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M. tuberculosis H37Rv Rv2611c (-)

annotation: lipid A biosynthesis lauroyl acyltransferase
coordinates: 2939012 - 2939962
length: 316

IAGLKGLKLPKDPRSSVTRTATDWAYAAGWMAVRALPEFAVRNAFDTGARYFARHGGPEQLRKNLARVLG
VPPAAVPDPLMCASLESYGRYWREVFRLPTINHRKLARQLDRVIGGLDHLDAALAAGLGAVLALPHSGNW
DMAGMWLVQRHGTFTTVAERLKPESLYQRFIDYRESLGFEVLPLSGGERPPFEVLSERLRNNRVVCLMAE
RDLTRTGVEVDFFGEPTRMPVGPAKLAVETGAALLPTHCWFEGRGWGFQVYPALDCTSGDVAAITQALAD
RFAQNIAAHPADWHMLQPQWLADLSESRRAQLRSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2611c--100% (316)lipid A biosynthesis lauroyl acyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2643c-0.099.37% (316) lipid A biosynthesis lauroyl acyltransferase
M. gilvum PYR-GCKMflv_3835-1e-11464.09% (298) lipid A biosynthesis lauroyl acyltransferase
M. leprae Br4923MLBr_00453-1e-13070.44% (318) lipid A biosynthesis lauroyl acyltransferase
M. abscessus ATCC 19977MAB_2895c-1e-10863.39% (295) lipid A biosynthesis lauroyl acyltransferase
M. marinum MMMAR_2091-1e-14679.30% (314) acyltransferase
M. avium 104MAV_3487-1e-13276.98% (291) lipid A biosynthesis lauroyl acyltransferase
M. smegmatis MC2 155MSMEG_2934-1e-12773.88% (291) lipid A biosynthesis lauroyl acyltransferase
M. thermoresistible (build 8)TH_1810-1e-12572.00% (300) PROBABLE ACYLTRANSFERASE
M. ulcerans Agy99MUL_3253-1e-14578.66% (314) lipid A biosynthesis lauroyl acyltransferase
M. vanbaalenii PYR-1Mvan_2561-1e-12672.70% (293) lipid A biosynthesis lauroyl acyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Rv2611c|M.tuberculosis_H37Rv        MIAGLKGLKLPKDP----RSSVTRTATDWAYAAGWMAVRALPEFAVRNAF
Mb2643c|M.bovis_AF2122/97           MIAGLKGLKLPKDP----RSSVTRTATDWAYAAGWMAVRALPEFAVRNAF
MMAR_2091|M.marinum_M               MISTPAGLRWVRAP----RQLLVGNATDLAYAAGWRMVRALPEFAARNAF
MUL_3253|M.ulcerans_Agy99           MISTPAGLRWVRAP----RQLLVGNATDLAYAAGWRMVRALPEFAARNAF
MLBr_00453|M.leprae_Br4923          MTTSTAGLKMIRAP----HRLMTGRAIDWAYAAGWRAVRAMPESAARFAF
MAV_3487|M.avium_104                MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAF
Mflv_3835|M.gilvum_PYR-GCK          MTRD-QGAVRDGGGLLAFPSALAGQLSDWGYAAGWRLVRAAPDILARNTF
Mvan_2561|M.vanbaalenii_PYR-1       MTQHPAGSGSDNGRLLSFG----GHLTDWGYAAGWRLVRAAPEFLARNAF
TH_1810|M.thermoresistible__bu      --------VSDGADSPLTG-----RLSDWSYAAGWRLVRALPESVARGAF
MSMEG_2934|M.smegmatis_MC2_155      --------MTLSGRIPLGG-----QVTDLGYAAGWRLVRAMPEAMAQGVF
MAB_2895c|M.abscessus_ATCC_199      --------MSVWGE----------RAADWGYAAGWNLTQITPDLLARAIF
                                                               * .**:**  .:  *:  .:  *

Rv2611c|M.tuberculosis_H37Rv        DTGARYFARHGGPEQLRKNLARVLGVPPAAVPDPLMCASLESYGRYWREV
Mb2643c|M.bovis_AF2122/97           DTGARYFARHGGPEQLRKNLARVLGVPPAAVPDPLMCASLESYGRYWREV
MMAR_2091|M.marinum_M               DAGAHYAARHGGPEQLRKNLARVTGVRAGAVPDSLMRASLESYARYWREA
MUL_3253|M.ulcerans_Agy99           DAGAHYAARHGGPEQLRKNLARVTGVRAGAVPDSLIRASLESYARYWREA
MLBr_00453|M.leprae_Br4923          NTGARYAARNGGPDQLRKNLARIIGVQAADVPDALIRTSLASYARYWREA
MAV_3487|M.avium_104                DAAARYAARGGGPDQLRKNLARVLRVPPADVPDALMRASLASYARYWREA
Mflv_3835|M.gilvum_PYR-GCK          EAGAVWASRNGGPDQLRRNLARVIGSAPAEVPDSLMRASLASYARYWREA
Mvan_2561|M.vanbaalenii_PYR-1       GAGARWAALNGGPEQLRKNLARVIGTTPERVPPALMQASLASYARYWREA
TH_1810|M.thermoresistible__bu      EAGARWAARDGGPDQLRRNLARVLGVAPEQVPDDLIRASLSSYARYWREA
MSMEG_2934|M.smegmatis_MC2_155      GAGARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREA
MAB_2895c|M.abscessus_ATCC_199      DVGAMAGARKGGPEQLRKNLARVLDVHPREVPDRLIIDSMRSYARYWREA
                                     ..*   :  ***:***:****:    .  **  *:  *: **.*****.

