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M. tuberculosis H37Rv Rv2577 (-)

annotation: hypothetical protein Rv2577
coordinates: 2900918 - 2902507
length: 529

VGADLKQPQDADSPPKGVSRRRFLTTGAAAVVGTGVGAGGTALLSSHPRGPAVWYQRGRSGAPPVGGLHL
QFGRNASTEMVVSWHTTDTVGNPRVMLGTPTSGFGSVVVAETRSYRDAKSNTEVRVNHAHLTNLTPDTDY
VYAAVHDGTTPELGTARTAPSGRKPLRFTSFGDQSTPALGRLADGRYVSDNIGSPFAGDITIAIERIAPL
FNLINGDLCYANLAQDRIRTWSDWFDNNTRSARYRPWMPAAGNHENEVGNGPIGYDAYQTYFAVPDSGSS
PQLRGLWYSFTAGSVRVISLHNDDVCYQDGGNSYVRGYSGGEQRRWLQAELANARRDSEIDWVVVCMHQT
AISTADDNNGADLGIRQEWLPLFDQYQVDLVVCGHEHHYERSHPLRGALGTDTRTPIPVDTRSDLIDSTR
GTVHLVIGGGGTSKPTNALLFPQPRCQVITGVGDFDPAIRRKPSIFVLEDAPWSAFRDRDNPYGFVAFDV
DPGQPGGTTSIKATYYAVTGPFGGLTVIDQFTLTKPRGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2577--100% (529)hypothetical protein Rv2577

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2608-0.0100.00% (434) hypothetical protein Mb2608
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1951c-6e-4029.64% (533) hypothetical protein MAB_1951c
M. marinum MMMAR_2149-0.077.95% (526) hypothetical protein MMAR_2149
M. avium 104MAV_3455-0.076.34% (524) metallophosphoesterase
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv2577|M.tuberculosis_H37Rv         ----------MGADLKQP-QDADSPPKGVSRRRFLTTGAA-AVVGTGVGA
Mb2608|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2149|M.marinum_M               ----------MPDDLDQP-DDPQ--PVGPSRRKLLTTGLASAAVGAGIGL
MAV_3455|M.avium_104                ----------MSDEPTQPPNPAGAAAPGVTRRRLLTTGAVSAALGVGIGG
MAB_1951c|M.abscessus_ATCC_199      MSRNPLNPAGETPDMGIPQSIAGSMSMAEQYEWHRGYLRRHAVSRRNFLR
                                                                                      

Rv2577|M.tuberculosis_H37Rv         GGTALLSS--HPRGPAVWYQRGRSGAPPVGGLHLQFGRNASTEMVVSWHT
Mb2608|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2149|M.marinum_M               GGAALLR---PGRGPSVWYQPDRTSAQPVGGLHLQYGKNAATEVVVSWHS
MAV_3455|M.avium_104                GATLLWSQSARSRGPWPWLQPDRNGAPPVAGLHLQFGKNAGTEVVVSWHS
MAB_1951c|M.abscessus_ATCC_199      GSAAAAAVAALGVSPFGRRAYADEAQLGVAGRRVGYGADSSSQLSFSAQL
                                                                                      

Rv2577|M.tuberculosis_H37Rv         TDTVGNPRVMLGT-PTSGFGSVVVAETRSYRDAKSN-------TEVRVNH
Mb2608|M.bovis_AF2122/97            ---------MLGT-PTSGFGSVVVAETRSYRDAKSN-------TEVRVNH
MMAR_2149|M.marinum_M               VDAVQNPRVMLGT-PASGFGRVVSAETRTYRDAKSN-------TEVRVNH
MAV_3455|M.avium_104                TDAVRNPRVVFGT-PVSGFGRTVAADTRTYRDAKSG-------IEVRVNH
MAB_1951c|M.abscessus_ATCC_199      SRNPHGTKIFLDHGPTPELGASLEAEVRNLVTQIPSSDHGVLAAEQFYVH
                                             .:.  *.. :*  : *:.*.     ..        *    *

