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ASKAKTGRDDEATSAVELTEATESAVARTDGDSTTDTASKLGHHSFLSRLYTGTGAFEVVGRRRLWFGVS GAIVAVAIASIVFRGFTFGIDFKGGTTVSFPRGSTQVAQVEDVYYRALGSEPQSVVIVGAGASATVQIRS ETLTSDQTAKLRDALFEAFGPKGTDGQPSKQAISDSAVSETWGGQITKKAVIALVVFLVLVALYITVRYE RYMTISAITAMLFDLTVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHTTRRTF AEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTLKDLALVQLIGIIIGTYSSIFFATPLLVT LRERTELVRNHTRRVLKRRNSGSPAGSEDASTDGGEQPAAADEQSLVGITQASSQSAPRAAQGSSKPAPG ARPVRPVGTRRPTGKRNAGRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2586c | secF | - | 100% (442) | preprotein translocase subunit SecF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2617c | secF | 0.0 | 99.55% (442) | preprotein translocase subunit SecF |
| M. gilvum PYR-GCK | Mflv_3815 | secF | 1e-148 | 64.17% (427) | preprotein translocase subunit SecF |
| M. leprae Br4923 | MLBr_00488 | secF | 1e-173 | 72.15% (456) | preprotein translocase subunit SecF |
| M. abscessus ATCC 19977 | MAB_2879c | secF | 1e-141 | 60.23% (435) | preprotein translocase subunit SecF |
| M. marinum M | MMAR_2121 | secF | 0.0 | 74.55% (448) | protein-export membrane protein SecF |
| M. avium 104 | MAV_3467 | secF | 1e-178 | 75.12% (434) | preprotein translocase subunit SecF |
| M. smegmatis MC2 155 | MSMEG_2962 | secF | 1e-156 | 66.14% (443) | preprotein translocase subunit SecF |
| M. thermoresistible (build 8) | TH_1362 | secF | 1e-137 | 72.14% (341) | PROBABLE PROTEIN-EXPORT MEMBRANE PROTEIN SECF |
| M. ulcerans Agy99 | MUL_1726 | secF | 0.0 | 74.55% (448) | preprotein translocase subunit SecF |
| M. vanbaalenii PYR-1 | Mvan_2584 | secF | 1e-150 | 64.75% (434) | preprotein translocase subunit SecF |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3815|M.gilvum_PYR-GCK MATGNR-----------------TDV-ESGAVEAADLEAASINA------
Mvan_2584|M.vanbaalenii_PYR-1 MATRNR-----------------TDADETAAVEAADLESAAAGA------
TH_1362|M.thermoresistible__bu MAAEHS-----------------DTTTESTAVEAPALDTAAP--------
MSMEG_2962|M.smegmatis_MC2_155 MAAKQTK----------------DDDTTSTAVEATPIETSADSAA-----
Rv2586c|M.tuberculosis_H37Rv MASKAKTG---------------RDDEATSAVELTEATESAVARTDGDST
Mb2617c|M.bovis_AF2122/97 MASKAKTG---------------RDDEATSAVELTEATESAVARTDGDST
MLBr_00488|M.leprae_Br4923 MVSRAKVGAETTKGIDEPDRNDNTDDNGAGAVEVTEAAEDAVELTNDIST
MMAR_2121|M.marinum_M MASETKAETTAK-----------NDKKGASAVELTEASEGSAELSGSGSE
MUL_1726|M.ulcerans_Agy99 MASETKAETTAK-----------NDKKGASAVELTEASEGSAELSGSGSE
MAV_3467|M.avium_104 MTSSKAS------------------KAAKGATEITETSSGASELTDSDAA
MAB_2879c|M.abscessus_ATCC_199 MSTSNGTVSNG------------NGTDKDVAEDATDATASTAQEPKSTAV
* : * : . :
