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TPNRGIDEDFLDLPRQQLADAALSAAATAGASHADLRVHRISTEIIQLRDGELETAVISRELGLAVRVIV AGTWGFASHAELAPDVAAATARHAVHVATVLAALNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIA VLRDYSGRLLDADGIDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAAGNFESMRTLAP PTARGWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDLVIDPTNLWLTIHESIGHATEYDRAIG YEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTAEFGLATVGYDDEGVAAQSWDLVRDGVFVGYQLDRAF APRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTADLIGRVDDGIYIVGDKSWSIDMQRYNFQF TGQRFFRIRGGQLYGQLRDVAYQSSTTDFWNAMEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALF RGVNVLNTRTEGGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2315c | - | - | 100% (505) | hypothetical protein Rv2315c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2342c | - | 0.0 | 100.00% (505) | hypothetical protein Mb2342c |
| M. gilvum PYR-GCK | Mflv_2732 | - | 0.0 | 78.04% (501) | peptidase U62, modulator of DNA gyrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1718 | - | 0.0 | 76.20% (500) | peptidase U62, modulator of DNA gyrase |
| M. marinum M | MMAR_3616 | - | 0.0 | 86.93% (505) | hypothetical protein MMAR_3616 |
| M. avium 104 | MAV_2091 | - | 0.0 | 85.35% (505) | modulator of DNA gyrase |
| M. smegmatis MC2 155 | MSMEG_4464 | - | 0.0 | 81.39% (505) | modulator of DNA gyrase |
| M. thermoresistible (build 8) | TH_0101 | - | 0.0 | 79.13% (503) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1249 | - | 0.0 | 86.93% (505) | hypothetical protein MUL_1249 |
| M. vanbaalenii PYR-1 | Mvan_3804 | - | 0.0 | 79.84% (501) | peptidase U62, modulator of DNA gyrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2732|M.gilvum_PYR-GCK MTA-RTVDADFLALPRHALADAALTAAVQAGAGYADLRIHAITTETVQLR
Mvan_3804|M.vanbaalenii_PYR-1 MTA-RTVDPDFLALPRHALADAALTAAVQAGAGYADLRIHAITTETVHLR
Rv2315c|M.tuberculosis_H37Rv MTPNRGIDEDFLDLPRQQLADAALSAAATAGASHADLRVHRISTEIIQLR
Mb2342c|M.bovis_AF2122/97 MTPNRGIDEDFLDLPRQQLADAALSAAATAGASHADLRVHRISTEIIQLR
MMAR_3616|M.marinum_M MTPNRGIDAEFLDLPRLALADAALSAATAAGASYADLRIQRIGTEIIHLR
MUL_1249|M.ulcerans_Agy99 MTPNRGIDAEFLDLPRLALADAALSAATAAGASYADLRIQRIGTEIIHLR
MAV_2091|M.avium_104 MTPNRGIDADFLDLPRHELADAALSAATAAGASHADLRVHRLITEIIQLR
MSMEG_4464|M.smegmatis_MC2_155 MTAQRQVDADFLGLPRHELADAALSAAVAAGASYADLRIHRITTEIIQLR
TH_0101|M.thermoresistible__bu VTAHRNVDADFVSLPRTALADAALTAAVAAGASYADLRIHRITTEMVVLR
MAB_1718|M.abscessus_ATCC_1997 --MTRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLR
* :* :*: *** ******.** ***.:****:: : .* : **
Mflv_2732|M.gilvum_PYR-GCK DGALETAVTDYEIGLAVRVIVDGTWGFASHAQLDTAAAADTARRAVRVAT
Mvan_3804|M.vanbaalenii_PYR-1 DGALETAVTGYEIGLAVRVIVDGTWGFASHAELDTAAAADTARRAVRVAT
Rv2315c|M.tuberculosis_H37Rv DGELETAVISRELGLAVRVIVAGTWGFASHAELAPDVAAATARHAVHVAT
Mb2342c|M.bovis_AF2122/97 DGELETAVISRELGLAVRVIVAGTWGFASHAELAPDVAAATARHAVHVAT
MMAR_3616|M.marinum_M DGELETAILSRELGFAVRVIVNGTWGFASHAELSASAAADTARRAVRVAT
MUL_1249|M.ulcerans_Agy99 DGELETAILSRELGFAVRVIVNGTWGFASHAELSASAAADTARRAVRVAT
