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MSPKLSPPNIGEVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEIALYSFVVLLITGVYLTLFFD PSMVDVTYNGVYQPLRGVEMSRAYQSALDISFEVRGGLFVRQIHHWAALMFAAAIMVHLARIFFTGAFRR PRETNWVIGSLLLILAMFEGYFGYSLPDDLLSGLGLRAALSSITLGMPVIGTWLHWALFGGDFPGTILIP RLYALHILLLPGIILALIGLHLALVWFQKHTQFPGPGRTEHNVVGVRVMPVFAFKSGAFFAAIVGVLGLM GGLLQINPIWNLGPYKPSQVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAVIMGLVFVLLP AYPFLEKRFTGDYAHHNLLQRPRDVPVRTAIGAMAIAFYMVLTLAAMNDIIALKFHISLNATTWIGRIGM VILPPFVYFITYRWCIGLQRSDRSVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPIPLQYQGAPLP KRMNKLGSAGSPGSGSFLFADSAAEDAALREAGHAAEQRALAALREHQDSIMGSPDGEH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2196 | qcrB | - | 100% (549) | Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2219 | qcrB | 0.0 | 100.00% (549) | ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) |
| M. gilvum PYR-GCK | Mflv_2953 | - | 0.0 | 80.55% (550) | cytochrome b/b6 domain-containing protein |
| M. leprae Br4923 | MLBr_00879 | qcrB | 0.0 | 92.52% (548) | putative cytochrome B |
| M. abscessus ATCC 19977 | MAB_1966c | - | 0.0 | 78.29% (525) | ubiquinol-cytochrome c reductase cytochrome b subunit |
| M. marinum M | MMAR_3240 | qcrB | 0.0 | 88.89% (558) | ubiquinol-cytochrome C reductase QcrB |
| M. avium 104 | MAV_2296 | - | 0.0 | 88.69% (557) | cytochrome b6 |
| M. smegmatis MC2 155 | MSMEG_4263 | - | 0.0 | 82.17% (544) | ubiquinol-cytochrome c reductase cytochrome b subunit |
| M. thermoresistible (build 8) | TH_1044 | qcrB | 0.0 | 78.87% (549) | Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B |
| M. ulcerans Agy99 | MUL_3553 | qcrB | 0.0 | 88.89% (558) | ubiquinol-cytochrome C reductase QcrB |
| M. vanbaalenii PYR-1 | Mvan_3560 | - | 0.0 | 80.62% (552) | cytochrome b/b6 domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2953|M.gilvum_PYR-GCK MSPR---LDAATVAAKQGDAIDSRYHPSAAVRRQLNKVFPTHWSFLLGEI
Mvan_3560|M.vanbaalenii_PYR-1 MSPR---PTAAEIAARQGNAIDSRYHPSAAVRRQLNKVFPTHWSFLLGEI
MSMEG_4263|M.smegmatis_MC2_155 MSP-----DFAKLAAAQGDAIDSRYHPSAAVRRQLNKVFPTHWSFLLGEI
Rv2196|M.tuberculosis_H37Rv MSPKLSPPNIGEVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEI
Mb2219|M.bovis_AF2122/97 MSPKLSPPNIGEVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEI
MLBr_00879|M.leprae_Br4923 MSPK-SVPDIGDVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEI
MMAR_3240|M.marinum_M MSPKLSPPKIGDVLARQAEDIDTRYHPAAALRRQFNKVFPTHWSFLLGEV
MUL_3553|M.ulcerans_Agy99 MSPKLSPPKIGDVLARQAEDIDTRYHPAAALRRQFNKVFPTHWSFLLGEV
MAV_2296|M.avium_104 MSPKLSPPKIGDVLARQGEDIDTRYHPSAAVRRQLNKVFPTHWSFLLGEI
TH_1044|M.thermoresistible__bu MSPK-----LAEIAAKQGEAIDSRYHPSAAVRRQLNKVFPTHWSFLLGEI
MAB_1966c|M.abscessus_ATCC_199 MSDT---AQKPSRAAKQAEAMDSRYHLAAGMKRQINKVFPTHWSFMLGEI
** * *.: :*:*** :*.::**:**********:***:
Mflv_2953|M.gilvum_PYR-GCK AMYSFIVLLLTGVYLTLFFDPSMAHVTYDGVYQPLRGVGMSRAYETTLDI
Mvan_3560|M.vanbaalenii_PYR-1 AMYSFIVLLLTGVWLTLFFDPSMAHVTYDGVYQPLRGVGMSRAYETTLDI
MSMEG_4263|M.smegmatis_MC2_155 ALYSFIILLLTGVWLTLFFDPSMAHVTYDGVYQPLRGVQMSRAYETALDI
Rv2196|M.tuberculosis_H37Rv ALYSFVVLLITGVYLTLFFDPSMVDVTYNGVYQPLRGVEMSRAYQSALDI
Mb2219|M.bovis_AF2122/97 ALYSFVVLLITGVYLTLFFDPSMVDVTYNGVYQPLRGVEMSRAYQSALDI
MLBr_00879|M.leprae_Br4923 ALYSFIVLLLTGVYLTLFFDPSMTDVTYNGVYQPLRGVEMSRAYQSTLDI
MMAR_3240|M.marinum_M ALYSFIVLLITGVYLTLFFDPSMMDVTYNGVYQPLRGVEMSKAYASALDI
MUL_3553|M.ulcerans_Agy99 ALYSFIVLLITGVYLTLFFDPSMMDVTYNGVYQPLRGVEMSKAYASALDI
MAV_2296|M.avium_104 AMYSFIVLLLTGVYLTLFFDPSMAEVTYNGVYQPLRGVEMSKAFASALDI
TH_1044|M.thermoresistible__bu ALYSFIVLIITGIYLTLFFDPSMAHVVYDGVYQPLRGVEMSRAYETALNI
MAB_1966c|M.abscessus_ATCC_199 ALYSFIVLLLSGVYLTLFFDPSMSEVTYNGIYQPLRGVQMSKAYETTLNI
*:***::*:::*::********* .*.*:*:******* **:*: ::*:*
Mflv_2953|M.gilvum_PYR-GCK SFEVRGGLFVRQVHHWAALLFAASIMVHLARIFFTGAFRRPREANWVIGS
Mvan_3560|M.vanbaalenii_PYR-1 SFEVRGGLFVRQVHHWAALLFAASIMVHLARIFFTGAFRRPREANWVIGS
MSMEG_4263|M.smegmatis_MC2_155 SFEVRGGLFVRQVHHWAALMFAASIMVHLARIFFTGAFRRPREANWVIGS
Rv2196|M.tuberculosis_H37Rv SFEVRGGLFVRQIHHWAALMFAAAIMVHLARIFFTGAFRRPRETNWVIGS
Mb2219|M.bovis_AF2122/97 SFEVRGGLFVRQIHHWAALMFAAAIMVHLARIFFTGAFRRPRETNWVIGS
MLBr_00879|M.leprae_Br4923 SFEVRGGLFVRQIHHWAALMFTAAIMVHLARIFFTGAFRRPRETNWVIGS
MMAR_3240|M.marinum_M SFEVRGGLFVRQVHHWAALMFAAAIMVHLARIFFTGAFRRPREANWIIGS
MUL_3553|M.ulcerans_Agy99 SFEVRGGLFVRQVHHWAALMFAAAIMVHLARIFFTGAFRRPREANWIIGS
MAV_2296|M.avium_104 SFEVRGGLFVRQVHHWAALIFSAAIMVHLARIFFTGAFRRPREANWVIGS
TH_1044|M.thermoresistible__bu SFEVRGGLFVRQIHHWAALLFAAAIMVHLARVFFTGAFRRPREANWVIGC