Rv2577|M.tuberculosis_H37Rv         AHLTNLTPDTDYVY-AAVHDGTTPELGTARTAPSGRK----PLRFTSFGD
Mb2608|M.bovis_AF2122/97            AHLTNLTPDTDYVY-AAVHDGTTPELGTARTAPSGRK----PLRFTSFGD
MMAR_2149|M.marinum_M               ARLTNLTPDSDYVY-AAVHDGADPQLGTVRTAPLGRK----PLRFTSFGD
MAV_3455|M.avium_104                ARLTGLTPDTDYVY-AALHDGAQPQQGTVRTAPMGRK----PLRFTSFGD
MAB_1951c|M.abscessus_ATCC_199      APVHGLPGGTGHFYRWRTADGFLSDIRSAATAVPAARNALAPFRFTMMGD
                                    * : .*. .:.:.*     **  .:  :. **  . :    *:*** :**

Rv2577|M.tuberculosis_H37Rv         Q---STPALG-RLADGRYVSDNIGS------PFAGDITIAIERIAPLFNL
Mb2608|M.bovis_AF2122/97            Q---STPALG-RLADGRYVSDNIGS------PFAGDITIAIERIAPLFNL
MMAR_2149|M.marinum_M               Q---GTPTLG-RFSDGRYVSDNGGT------PAAGDITIAIEHMAPLFNL
MAV_3455|M.avium_104                Q---STPALA-KMPNGRYATDNIGS------PAAADTTMAIERIGPLFNL
MAB_1951c|M.abscessus_ATCC_199      QGTDETPALPPNLAAGEYDDNYYGADNDPAVPHTQNVMNQIVASRPDFHI
                                    *    **:*  .:. *.*  :  *:      * : :    *    * *::

Rv2577|M.tuberculosis_H37Rv         INGDLCYAN-------------------LAQDRIRTWSDWFDNNTRSARY
Mb2608|M.bovis_AF2122/97            INGDLCYAN-------------------LAQDRIRTWSDWFDNNTRSARY
MMAR_2149|M.marinum_M               VNGDLCYAN-------------------MAHDRIRTWSDWLETNGRSARY
MAV_3455|M.avium_104                VNGDLCYAN-------------------LAQNRIRTWSDWFENNSRSARF
MAB_1951c|M.abscessus_ATCC_199      LAGDIAYADPSGMGKSPQFVSGAKAPSGFDKYNPFVWDVYLTSIEPSAST
                                    : **:.**:                   : : .  .*. :: .   **  

Rv2577|M.tuberculosis_H37Rv         RPWMPAAGNHENEVGNGPIGYDAYQTYFAVPDSGSSPQLRGLWYSFTAGS
Mb2608|M.bovis_AF2122/97            RPWMPAAGNHENEVGNGPIGYDAYQTYFAVPDSGSSPQLRGLWYSFTAGS
MMAR_2149|M.marinum_M               RPWMPAAGNHENELGNGPIGYGAYQTYFSVPDSGASQELRGLWYSFTAGS
MAV_3455|M.avium_104                RPWMPAAGNHENELGNGPIGYGAYQAYFAVPDSGSSPETRGLWYSFTAGS
MAB_1951c|M.abscessus_ATCC_199      TPWMFATGNHDMEAAYGNHGYGGHLARLGFPGNGPTGCPS--AYSFTYGN
                                     *** *:***: * . *  **..: : :..*..*.:       **** *.

