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GQIVAGEIGGQRTTPVGGGLPLACCLDGRPPIVPHRRRRRIAALRSVLRMRDTPRPARSRCDQVTSHAVL IGWRAVPRRHGGELPRRGALALGCIALLLMGIVGCTTVTDGTAMPDTNVAPAYRSSVSASVSASAATSSI RESQRQQSLTTKAIRTSCDALAATSKDAIDKVNAYVAAFNQGRNTGPTEGPAIDALNNSASTVSGSLSAA LSAQLGDALNAYVDAARAVANAIGAHASTAEFNRRVDRLNDTKTKALTMCVAAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2240c | - | - | 100% (265) | hypothetical protein Rv2240c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2264c | - | 1e-147 | 99.62% (265) | hypothetical protein Mb2264c |
| M. gilvum PYR-GCK | Mflv_2782 | - | 3e-41 | 47.42% (194) | hypothetical protein Mflv_2782 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1885 | - | 2e-18 | 31.28% (179) | hypothetical protein MAB_1885 |
| M. marinum M | MMAR_3333 | - | 2e-83 | 77.50% (200) | hypothetical protein MMAR_3333 |
| M. avium 104 | MAV_2197 | - | 5e-66 | 72.02% (168) | hypothetical protein MAV_2197 |
| M. smegmatis MC2 155 | MSMEG_4322 | - | 3e-40 | 51.14% (176) | hypothetical protein MSMEG_4322 |
| M. thermoresistible (build 8) | TH_1340 | - | 1e-43 | 44.64% (233) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1309 | - | 7e-83 | 76.50% (200) | hypothetical protein MUL_1309 |
| M. vanbaalenii PYR-1 | Mvan_3751 | - | 4e-46 | 55.00% (180) | hypothetical protein Mvan_3751 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2240c|M.tuberculosis_H37Rv MGQIVAGEIGGQRTTPVGGGLPLACCLDGRPPIVPHRRRRRIAALRSVLR
Mb2264c|M.bovis_AF2122/97 MGQIVAGEIGGQRTTPVGGGLPLACCLDGRPPIVPHRRRRRIAALRSVLR
MMAR_3333|M.marinum_M --------------------------------------------------
MUL_1309|M.ulcerans_Agy99 --------------------------------------------------
MAV_2197|M.avium_104 --------------------------------------------------
Mflv_2782|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3751|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4322|M.smegmatis_MC2_155 --------------------------------------------------
TH_1340|M.thermoresistible__bu --------------------------------------------------
MAB_1885|M.abscessus_ATCC_1997 --------------------------------------------------
Rv2240c|M.tuberculosis_H37Rv MRDTPRPARSRCDQVTSHAVLIGWRAVPRRHG----GELPRRGALALGCI
Mb2264c|M.bovis_AF2122/97 MRDTPRPARSRCDQVTSHAVLIGWRAVPRRHG----GELPRRGALALGCI
MMAR_3333|M.marinum_M -------------------MLIGWRAVPRRHGGAFSGSRARRGAQALGCI
MUL_1309|M.ulcerans_Agy99 -------------------MLIGWRAVPRRHGGAFSGSRARRGAQALGCI
MAV_2197|M.avium_104 -------------------------------------------------M
Mflv_2782|M.gilvum_PYR-GCK ----------------------MRNGWL---TAPR----VRLAGLVTGTS
Mvan_3751|M.vanbaalenii_PYR-1 ---------------------------------------MRLAAFVTGMC
MSMEG_4322|M.smegmatis_MC2_155 --------------------------------------------MALGGS
TH_1340|M.thermoresistible__bu -----------------MVPHMHRRGVARDTAAPGGFRGRRLTGSVVGGL
MAB_1885|M.abscessus_ATCC_1997 ---------------------------------------MRMAALLIALA
Rv2240c|M.tuberculosis_H37Rv ALLLMGIVGCTTVTDGTAMPDTNVAPAYRSSVSASVSASAATSSIRESQR