MAB_1966c|M.abscessus_ATCC_199 SFEVRGGLFVRQIHHWAALMFAASIMVHMARIFFTGAFRRPREANWVIGA
************:******:*:*:****:**:***********:**:**.
Mflv_2953|M.gilvum_PYR-GCK LLLILAMFEGFFGYSLPDDLLSGTGIRAALSGITMGIPVVGTWMHWALFG
Mvan_3560|M.vanbaalenii_PYR-1 LLLILAMFEGFFGYSLPDDLLSGTGIRAALSGITMGIPIVGTWMHWALFG
MSMEG_4263|M.smegmatis_MC2_155 LLLILAMFEGFFGYSLPDDLLSGTGIRAALSGITMGIPVIGTWMHWALFG
Rv2196|M.tuberculosis_H37Rv LLLILAMFEGYFGYSLPDDLLSGLGLRAALSSITLGMPVIGTWLHWALFG
Mb2219|M.bovis_AF2122/97 LLLILAMFEGYFGYSLPDDLLSGLGLRAALSSITLGMPVIGTWLHWALFG
MLBr_00879|M.leprae_Br4923 LLLILAMFEGYFGYSMPDDLLSGIGLRAALSSITLGIPVIGTWLHWALFG
MMAR_3240|M.marinum_M LLLILAMFEGYFGYSLPDDLLSGIGLRAALSSITLGMPVIGTWLHWALFG
MUL_3553|M.ulcerans_Agy99 LLLILAMFEGYFGYSLPDDLLSGIGLRAALSSITLGMPVIGTWLHWALFG
MAV_2296|M.avium_104 LLLILAMFEGYFGYSLPDDLLSGIGLRAALSSITLGMPVIGTWLHWALFG
TH_1044|M.thermoresistible__bu LLLILAMFEGFFGYTLPDELLSGTGLRASFSSITLGMPVIGTWLHWMLFG
MAB_1966c|M.abscessus_ATCC_199 LLFILAMFEGFFGYSLPDDLLSGTGIRAALSGITMGLPLIGTWMHWALFG
**:*******:***::**:**** *:**::*.**:*:*::***:** ***
Mflv_2953|M.gilvum_PYR-GCK GDFPG----------EILIPRLYALHILLIPGIILALIGVHLALVWFQKH
Mvan_3560|M.vanbaalenii_PYR-1 GDFPG----------DILIPRLYALHILLIPGIILALIGVHLALVWFQKH
MSMEG_4263|M.smegmatis_MC2_155 GDFPG----------EILIPRLYALHILLIPGIILALIGAHLALVWFQKH
Rv2196|M.tuberculosis_H37Rv GDFPG----------TILIPRLYALHILLLPGIILALIGLHLALVWFQKH
Mb2219|M.bovis_AF2122/97 GDFPG----------TILIPRLYALHILLLPGIILALIGLHLALVWFQKH
MLBr_00879|M.leprae_Br4923 GDFPG----------TILIPRLYALHILLIPGVILALIGLHLALVWFQKH
MMAR_3240|M.marinum_M GDFPCGGVGDDCTAAGYIIPRMYSLHILLLPGIILALIGMHMALVWFQKH
MUL_3553|M.ulcerans_Agy99 GDFPCGGVGDDCTAAGYIIPRMYSLHILLLPGIILALIGMHMALVWFQKH
MAV_2296|M.avium_104 GDFPCGGVGSECAAAGYIIPRMYALHILLLPGIILALIGLHLAMVWFQKH
TH_1044|M.thermoresistible__bu GDFPG----------NIIIPRMYALHILILPGIMLALVGAHLALVWFQKH
MAB_1966c|M.abscessus_ATCC_199 GDFPG----------NILIPRLYAMHILLIPAIILALIGIHLALVWYQKH
**** :***:*::***::*.::***:* *:*:**:***
Mflv_2953|M.gilvum_PYR-GCK TQFPGPGRTETNVVGVRVMPVFAVKSGAFFAVTVGILGLMGGLLQINPVW
