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TTVDFHFDPLCPFAYQTSVWIRDVRAQLGITINWRFFSLEEINLVAGKKHPWERDWSYGWSLMRIGALLR RTNMSLLDRWYAAIGHELHTLGGKPHDPAVARRLLCDVGVNAAILDAALDDPTTHDDVRADHQRVVAAGG YGVPTLFLDGQCLFGPVLVDPPAGPAALNLWSVVTGMAGLPHVYELQRPKSPADVELIAQQLRPYLDGRD WVSINRGEIVDIDRLAGRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2286c | - | - | 100% (230) | hypothetical protein Rv2286c |
| M. tuberculosis H37Rv | Rv2466c | - | 4e-20 | 29.90% (194) | hypothetical protein Rv2466c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2308c | - | 1e-78 | 100.00% (133) | hypothetical protein Mb2308c |
| M. gilvum PYR-GCK | Mflv_2578 | - | 1e-18 | 30.77% (195) | DsbA oxidoreductase |
| M. leprae Br4923 | MLBr_01485 | - | 1e-17 | 30.73% (192) | hypothetical protein MLBr_01485 |
| M. abscessus ATCC 19977 | MAB_1572 | - | 3e-20 | 33.33% (195) | hypothetical protein MAB_1572 |
| M. marinum M | MMAR_3434 | - | 1e-117 | 83.77% (228) | hypothetical protein MMAR_3434 |
| M. avium 104 | MAV_1706 | - | 3e-17 | 30.89% (191) | hypothetical protein MAV_1706 |
| M. smegmatis MC2 155 | MSMEG_4688 | - | 3e-19 | 30.69% (189) | hypothetical protein MSMEG_4688 |
| M. thermoresistible (build 8) | TH_0346 | - | 6e-23 | 31.96% (194) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2708 | - | 1e-118 | 83.77% (228) | hypothetical protein MUL_2708 |
| M. vanbaalenii PYR-1 | Mvan_1123 | - | 5e-85 | 64.44% (225) | DSBA oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2578|M.gilvum_PYR-GCK --MSE--KSRADFWFDPLCPWAWITSRWVLEAEKVRDIEVNFHVMSLAVL
MAB_1572|M.abscessus_ATCC_1997 --MSADKKDLAEFWFDPLCPWCWITSRWILEVQKVRDIEVKFRVMSLAVL
MSMEG_4688|M.smegmatis_MC2_155 --MAQ--KDVAGFWFDPLCPWCWITSRWILEVEKVRDIEVQFHVMSLAVL
MAV_1706|M.avium_104 MAQQAPAKNKADFWFDPLCPWAWITSRWILEVEKVRDIEVNFHVMSLAVL
TH_0346|M.thermoresistible__bu ----MAAKDTADFWFDPLCPWAWITSRWILEVEKVRDIDVNFRVMSLAVL
MLBr_01485|M.leprae_Br4923 MPEKASVKYQADLWFDPLCPWCWITSRWILEVEKVRDVEVHFHVMSLAIL
Rv2286c|M.tuberculosis_H37Rv -------MTTVDFHFDPLCPFAYQTSVWIRDVRAQLGITINWRFFSLEEI
Mb2308c|M.bovis_AF2122/97 -------MTTVDFHFDPLCPFAYQTSVWIRDVRAQLGITINWRFFSLEEI
MMAR_3434|M.marinum_M ------MNTVVDFHFDPMCPFAYQTSVWIRDVRAQLGITINWRFFSLEEI
MUL_2708|M.ulcerans_Agy99 -----MMNTVVDFHFDPMCPFAYQTSVWIRDVRAQLGITINWRFFSLEEI
Mvan_1123|M.vanbaalenii_PYR-1 ---MTNPPVSVDFHFDIMCPYAYQTSRWIRAVRDQTGLHVNWRFFSLEEI
. : ** :**:.: ** *: .. .: ::::.:** :
Mflv_2578|M.gilvum_PYR-GCK NEGRD-LPEEYLEMMKTAWGPVRVAIAAEQAKGPEVLGPLYTAFGTRIHN
MAB_1572|M.abscessus_ATCC_1997 NEGRDNLPERYQELMKTAWGPVRVAIAAEQAKGQEILEPLYTAMGNRIHN
MSMEG_4688|M.smegmatis_MC2_155 NEGRD-LPEEYQEMMKKAWGPVRVAIAAEQLKGSEILSPLYTAMGTRIHN
MAV_1706|M.avium_104 NENREGLPDEYRERLAKAFGPVRVAIAAEQAHGAEVLAPLYTAMGTRIHN
TH_0346|M.thermoresistible__bu NEGRD-VPDEYRETMKKAWAPVRVAIAAEQAHGREVLSPLYTAMGTRIHN
MLBr_01485|M.leprae_Br4923 NENREDLTENYLENITKAWGPARVVIAAEQANGASVLDPLYTAMGIRIHN
Rv2286c|M.tuberculosis_H37Rv NLVAG-KKHPWERDWSYGWSLMRIGALLRRTN-MSLLDRWYAAIGHELHT
