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M. tuberculosis H37Rv Rv2537c (aroD)

annotation: 3-dehydroquinate dehydratase
coordinates: 2861148 - 2861591
length: 147

SELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAE
PVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYL
AEHVGT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2537caroD-100% (147)3-dehydroquinate dehydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2566caroD8e-80100.00% (147) 3-dehydroquinate dehydratase
M. gilvum PYR-GCKMflv_4683-1e-3146.04% (139) 3-dehydroquinate dehydratase, type II
M. leprae Br4923MLBr_00519aroD1e-6785.92% (142) 3-dehydroquinate dehydratase
M. abscessus ATCC 19977MAB_2840c-5e-5777.37% (137) 3-dehydroquinate dehydratase
M. marinum MMMAR_2178aroD2e-6889.29% (140) 3-dehydroquinate dehydratase AroD
M. avium 104MAV_3413aroQ1e-6789.21% (139) 3-dehydroquinate dehydratase
M. smegmatis MC2 155MSMEG_1922aroQ6e-2944.20% (138) 3-dehydroquinate dehydratase, type II
M. thermoresistible (build 8)TH_0107aroD2e-6384.67% (137) 3-DEHYDROQUINATE DEHYDRATASE AROD (AROQ) (3-DEHYDROQUINASE)
M. ulcerans Agy99MUL_1762aroD4e-6888.57% (140) 3-dehydroquinate dehydratase
M. vanbaalenii PYR-1Mvan_1784-2e-3247.48% (139) 3-dehydroquinate dehydratase, type II

CLUSTAL 2.0.9 multiple sequence alignment


Rv2537c|M.tuberculosis_H37Rv        --MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKA
Mb2566c|M.bovis_AF2122/97           --MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKA
MLBr_00519|M.leprae_Br4923          ----MTMVNIINGPNLGRLGRREPDVYGSTTHEQLSALIERAAVEFGIKA
MMAR_2178|M.marinum_M               MSEPMTVVNVLNGPNLGRLGRREPDVYGSTTHAELAALIEREAAGLGLQA
MUL_1762|M.ulcerans_Agy99           MSEPMTVVNVLNGPNLGRLGRREPDVYGSTTHAELAALIEREAAGLGLQA
MAV_3413|M.avium_104                -----MIVQVINGPNLGRLGRREPDVYGDTTHDQLAALIEAEAAALGLKA
TH_0107|M.thermoresistible__bu      -MTAQSTVYVINGPNLGRLGRRQPEVYGSTTHDDLVAMIEREATDLGLKA
MAB_2840c|M.abscessus_ATCC_199      -----MTIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDV
Mflv_4683|M.gilvum_PYR-GCK          --MTERRLLLLNGPNLNLLGTRQPEVYGSTTLAEIEAKVAEVAKDAGLQV
Mvan_1784|M.vanbaalenii_PYR-1       --MTERRLLLVNGPNLNLLGTRQPEVYGATTLAEIEARVAEVAAEAGLQV
MSMEG_1922|M.smegmatis_MC2_155      --MTERRLLLVNGPNLNLLGTRQPEIYGSTTLADIEKSVTALAAEFGFEV
                                           : ::*****. ** *:. :** .*  ::   :   *   *...

Rv2537c|M.tuberculosis_H37Rv        VVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPL
Mb2566c|M.bovis_AF2122/97           VVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPL
MLBr_00519|M.leprae_Br4923          VVRQSDSESQLLDWIHLAADAGEPVILNAGGLTHTSVALRDACAELSAPF
MMAR_2178|M.marinum_M               VVRQSDSEAELLDWIHRAADAGQPVILNAGGLTHTSVALRDACAELSAPL
MUL_1762|M.ulcerans_Agy99           VVRQSDSEAELLDWIHRAADAGQPVILNAGGLTHTSVALRDACAELSAPL
MAV_3413|M.avium_104                IVRQSDSEAELLDWIHGAADANQPVILNAGGLTHTSVALRDACAELSAPL
TH_0107|M.thermoresistible__bu      VVRQSDSEAELLGWIHDAADAGVPVILNAGAFTHTSIALRDACAELRAPL
MAB_2840c|M.abscessus_ATCC_199      QVRQSDSEAELLGWVHDAADAKDPVILNAGAFTHTSVALRDACAELSAGL
Mflv_4683|M.gilvum_PYR-GCK          RAVQSNHEGVLVDAIHAARTECVGIIINPAAYSHTSVAIADALRSVGLPV
Mvan_1784|M.vanbaalenii_PYR-1       RSVQSNHEGVLVDAIHAARTDCAGIIINPAAYSHTSVAIADALRSVGLPV
MSMEG_1922|M.smegmatis_MC2_155      RAVQSNHEGALVDAIQAARTDCAGIIINPAAYSHTSVAIADALTSVELPV
                                       **: *. *:. :: *      :*:*... :***:*: **  .:   .

Rv2537c|M.tuberculosis_H37Rv        IEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT-
Mb2566c|M.bovis_AF2122/97           IEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT-
MLBr_00519|M.leprae_Br4923          IEVHISNVHAREEFRRHSYLSPLATGVITGLGVQGYLLALRYLAEIAGN-
MMAR_2178|M.marinum_M               IEVHISNVHAREEFRRHSYLSPVATGVIVGLGIQGYLLALRYLASY----
MUL_1762|M.ulcerans_Agy99           IEVHISNVHAREEFRRHSYLSPVATGVIVGLGIRGYLLALRYLASY----
MAV_3413|M.avium_104                IEVHISNVHAREEFRRHSYLSPVATGVIVGLGVQGYLLALRYLAGRPA--
TH_0107|M.thermoresistible__bu      IEVHISNVHAREEFRHHSYLSAVATGVIVGLGVQGYLLALRYLANTGKSA
MAB_2840c|M.abscessus_ATCC_199      IEVHISNVHAREEFRHHSYLSALATGVIVGLGVQGYLLALRYFVASASS-
Mflv_4683|M.gilvum_PYR-GCK          AEVHLSNIHAREEFRHHSYVSAVADMVVAGAGPLGYEMAVQYLADRLGP-
Mvan_1784|M.vanbaalenii_PYR-1       AEVHLSNIHAREEFRHHSYVSAVADMVVAGAGPLGYEMAVRFLADRLGR-
MSMEG_1922|M.smegmatis_MC2_155      AEVHLSNIHRREEFRHHSYVSAVAEMVICGAGAAGYEYAVRYLVGRV---
                                     ***:**:* *****:***:*.:*  *: * *  **  *::::.