Mflv_3815|M.gilvum_PYR-GCK ---------PKHGFFVRLYTGTGAFEVVGKRKLWYTVSALIVAVSIGAMI
Mvan_2584|M.vanbaalenii_PYR-1 ---------PKHGFFVRLYTGTGAFEVMGKRKLWYTVSAVIILVSLGAML
TH_1362|M.thermoresistible__bu ---------KQHGFFVRLYTGTGAFEVVGKRRLWFIVSGLILAVAVASIV
MSMEG_2962|M.smegmatis_MC2_155 --------LPKHGFFVRLYTGTGAFEVIGKRKLWYAVSGIIVVISLASIL
Rv2586c|M.tuberculosis_H37Rv TDTAS--KLGHHSFLSRLYTGTGAFEVVGRRRLWFGVSGAIVAVAIASIV
Mb2617c|M.bovis_AF2122/97 TDTAS--KLGHHSFLSRLYTGTGAFEVVGRRRLWFGVSGAIVAVAIASIV
MLBr_00488|M.leprae_Br4923 QLPQHGFLARFYTGLSRLYTGTGVFEVVGRRRLWYSVGGVIVAVAVLSII
MMAR_2121|M.marinum_M KATGLP----HHNLLSRLYTGTGAFEVVGRRKLWYGISGAIMAIAILSII
MUL_1726|M.ulcerans_Agy99 KATGLP----HHNLLSRLYTGTGAFEVVGRRKLWYGISGAIMAIAILSII
MAV_3467|M.avium_104 AAGLPR-----HSFLSRLYTGTGAFEVVGRRRLWFGISGAIVAVAILSIA
MAB_2879c|M.abscessus_ATCC_199 ETVSAA---PEHGFLYRLYTGTGAVDVVGKRTLWFGISGAFMVVAILSIA
: : *******..:*:*:* **: :.. :: ::: ::
Mflv_3815|M.gilvum_PYR-GCK LRGFTFGIDFEGGTKVSFPRS-----DTQATTQQVETVFNDTIGSPPEAV
Mvan_2584|M.vanbaalenii_PYR-1 LRGFTFGIDFEGGTKVSLPRS-----DAQATTSQVETVFTDTIGTPPEAV
TH_1362|M.thermoresistible__bu LRGFTLGIDFEGGTTVSMPATG---ADGPVAVEEVESIFTDVIGTPPESV
MSMEG_2962|M.smegmatis_MC2_155 LRGFTFGIDFEGGTKVSLPAAG---AQGTITVQQVEDVFNQTLGRSPESV
Rv2586c|M.tuberculosis_H37Rv FRGFTFGIDFKGGTTVSFPR-------GSTQVAQVEDVYYRALGSEPQSV
Mb2617c|M.bovis_AF2122/97 FRGFTFGIDFKGGTTVSFPR-------GSTQVAQVEDVYYRALGSEPQSV
MLBr_00488|M.leprae_Br4923 VRGFTFGIDFKGGTTVSMPVSPGVGGTGAIEVAQVADVFKKTLGSDPESV
MMAR_2121|M.marinum_M VRGFTFGIDFKGGTTVSFPR-------GDSQVTQVEEVFHNVVGSDPESV
MUL_1726|M.ulcerans_Agy99 VRGFTFGIDFKGGTTVSFPR-------GDSQVTQVEEVFHNVVGSDPESV
MAV_3467|M.avium_104 LRGFTFGIDFNGGTTVSMPAAG---THGTVHTAQVQEVFRKTLGTDPESV
MAB_2879c|M.abscessus_ATCC_199 IKGFVFGIDFEGGTKVWFPK-------GDATVQQTEDVFSQTLGHDAESI
.:**.:****:***.* :* . :. :: .:* .:::
Mflv_3815|M.gilvum_PYR-GCK VIVGSGDSATFQIRSETLTNDEIIELRTALFDAFQPVGPDGQPSEQAVSD
Mvan_2584|M.vanbaalenii_PYR-1 VVVGSGDSATFQIRSETLDNDQIVELRKALFDAFQPKGADGQPSEQAVSD
TH_1362|M.thermoresistible__bu VVVGSGSTATVQIRSETLTNDETEDLRTALFDRFQPATPDGTPSRAAISD
MSMEG_2962|M.smegmatis_MC2_155 VTVGSGGSATLQIRAETLTNEETEELRNALFDTLQPKGADGQPSKQVISD
Rv2586c|M.tuberculosis_H37Rv VIVGAGASATVQIRSETLTSDQTAKLRDALFEAFGPKGTDGQPSKQAISD
Mb2617c|M.bovis_AF2122/97 VIVGAGASATVQIRSETLTSDQTAKLRDALFEAFGPKGTDGQPSKQAISD
MLBr_00488|M.leprae_Br4923 VVVGNGASATVRISSKTLSNDQTSKLRNALFDAFGPKGADAKPSKQAISD
MMAR_2121|M.marinum_M VTVGSGASATVQIRSETLSNEQTEKLRDALFDAFHPKGADGKPSKKAISD
MUL_1726|M.ulcerans_Agy99 VTVGSGASATVQIRSETLSNEQTEKLRDALFDAFHPKGADGKPSKKAISD
MAV_3467|M.avium_104 VVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPKGADGKPSKQAISD
MAB_2879c|M.abscessus_ATCC_199 VVTGTGDSASIQIRTEKLDNEQSSKLHKALFDRFAPKGPDGKPSIDAISD
