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LTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLIIAVAALLTTLG LIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPG IGKEANGSRGWFVVAGFSMQPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALIVAQPD LGQTVSMGIILLGLLWYAGLPLRVFLSSLAAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQA KFALAQGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPF LRLLTATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIANAARHEPEAVAALRA GRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGLPPRPGSPRTAD PPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2154c | ftsW | - | 100% (524) | FtsW-like protein FtsW |
| M. tuberculosis H37Rv | Rv0017c | rodA | 1e-41 | 32.23% (363) | cell division protein RodA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2178c | ftsW | 0.0 | 100.00% (524) | FtsW-like protein FtsW |
| M. gilvum PYR-GCK | Mflv_2987 | - | 0.0 | 73.20% (485) | cell division protein FtsW |
| M. leprae Br4923 | MLBr_00913 | ftsW | 0.0 | 75.47% (530) | putative cell division protein FtsW |
| M. abscessus ATCC 19977 | MAB_2005 | - | 0.0 | 69.05% (475) | putative cell division protein FtsW |
| M. marinum M | MMAR_3194 | ftsW | 0.0 | 79.41% (539) | FtsW-like protein FtsW |
| M. avium 104 | MAV_2335 | ftsW | 0.0 | 73.47% (539) | cell division protein FtsW |
| M. smegmatis MC2 155 | MSMEG_4228 | ftsW | 0.0 | 66.32% (570) | cell division protein FtsW |
| M. thermoresistible (build 8) | TH_1478 | ftsW | 0.0 | 65.28% (553) | cell division protein FtsW |
| M. ulcerans Agy99 | MUL_3502 | ftsW | 0.0 | 78.29% (539) | FtsW-like protein FtsW |
| M. vanbaalenii PYR-1 | Mvan_3524 | - | 0.0 | 70.96% (513) | cell division protein FtsW |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2154c|M.tuberculosis_H37Rv ---MLTRLLRRGTSDTD--------------GSQTRGAEPVE--------
Mb2178c|M.bovis_AF2122/97 ---MLTRLLRRGTSDTD--------------GSQTRGAEPVE--------
MMAR_3194|M.marinum_M MASALTRLLRRGKTDTDNADLQADTDPEIADSADSAAEQPVA--------
MUL_3502|M.ulcerans_Agy99 MASALTWLLRRGKTDTENADLQTDTDPEVADSADSAAEQPVA--------
MLBr_00913|M.leprae_Br4923 MGNALGRDRGRGTGDNNSVQ------AATTVEAVEPGTATTG--------
MAV_2335|M.avium_104 MGNALTRLLGRGKDTTKTAEPADDDGAAADTGAVPDGAPEADDEQDQQVT
Mflv_2987|M.gilvum_PYR-GCK MSNILSRLRHRRAN-----------------PAADTGTTVTS--------
Mvan_3524|M.vanbaalenii_PYR-1 MSSILSRLRNRRAN-----------------PAADP-QAVTG--------
MSMEG_4228|M.smegmatis_MC2_155 MGSILTRLRRGGAPGDAPEDAS-------KDTADDASKDAQT--------
TH_1478|M.thermoresistible__bu VSAILDRLRHRRTSPAADDSASE---PGEREASGPAGEAGAG--------
MAB_2005|M.abscessus_ATCC_1997 MSTLTAPFARIFRSEKR--------------DEAKTSVTSVK--------
Rv2154c|M.tuberculosis_H37Rv -----GQRTGPEEASNPGSAR--------------PRTRFGAWLGRPMTS
