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AADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQ EASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEH RRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEH NRVRAMFPHAIGLSAGMSNDLEVAVKHGSTCVRVGTALLGPRRLRSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2148c | - | - | 100% (258) | hypothetical protein Rv2148c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2172c | - | 1e-145 | 100.00% (258) | hypothetical protein Mb2172c |
| M. gilvum PYR-GCK | Mflv_2993 | - | 2e-75 | 57.43% (249) | alanine racemase domain-containing protein |
| M. leprae Br4923 | MLBr_00919 | - | 1e-104 | 73.64% (258) | putative DNA-binding protein |
| M. abscessus ATCC 19977 | MAB_2011 | - | 1e-75 | 59.11% (247) | hypothetical protein MAB_2011 |
| M. marinum M | MMAR_3188 | - | 1e-107 | 74.03% (258) | hypothetical protein MMAR_3188 |
| M. avium 104 | MAV_2342 | - | 2e-97 | 72.29% (249) | hypothetical protein MAV_2342 |
| M. smegmatis MC2 155 | MSMEG_4220 | - | 3e-80 | 60.24% (249) | hypothetical protein MSMEG_4220 |
| M. thermoresistible (build 8) | TH_2376 | - | 8e-83 | 65.16% (244) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3496 | - | 1e-107 | 74.03% (258) | hypothetical protein MUL_3496 |
| M. vanbaalenii PYR-1 | Mvan_3518 | - | 2e-77 | 59.27% (248) | alanine racemase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2148c|M.tuberculosis_H37Rv -----------MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGE
Mb2172c|M.bovis_AF2122/97 -----------MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGE
MMAR_3188|M.marinum_M --------MTAMVVDISAQGERQSELTHALAVVRSRLAAAAEAAGRKVSE
MUL_3496|M.ulcerans_Agy99 -----------MVVDISAQGERQSELTHALALVRSRLAAAAEAAGRKVSE
MLBr_00919|M.leprae_Br4923 --------MTAMAADIDLQGDRESELMHALATVRSRLAAASQAAGRNVGE
MAV_2342|M.avium_104 --------MTAGTPAPDSAGDRETELTHALAAVRSRLAAAAEAAGRNVAE
Mflv_2993|M.gilvum_PYR-GCK -----------------MTSEREAELRAALDALRVRLARAAESAGRDVAE
Mvan_3518|M.vanbaalenii_PYR-1 -----------------MTAARDAELSLALTALRLRVARAAEAAGRDAGD
MSMEG_4220|M.smegmatis_MC2_155 MDGAGLAMSATTPSRRIRDADRTAQLTAALGAARARLARAAESAGRNVGE
TH_2376|M.thermoresistible__bu -------------------------LAVALAALRARLEQAAVAAGRAADE
MAB_2011|M.abscessus_ATCC_1997 -------------------MTRAEELSAALCSVRERVRRAAEIAGRDPGE
* ** * *: *: *** :
Rv2148c|M.tuberculosis_H37Rv IELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELNRLLAAAEL
Mb2172c|M.bovis_AF2122/97 IELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELNRLLAAAEL
MMAR_3188|M.marinum_M IELLPITKFFPATDVAILARLGCRAVGESRDQEASAKVAELARLFSAPIR
MUL_3496|M.ulcerans_Agy99 IELLPITKFFPATDVAILARLGCRAVGESRDQEASAKVAELARMFSAPMR
MLBr_00919|M.leprae_Br4923 IELLPISKFFPATDVAILSRLGCRSVGESRAQEASTKAAEFAELLGVSRE
MAV_2342|M.avium_104 IEVLPVTKFFPATDVVTLSRLGCRAVGESRDQEATAKVAEVTRLLATSAR
Mflv_2993|M.gilvum_PYR-GCK IELLPVIKFFPASDVLALYRLGCDAFAESRDQEATAKIEDVAR-VVGS--
Mvan_3518|M.vanbaalenii_PYR-1 IELLPVTKFFPASDVVALHRLGCSAFGESRDQEAAAKVEEVGG-LVG---
MSMEG_4220|M.smegmatis_MC2_155 IELLPVTKFFPGSDIVILNQLGCLSFGESREQEAANKIAEVR----AE--
TH_2376|M.thermoresistible__bu IELLPITKFFPASDVLILHGLGISAFGESREQEASAKIAEVNRNLSVE--
MAB_2011|M.abscessus_ATCC_1997 IQLLPVTKFFPASDVEELYRLGCREFGESRDQEAAAKVALLDQ-------
*::**: ****.:*: * ** ..*** ***: * .