* .* * :*:.:* ::.* .:: .*: ***: : * .*. ** .:**
Mflv_3815|M.gilvum_PYR-GCK SAVSETWGGQITQKALIALVVFLILAAIYITVRYEWSMALAALATLVFDL
Mvan_2584|M.vanbaalenii_PYR-1 SAVSETWGGQITQKALIALAVFLVLAAIYITVRYERYMAIAALATLVFDL
TH_1362|M.thermoresistible__bu SAVSETWGDQITKKAIIALVVFVVLAAIYITARYERYMALSALAAMFFDI
MSMEG_2962|M.smegmatis_MC2_155 SAVSETWGGQITKKMVIALVVFLVLAAIYITWRYERYMAISALATMVFDI
Rv2586c|M.tuberculosis_H37Rv SAVSETWGGQITKKAVIALVVFLVLVALYITVRYERYMTISAITAMLFDL
Mb2617c|M.bovis_AF2122/97 SAVSETWGGQITKKAVIALVVFLVLVALYITVRYERYMTISAITAMLFDL
MLBr_00488|M.leprae_Br4923 AAVSETWGGQITKKVVIALVVFLVLVGLYITVRYERYMAISALTTMCFDL
MMAR_2121|M.marinum_M AAVSETWGGQITKKAVIALVVFLVLVAIYITVRYERYMTISAIAAMIFDL
MUL_1726|M.ulcerans_Agy99 AAVSETWGGQITKKAVIALVVFLVLVAIYITVRYERYMTISAIAAMIFDL
MAV_3467|M.avium_104 SAVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDL
MAB_2879c|M.abscessus_ATCC_199 SDVSETWGSQITNKALWALGVFLVLAGIYIAVRYERYMSLAALAALVFDL
: ******.***.* : ** **: *..:**: *** *:::*:::: **:
Mflv_3815|M.gilvum_PYR-GCK VVTAGVYALVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTDGFEHT
Mvan_2584|M.vanbaalenii_PYR-1 LVTAGVYALVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTDGFEHT
TH_1362|M.thermoresistible__bu IVTAGIYSLVGWEVTPAMVIGLMTILGFSIYDTVIVFDKVEENTHGFEHT
MSMEG_2962|M.smegmatis_MC2_155 VVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFEHT
Rv2586c|M.tuberculosis_H37Rv TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
Mb2617c|M.bovis_AF2122/97 TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
MLBr_00488|M.leprae_Br4923 TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
MMAR_2121|M.marinum_M TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
MUL_1726|M.ulcerans_Agy99 TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
MAV_3467|M.avium_104 TVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHT
MAB_2879c|M.abscessus_ATCC_199 LVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHT
****:*:***:***** ****:******:************** .*:**
Mflv_3815|M.gilvum_PYR-GCK TRRTYAEQANLAVNQTFMRSINTSVISVLPIIALMVIAVWLLGVGTLMDL
Mvan_2584|M.vanbaalenii_PYR-1 TRRTFAEQANLAVNQTFMRSINTSLISVLPIIALMVIAVWLLGVGTLMDL
TH_1362|M.thermoresistible__bu TRRTYAEQANLAVNQTFMRSINTSLISVLPIVALMIIAVWMLGVGTLKDL
MSMEG_2962|M.smegmatis_MC2_155 TRRTFAEQANLAVNQTFMRSINTSLISVLPIVALMVVAVWLLGVGTLMDL
Rv2586c|M.tuberculosis_H37Rv TRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTLKDL
Mb2617c|M.bovis_AF2122/97 TRRTFAEQANLAINQTFMRSINTSLIGVLPVLTLMVVAVWLLGVGTLKDL
MLBr_00488|M.leprae_Br4923 TRRTFAEQANLAINQTFMRSINTSLISVLPVLALMVVAVWLLGVGTLKDL
MMAR_2121|M.marinum_M TRRTFAEQANLAVNQTFMRSINTSLISVLPVLSLMVVAVWLLGVGTLKDL
