ulcerans_Agy99 --------------------------------------------------
MAV_3594|M.avium_104 --------------------------------------------------
MAB_3008|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0826|M.thermoresistible__bu --------------------------------------------------
Mflv_3938|M.gilvum_PYR-GCK -MTADAE----PSSSVPQ--------RRGFGIDVGGSGVKGGIVDLDTGA
Mvan_2462|M.vanbaalenii_PYR-1 -MTADAE----PSPSAAAAESGSGSPRRGFGIDVGGSGVKGGIVDLDTGR
MSMEG_2760|M.smegmatis_MC2_155 -MTAQDQ----PTADPTTAG---TTGRRGFGVDVGGSGVKGGIVDLDTGK
Rv2702|M.tuberculosis_H37Rv -MTSTG-----PETS---ETPGATTQRHGFGIDVGGSGIKGGIVDLDTGQ
Mb2721|M.bovis_AF2122/97 -MTSTG-----PETS---ETPGATTQRHGFGIDVGGSGIKGGIVDLDTGQ
MLBr_01023|M.leprae_Br4923 AITSTDATADTPRTSPPSDTAGTTSRHRGFGIDIGGSSIKGGIVDLDIGQ
MMAR_2012|M.marinum_M -MTSTD-----PMAQ----TAGAAQPHRGFGIDVGGSGIKGAIVDLDTGQ
MUL_3340|M.ulcerans_Agy99 -MTSTD-----PMAQ----TAGAAQPHRGFGIDVGGSGIKGAIVDLDTGQ
MAV_3594|M.avium_104 -MTSTDSTAHTPAAP-----AAGPPPRRGFGVDVGGSGIKGGIVDMDTGL
MAB_3008|M.abscessus_ATCC_1997 -MTATDS---APAAT---AADPSNTPQQAFGIDVGGSGIKGAIVDLTTGE
TH_0826|M.thermoresistible__bu -MTATDS---SVTPP---AADG--AERRAFGIDIGGSGVKGGVVDLNTGR
:*: . ::.**:*:***.:**.:**: *
Mflv_3938|M.gilvum_PYR-GCK LIGERFKLLTPQPATPEAVAKTIADVVAHFEWTGPLGVTYPGVVADGIVR
Mvan_2462|M.vanbaalenii_PYR-1 LVGDRFKLLTPQPATPDAVSKTIADVAAHFDWEGPLGVTYPGVVADGIVC
MSMEG_2760|M.smegmatis_MC2_155 LVGERFKLDTPQPATPEAVAKTVAAVVREFGWTGKLGVTYPGVVTGGIVR
Rv2702|M.tuberculosis_H37Rv LIGDRIKLLTPQPATPLAVAKTIAEVVNGFGWRGPLGVTYPGVVTHGVVR
Mb2721|M.bovis_AF2122/97 LIGDRIKLLTPQPATPLAVAKTIAEVVNGFGWRGPLGVTYPGVVTHGVVR
MLBr_01023|M.leprae_Br4923 LIGDRIKLLTPQPATPLAVAKTIAEVVNAFGWTAPLGVTYPGVVTQGVVR
MMAR_2012|M.marinum_M LIGERIKLATPQPATPSAVAKTIAEVVDRFGWTGPLGVTYPGVVTHGIVQ
MUL_3340|M.ulcerans_Agy99 LIGERIKLATPQPATPSAVAKTIAEVVDQIGWTGPLGVTYPGVVTHGIVQ
MAV_3594|M.avium_104 LIGERVKLLTPQPATPSAVAKTIAAVVDAFEWTGPLGVTYPGVVTHGVVQ
MAB_3008|M.abscessus_ATCC_1997 MVGERVKYPTPQPATPKAVAETIARVVRDFSWTGPVGVTYPGVIVRGEAR
TH_0826|M.thermoresistible__bu LIGDRYKLPTPQPALPDAVAETVAAVVREFGWTGRLGVTYPGVVIDGVAH
::*:* * ***** * **::*:* *. : * . :*******: * .
