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M. tuberculosis H37Rv Rv2453c (mobA)

annotation: molybdopterin-guanine dinucleotide biosynthesis protein A
coordinates: 2753018 - 2753623
length: 201

AELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGTTTLVEHMVGILGQRCAPVFVMAAPGQPLPTLPVP
VLRDELPGLGPLPATGRGLRAAAEAGVRLAFVCAVDMPYLTVELIEDLARRAVQTDAEVVLPWDGRNHYL
AAVYRTDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAPMQPGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2453cmobA-100% (201)molybdopterin-guanine dinucleotide biosynthesis protein A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2480cmobA1e-112100.00% (201) molybdopterin-guanine dinucleotide biosynthesis protein A
M. gilvum PYR-GCKMflv_2618-2e-5159.22% (179) molybdopterin-guanine dinucleotide biosynthesis protein A
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1598-8e-3949.73% (185) molybdopterin-guanine dinucleotide biosynthesis protein A
M. marinum MMMAR_3801mobA4e-8679.90% (194) molybdopterin-guanine dinucleotide biosynthesis protein a
M. avium 104MAV_1719-1e-7167.71% (192) molybdopterin-guanine dinucleotide biosynthesis protein A
M. smegmatis MC2 155MSMEG_4644-9e-6266.11% (180) molybdopterin-guanine dinucleotide biosynthesis protein A
M. thermoresistible (build 8)TH_0356-8e-5162.13% (169) PROBABLE MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS
M. ulcerans Agy99MUL_3724mobA1e-8579.38% (194) molybdopterin-guanine dinucleotide biosynthesis protein A
M. vanbaalenii PYR-1Mvan_3963-8e-6062.89% (194) molybdopterin-guanine dinucleotide biosynthesis protein A

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2618|M.gilvum_PYR-GCK          -----------------------MGRDKATLVVDGGSGAGTTMVEHVVSV
Mvan_3963|M.vanbaalenii_PYR-1       ----MTSSLPLAAVVLAGGASRRMGRDKATLPFDGPSGT-TTMVERVLSV
TH_0356|M.thermoresistible__bu      -----------------------MGRDKATLVYDG-----STLVERTVNA
MSMEG_4644|M.smegmatis_MC2_155      -----MSAAPLAAVVLAGGASRRMGRDKATLVFEG-----ATLVERVVAA
Rv2453c|M.tuberculosis_H37Rv        MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGT---TTLVEHMVGI
Mb2480c|M.bovis_AF2122/97           MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGT---TTLVEHMVGI
MMAR_3801|M.marinum_M               MAGRESDAVSLAGVVLAGGESRRMGRDKATLVLPGGS---TTMVEHVLGI
MUL_3724|M.ulcerans_Agy99           MAGRESDAVSLAGVVLAGGESRRMGRDKATLVLPGGS---TTMVEHVLGI
MAV_1719|M.avium_104                MA----DSMQLAGIVLAGGESRRMGRDKATLPGPRGA---ATLLEYVVGV
MAB_1598|M.abscessus_ATCC_1997      -------MNQLAAVVLTGGASRRMGRDKATLRWCG-----ETLAGRVVRT
                                                           ********          *:    :  

Mflv_2618|M.gilvum_PYR-GCK          VGERCSPVFVVAAPGQALPALDAVVLRDEVGGVGPLLATGRGLRAAAEAG
Mvan_3963|M.vanbaalenii_PYR-1       VSARCEPVFVIAAPGQALPELDAVVLRDEVRGLGPLLATGRGLRAAAEAG
TH_0356|M.thermoresistible__bu      VAARCSPVFVVAAPGQALPELDAEVLRDELRGVGPLLATGRGLRAAAEAG
MSMEG_4644|M.smegmatis_MC2_155      VAQRCAPVFVIAAPGQPLPDLPAQVLRDEVRGVGPLVAAGRGLRAAAEAG
Rv2453c|M.tuberculosis_H37Rv        LGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAG
Mb2480c|M.bovis_AF2122/97           LGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAG
MMAR_3801|M.marinum_M               VGQRCEPVFVMAAQGQPLPPLQVPVLRDELRGLGPLPATGRGLRAAAEAG
MUL_3724|M.ulcerans_Agy99           VGQRCEPVFVMAAQGQPLPPLQVPVLRDELRGLGPLPATGRGLRAAAEAG
MAV_1719|M.avium_104                LTQRCDPIFVMAAPGQPLPEVSARIIRDEIRGQGPLPATGRGLRAAAEAG
MAB_1598|M.abscessus_ATCC_1997      VGSRCAPVIVVCAPHQDVGDVRAIVIEDLWPGQGPLVAMGQGLRAAAERG
                                    :  ** *::*:.*  * :  : . ::.*   * *** * *:******* *