Mb2264c|M.bovis_AF2122/97 ALLLMGIVGCTTVTDGTAMPDTNVAPAYRSSVSASVSASAATSSIRESQR
MMAR_3333|M.marinum_M AVLLMGIVGCTSVTDGTATPDTKVAPAYRSSVSMSISASAATSSVRESQR
MUL_1309|M.ulcerans_Agy99 AVLLMGIVGCTSVTDGTATPDTKVAPAYRSSVSLSISASAATSSVRESQR
MAV_2197|M.avium_104 AAALIGIVGCTSVTNGTATPDTRVAPAYRQSVSASVSASSVTSSVRESQR
Mflv_2782|M.gilvum_PYR-GCK AVLAMVVVGCTYVTDGDAAVADGEAPLYRASVTAASEEAAASSSAREAER
Mvan_3751|M.vanbaalenii_PYR-1 ATLAMIVVGCTNFTDGDAAVAEGEAPLYRASVSASIEESAASSSARESER
MSMEG_4322|M.smegmatis_MC2_155 AVIAMVVVGCSTVTGGTAQVDPAEAPVYRASVSASIEASSLTSAARESER
TH_1340|M.thermoresistible__bu AALAMVVVGCTSLTAGSGQADAEEVPVYRASVSSSIAASAASSSARESER
MAB_1885|M.abscessus_ATCC_1997 AICAAVVAGCTVATGGQASAPSESVSEYRTFVSQSVEASRSE----ESKR
* :.**: * * . .. ** *: : : *::*
Rv2240c|M.tuberculosis_H37Rv QQSLTTKAIRTSCDALAATSKDAIDKVNAYVAAFN----QGRNTGPTEGP
Mb2264c|M.bovis_AF2122/97 QQSLTTKAIRTSCDALAATSKDAIDKVNAYVAAFN----QGRNTGPTEGP
MMAR_3333|M.marinum_M QQSLTTKAIRTSCETLATTSKEAIDKVNEFVGAFN----AGRSTGPTEGP
MUL_1309|M.ulcerans_Agy99 QQSLTTKAIRTSCETLATTSKEAIDKVNEFVGAFN----AGRSTGPTEGP
MAV_2197|M.avium_104 QQSLTTKAVRTACAALVTTSKNAIDKTNEFVQAFN----SGRGTGPTEGP
Mflv_2782|M.gilvum_PYR-GCK QASLTVEAVRTSCEAMSSSSAEAVGSVNNYVDAMNN---SPADVARTAGP
Mvan_3751|M.vanbaalenii_PYR-1 QTSLTVEAVHTSCEALSSSSAEAIGAVNAYVDAFNE---NAADIERTAGP
MSMEG_4322|M.smegmatis_MC2_155 QATLTKRAIHTVCEDLSTSSVDAIDAVNTYIEAANN---NSPDVRAKAGP
TH_1340|M.thermoresistible__bu QRSLTRQAVHNSCDALSTSSVDAIRAVNAYVDAFN----STGDVGAKVRP
MAB_1885|M.abscessus_ATCC_1997 QETSRAQAQADACETFAMTSDAAVSAGNDLISVMNDEGGYGSSAEAKVGP
* : .* * : :* *: * : . * . . *
Rv2240c|M.tuberculosis_H37Rv AIDALNNSASTVSGSLSAALSAQLGDALNAYVDAARAVANAIGAHASTAE
Mb2264c|M.bovis_AF2122/97 AIDALNNSASTVSGSLSAALSAQLGDALNAYVDAARAVANAIGAHASTAE
MMAR_3333|M.marinum_M AIEALNNSASSVSSALNEALSPDMRDAFNAYTDAARAVANAIGTHAPTGE
MUL_1309|M.ulcerans_Agy99 AIEALNNSASSVSSALNEALSPDMRDAFNAYTDAVRSVANAIGTHAPTGE
MAV_2197|M.avium_104 AIDALNDSANTVANSFNDAMSQQIKDAFNAYIDAAHAVANAIGTHASTSE
Mflv_2782|M.gilvum_PYR-GCK AVDALNHSADLVAGSLSDPLTSELRDALNGWVDAARGVATAIAGNYGIDA
Mvan_3751|M.vanbaalenii_PYR-1 AVDALNHSADLVAGSISDPLPAELRDALNSWVDAARAVATAIAGNYPTDE
MSMEG_4322|M.smegmatis_MC2_155 AVDALNRSADLVTSGISDTLPADLRDALTEWVDAVRAVASAISGDASPDV
TH_1340|M.thermoresistible__bu AVDALNHSADLVQSSLSDALTPELRDALTAWTTAAREVGVAIEEDHPTDE
MAB_1885|M.abscessus_ATCC_1997 VINALNTSAGQIDSVKAKAQTDELRDALTQYVEQSRKLAGAFDNRLSSST
.::*** **. : . . . :: **:. : : :. *:
Rv2240c|M.tuberculosis_H37Rv FNRRVDRLNDTKTKALTMCVAAF-----
Mb2264c|M.bovis_AF2122/97 FNRRVDRLNDTKTKALKMCVAAF-----
MMAR_3333|M.marinum_M FNRRVDQLNDTKTKALKLCMASY-----
MUL_1309|M.ulcerans_Agy99 FNRRVDQLNDTKTKALKLCMASY-----
MAV_2197|M.avium_104 FNKRVDQLNDTKKKAIQLCLAT------
Mflv_2782|M.gilvum_PYR-GCK FNAAIEVLNRAKTTALDRCDAAYR----
Mvan_3751|M.vanbaalenii_PYR-1 FNAAISRLNDSKTTALDRCDAAYR----
MSMEG_4322|M.smegmatis_MC2_155 FNAASDRSNSARTAALDRCDAAY-----
TH_1340|M.thermoresistible__bu FNAGVDRLNQSRALALTLCDAAY-----
MAB_1885|M.abscessus_ATCC_1997 LNAVVRTFNDARERAGKICEPLLQTKGR
:* * :: * * .