Rv2611c|M.tuberculosis_H37Rv        FRLPTINHRKLARQLDRVIGGLDHLDAALAAGLGAVLALPHSGNWDMAGM
Mb2643c|M.bovis_AF2122/97           FRLPTMNHRKLARQLDRVIGGLDHLDAALAAGLGAVLALPHSGNWDMAGM
MMAR_2091|M.marinum_M               FRLPSMNLRKVAAQIDSSIGGKDHLNAGLAAGRGVVLALPHSGNWDMAGV
MUL_3253|M.ulcerans_Agy99           FRLPSMNLRKVAAQIDSSIGGKDHLNAGLAAGRGVVLALPHSGNWDMAGV
MLBr_00453|M.leprae_Br4923          FRLPTMNPHTVAKQVEAYGIDLHRVGEALDAGRGVVLALPHSGNWDMAGV
MAV_3487|M.avium_104                FRLPSMDLTELGRRLQDSVRGEDNLDAALRAGRGAVIALPHSGNWDMAGV
Mflv_3835|M.gilvum_PYR-GCK          FRLPSMDHAELGRKLW--VRDIETVFAALEHGRGAVLALPHSGNWDMAGV
Mvan_2561|M.vanbaalenii_PYR-1       FRLPSMDHEELGRRLH--VRDIERVWAALEAGRGAVLALPHSGNWDMAGV
TH_1810|M.thermoresistible__bu      FRLPTMDHRALGRQLT--VNDIDYLWAALDAGRGAVIALPHSGNWDMAGV
MSMEG_2934|M.smegmatis_MC2_155      FRLPAMDHGRLGEQLD--VIDIDHLWSALDAGRGAVLALPHSGNWDMAGV
MAB_2895c|M.abscessus_ATCC_199      FRLPSQNMERLAARLDSCLYGRRNLDASQAEGRGTVIALPHSGNWDMAGV
                                    ****: :   :. ::     .   :  .   * *.*:************:

Rv2611c|M.tuberculosis_H37Rv        WLVQRHGTFTTVAERLKPESLYQRFIDYRESLGFEVLPLSG----GERPP
Mb2643c|M.bovis_AF2122/97           WLVQRHGTFTTVAERLKPESLYQRFIDYRESLGFEVLPLSG----GERPP
MMAR_2091|M.marinum_M               WLAQRHGTFTTVAERLKPESLYRRFIDYRETLGFEVLPLSG----GAEPP
MUL_3253|M.ulcerans_Agy99           WLAQRHGTFTTVAERLKPESSYRRFIDYRETLGFEVLPLSG----GAEPP
MLBr_00453|M.leprae_Br4923          WLVQCHGTFTTVAERLKPESLYRRFINYRENLGFEVLPMSANKDTGFQAL
MAV_3487|M.avium_104                WLAQSHGTFTTVAERLKPESLYRRFIAYRERLGFEVLPLSG----GERPP
Mflv_3835|M.gilvum_PYR-GCK          WLAQNHGTFATVAERLKPESLYNRFLAYRQSLGFNVVPSSG----GERPA
Mvan_2561|M.vanbaalenii_PYR-1       WLVQNHGTFATVAERLKPESLYNRFLAYRESLGFEVVPLSG----GERPP
TH_1810|M.thermoresistible__bu      WLVQNHGPFTTVAERLRPESLANRFIAYRESLGFEVLPHTG----GDRPP
MSMEG_2934|M.smegmatis_MC2_155      WLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTG----GERPP
MAB_2895c|M.abscessus_ATCC_199      WLAQTYGTFTTVAERLKPESLYRRFLDYRETLGFEVLALTG----DASGP
                                    **.* :*.*:******:***  .**: **: ***:*:. :.    .    