MAV_2091|M.avium_104 DGELETAVINREVGLAVRVIVDGTWGFASHAELAPSVAAETARRAVHVAT
MSMEG_4464|M.smegmatis_MC2_155 DGELETSVLDREIGLAVRVIVDGTWGFASNAELAPDVAAETARRAVAVAT
TH_0101|M.thermoresistible__bu DGELQTAAVDREVGLAVRVIVDGTWGFASHADLTPTVAAETARRAVRVAT
MAB_1718|M.abscessus_ATCC_1997 DEQVETAVSGRTIGLAVRVIVDGTWGFASHVQLDTTAAAETARRAVAVAR
* ::*: . :*:****** *******:.:* . .** ***:** **
Mflv_2732|M.gilvum_PYR-GCK RLAALNAERIELAPEPVYRDVSWVSDYRIDPFAVPTQDKIEVLEDYSGRL
Mvan_3804|M.vanbaalenii_PYR-1 TLAPLNAERIELAPEPVYRDVSWVSDYRIDPFGIAAQDKIAVLEDYSGRL
Rv2315c|M.tuberculosis_H37Rv VLAALNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIAVLRDYSGRL
Mb2342c|M.bovis_AF2122/97 VLAALNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIAVLRDYSGRL
MMAR_3616|M.marinum_M TLAALNTERVELAPEPVYTDAVWVSNYQIDPFSLPASEKIAVLEDYSGRL
MUL_1249|M.ulcerans_Agy99 TLAALNTERVELAPEPVYTDAVWVSNYQIDPFSLPASEKIAVLEDYSGRL
MAV_2091|M.avium_104 TLATLSSERVELAPEPVYRDATWVSSYRIDPFDVSAADKIGVLGDYSGRL
MSMEG_4464|M.smegmatis_MC2_155 ALAPLNGERIELAPEPVYRDATWVSDYRVDPFSVSAADKIAALDDYSGRL
TH_0101|M.thermoresistible__bu TLAPLNAERIELAPEPVYRDASWVSDYRIDPFEVPGADKIEVLADYSARL
MAB_1718|M.abscessus_ATCC_1997 GLRSLNRERVELADEPVYADVQWVSDYAIDPFGVPQADKIAVLQEYSARL
* .*. **:.** **** *. ***.* :*** :. :** .* :**.**
Mflv_2732|M.gilvum_PYR-GCK LASEGIDHVSAWLNMAKEQTFYADTFGSTITQQRVRVLPRCDAVTVDPAA
Mvan_3804|M.vanbaalenii_PYR-1 LASDGVDHVSASLHTAKEQTFYADTFGSSITQQRVRVLPNVEAVAVDAAA
Rv2315c|M.tuberculosis_H37Rv LDADGIDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAA
Mb2342c|M.bovis_AF2122/97 LDADGIDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAA
MMAR_3616|M.marinum_M LSADGVDHASASLNAVKEQTFYADTYGSSITQQRVRLHPSLEAVTVDSGA
MUL_1249|M.ulcerans_Agy99 LSADGVDHASASLNAVKEQTFYADTYGSSITQQRVRLHPSLEAVTVDSGA
MAV_2091|M.avium_104 LAADGIDHVSALLTAVKEQTFYADTFGSSITQQRVRVLPSLEAVTVDAQA
MSMEG_4464|M.smegmatis_MC2_155 LAADGVDHVSAGVHAVKEQTFYADTFGSSITQQRVRVLPTLEAVAVDSAA
TH_0101|M.thermoresistible__bu LAGDGVDHVSAGMQAVKEQTFYADTFGSSITQQRVRVEPMLEAVSVDADA
MAB_1718|M.abscessus_ATCC_1997 LASDGVDHASASLTAVKEQTFYADTFGSSITQQRVRVMSQLDAIAVDAAT
* .:*:**.** : .*********:**:*******: . :*::**. :
Mflv_2732|M.gilvum_PYR-GCK GSFETMSTLAPPMGRGWEAVVGNEVWDWAGELAELPTLLAEKAKAPSVIA
Mvan_3804|M.vanbaalenii_PYR-1 GSFETMSTLAPPTARGWEAVVGDEVWDWAGELAELPSLLAEKVKAPSVVA
Rv2315c|M.tuberculosis_H37Rv GNFESMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMP
Mb2342c|M.bovis_AF2122/97 GNFESMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMP
MMAR_3616|M.marinum_M GIFDSMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKTKAPSVTA
MUL_1249|M.ulcerans_Agy99 GIFDSMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKTKAPSVTA
MAV_2091|M.avium_104 GSFDSMRTLAPPMGRGWEALAGDEVWNWTDELAQLPSLLAEKVKAPTVVP
MSMEG_4464|M.smegmatis_MC2_155 GSFETMRTLAPPMGRGWEAVADADVWDWAGELAELPTLLAEKTKAPSVVA
TH_0101|M.thermoresistible__bu GGFDSMRTLAPPTARGWEVLAGDEVWDWSGEIAEIPELLAEKVKAPTVTP
MAB_1718|M.abscessus_ATCC_1997 GSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEKVKAPSVVA
* *::* ***** .****.: . :*:*: *: ::* **:**.:**:* .