Rv2148c|M.tuberculosis_H37Rv GHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALA
Mb2172c|M.bovis_AF2122/97 GHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALA
MMAR_3188|M.marinum_M SGSRGIQWHMVGQIQRNKVRSLANWAHTAHSIDTPQLVTALDRAITTAIA
MUL_3496|M.ulcerans_Agy99 SGSRGIQWHMVGQIQRNKVRSLANWAHTAHSIDTPQLVTALDRAITTAIA
MLBr_00919|M.leprae_Br4923 EKS-SIHWHMVGQIQRNKVRSLAQWAHTAHSIDSLQLVAALDRAVAAALA
MAV_2342|M.avium_104 TNVAIPRWHMVGHIQRNKARSVARWAHTAHSVDSTHLVSALDRGVAAALA
Mflv_2993|M.gilvum_PYR-GCK REDTPIRWHMVGRIQRNKARSVAEWAYAAHSVDSVKVVAALERSASTALE
Mvan_3518|M.vanbaalenii_PYR-1 --NDPIRWHMVGRIQRNKARSVAQWAYAAHSVDSPKVIAALDRAAEEALD
MSMEG_4220|M.smegmatis_MC2_155 LPDAPIRWHMIGRIQRNKARAVAGWAYAAHSVDNARLIAALDRGAADALG
TH_2376|M.thermoresistible__bu QNASPIRWHMVGRIQRNKARAVARWAYAAHSVDNAKLVAALSRGAVQALD
MAB_2011|M.abscessus_ATCC_1997 AGHADIRWHMVGNLQRNKAKSVAHWAHSVHSVDNARLVTALDG----ARG
:***:*.:****. ::* **::.**:*. ::::**. *
Rv2148c|M.tuberculosis_H37Rv EHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVG
Mb2172c|M.bovis_AF2122/97 EHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVG
MMAR_3188|M.marinum_M DRRRGNPLRVYVQVSLDGDVSRGGVDMTDPGAVDRICAQVSDAQSLELIG
MUL_3496|M.ulcerans_Agy99 DRRRGNPLRVHVQVSLDGDVSRGGVDMTDPGAVDRICAQVSDSQSLELIG
MLBr_00919|M.leprae_Br4923 GGRREQPLQVYVQISLDGDISRGGVNVTAPGAVDRVCAQVEESKSLELVG
MAV_2342|M.avium_104 DGGRIDPMRVYVQVSLDGDESRGGVDISRPGAVDEVCAQVAAANNLDLVG
Mflv_2993|M.gilvum_PYR-GCK EGRRTEPLRVFAQLSLDGDEARGGVDVDATERVDELCAAMDRAGGLTFAG
Mvan_3518|M.vanbaalenii_PYR-1 DGRRPAPLRVYLQVSLDGDEARGGVDVAATDRIDDLCGAVDSARGLEFVG
MSMEG_4220|M.smegmatis_MC2_155 RGVRSEPLRVYLQISLDGDAERGGVDIGDPDLVDELCAAIDGADGLTFTG
TH_2376|M.thermoresistible__bu EGVRTAPVRVYVQVSLDGDERRGGVDVGRPQLVDELCAAVHDAAGLELVG
MAB_2011|M.abscessus_ATCC_1997 AGEKREPLGIYLQVSLDGDNARGGVDIAAADEIDQLCAQVVASEHLELAG
: : :. *:***** ****: . :* :*. : : * : *
Rv2148c|M.tuberculosis_H37Rv LMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHG
Mb2172c|M.bovis_AF2122/97 LMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHG
MMAR_3188|M.marinum_M LMGVPPRDWDQEKAFERLQSEHSRVLESFPTAVRLSAGMSDDLEIAVKHG
MUL_3496|M.ulcerans_Agy99 LMGVPPRDWDQEKAFERLQSEHNRVLESFPTAVRLSAGMSDDLEIAVKHG
MLBr_00919|M.leprae_Br4923 LMGIPPLGWNPDQAFEQLRLEHRRVLRSHPDAIGLSAGMSNDFEIAVKHG
MAV_2342|M.avium_104 LMAIPPLNSDPDEAFDRLQSEHRRVLETHRNAVGLSAGMSDDFEIAVKHG
Mflv_2993|M.gilvum_PYR-GCK MMAIPPLGADPGEAFARLRQERDRVQRDYEQRLGLSAGMSGDLEAAVRHG
Mvan_3518|M.vanbaalenii_PYR-1 LMAIPPLNADAGEAFARLERERDRVQRRFQQRLGLSAGMSGDLEEAVRHG
MSMEG_4220|M.smegmatis_MC2_155 LMAIPPLGADADEAFARLAAERDRVQKAYPQRLEMSAGMSNDLESAVKHG
TH_2376|M.thermoresistible__bu LMGIPPLNWDAEEAFARLAAEHARVQEGYSHRLGLSAGMSGDLEAAVKHG
MAB_2011|M.abscessus_ATCC_1997 LMALPPREADPDQAFRRLQQEHERVRDRYPQANRLSAGMSNDLEAAIKYG
:*.:** : :** :* *: ** . :*****.*:* *:::*
Rv2148c|M.tuberculosis_H37Rv STCVRVGTALLGPRRLRSP------------------------------
Mb2172c|M.bovis_AF2122/97 STCVRVGTALLGPRRLRSP------------------------------
MMAR_3188|M.marinum_M STCVRVGTALLGSRRLRSP------------------------------
MUL_3496|M.ulcerans_Agy99 STCVRVGTALLGSRRLRSP------------------------------
MLBr_00919|M.leprae_Br4923 STCVRVGTALLGPSRLRSP------------------------------
MAV_2342|M.avium_104 STCVRVGTALLGRRPLPSP------------------------------
Mflv_2993|M.gilvum_PYR-GCK STCVRVGTALMGSRPLTSPEVVTRVTPSSQTTPPLDFPESASPQEGSEQ
Mvan_3518|M.vanbaalenii_PYR-1 STCVRVGTALLGSRPLTSPEVVTPVTPSSQTPDSPELPESSPP-EGSSQ
MSMEG_4220|M.smegmatis_MC2_155 STCVRVGTALMGPRPLTSPPVVTPVTSSSQTSELPRSAEGSPD-EHTA-
TH_2376|M.thermoresistible__bu STCVRVGTALLGPRPLTSPAVVTPVTPSSQTPPITRASEGSRD-EHTA-
MAB_2011|M.abscessus_ATCC_1997 STCVRVGTALMGQRPLTSR------------------------------
**********:* * *