Mflv_2618|M.gilvum_PYR-GCK          REYAFVSAVDMPALTSDVIDVLAGPARSS-GADVVLPWDGRDHYLAGIYR
Mvan_3963|M.vanbaalenii_PYR-1       RSHAFVSAVDMPALTPEIIDVLAGPAERL-NADVVLPWDGRDHYLAGIYR
TH_0356|M.thermoresistible__bu      RELAFVCAVDMPFLTPEVIDTLAGPAARIPGVEIVLPWDGREQYLAGIYR
MSMEG_4644|M.smegmatis_MC2_155      CELAFVCAVDMPYLSAELIDTLVDPARRL-GVDIVLPWDGRDHYLAGIYR
Rv2453c|M.tuberculosis_H37Rv        VRLAFVCAVDMPYLTVELIEDLARRAVQT-DAEVVLPWDGRNHYLAAVYR
Mb2480c|M.bovis_AF2122/97           VRLAFVCAVDMPYLTVELIEDLARRAVQT-DAEVVLPWDGRNHYLAAVYR
MMAR_3801|M.marinum_M               ARFAFVCAVDMPGLTVDLIDDLVRSAIET-DAEVVLPWDGRSHYLAAIYR
MUL_3724|M.ulcerans_Agy99           ARFAFVCAVDMPGLTVDLIDDLVRSAIET-DAEVVLPWDGRSHYLAAIYR
MAV_1719|M.avium_104                ARYAFVCAVDMPLLSPELIDDLVHLATET-NAEVVLPWDGRSHYLASLYR
MAB_1598|M.abscessus_ATCC_1997      AGRAFVCAVDMPLVAPALIDELAAGGDRI----VLATAGGRDHYLAAVYD
                                       ***.***** ::  :*: *.  .       :: . .**.:***.:* 

Mflv_2618|M.gilvum_PYR-GCK          TALHTVVSDLVQAGARSMRAFVDRVDTQRIVLPEQPALANVNTVADLEAI
Mvan_3963|M.vanbaalenii_PYR-1       TALHTVVAALLDAGERSMRALVDAVDTQRIVLPEQPALANVNTAADLAAI
TH_0356|M.thermoresistible__bu      TALADRITGLIEAGERSMKALITRSDTQQIVLPAQRALTNVNTPAEYESL
MSMEG_4644|M.smegmatis_MC2_155      TDLATTIGDLVGAGERSMRALADRVDTQRLVMEPQKALTNVNTPDDLP--
Rv2453c|M.tuberculosis_H37Rv        TDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAP
Mb2480c|M.bovis_AF2122/97           TDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAP
MMAR_3801|M.marinum_M               TDLAERVDALVAAGERKMSALADSSDTQRIVMSDSAPLANVNTAADLPAP
MUL_3724|M.ulcerans_Agy99           TDLAERVDALVAAGERKTSALADSSDTQRIVMSDSAPLANVNTAADLPAP
MAV_1719|M.avium_104                TDLAERIDRLVAGGARSMRALIDASDAQQIVLPESRFLANVNTEADLRAL
MAB_1598|M.abscessus_ATCC_1997      VGLCETIDELTTAGERRLGTLVERVGAQRISISEPKWIVNVNTAADLAAL
                                    . *   :  *  .* *   ::    .: :: :     :.***:       

Mflv_2618|M.gilvum_PYR-GCK          RPPRLVQQIHHR-----------
Mvan_3963|M.vanbaalenii_PYR-1       LPPRLGQQTAVTGASGTGNSIPN
TH_0356|M.thermoresistible__bu      TTISPANEMS-------------
MSMEG_4644|M.smegmatis_MC2_155      -----------------------
Rv2453c|M.tuberculosis_H37Rv        MQPGR------------------
Mb2480c|M.bovis_AF2122/97           MQPGR------------------
MMAR_3801|M.marinum_M               VRPGH------------------
MUL_3724|M.ulcerans_Agy99           VRPGH------------------
MAV_1719|M.avium_104                AQARA------------------
MAB_1598|M.abscessus_ATCC_1997      PPLP-------------------