Mb2178c|M.bovis_AF2122/97 -----GQRTGPEEASNPGSAR--------------PRTRFGAWLGRPMTS
MMAR_3194|M.marinum_M -----ADASAKAAKGQTNSEERG------------PRTRFGAWLGRPMTS
MUL_3502|M.ulcerans_Agy99 -----ADASDKAAKGQTNSEERG------------LRTRFGAWLGRPMTS
MLBr_00913|M.leprae_Br4923 ----EVSEAEAKRAG---SLRAGVRGPQ---------TRFDAWLGRPMAS
MAV_2335|M.avium_104 DEPTKASQKASKKASTKASKKESKKAPKDKPKDGSSHSRFGAWLSRPMTS
Mflv_2987|M.gilvum_PYR-GCK -------GAAATSDAVLRLPR----------------TRVGAWLGRPMTS
Mvan_3524|M.vanbaalenii_PYR-1 -------GKAASDG--LHLPR----------------TRVGAWLGRPMTS
MSMEG_4228|M.smegmatis_MC2_155 -------GTPEAGQSETKVPR----------------TRFGTWLGRPMTS
TH_1478|M.thermoresistible__bu -------STGRPAGTAITGVR----------------TRISAWIGRPMTS
MAB_2005|M.abscessus_ATCC_1997 -------KSGAKNDGLIAR------------------TRLGAWLNRPMTS
:*..:*:.***:*
Rv2154c|M.tuberculosis_H37Rv FHLIIAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLI
Mb2178c|M.bovis_AF2122/97 FHLIIAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLI
MMAR_3194|M.marinum_M FHLIIAVAALLTTLGLIMVLSASGVRSYDDDGSAWVIFGKQVLWTGVGLV
MUL_3502|M.ulcerans_Agy99 FHLIIAVAALLTTLGLIMVLSASGVRSYDDDGSAWVIFGKQVLWTGVGLV
MLBr_00913|M.leprae_Br4923 FHLIIAVAGLLTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLI
MAV_2335|M.avium_104 FHLIIAIAGLLTTLGLIMVLSASGVRSYDADGSAWVIFGKQVLWTVIGLI
Mflv_2987|M.gilvum_PYR-GCK FHLIVAVTALLITMGLTMVLSASGVYSYDQDGSPWSVFTKQVLWTVIGLF
Mvan_3524|M.vanbaalenii_PYR-1 FHLIVAVTALLITMGLTMVLSASGVYSYDFEGSPWAVFGKQVLWTAIGLL
MSMEG_4228|M.smegmatis_MC2_155 FHLIIAVTALLTTLGLIMVLSASGVYSYDSDGSPWAVFGRQVLWTAIGLV
TH_1478|M.thermoresistible__bu FHLIIAVTALLTLLGLTMVLSASGVRSYGDDGSPWAIFSRQVLWTLIGLV
MAB_2005|M.abscessus_ATCC_1997 FHLVVATAALLTTLGLIMVLSASGVESYYDDGSAWTIFGKQVLWVCVGLV
***::* :.** :** ******.* ** :**.* :* :****. :**.
Rv2154c|M.tuberculosis_H37Rv GGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVA
Mb2178c|M.bovis_AF2122/97 GGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVA
MMAR_3194|M.marinum_M GCYVGLRMSVSFLRRIAFSGFAFTIVLLVLVLIPGIGKEANGSRGWFVVA
MUL_3502|M.ulcerans_Agy99 GCYGGLRMSVSFLRRIAFSGFAFTIVLLVLVLIPGIGKEANGSRGWIVVA
MLBr_00913|M.leprae_Br4923 GGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLANGSRKWFVIA
MAV_2335|M.avium_104 ACYASLRMSVRFIRRVAFTGYVVTVILLVLVLVPGIGNLANGSRKWFVVA
Mflv_2987|M.gilvum_PYR-GCK AFYVALRTPVAVMRRFAFTGFAFSIVLLVLVLIPGIGKVANGSRGWFVVA
Mvan_3524|M.vanbaalenii_PYR-1 AFYVALRMPVAVMRRFAFAGFAFSVVLLILVLIPGIGKVANGSRGWFVVA
MSMEG_4228|M.smegmatis_MC2_155 AFYFALRIRVATLRKLAFPGFAVTIVLLVLVLIPGIGKVANGSRGWFVVA
TH_1478|M.thermoresistible__bu AFYVAVRTRIRVLRRFAFAGYLVTIVLLILVLIPGIGTVANGSRGWFVFG
MAB_2005|M.abscessus_ATCC_1997 GFYIALRTPVAVMRRYSFPVFVFTVILITLVLIPGIGTYSNGSRGWFVYA
. * : : :*: :* : .::::: ***:****. :**** *:* .