Mb2308c|M.bovis_AF2122/97 NLVAG-KKHPWERDWSYGWSLMRIGALLRRTN-MSLLDRWYAAIGHELHT
MMAR_3434|M.marinum_M NRAEG-KKHPWERDWSYGWSLMRIGALLRRSD-MSLLDQWYEAIGHELHV
MUL_2708|M.ulcerans_Agy99 NRAEG-KKHPWERDWSYGWSLMRIGALLRRSD-MSLLDQWYEAIGHELHV
Mvan_1123|M.vanbaalenii_PYR-1 NRQEG-KKHPWEREWSYGWSMMRIGALLRRRS-MTDVDAWYERAARALHV
* . : . .:. *: .: : * . :*
Mflv_2578|M.gilvum_PYR-GCK LGYRETDPDFTRVIAESLDEVGLPAELAAAATSTDYDEALRKSHHEGMDP
MAB_1572|M.abscessus_ATCC_1997 Q----DNKDLPAVIAESLAEVGLPADLADAAESTDYDEALRASHHAGMDK
MSMEG_4688|M.smegmatis_MC2_155 Q----DNKNFDEVIAQSLEEVGLPAELAEAATTDKYDEALRRSHHAGMDA
MAV_1706|M.avium_104 E----GNKDLTDVIKQSLAEVGLPAELAEAADTDAYDDALRKSHHAGMDP
TH_0346|M.thermoresistible__bu Q----GNKDLDEVIAQSLAEVGLPAELAEAATTDRYDEALRKSHHEGMDA
MLBr_01485|M.leprae_Br4923 E----DNKNLDEVIKRSLADTGLPAELAAAAQSNAYDDALRESHHAGMDP
Rv2286c|M.tuberculosis_H37Rv LG---GKPHDPAVARRLLCDVGVNAAILDAALDDPTTHDDVRADHQRVVA
Mb2308c|M.bovis_AF2122/97 LG---GKPHDPAVARRLLCDVGVNAAILDAALDDPTTHDDVRADH-----
MMAR_3434|M.marinum_M LG---GKPHDPAVARRLLGDIGVEAAVVDAALDDPSTHDEIRAEHQRVVD
MUL_2708|M.ulcerans_Agy99 LG---GKPHDPAVARRLLGDIGVEAAVVDAALDDPSTHDEIRAEHQRVVD
Mvan_1123|M.vanbaalenii_PYR-1 EG---HKPHEKAVARHLLEELGFDPGLVDEAVADPTASDEVMADHNRVVD
. . * . * : *. . : * :.*
Mflv_2578|M.gilvum_PYR-GCK VGPDVGTPTIHVNGVAFFGPVLSRIPRGEEAGKLWDASVIFASYPHFWEL
MAB_1572|M.abscessus_ATCC_1997 VGPDVGTPTIHVNGVAFFGPVISKIPRGEEAGKLWDASVIFASYPHFYEL
MSMEG_4688|M.smegmatis_MC2_155 VGDDVGTPTIHVNGVAFFGPVLSRIPRGEEAGKLWDASVTFASYPHFWEL
MAV_1706|M.avium_104 VGDDVGTPTIHVNNVAFFGPVLSRIPRGEEAGKLWDASVTFASYPHFFEL
TH_0346|M.thermoresistible__bu VGEDVGTPTIHVNNVAFFGPVLSRIPRGEEAGKLWDASVTFASYPHFWEL
MLBr_01485|M.leprae_Br4923 VGDDVGTPTVHVNGVAFFGPVLSKIPRGEEAGKLWDASLTLAAYPHFFEL
Rv2286c|M.tuberculosis_H37Rv AGGYGVPTLFL-DGQCLFGPVLVDPPAGPAALNLWSVVTGMAGLPHVYEL
Mb2308c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3434|M.marinum_M ANGYGVPTLFM-DGQCLFGPVLVDPPTGADALKLWNVVSGMAELPHVYEL
MUL_2708|M.ulcerans_Agy99 ANGYGVPTLFM-DGQCLFGPVLVDPPTGADALKLWNVVSGMAELPHVYEL
Mvan_1123|M.vanbaalenii_PYR-1 AGGYGVPTLFFPDGQCLFGPVLIDPPAGEAALRLWDAVVAWTEFPHLYEL
Mflv_2578|M.gilvum_PYR-GCK KRTRTESPEFD--------------------------------
MAB_1572|M.abscessus_ATCC_1997 KRTRTEPPTFD--------------------------------
MSMEG_4688|M.smegmatis_MC2_155 KRSRTESPEFD--------------------------------
MAV_1706|M.avium_104 KRTRDEKPEFD--------------------------------
TH_0346|M.thermoresistible__bu KRTRTEAPEFD--------------------------------
MLBr_01485|M.leprae_Br4923 KRTRTEPPQFA--------------------------------
Rv2286c|M.tuberculosis_H37Rv QRPKSPADVELIAQQLRPYLDGRDWVSINRGEIVDIDRLAGRS
Mb2308c|M.bovis_AF2122/97 -------------------------------------------
MMAR_3434|M.marinum_M QRPKSAADAELIGQSLRPYLDGRDWVSINRGKVIDVDRLAGR-
MUL_2708|M.ulcerans_Agy99 QRPKSAADAELIGQSLRPYLDGRDWVSINRGKVIDVDRLAGR-
Mvan_1123|M.vanbaalenii_PYR-1 QRPKSTADQLAIAEAFRPYLEARDWVSINRGKVVGFDDLR---