MUL_1726|M.ulcerans_Agy99 TRRTFAEQANLAVNQTFMRSINTSLISVLPVLSLMVVAVWLLGVGTLKDL
MAV_3467|M.avium_104 NRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTLKDL
MAB_2879c|M.abscessus_ATCC_199 SRRTYAEHANLAVNQTFMRSINTSLISAIPVLSLIVVAIWLLGVGTLKDL
.***:**:****:***********:*..:*:::*:::*:*:****** **
Mflv_3815|M.gilvum_PYR-GCK ALVQLVGVIVGTYSSIYFATPLLVSLRER-TEAVRKHNRRVHNRRQTAAA
Mvan_2584|M.vanbaalenii_PYR-1 ALVQLVGVIVGTYSSIFFATPLLVSLRER-TELVSKHTRRVLNRRKTAAA
TH_1362|M.thermoresistible__bu ALVQLVGVIVGTYSSIYFATPLLVSLRERFDDKVRKHTRRVLNRXXSPPT
MSMEG_2962|M.smegmatis_MC2_155 ALVQLVGVIVGTYSSIYFATPLLVSLRER-TELVRKHTQKVLNRRQAGKG
Rv2586c|M.tuberculosis_H37Rv ALVQLIGIIIGTYSSIFFATPLLVTLRER-TELVRNHTRRVLKRRNSGSP
Mb2617c|M.bovis_AF2122/97 ALVQLIGIIIGTYSSIFFATPLLVTLRER-TELVRNHTRRVLKRRNSGSP
MLBr_00488|M.leprae_Br4923 ALVQLVGIIVGTYSSIFFATPLLVTLRER-TELVRTHTRRVVKRRTLGSQ
MMAR_2121|M.marinum_M ALVQLIGIIVGTYSSIFFATPLLVTLRER-TELVRSHTRKVIKRRTPASR
MUL_1726|M.ulcerans_Agy99 ALVQLIGIIVGTYSSIFFATPLLVTLRER-TELVRSHTRKVIKRRTPASR
MAV_3467|M.avium_104 ALVQLVGILVGTYSSIFVATPLLVTLRER-TELVRTHTRRVLKRRAGGAR
MAB_2879c|M.abscessus_ATCC_199 ALVQLVGILVGTYSSIFFATPLLVALRER-TDLVASHTKKVLSRRKPDAA
*****:*:::******:.******:**** : * .*.::* .*
Mflv_3815|M.gilvum_PYR-GCK KAAGVEVDDEISESATKSEAVAAAVAAQTAPAD-------------KPAP
Mvan_2584|M.vanbaalenii_PYR-1 RAGGVEISDDDTAVDGDAEPATVAATPPAPLPD-------------KPVP
TH_1362|M.thermoresistible__bu TAR---------------------------RRS-------------RPAP
MSMEG_2962|M.smegmatis_MC2_155 AVKTAADDASEEADGGD-----TVTASSTPAAA-------------KPAP
Rv2586c|M.tuberculosis_H37Rv AGSEDASTDGGEQPAAADEQSLVGITQASSQSAPRAAQGS-----SKPAP
Mb2617c|M.bovis_AF2122/97 AGSEDASTDGGEQPAAADEQSLVGITQASSQSAPRAAQGS-----SKPAP
MLBr_00488|M.leprae_Br4923 VGKKNADSHVAAGTRKPQNQAES-CADASSQEGTEVATASVPTVLSKLAP
MMAR_2121|M.marinum_M AAGERAEADAESGQELTETTAAETSTETARPNEKADAKPAAS---NKPAP
MUL_1726|M.ulcerans_Agy99 AAGERAEADAESGQELTETTAAETSTETARPNEKADAKPAAS---NKPAP
MAV_3467|M.avium_104 ASAESTADDAAETPAGSGD----EATEAERESPSSRAAPS------KPAP
MAB_2879c|M.abscessus_ATCC_199 PLADAGVGSKTAKVATSGTSD-------------------------AAAT
..
Mflv_3815|M.gilvum_PYR-GCK GARPVRPTSSRTGRPSGKRTPRNR-
Mvan_2584|M.vanbaalenii_PYR-1 GARPVRPTSSRTGRPSGKRTPRNR-
TH_1362|M.thermoresistible__bu GWSTWSRNACRCGSTSSSPTAPMSG
MSMEG_2962|M.smegmatis_MC2_155 GARPARPSGARTGRPSGKRTNRR--
Rv2586c|M.tuberculosis_H37Rv GARPVRPVGTR--RPTGKRN-AGRR
Mb2617c|M.bovis_AF2122/97 GARPVRPVGTR--RPPGKRN-AGRR
MLBr_00488|M.leprae_Br4923 GVRPVRPTGTR--RPTGKRNNVGRR
MMAR_2121|M.marinum_M GARPVRPTATK--RPTGKRN-AGRR
MUL_1726|M.ulcerans_Agy99 GARPVRPTATK--RPTGKRN-AGRR
MAV_3467|M.avium_104 GARPVRPTGAR--RPTGKRN-VGRR
MAB_2879c|M.abscessus_ATCC_199 GVRPAKPKPGA--RPQGKRNTRRH-
* . . .. .