Rv2154c|M.tuberculosis_H37Rv GFSMQPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALI
Mb2178c|M.bovis_AF2122/97 GFSMQPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALI
MMAR_3194|M.marinum_M GFSMQPSELTKMAFAVWGAHLLATRRMERASLREMLIPLVPAAVIALALI
MUL_3502|M.ulcerans_Agy99 GFSMQPSELTKMAFAVWGAHLLATRRMERASLREMLIPLVPAAVIALALI
MLBr_00913|M.leprae_Br4923 GFSMQPSELAKIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLI
MAV_2335|M.avium_104 GFSMQPSELAKIAFAIWGAHMLAARRLDRASLRELLIPLVPAAVIALALI
Mflv_2987|M.gilvum_PYR-GCK GFSMQPSELAKIALAIWGAHLLAARRMEHASLREMLVPLVPAAVIALALI
Mvan_3524|M.vanbaalenii_PYR-1 GFSMQPSELAKIAFAIWGAHLLAARRMEHASLREMLVPLVPAAVIALGLI
MSMEG_4228|M.smegmatis_MC2_155 GFSMQPSELAKIAFAIWGAHLLAARRMERASLREMLIPLVPAAVIALALI
TH_1478|M.thermoresistible__bu SLSMQPSEVAKISLALWGAHLLAARRMERASLREMLIPLVPATVVALALI
MAB_2005|M.abscessus_ATCC_1997 GLSMQPSELTKVAFAIWGAHLLASRRMEQASMREMLVPLVPAALIALVLI
.:******::*:::.:****:**:**:::**:**:*:*****:::** **
Rv2154c|M.tuberculosis_H37Rv VAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSLAAVVVSAAILAVSAGY
Mb2178c|M.bovis_AF2122/97 VAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSLAAVVVSAAILAVSAGY
MMAR_3194|M.marinum_M VAQPDLGQTVSMGIILLGLLWYAGLPLRVFMSSFAAVVVSAGVLAMTAGY
MUL_3502|M.ulcerans_Agy99 VAQPDLGQTVSMGIILLGLLWYAGLPLRVFMSSFAAVVVSAGVLAMTAGY
MLBr_00913|M.leprae_Br4923 VAQPDLGQTVSLGIILLALLWYAGLPLRVFITSLLAVFIAGAILAMSAGY
MAV_2335|M.avium_104 VAQPDLGQTVSLGIILLALLWYAGLPLRVFITSLLAVFMAGAVLAMSAGY
Mflv_2987|M.gilvum_PYR-GCK VLQPDLGQTLSMGVILLGLLWYAGLPLRVFLTSLGAVLVSGVILALAEGY
Mvan_3524|M.vanbaalenii_PYR-1 VSQPDLGQTLSMGVILLGLLWYAGLPLRVFLSSLGAVLISGAVLAMSAGY
MSMEG_4228|M.smegmatis_MC2_155 VAQPDLGQTVSLGIILLGLLWYAGLPLKVFVSSLFAVVASAIVLAFAEGY
TH_1478|M.thermoresistible__bu AAQPDLGHTVSLGIILLALLWYAGLPLRVFVSSLVAIVAAAAVLAMAEGY
MAB_2005|M.abscessus_ATCC_1997 VIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAAVLAAAILAVSAGY
. *****:*:*:.:***.*********:**::*. * . :. :**.: **
Rv2154c|M.tuberculosis_H37Rv RSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLP
Mb2178c|M.bovis_AF2122/97 RSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLP
MMAR_3194|M.marinum_M RSDRVRSWLDPDNDPQDSGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
MUL_3502|M.ulcerans_Agy99 RSDRVRSWLDPDNDPQDSGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
MLBr_00913|M.leprae_Br4923 RSERVRSWMNPEADPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
MAV_2335|M.avium_104 RSDRVRSWMNPENDPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
Mflv_2987|M.gilvum_PYR-GCK RSARVQSWLNPTADAQGSGYQGRQARYALANGGFFGDGLGQSTAKWNYLP
Mvan_3524|M.vanbaalenii_PYR-1 RSARVQSWLDPAADAQGSGYQARQARFALANGGVFGDGLGQGTAKWNYLP
MSMEG_4228|M.smegmatis_MC2_155 RSDRVQSWLNPGADTQGSGYQARQARFALANGGVFGDGLGQGTAKWNYLP