Rv2611c|M.tuberculosis_H37Rv        FEVLSERLRNNRVVCLMAERDLTRTGVEVDFFGEPTRMPVGPAKLAVETG
Mb2643c|M.bovis_AF2122/97           FEVLCERLRNNRVVCLMAERDLTRTGVEVDFFGEPTRMPVGPAKLAVETG
MMAR_2091|M.marinum_M               FEVLCERLRDNRVVCLMAERDLTRTGVEVDFFGEPTRMPAGPAKLAIQTG
MUL_3253|M.ulcerans_Agy99           FEVLCERLRDNRVVCLMAERDLTRTGVEVDFFGEPTRMPAGPAKLAIQTG
MLBr_00453|M.leprae_Br4923          FELLCERLRSNRVVCLMAERDLTRTGVEVDFFGEPTRMPAGPAKLAIKTG
MAV_3487|M.avium_104                FEVLCDRLRDNRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAKLAIATG
Mflv_3835|M.gilvum_PYR-GCK          YDVVRDWLLDNGIVCLMADRDLSRRGVEVDFFGELSRLPAGPAKLAIETG
Mvan_2561|M.vanbaalenii_PYR-1       FEVLRDRLLANGVVCLMADRDMTRTGVQVDFFGEPSRLPAGPAKLALETG
TH_1810|M.thermoresistible__bu      FEVLCERLRANRVVCLMADRDLTRSGVQVDFFGELTRMPAGPARLALETG
MSMEG_2934|M.smegmatis_MC2_155      FEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETG
MAB_2895c|M.abscessus_ATCC_199      YELLAQRLRENRVVCLMADRDLSRSGVPVDFFGAEARMPAGPARLAIDTG
                                    :::: : *  *  :****:**::* ** *****  :*:*.***:**: **

Rv2611c|M.tuberculosis_H37Rv        AALLPTHCWFEGRG-WGFQVYPALDCTSGDVAAITQALADRFAQNIAAHP
Mb2643c|M.bovis_AF2122/97           AALLPTHCWFEGRG-WGFQVYPALDCTSGDVAAITQALADRFAQNIAAHP
MMAR_2091|M.marinum_M               AALLPTHCWFEPKG-WGFQVYPALDCSSGDVEAITQALADRFAANIADHP
MUL_3253|M.ulcerans_Agy99           AALLPTHCWFEPKG-WGFQVYPALDCSSGDVEAITQALADRFAANIADHP
MLBr_00453|M.leprae_Br4923          AALLPVHCWFQGSG-WGFSVHPALDCTSGDVGDVTQALADQFAQDIAANP
MAV_3487|M.avium_104                AALLPVHVHFEGEG-WRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHP
Mflv_3835|M.gilvum_PYR-GCK          APLFPAHCWFDGDG-WGCAVYEPIDTSSSDVSAVTQALADRFAANIAAHP
Mvan_2561|M.vanbaalenii_PYR-1       AALLPVHCWFEPDG-WGMQVYPELDTSSGDVTVITQAMADRFAVNIAAHP
TH_1810|M.thermoresistible__bu      AVLLPAHLWFEPDG-WGMQVYPPIDVSSGDVGVITQALADVFAANIAAHP
MSMEG_2934|M.smegmatis_MC2_155      AALFPVHCWFEGDG-WGMRVYPELDTSSGDVTAITQALADRFAANIATYP
MAB_2895c|M.abscessus_ATCC_199      ARLLPAHCWFEPHERWGVRIHQAVDTSAGDVAVATQAMADVFAANIAERP
                                    * *:*.*  *:    *   ::  :* ::.**   **.:** *  :**  *

Rv2611c|M.tuberculosis_H37Rv        ADWHMLQPQWLADLSESRRAQLRSR------------------
Mb2643c|M.bovis_AF2122/97           ADWHMLQPQWLADLSESRRAQLRSR------------------
MMAR_2091|M.marinum_M               EDWHMFQPQWLADLSDARRARLREP------------------
MUL_3253|M.ulcerans_Agy99           EDWHMFQPQWLADLSDARRARLREP------------------
MLBr_00453|M.leprae_Br4923          TDWHMLQPQWLADLSDAKRAQLRPN------------------
MAV_3487|M.avium_104                EDWHMMQPQWLADLPDSTRARLRDS------------------
Mflv_3835|M.gilvum_PYR-GCK          EDWHMMQPQWVADLSDERRAHLEGT------------------
Mvan_2561|M.vanbaalenii_PYR-1       EDWHMMQPQWVADLSEERRARLEAL------------------
TH_1810|M.thermoresistible__bu      ADWHMLQPQWLADLPEQRRRKLEAS------------------
MSMEG_2934|M.smegmatis_MC2_155      ADWHMLQPQWIADLSDERRARLGT-------------------
MAB_2895c|M.abscessus_ATCC_199      ADWHMLQPLWLDDLSEERRSKLRTAPPQEPAASRETDPVGGQA
                                     ****:** *: **.:  * :*