Mflv_3938|M.gilvum_PYR-GCK TAANVDKAWIGLNAKEVISAALGGQSVTVLNDADAAGLAEEKFGAGRNNT
Mvan_2462|M.vanbaalenii_PYR-1 TAANVDKGWLGLNAKEVIGGALSGQPVTVLNDADAAGLAEEKFGAGRDKT
MSMEG_2760|M.smegmatis_MC2_155 TAANVDKGWIGVNAVETISKALDGQEVTVLNDADAAGLAEERFGAGKDNS
Rv2702|M.tuberculosis_H37Rv TAANVDKSWIGTNARDTIGAELGGQQVTILNDADAAGLAETRYGAGKNNP
Mb2721|M.bovis_AF2122/97 TAANVDKSWIGTNARDTIGAELGGQQVTILNDADAAGLAETRYGAGKNNP
MLBr_01023|M.leprae_Br4923 TAANVDDSWIGTNARDIISAELNSQEVTILNDADAAGLAEGRYGAGKNNS
MMAR_2012|M.marinum_M TAANVDKSWIGTNAREVISAELNGQDVTILNDADAAGLAEERYGAGNNQP
MUL_3340|M.ulcerans_Agy99 TAANLDKSWIGTNAREVISAELNGQDVTILNDADAAGLAEERYGAGNNQP
MAV_3594|M.avium_104 TAANVDKAWIGTNARDIISAELNGQEVTVLNDADAAGLAEEHYGAGRNQS
MAB_3008|M.abscessus_ATCC_1997 TAANVDKSWLGVNVHDIISTELGGQTVTVLNDADAAGLAEDRYGAGKDQS
TH_0826|M.thermoresistible__bu TAANVDKSWLGTNVRSVLERELDGQPVTVLNDADAAGIAEERYGAGRDQD
****:*..*:* *. . : *..* **:********:** ::***.::
Mflv_3938|M.gilvum_PYR-GCK GVIVLLTFGTGIGSAVIHNGVLLPNTEFGHLEVGGKEAEHRAASSVKERK
Mvan_2462|M.vanbaalenii_PYR-1 GVIVLLTFGTGIGSAVIHNGVLLPNTEFGHLEVGGKEAEHRAASSVKEAK
MSMEG_2760|M.smegmatis_MC2_155 GVIVLLTFGTGIGSAVIHNGVLLPNTEFGHLEVGGKEAEHRAASSVKERK
Rv2702|M.tuberculosis_H37Rv GLVVLLTFGTGIGSAVIHNGTLIPNTEFGHLEVGGKEAEERAASSVKEKN
Mb2721|M.bovis_AF2122/97 GLVVLLTFGTGIGSAVIHNGTLIPNTEFGHLEVGGKEAEERAASSVKEKN
MLBr_01023|M.leprae_Br4923 GLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQRAASSVKDKY
MMAR_2012|M.marinum_M GLVVLLTFGTGIGSAVINNGTLIPNTEFGHLEVGGKEAEQRAASSIKEKN
MUL_3340|M.ulcerans_Agy99 GLVVLLTFGTGIGSAVINDGTLIPNTEFGHLEVGGKEAEQRAASSVKEKN
MAV_3594|M.avium_104 GLVVLLTFGTGIGSAVIHNGTLIPNTELGHLEVGGKEAEQRAASSVKERH
MAB_3008|M.abscessus_ATCC_1997 GVVVLLTFGTGIGSAVLHNGILLPNTEFGHIQVDGMEAEHRAASSVKEKN
TH_0826|M.thermoresistible__bu GVVVLLTFGTGIGSAVIHNGVLLPNTEFGHIEVGGMEAEHRAASSVKERN
*::*************:::* *:****:**::*.* ***.*****:*:
Mflv_3938|M.gilvum_PYR-GCK EWTHERWTVEVTKVLVAIENAIWPDLFIAGGGISRKAAKWIPLLKNRVPV
Mvan_2462|M.vanbaalenii_PYR-1 GWSYERWTTEVTKVLVAIENAIWPDLFIVGGGISRKADKWVPLLQNRTPV
MSMEG_2760|M.smegmatis_MC2_155 DWSYSRWSEEVTKVLITIENAIWPDLFIAGGGISRKADKWIPMLKNRTPV
Rv2702|M.tuberculosis_H37Rv DWTYPKWAKQVIRVLIAIENAIWPDLFIAGGGISRKADKWVPLLENRTPV
Mb2721|M.bovis_AF2122/97 DWTYPKWAKQVTRVLIAIENAIWPDLFIAGGGISRKADKWVPLLENRTPV
MLBr_01023|M.leprae_Br4923 KWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPM
MMAR_2012|M.marinum_M DWSYEKWTKQVTRVLVAIENAIWPDLFIVGGGISRKADKWVHLLENRTPV
MUL_3340|M.ulcerans_Agy99 DWSYEKWTKQVTRVLVAIENAIWPDLFIVGGGISRKADKWVHLLENRTPV
MAV_3594|M.avium_104 GWSYEKWAKQVTRVLVSIENALWPDLFIAGGGISRKADKWLPLLENRTPV
MAB_3008|M.abscessus_ATCC_1997 DWSYKQWAPEVTKVLEAVENALWPDLFIVGGGISRKADKWVPLLTNRTPV
TH_0826|M.thermoresistible__bu DWSYKRWTTEVTKVLIAIENAIWPDLFIVGGGISRKAEKWVPLLENRTPV
*:: *: :* :** ::***: *****.******** :*: :* **.*:
Mflv_3938|M.gilvum_PYR-GCK VAAELQNTAGIVGAAMAAESDVTATGREHH--
Mvan_2462|M.vanbaalenii_PYR-1 VAAELQNTAGIVGAAMASDVDVTATGK-----
MSMEG_2760|M.smegmatis_MC2_155 VAAALQNTAGIVGAAMASVVDVQATGGQQL--
Rv2702|M.tuberculosis_H37Rv VPAALQNTAGIVGAAMASVADTTH--------
Mb2721|M.bovis_AF2122/97 VPAALQNTAGIVGAAMASVADTTH--------
MLBr_01023|M.leprae_Br4923 VAAALQNTAGIVGAAMASTADVTH--------
MMAR_2012|M.marinum_M VAATLQNTAGIVGAAMASSTDVTH--------
MUL_3340|M.ulcerans_Agy99 VAATLQNTAGIVGAAMASSTDVTH--------
MAV_3594|M.avium_104 VAAALLNTAGIVGAAMAATSDVTH--------
MAB_3008|M.abscessus_ATCC_1997 VAAALQNTAGIVGAAMAAHAGVSP--------
TH_0826|M.thermoresistible__bu VPAALRNTAGIVGAAMAAEFDVTATTAASRSM
*.* * ***********: ..