TH_1478|M.thermoresistible__bu RSVRVQSWLNPNADPQGAGYQARQARFALANGGFFGEGLGQGTAKWNYLP
MAB_2005|M.abscessus_ATCC_1997 RSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWHYLP
** **::*::* *.* :***.***::***:**.**:****. ***:***
Rv2154c|M.tuberculosis_H37Rv NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLT
Mb2178c|M.bovis_AF2122/97 NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLT
MMAR_3194|M.marinum_M NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLT
MUL_3502|M.ulcerans_Agy99 NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLT
MLBr_00913|M.leprae_Br4923 NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLT
MAV_2335|M.avium_104 NAHNDFIFAIIGEELGFIGAFGLLVLFGLFAYTGMRIARRSADPFLRLLT
Mflv_2987|M.gilvum_PYR-GCK NAHNDFIFAIIGEELGFVGAVGLLLLFGLFAYTGMRIARRSADPFLRLLT
Mvan_3524|M.vanbaalenii_PYR-1 NAHNDFIFAIIGEELGFVGAVGLLLLFGLFAYTGMRIARRSADPFLRLLT
MSMEG_4228|M.smegmatis_MC2_155 NAHNDFIFAIIGEELGLIGATGLLALFGLFAYTGMRIARRSVDPFLRLLS
TH_1478|M.thermoresistible__bu EAHNDFIFAIIGEELGFVGAMAVLCLFGLFAYTGMRIARRSVDPFLRLFT
MAB_2005|M.abscessus_ATCC_1997 NAHNDFIFAIIGEELGFVGCIGVLALFGVFAYTAMRIARRSADPFLRMIT
:***************::*. .:* ***:****.**** **.*****:::
Rv2154c|M.tuberculosis_H37Rv ATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIA
Mb2178c|M.bovis_AF2122/97 ATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIA
MMAR_3194|M.marinum_M ATVTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTATTLAMIGIIA
MUL_3502|M.ulcerans_Agy99 ATVTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTATTLAMIGIIA
MLBr_00913|M.leprae_Br4923 ATTTMWVLGQAFINIGYVIGVLPVTGLQLPFISAGGTSAAAILFMIGIMA
MAV_2335|M.avium_104 ATTTMWVLGQAFINIGYVIGILPVTGIQLPLISAGGTSTAATLFMIGIMA
Mflv_2987|M.gilvum_PYR-GCK ATATLWILSQVFINVGYVVGLLPVTGLQLPLISSGGTSTATTLLMIGIMA
Mvan_3524|M.vanbaalenii_PYR-1 ATATLWILSQVFINVGYVVGLLPVTGLQLPLISAGGTSTATTLLMIGIMA
MSMEG_4228|M.smegmatis_MC2_155 ATTTLWLIGQMFINVGYVVGLLPVTGLQLPLISAGGSSQATTLLMMGLLT
TH_1478|M.thermoresistible__bu ATATMWLLSQVFINVGYVVGLLPVTGLQLPLISAGGTASVTTLFMMGLIA
MAB_2005|M.abscessus_ATCC_1997 ATAGLWMIGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIGLIA
**. :*::.* ***:***:*:*****:***:**:**:: .: * ::*:::
Rv2154c|M.tuberculosis_H37Rv NAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQ
Mb2178c|M.bovis_AF2122/97 NAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQ
MMAR_3194|M.marinum_M NAARHEPEAVAALRAGRDDRVNRMLRLPLPKPYAPTRLEVFRDRKRVQPP
MUL_3502|M.ulcerans_Agy99 NAARHEPEAVAALRAGRDDRVNRMLRLPLPKPYAPTRLEVFRDRKRVQPP
MLBr_00913|M.leprae_Br4923 NAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQ
MAV_2335|M.avium_104 NAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYSPTRLEAFRDRKRTGPQ
Mflv_2987|M.gilvum_PYR-GCK NAARHEPEAVAALRAGRDDRVNRILRLPLPAPYVPSRTEALRDRLR----