Rv2577|M.tuberculosis_H37Rv         VRVISLHNDDVCYQDGGNSYVRGYSGGEQRRWLQAELANARRDSEIDWVV
Mb2608|M.bovis_AF2122/97            VRVISLHNDDVCYQDGGNSYVRGYSGGEQRRWLQAELANARRDSEIDWVV
MMAR_2149|M.marinum_M               VRVISLSNDDVCFQDAGSSYVHGYSGGEQRRWLQTELAAARRDPAVDWVI
MAV_3455|M.avium_104                VRVVSLSNDDVAFQDGGNFYVHGYSGGEQKRWLATELAAARRDPDVDWLV
MAB_1951c|M.abscessus_ATCC_199      VAVLSLDANDVSYEIRAN---TGYSGGAQTGWVGRTLATYRANPNIDFIV
                                    * *:**  :**.::  ..    ***** *  *:   **  * :. :*:::

Rv2577|M.tuberculosis_H37Rv         VCMHQTAISTADDNNGADLGIRQEWLPLFDQYQVDLVVCGHEHHYERSHP
Mb2608|M.bovis_AF2122/97            VCMHQTAISTADDNNGADLGIRQEWLPLFDQYQVDLVVCGHEHHYERSHP
MMAR_2149|M.marinum_M               VCMHQTAISTADHFNGADLGIRQEWLPLFDQYEVDLVLCGHEHHYERSHP
MAV_3455|M.avium_104                VCMHQTAISTADRTNGADLGIREEWLPLFDQYQVDLVLCGHEHHYERSHP
MAB_1951c|M.abscessus_ATCC_199      CFFHHCAYSTTLS-HASDGGVRDAWCALFDRYQVDLVLQGHNHVFERTDP
                                      :*: * **:   :.:* *:*: * .***:*:****: **:* :**:.*

Rv2577|M.tuberculosis_H37Rv         LRGALGTDTRTPIPVDTRSDLIDSTRGTVHLVIGGGGTSKPTNALLFPQ-
Mb2608|M.bovis_AF2122/97            LRGALGTDTRTPIPVDTRSDLIDSTRGTVHLVIGGGGTSKPTNALLFPQ-
MMAR_2149|M.marinum_M               LRGAMDTQTRTPIPVDTRGDVIDATRGTVHLVIGCGGRSLTSNQLFFPE-
MAV_3455|M.avium_104                LRGALGTDTRTPIPVDTRGDLIDATRGTVHLVIGGGGTSAPSNAMFFPE-
MAB_1951c|M.abscessus_ATCC_199      IRAGQPTREAG-----DNSTVDPETDGTVYYTVGSAGRPRYDFQPGEPEG
                                    :*..  *          .. :   * ***: .:* .* .        *: 

Rv2577|M.tuberculosis_H37Rv         PRCQVITGVGDFDPAIRRKPSIFVLEDAPWSAFRDRDNPYGFVAFDVDPG
Mb2608|M.bovis_AF2122/97            PRCQVITGVGDFDPAIRRKPSIFVLEDAPWSAFRDRDNPYGFVAFDVDPG
MMAR_2149|M.marinum_M               PRCRVVTAVGPYDPGERSRPSIYVLEDAPWSAFRDHDNPYGFAAFDVDPG
MAV_3455|M.avium_104                PRCRVLTGVGTFDPGLGRKAPIYVIEDAPWSAFRDRDNPYGFVAFDVDPG
MAB_1951c|M.abscessus_ATCC_199      YRGRELSDTLVPNSFVWASDGSKHAEAVAWSRVRYRN--YAFIRVDVRPG
                                     * : :: .   :.           * ..** .* ::  *.*  .** **

Rv2577|M.tuberculosis_H37Rv         QPGGTTSIKATYYAVTGPFGGLTVIDQFTLTKPRGG---
Mb2608|M.bovis_AF2122/97            QPGGTTSIKATYYAVTGPFGGLTVIDQFTLTKPRGG---
MMAR_2149|M.marinum_M               QPGGHTSIKATHYAVTGLFGATTVVDEFTLTKPRGD---
MAV_3455|M.avium_104                PAGGNTSIRATHYALTGPLGEMSVIDRFTLTKPRGDGAR
MAB_1951c|M.abscessus_ATCC_199      ALVSEMDVTAVDEYGR-EFDKVTYRRRVHAAVR------
                                       .  .: *.       :.  :   ..  :