Mflv_2732|M.gilvum_PYR-GCK GPKDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGRL
Mvan_3804|M.vanbaalenii_PYR-1 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGRM
Rv2315c|M.tuberculosis_H37Rv GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTL
Mb2342c|M.bovis_AF2122/97 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTL
MMAR_3616|M.marinum_M GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGSM
MUL_1249|M.ulcerans_Agy99 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGSM
MAV_2091|M.avium_104 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAM
MSMEG_4464|M.smegmatis_MC2_155 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTM
TH_0101|M.thermoresistible__bu GPTDLVIDPSNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTL
MAB_1718|M.abscessus_ATCC_1997 GPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAM
**.******:************************************** :
Mflv_2732|M.gilvum_PYR-GCK RYGSSVMNVTADRTVEHGLATVGFDDEGVRAQSWDLVRDGLFVGYQLDRV
Mvan_3804|M.vanbaalenii_PYR-1 QYGSPVMNVTADRTVAHGLASVGFDDEGVRAQSWDLVRDGVFVGYQLDRV
Rv2315c|M.tuberculosis_H37Rv RYGSPVMNVTADRTAEFGLATVGYDDEGVAAQSWDLVRDGVFVGYQLDRA
Mb2342c|M.bovis_AF2122/97 RYGSPVMNVTADRTAEFGLATVGYDDEGVAAQSWDLVRDGVFVGYQLDRA
MMAR_3616|M.marinum_M RYGSPVMNVTADRTVEFGLASIGYDDEGVASQSWDLVRDGVFVGYQLDRV
MUL_1249|M.ulcerans_Agy99 RYGSPVMNVTADRTVEFGLASIGYDDEGVASQSWDLVRDGVFVGYQLDRV
MAV_2091|M.avium_104 RYGSPVMNVTADRTVEFGLATIGYDDEGVAAQSWDLVRDGIFTGYQLDRV
MSMEG_4464|M.smegmatis_MC2_155 RYGSEVMNVTADRTVEHGLATVGFDDEGVRSQSWDLVRDGIFVGYQLDRV
TH_0101|M.thermoresistible__bu RYGSPVMNVTADRTVEYGLATVGYDDEGVQAQRWDLIRDGILVGYQLDRV
MAB_1718|M.abscessus_ATCC_1997 KYGSPVMNVTADRNEVHGLASVGYDDEGVASQRWDLVRDGIFVGYQLDRV
:*** ********. .***::*:***** :* ***:***::.******.