Mvan_3524|M.vanbaalenii_PYR-1 NAARHEPEAVAALRAGRDDRVNRLLRLPLPAPYVPTRTEALRDRLR----
MSMEG_4228|M.smegmatis_MC2_155 NAARHEPDAVAALRAGRDDRVDRLLRLPLPEPYVPPRLDLVRERLSAKKA
TH_1478|M.thermoresistible__bu NAARHEPEAVAALRAGRDDRVNRWLRLPLPEPYAPTRLEAARDRLR----
MAB_2005|M.abscessus_ATCC_1997 NAARHEPEAVAALRAGSGDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSA
*******:******** .*:::: ****** ** *.* : *:*
Rv2154c|M.tuberculosis_H37Rv --------------PAQTQPARKTPRTAPGQPAR-------QMGLPPRPG
Mb2178c|M.bovis_AF2122/97 --------------PAQTQPARKTPRTAPGQPAR-------QMGLPPRPG
MMAR_3194|M.marinum_M --------------AARPPAKQAAARKAPKAATR-------LAEEPLRPA
MUL_3502|M.ulcerans_Agy99 --------------AARPPAKQAAARKAPKAATR-------LAEEPLRPA
MLBr_00913|M.leprae_Br4923 --------------PGKASVGRKPARKAPREPDR-----------PLRPA
MAV_2335|M.avium_104 QAPKSAPKSRPAPRKGAKPAGRKPTRNAGRNATRNAG---FHADAPLPPP
Mflv_2987|M.gilvum_PYR-GCK ----------------TKPEKKKAGKRPEKKPARAR--------------
Mvan_3524|M.vanbaalenii_PYR-1 ----------------KRP--RTPAPKAAERPQRRS--------------
MSMEG_4228|M.smegmatis_MC2_155 SG------------SATRPAKAKAKPKAAPRSAKAKPDARARTRATAGRV
TH_1478|M.thermoresistible__bu ----------------SRPGRQRGSKQAPRQTARTRRAAVRTGHPADRPA
MAB_2005|M.abscessus_ATCC_1997 ---------------AQSAAAARPQPERKRQSASAP--------GPKRTP
.
Rv2154c|M.tuberculosis_H37Rv SPRTADPPVRRSV-----------------------HHG----------A
Mb2178c|M.bovis_AF2122/97 SPRTADPPVRRSV-----------------------HHG----------A
MMAR_3194|M.marinum_M LPRRPDRPGARSG-----------------------QQG----------A
MUL_3502|M.ulcerans_Agy99 LPRRPDRSGARSG-----------------------QQG----------A
MLBr_00913|M.leprae_Br4923 FPRVADRLEHRSG-----------------------QYR----------A
MAV_2335|M.avium_104 LPRTAGRAGRQSGGNTRARARH---------HGSGQRYASLGANSGANPA
Mflv_2987|M.gilvum_PYR-GCK --------AAQSAR----------------------HPVRSGRS-----S
Mvan_3524|M.vanbaalenii_PYR-1 --------GRAAAG----------------------HPVRSGRS-----S
MSMEG_4228|M.smegmatis_MC2_155 AGRANSRTGAQTARTAGKTTRAGHRTADPGARRRSQQPGSSRRS-----A
TH_1478|M.thermoresistible__bu RRSGHHGGGRRSGG-------------------RVRQDRTARRSG----A
MAB_2005|M.abscessus_ATCC_1997 RARTDNEAGHHRQV----------------------QQARRG-------S
: :
Rv2154c|M.tuberculosis_H37Rv GQRYAGQR-RTRRVRALEGQRYG
Mb2178c|M.bovis_AF2122/97 GQRYAGQR-RTRRVRALEGQRYG
MMAR_3194|M.marinum_M GQRYAGQR-HSGRVRALEGQRYG
MUL_3502|M.ulcerans_Agy99 GQRYAGQR-HSGRVRALEGQRYG
MLBr_00913|M.leprae_Br4923 GQLRAGQR-YTPRVRVFEGQRYG
MAV_2335|M.avium_104 ASSRAGQR-QPRRARALEGQRYG
Mflv_2987|M.gilvum_PYR-GCK DGYGDGRRNQGRRARTMEGQRYG
Mvan_3524|M.vanbaalenii_PYR-1 GGYGDTRRNQGRRARTLEGQRYG
MSMEG_4228|M.smegmatis_MC2_155 VRYGADQQSQGHRARALEGQRYG
TH_1478|M.thermoresistible__bu ARSGAGQRQQGRRARALEGRRQG
MAB_2005|M.abscessus_ATCC_1997 ATRASGRSRDQSRTAGSRARSYR
: *. ..: