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M. tuberculosis H37Rv Rv2536 (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 2860452 - 2861144
length: 230

MTNWMLRGLAFAAAMVVLRLFQGALINAWQMLSGLISLVLLLLFAIGGVVWGVMDGRADAKASPDPDRRQ
DLAMTWLLAGLVAGALSGAVAWLISLFYKAIYTGGPINELTTFAAFTALIVFLVGIVGVAVGRWLVDRQL
AKAPVRHHGLAAEHERAADTDVFSAVRADDSPTGEMQVAQPEAQTAAVATVEREAPTEVIRTTESDTPTE
VIRTDTEADQTKPGDEPKKD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2536--100% (230)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2565-1e-128100.00% (230) transmembrane protein
M. gilvum PYR-GCKMflv_3754-6e-5553.23% (201) hypothetical protein Mflv_3754
M. leprae Br4923MLBr_00520-9e-6763.18% (201) hypothetical protein MLBr_00520
M. abscessus ATCC 19977MAB_2839-2e-3847.67% (172) hypothetical protein MAB_2839
M. marinum MMMAR_2179-2e-8572.89% (225) transmembrane protein
M. avium 104MAV_3414-2e-7567.25% (229) hypothetical protein MAV_3414
M. smegmatis MC2 155MSMEG_3032-3e-5560.95% (169) hypothetical protein MSMEG_3032
M. thermoresistible (build 8)TH_2662-4e-5557.84% (185) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_1763-1e-8466.54% (254) transmembrane protein
M. vanbaalenii PYR-1Mvan_2649-2e-6157.14% (210) hypothetical protein Mvan_2649

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3754|M.gilvum_PYR-GCK          --------------------MSKWLVRGLVLAALMVIVRLLQGAMINAWE
Mvan_2649|M.vanbaalenii_PYR-1       --------------------MSKWLLRGLVFAALMVIVRLLQGALINAWE
TH_2662|M.thermoresistible__bu      --------------------MSKWLLRGLVFAALMVVVRLFQGALINAWP
MSMEG_3032|M.smegmatis_MC2_155      --------------------MSKWLLRGVVFATAMVIVRLLQGALVNASP
Rv2536|M.tuberculosis_H37Rv         --------------------MTNWMLRGLAFAAAMVVLRLFQGALINAWQ
Mb2565|M.bovis_AF2122/97            --------------------MTNWMLRGLAFAAAMVVLRLFQGALINAWQ
MMAR_2179|M.marinum_M               --------------------MTNWMLRGLAFAAAMVVLRLFQGALINAWQ
MUL_1763|M.ulcerans_Agy99           --------------------MTNWMLRGLAFAAAMVVLRLFQGALINAWQ
MAV_3414|M.avium_104                ------------------------MLRGLVYAAAMVVVRLFQGALINAWQ
MLBr_00520|M.leprae_Br4923          --------------------MNNWMLRGLVFAALMIVVRLMQGTMINVWQ
MAB_2839|M.abscessus_ATCC_1997      MPEAQSAPLRASGSSATRALTTQWLTRGAVFAVLMVLVRVVQGLAISLWE
                                                            : ** . *. *:::*:.**  :.   

Mflv_3754|M.gilvum_PYR-GCK          TKAGLISAVLVAAYAVVALIWGYADGRSDARRNPDPDRRDDLAMSWLLAG
Mvan_2649|M.vanbaalenii_PYR-1       TKAGLISVILVVAYAIVALVWGYVDGRADARDNPDPDRRQDLAMAWLLAG
TH_2662|M.thermoresistible__bu      VRATLISVTLVVAFAIVAFVWGYLDGRSDARANPDPDRRSDLSMAWLLAG
MSMEG_3032|M.smegmatis_MC2_155      GNAIWFSTGLLVLYAIGVAVWGVLDGRGDARSNPDPDRRADLAMTWLLAG
Rv2536|M.tuberculosis_H37Rv         MLSGLISLVLLLLFAIGGVVWGVMDGRADAKASPDPDRRQDLAMTWLLAG
Mb2565|M.bovis_AF2122/97            MLSGLISLVLLLLFAIGGVVWGVMDGRADAKASPDPDRRQDLAMTWLLAG
MMAR_2179|M.marinum_M               TQAGLISLVLLLLYVIAVIVWGTLDGRADAKANPDPDRRADLAMTWLVAG
MUL_1763|M.ulcerans_Agy99           TQAGLISLVLLLLYVIAVIVWGTLDGRADAKANPDPDRRADLAMTWLVAG
MAV_3414|M.avium_104                TQAGLFSVVLLLLFVIAVAVWGVFDGRADAIANPDPDRRGDLAMTWLLAG
MLBr_00520|M.leprae_Br4923          AQSVLISVVLLAVFIIAVVVWAARDGRADAIANPDPDRRRDLAMTWLLTG
MAB_2839|M.abscessus_ATCC_1997      THGTAINIVLVLVFLAAVTAWAVADGRGDAQRNPDPDRREDLAMWWLLGG
                                      .  :.  *:  :      *.  ***.**  .****** **:* **: *

Mflv_3754|M.gilvum_PYR-GCK          LFAGVVSGAVAWFIGLFYKNLYVEGLINELTTFAAFTALLVFISAIIGVA
Mvan_2649|M.vanbaalenii_PYR-1       LFAGVVSGAVAWFIGIFYKNLYVEGLINELTTFAAFTALLVFIAAIIGVA
TH_2662|M.thermoresistible__bu      LFAGVVSGAVCWFIGLFYESLYVEALINEVTTFAAFTALLTFLAALSGVA
MSMEG_3032|M.smegmatis_MC2_155      LAAGILSGAVSWFIGLFYKSIYTESLLNEITTFAAFTALLTFLVAVAGVT
Rv2536|M.tuberculosis_H37Rv         LVAGALSGAVAWLISLFYKAIYTGGPINELTTFAAFTALIVFLVGIVGVA
Mb2565|M.bovis_AF2122/97            LVAGALSGAVAWLISLFYKAIYTGGPINELTTFAAFTALIVFLVGIVGVA
MMAR_2179|M.marinum_M               LVAGILSGAVAWIIALFYKGIYVGGLINEVTTFAAFTALIIFLPGISGVA
MUL_1763|M.ulcerans_Agy99           LVAGILSGAVAWIIALFYKSIYVGGLINEVTTFAAFTALIIFLPGISGVA
MAV_3414|M.avium_104                LVAGVLSGAVSWLIALVYKGLYTGGLINEVTTFAAFTALCVFLPGIIGVT
MLBr_00520|M.leprae_Br4923          ILVGVLSDAVAWVISLLYNGIYTGGLVSELTTFSAFTALIVFLTGIIGVA
MAB_2839|M.abscessus_ATCC_1997      IFAGVVSGLVIWLISLFNDGIYAASILAELTTTAAFVALLVFVPAMAGVF
                                    : .* :*. * *.*.:. . :*. . : *:** :**.**  *: .: ** 

Mflv_3754|M.gilvum_PYR-GCK          LGHWLVDRKAPAQERRRE----DDDR-ADTDVFAAVR-DTGSSEGNSEDY
Mvan_2649|M.vanbaalenii_PYR-1       LGHWLVDRKTPEQPRRREG---DDDR-ADTDVFAAVR-DDSG-------Y
TH_2662|M.thermoresistible__bu      LGRWLVDRKTPDQPRRRVGAD-GDTN-ADTDVFAAVQ-NGGG--------
MSMEG_3032|M.smegmatis_MC2_155      IGRWTIDRKAPPVTRTRHGLAADDDR-ADTDVFAAVS-ANGA--------
Rv2536|M.tuberculosis_H37Rv         VGRWLVDRQLAKAPVRHHGLAAEHERAADTDVFSAVR-ADDSPTGEMQVA
Mb2565|M.bovis_AF2122/97            VGRWLVDRQLAKAPVRHHGLAAEHERAADTDVFSAVR-ADDSPTGEMQVA
MMAR_2179|M.marinum_M               VGRWRVDRNAPPAPT-HDGTGGR----ADTDVFAAVR-ADDSPTGEMPVA
MUL_1763|M.ulcerans_Agy99           VGRWRVDRNAPPVPT-HDGTGGR----ADTDVFAAVR-ADDSPTGEMPVA
MAV_3414|M.avium_104                IGRWRVDRNPPPRRPGHD--DER----ADTDVFSAVR-GDDAPTGEIPAA
MLBr_00520|M.leprae_Br4923          CGRWRVDRRSPPVPEHSRSGQNR----ADSNVFAAVCTDDDTPTGELSAA
MAB_2839|M.abscessus_ATCC_1997      AGRLLVDRKHKEHAALQQ---------SDTDVFQAVQEEADATK------
                                     *:  :**.                  :*::** **    .         

Mflv_3754|M.gilvum_PYR-GCK          DRYADGTESQQQSSSVAVA-DDETRPVDKRDN------------------
Mvan_2649|M.vanbaalenii_PYR-1       ETYPTGAEPEQQTSPVALAEDDSTRPVDKRDSDN----------------
TH_2662|M.thermoresistible__bu      ----TTVEAPPQ---------DRT--------------------------
MSMEG_3032|M.smegmatis_MC2_155      QEHTDTTQTTPLENP------DQPRQS-----------------------
Rv2536|M.tuberculosis_H37Rv         QPEAQT---AAVATVER---EAPTEVIRTTESDTPTEVIR----------
Mb2565|M.bovis_AF2122/97            QPEAQT---AAVATVER---EAPTEVIRTTESDTPTEVIR----------
MMAR_2179|M.marinum_M               SNQAQATAPTAVATVER---DAPTEVIATTEQESPTEVIRTTEPEAKTET
MUL_1763|M.ulcerans_Agy99           SNQAQATAPTAVATVER---DAPTEVIATTEQESPTEVICTAEPEAKTET
MAV_3414|M.avium_104                GAQTEAHT-AAVATAEREA-ESPTETIPSAGDDPKTEVIR----------
MLBr_00520|M.leprae_Br4923          QTKEQT---AAVATAES---EAPTEIIYHQRA------------------
MAB_2839|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_3754|M.gilvum_PYR-GCK          -------------------------------
Mvan_2649|M.vanbaalenii_PYR-1       -------------------------------
TH_2662|M.thermoresistible__bu      -------------------------------
MSMEG_3032|M.smegmatis_MC2_155      -------------------------------
Rv2536|M.tuberculosis_H37Rv         ---TDTEA---------DQTKPGDEPKKD--
Mb2565|M.bovis_AF2122/97            ---TDTEA---------DQTKPGDEPKKD--
MMAR_2179|M.marinum_M               IATTESEASTEVIQLDEDETKTDEVPKKKKD
MUL_1763|M.ulcerans_Agy99           IATTESEASTEVIQLDEDETKTDEVPKKKKD
MAV_3414|M.avium_104                -----------------TEPEPGGEPGKA--
MLBr_00520|M.leprae_Br4923          -------------------------------
MAB_2839|M.abscessus_ATCC_1997      -------------------------------