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VAPTSSSVASELLMPWPSAAASGVVGWRTTATASQRYHRPMSDTPFAEPYPEQRPPWGVPPPGWDGSSRP APSTTPRSPGRWSLVAALALAVVSLGVGIVGWFHRQPHDKPSPAPSAPTFTSQQISDAKENVCAAHRIVR QAAVLNTNQANPVPGDPTGDLAVAANARLALYSGGDYLLRRLTAEPATPAELRDAVRSLANALQELAVNY LAGAPDSVVTPLRLALERDTRAVDPLCV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2473 | - | - | 100% (238) | POSSIBLE ALANINE AND PROLINE RICH MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv3901c | - | 3e-08 | 29.32% (133) | hypothetical protein Rv3901c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2500 | - | 1e-138 | 100.00% (238) | alanine and proline rich membrane protein |
| M. gilvum PYR-GCK | Mflv_3616 | - | 1e-18 | 41.98% (131) | putative alanine and proline rich membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3063 | - | 2e-08 | 28.10% (153) | hypothetical protein MMAR_3063 |
| M. avium 104 | MAV_5290 | - | 5e-06 | 30.56% (108) | hypothetical protein MAV_5290 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3933 | - | 2e-18 | 38.24% (170) | PUTATIVE putative putative alanine and proline rich membrane |
| M. ulcerans Agy99 | MUL_2307 | - | 2e-06 | 27.34% (139) | hypothetical protein MUL_2307 |
| M. vanbaalenii PYR-1 | Mvan_2801 | - | 2e-18 | 38.51% (148) | putative alanine and proline rich membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2473|M.tuberculosis_H37Rv MAPTSSSVASELLMPWPSAAASGVVGWRTTATASQRYHRPMSDTPFAEPY
Mb2500|M.bovis_AF2122/97 MAPTSSSVASELLMPWPSAAASGVVGWRTTATASQRYHRPMSDTPFAEPY
Mflv_3616|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2801|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3933|M.thermoresistible__bu ---MSTSISSSKDLTLSETRNESKPTARHAVSRTPVQVRPVRD-------
MMAR_3063|M.marinum_M ---------------------------------MT---------------
MUL_2307|M.ulcerans_Agy99 ---------------------------------MG---------------
MAV_5290|M.avium_104 ---MLVTPLAVQLMEPSIRDTVSKGDCRHLGGSMVGDLPPAPGQGPM---
Rv2473|M.tuberculosis_H37Rv PEQRPPWGVPPPGWDGSSRPAPSTTPRSPGRWSLVAALALAVVSLGVGIV
Mb2500|M.bovis_AF2122/97 PEQRPPWGVPPPGWDGSSRPAPSTTPRSPGRWSLVAALALAVVSLGVGIV
Mflv_3616|M.gilvum_PYR-GCK -----------------------------------MTLAAAVLALGIAVF
Mvan_2801|M.vanbaalenii_PYR-1 ---------------------------------MKSAIAVALLALGVSVF
TH_3933|M.thermoresistible__bu -------------------------------WTARTALPIAVVAVGLAGW
MMAR_3063|M.marinum_M --------TNPPPAAQWVPNYPPQPVASPRTWPLVALAIIAIVGVVLGAA
MUL_2307|M.ulcerans_Agy99 --------TELS----------PQPVASPRTWPLVALAIIAIVGVVLGAV
MAV_5290|M.avium_104 --------TGPPNPTQWAPAFPPQPPRS-RTWPAVALAAVAVL---LGGA
*:: :.
Rv2473|M.tuberculosis_H37Rv GWFHRQPHDK------PSPAPSAPTFTSQQISDAKENVCAAHRIVRQAAV
Mb2500|M.bovis_AF2122/97 GWFHRQPHDK------PSPAPSAPTFTSQQISDAKENVCAAHRIVRQAAV
Mflv_3616|M.gilvum_PYR-GCK ALIRTFDA--------------EPDYTEAQRGDAKAAVCAAFETVRTGVA
Mvan_2801|M.vanbaalenii_PYR-1 ALLRTLDH--------------GPDYTDEQRGAAETGICAAFDTVRTAVA
TH_3933|M.thermoresistible__bu ALFDVRSG--------------TADAPSPP--DSTARVCGAFQVVSTAIP
MMAR_3063|M.marinum_M ALVVALTHPGNAGSAAAPTTTASPTYTAEEIAAAHQKLCDVYKLAARSVQ
MUL_2307|M.ulcerans_Agy99 ALVVALTRPGNAGSAAAPTTTASPTYTAEEIAAAHQKLCEVYKLAARSVQ
MAV_5290|M.avium_104 ALVVALTRPTGGSSTVSSTTTTTPSYTAEQTAAAHQKLCDSYKLASRAVQ
. . . . : :* . . .
Rv2473|M.tuberculosis_H37Rv LNTNQANP-VPGDPTGDLAVAANARLALYSGGDYLLRRLTAEPATPAELR
Mb2500|M.bovis_AF2122/97 LNTNQANP-VPGDPTGDLAVAANARLALYSGGDYLLRRLTAEPATPAELR
Mflv_3616|M.gilvum_PYR-GCK TNTNVTPPGGSGDITGALAVAANARVALFDGGQYLLAKL--DPATPTDLA
Mvan_2801|M.vanbaalenii_PYR-1 TNTNVEPPGGSGDIAGALAAAANARVALFDGGQYLLARL--DPATPDDLA
TH_3933|M.thermoresistible__bu LQTHLDLG---EDPVAQTAVAGNARLALLGGGQYLLGTL--DAGTPEDLA
MMAR_3063|M.marinum_M IDTNGGDP-------------ALARVTGVNGAVMLEQALRTAPALAPDER
MUL_2307|M.ulcerans_Agy99 IDTNGGDA-------------ALAGVTGVNGAVMLEQALRTAPALAPDER
MAV_5290|M.avium_104 IDTNGDNP-------------AFAGISTVNAAVILEQAVRTSPELSAADR
:*: . * :: ... * : . .
Rv2473|M.tuberculosis_H37Rv DAVRSLANALQELAVNYLAGAP--DSVVTPLRLALERDTRAVDPLCV--
Mb2500|M.bovis_AF2122/97 DAVRSLANALQELAVNYLAGAP--DSVVTPLRLALERDTRAVDPLCV--
Mflv_3616|M.gilvum_PYR-GCK AEVRRFANQLMDIGAAATAGVPNTDEVQAGRLQDAEAASSAISERCA--
Mvan_2801|M.vanbaalenii_PYR-1 GEVRRFANQLMDIGAAATAGVPNTDPVQADRLRDAEAASTAVSDRCR--
TH_3933|M.thermoresistible__bu TAVRSFANSLQDIGIHALAGVPNTDPIQSGRMADSDAVRRQIVELCQ--
MMAR_3063|M.marinum_M DAAFALAEAYTNANAVASFSTGRGDPAWRAAADDVIAKDAQMRATCGGG
MUL_2307|M.ulcerans_Agy99 DAAFALAEAYTNANAVASFSTGRGDPAWRAAADDVIAKDAEMRATCGGG
MAV_5290|M.avium_104 AAALALAAAYSHAQATASLVQTRDDPVWRSAANDVNAKDSEMKRVCGG-
. :* . * : *