Mflv_2732|M.gilvum_PYR-GCK FAPRLGVGRSNGCSYADSAQHVPIQRMANVSLQPAPEDVSTEELIGRVSD
Mvan_3804|M.vanbaalenii_PYR-1 FAPRLGVGRSNGCSYADSPHHVPIQRMANVSLQPGAEDLSTADLIAQVSD
Rv2315c|M.tuberculosis_H37Rv FAPRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTADLIGRVDD
Mb2342c|M.bovis_AF2122/97 FAPRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTADLIGRVDD
MMAR_3616|M.marinum_M FAPRLGQPRSNGCSYADSPHHVPIQRMANVSLQPGAEDLSTADLIGRVED
MUL_1249|M.ulcerans_Agy99 FAPRLGQPRSNGCSYADSPHHVPIQRMANVSLQPGAEDLSTADLIGRVED
MAV_2091|M.avium_104 FARRLGHPRSNGCSYADSPHHVPIQRMANVSLQPAPEQISTDDLIARVED
MSMEG_4464|M.smegmatis_MC2_155 FAPRLGETRSNGCSYADSPHHVPIQRMANVSLRPAAEDLSTDDLIARVSD
TH_0101|M.thermoresistible__bu FAPRLGVARSNGCSYADSPHHVPIQRMANVSLQPAEQDVTTADLIARVSD
MAB_1718|M.abscessus_ATCC_1997 FAPRLGQERSNGCSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVED
** *** **********.:*********:**:.. :: :* :**. *.*
Mflv_2732|M.gilvum_PYR-GCK GLYIVGDKSWSIDMQRYNFQFTGQRFFKITDGRLDGQVRDVAYQATTTDF
Mvan_3804|M.vanbaalenii_PYR-1 GLYVVGDKSWSIDMQRYNFQFTGQRFYRIRDGRLDGQVRDVAYQATTTDF
Rv2315c|M.tuberculosis_H37Rv GIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQLYGQLRDVAYQSSTTDF
Mb2342c|M.bovis_AF2122/97 GIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQLYGQLRDVAYQSSTTDF
MMAR_3616|M.marinum_M GIYIVGDKSWSIDMQRYNFQFTGQRFFRIRDGRLDGQLRDIAYQATTTEF
MUL_1249|M.ulcerans_Agy99 GIYIVGDKSWSIDMQRYNFQFTGQRFFRIRDGRLDGQLRDIAYQATTTEF
MAV_2091|M.avium_104 GIYIVGDKSWSIDMQRYNFQFTGQRFYRIRGGRLDGQLRDVAYQATTTDF
MSMEG_4464|M.smegmatis_MC2_155 GLYIVGDKSWSIDMQRYNFQFTGQRFYRIRNGRLDGQVRDVAYQATTTDF
TH_0101|M.thermoresistible__bu GLYIVGDKSWSIDMQRYNFQFTGQRFYRIRNGRLAGQVRDVAYQSTTTDF
MAB_1718|M.abscessus_ATCC_1997 GIYIVGDKSWSIDMQRYNFQFTGQRFYRIRGGKLDGQLRDVAYQATTTDF
*:*:**********************::* .*:* **:**:***::**:*
Mflv_2732|M.gilvum_PYR-GCK WGALEAVGGPSTWRLGGAFNCGKAQPGQVAAVSHGCPSALFRGVNILNTR
Mvan_3804|M.vanbaalenii_PYR-1 WGALEAVGGQSTWRLGGAFNCGKAQPGQVAAVSHGCPSALFRGINVLNTR
Rv2315c|M.tuberculosis_H37Rv WNAMEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRGVNVLNTR
Mb2342c|M.bovis_AF2122/97 WNAMEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRGVNVLNTR
MMAR_3616|M.marinum_M WNSMEAVGGPSTWRLGGAINCGKAQPGQVAPVSHGCPSALFRGVNILNTR
MUL_1249|M.ulcerans_Agy99 WNSMEAVGGPSTWRLGGAINCGKAQPGQVAPVSHGCPSALFRGVNILNTR
MAV_2091|M.avium_104 WNSMEAVGGPATWRLGGAFNCGKAQPGQIAPVSHGCPSALFRGVNVLNTR
MSMEG_4464|M.smegmatis_MC2_155 WGSMEAVGGPSTWRLGGAFNCGKAQPGQVAPVSHGCPSALFRGVNVLNTR
TH_0101|M.thermoresistible__bu WGAMEAVGGPSTWQLGGAFNCGKAQPGQVAPVSHGCPSALFRGINVLNTR
MAB_1718|M.abscessus_ATCC_1997 WGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAVSHGCPSALFRGVNVLNTK
*.::***** :**::***:*********:*.************:*:***:
Mflv_2732|M.gilvum_PYR-GCK EESGR--
Mvan_3804|M.vanbaalenii_PYR-1 EEGGR--
Rv2315c|M.tuberculosis_H37Rv TEGGR--
Mb2342c|M.bovis_AF2122/97 TEGGR--
MMAR_3616|M.marinum_M TEGGR--
MUL_1249|M.ulcerans_Agy99 TEGGR--
MAV_2091|M.avium_104 TEGGR--
MSMEG_4464|M.smegmatis_MC2_155 TEAGR--
TH_0101|M.thermoresistible__bu DEGR---
MAB_1718|M.abscessus_ATCC_1997 EEGGSSR
*.