Mvan_3560|M.vanbaalenii_PYR-1 TQFPGPGRTETNVVGVRVMPVFAVKSGAFFAMTVGVLGLMGGLLQINPVW
MSMEG_4263|M.smegmatis_MC2_155 TQFPGPGRTETNVVGVRVMPVFAVKSGAFFAMITGVLGLMGGLLTINPIW
Rv2196|M.tuberculosis_H37Rv TQFPGPGRTEHNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGLLQINPIW
Mb2219|M.bovis_AF2122/97 TQFPGPGRTEHNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGLLQINPIW
MLBr_00879|M.leprae_Br4923 TQFPGPGRTEYNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGFLQINPIW
MMAR_3240|M.marinum_M TQFPGPGRTEHNVVGVRVMPVFAVKSGAFFAAITGVLGLMGGLLQINPIW
MUL_3553|M.ulcerans_Agy99 TQFPGPGRTEHNVVGVRVMPVFAVKSGAFFAAITGVLGLMGGLLQINPIW
MAV_2296|M.avium_104 TQFPGPGRTEHNVVGVRVMPVFAVKSGAFFAAIVGVLGLMGGLLQINPIW
TH_1044|M.thermoresistible__bu TQFPGPGRTETNVVGVRVMPVFAVKSGAFFAMTVGVLGIMGGLLQINPIW
MAB_1966c|M.abscessus_ATCC_199 TQFPGPGATEKNVVGVRILPVFALKGGSFFAFTTAILALMSGLLQINPIW
******* ** ******::****.*.*:*** ..:*.:*.*:* ***:*
Mflv_2953|M.gilvum_PYR-GCK NIGPYNPSQVSAGSQPDFYMMWTDGLIRLWPAWEFYPFGHTIPQGVWVAL
Mvan_3560|M.vanbaalenii_PYR-1 TIGPYKPSQVSAGSQPDFYMMWTDGLIRLWPAWEFYPFGHTIPQGVWVAV
MSMEG_4263|M.smegmatis_MC2_155 NLGPYKPSQVSAGSQPDFYMMWTDGLIRLWPAWEFYPFGHTIPQGVWVAV
Rv2196|M.tuberculosis_H37Rv NLGPYKPSQVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAV
Mb2219|M.bovis_AF2122/97 NLGPYKPSQVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAV
MLBr_00879|M.leprae_Br4923 NLGPYKPSQVSAGSQPDFYMMWTEGLARIWPAWEFYFWHHTIPAPVWVAV
MMAR_3240|M.marinum_M NLGPYKPAHVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAL
MUL_3553|M.ulcerans_Agy99 NLGPYKPAHVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAL
MAV_2296|M.avium_104 NLGPYKPSHVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAVVWVAL
TH_1044|M.thermoresistible__bu NLGPYRPSQISAGSQPDFYMMWTEGMARIFPPWEIYIGNYTIPASTWVAL
MAB_1966c|M.abscessus_ATCC_199 VLGPYKPSQISAGSQPDFYMMWTDGLLRIIPAWEIYPFGHTIPQAVWVAV
:***.*:::*************:*: *: *.**:* :*** .***:
Mflv_2953|M.gilvum_PYR-GCK AMGLIFMLLGAYPFIEKKLTGDNAHHNLLQRPRDAPTRTAVGAAAIAFYI
Mvan_3560|M.vanbaalenii_PYR-1 GMGLIFTLLAAYPFIEKKLSGDDAHHNLLQRPRDAPTRTAVGAAAIAFYI
MSMEG_4263|M.smegmatis_MC2_155 GMGLVFALLIAYPFIEKKVTGDDAHHNLLQRPRDVPVRTAIGSMAIALYL
Rv2196|M.tuberculosis_H37Rv IMGLVFVLLPAYPFLEKRFTGDYAHHNLLQRPRDVPVRTAIGAMAIAFYM
Mb2219|M.bovis_AF2122/97 IMGLVFVLLPAYPFLEKRFTGDYAHHNLLQRPRDVPVRTAIGAMAIAFYM
MLBr_00879|M.leprae_Br4923 IMALVFVLLITYPFLEKRFTGDYAHHNLLQRPRDVPVRTSIGAMAITFYM
MMAR_3240|M.marinum_M IMGLIFMLLIVYPFLEKRFTGDYAHHNLLQRPRDAPVRTAVGAMAISFYM
MUL_3553|M.ulcerans_Agy99 IMGLIFMLLIVYPFLEKRFTGDYAHHNLLQRPRDAPVRTAVGAMAISFYM
MAV_2296|M.avium_104 IMGAVFVLLIIYPFLEKRFSGDYAHHNLLQRPRDVPVRTSIGAMAIAFYM
TH_1044|M.thermoresistible__bu AMAVVFIGLIVYPWVEKKLTGDDAHHNLLQRPRDVPVRTGIGAAAISFYL
MAB_1966c|M.abscessus_ATCC_199 GMGLVFGLLIAYPFLEKKLTGDDAHHNLLQRPRDAPVRTAIGSAAISLYM
*. :* * **::**:.:** ***********.*.**.:*: **::*:
Mflv_2953|M.gilvum_PYR-GCK VLTFACMNDIIALKFHISLNATTWIGRVGMVLLPAIVYFVTYRWAVALQR
Mvan_3560|M.vanbaalenii_PYR-1 VLTFACMNDIIALKFHISLNATTWIGRVGMVVLPAIVYFVAYRWAVGLQR
MSMEG_4263|M.smegmatis_MC2_155 LLTFACMNDIIALKFHISLNATTWIGRIGMVVLPAIVYFVAYRWAISLQR
Rv2196|M.tuberculosis_H37Rv VLTLAAMNDIIALKFHISLNATTWIGRIGMVILPPFVYFITYRWCIGLQR
Mb2219|M.bovis_AF2122/97 VLTLAAMNDIIALKFHISLNATTWIGRIGMVILPPFVYFITYRWCIGLQR
MLBr_00879|M.leprae_Br4923 VLTLAAMNDIIALKFHISLNATTWIGRIGMVILPLLVYFITYRWCIGLQR
MMAR_3240|M.marinum_M LLTLAAMNDIIALKFHISLNATTWIGRIGMVILPPFVYFISYRWSIGLQR
MUL_3553|M.ulcerans_Agy99 LLTLAAMNDIIALKFHISLNATTWIGRIGMVILPPFVYFISYRWSIGLQR
MAV_2296|M.avium_104 VLTLSAMNDIIALKFDISLNATTWIGRIGMVIVPPIVYFVTYRWCIGLQR
TH_1044|M.thermoresistible__bu LMTLAAMNDVIAWKFHISLNATTWIGRIGMVVLPAIVYFVAYRWAVSLQR
MAB_1966c|M.abscessus_ATCC_199 LFTLMCMNDIIALKFHISLNATTWIGRIGMVILPAVVYYIAYRWAIGLQR
::*: .***:** **.***********:***::* .**:::***.:.***
Mflv_2953|M.gilvum_PYR-GCK SDRAVLEHGVETGIIKRLPHGAYVELHQPLGPVDDHGHPLPLEYQGAALP
Mvan_3560|M.vanbaalenii_PYR-1 SDRAVLEHGVETGIIKRLPHGAYVELHQPLGPVDEHGHPIPLEYQGAALP
MSMEG_4263|M.smegmatis_MC2_155 SDREVLEHGVETGIIKRLPHGAYVELHQPLGPVDEHGHPIPLEYAGAPLP
Rv2196|M.tuberculosis_H37Rv SDRSVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPIPLQYQGAPLP
Mb2219|M.bovis_AF2122/97 SDRSVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPIPLQYQGAPLP
MLBr_00879|M.leprae_Br4923 SDRAVLEHGIETGIIKRLPHGAYIELHQPLGPVDDHGHPIPLEYQGTAVP
MMAR_3240|M.marinum_M SDRAVLEHGIETGIIKRLPHGAYIELHQPLGPVDEHGHPLPLDYQGAPLP
MUL_3553|M.ulcerans_Agy99 SDRAVLEHGIETGIIKRLPHGAYIELHQPLGPVDEHGHPLPLDYQGAPLP
MAV_2296|M.avium_104 SDRAVLEHGIETGIIKRLPHGAYIELHQPLGPVDEHGHPLPLEYQGAPLP
TH_1044|M.thermoresistible__bu SDREVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPIPLEYQGAPVP
MAB_1966c|M.abscessus_ATCC_199 SDRAVLEHGIETGIIKRLPHGEYIEIHQPLAGVDEHGHAIPLEYQGAPVP
*** *****:*********** *:*:****. **:***.:**:* *:.:*
Mflv_2953|M.gilvum_PYR-GCK KRMNKLGSAGAPGSGSFLKADPLSEHEAIAEATHAAEHRALTALREHQER
Mvan_3560|M.vanbaalenii_PYR-1 KRMNKLGSAGAPGSGSFLKGDPLSEHEALDEAAHAAERRALTALREHQER
MSMEG_4263|M.smegmatis_MC2_155 KRMNKLGSGGAPGTGSFLFPDPAVEHEALTEAAHASEHKSLTALKEHQDR
Rv2196|M.tuberculosis_H37Rv KRMNKLGSAGSPGSGSFLFADSAAEDAALREAGHAAEQRALAALREHQDS
Mb2219|M.bovis_AF2122/97 KRMNKLGSAGSPGSGSFLFADSAAEDAALREAGHAAEQRALAALREHQDS
MLBr_00879|M.leprae_Br4923 KRMNKLGSAGSPSSGSFLFADPVSEDAALREATHVAEQRALTALREHQDS
MMAR_3240|M.marinum_M KRMNKLGSAGSPGSGSFLTADPASEDAALREAGHAAEHRALTALREYQDS
MUL_3553|M.ulcerans_Agy99 KRMNKLGSAGSPGSGSFLTADPASEDAALREAGHAAEHRALTALREYQDS
MAV_2296|M.avium_104 KKMNKLGSAGSPGIGSFLYADPPSEDAALREAAHASEQRALTALREHQDS
TH_1044|M.thermoresistible__bu KRMNKLGAGGVPGTGSFITPDPISEHEALVEAAHASERKALAALEEYQEN
MAB_1966c|M.abscessus_ATCC_199 QRMNKLGSAGAPGTGSFLFADPADEQHALAEAEHEAHHKSLLALKEYQDG
::*****:.* *. ***: *. *. *: ** * :.:::* **.*:*:
Mflv_2953|M.gilvum_PYR-GCK SSAPNGSSDGASNGS---SNGHH
Mvan_3560|M.vanbaalenii_PYR-1 TSA--------SNGS---SNGHH
MSMEG_4263|M.smegmatis_MC2_155 IHG---------NGE---TNGHH
Rv2196|M.tuberculosis_H37Rv IMG-------SPDG----EH---
Mb2219|M.bovis_AF2122/97 IMG-------SPDG----EH---
MLBr_00879|M.leprae_Br4923 IAS-------SPNG----ERGKH
MMAR_3240|M.marinum_M LNE-------TSNG-----EGDH
MUL_3553|M.ulcerans_Agy99 LNE-------TSNG-----EGDH
MAV_2296|M.avium_104 IVG-------STNGSTNGEDGQH
TH_1044|M.thermoresistible__bu LRDG------QGNG----EVARR
MAB_1966c|M.abscessus_ATCC_199 EPS--------TNG-----HGH-
:*