For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGA PDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDC HVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPD ALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHT EGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIA AEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTIC PAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAA AATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVW QPQPAAELPMTQRYFLF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1850 | ureC | - | 100% (577) | urease subunit alpha |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1881 | ureC | 0.0 | 100.00% (577) | urease subunit alpha |
| M. gilvum PYR-GCK | Mflv_3352 | ureC | 0.0 | 81.63% (577) | urease subunit alpha |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2425 | ureC | 0.0 | 80.94% (577) | urease subunit alpha |
| M. marinum M | MMAR_2724 | ureC | 0.0 | 88.04% (577) | urease alpha subunit UreC |
| M. avium 104 | MAV_5277 | - | 1e-06 | 29.01% (131) | amidohydrolase family protein, putative |
| M. smegmatis MC2 155 | MSMEG_3625 | ureC | 0.0 | 83.19% (577) | urease subunit alpha |
| M. thermoresistible (build 8) | TH_1059 | ureC | 0.0 | 85.92% (483) | Urease alpha subunit ureC (Urea amidohydrolase) |
| M. ulcerans Agy99 | MUL_3029 | ureC | 0.0 | 87.35% (577) | urease subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_3082 | ureC | 0.0 | 82.32% (577) | urease subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1850|M.tuberculosis_H37Rv MARLSRERYAQLYGPTTG---DRIRLADTNLLVEVTEDRCGGPGLAG---
Mb1881|M.bovis_AF2122/97 MARLSRERYAQLYGPTTG---DRIRLADTNLLVEVTEDRCGGPGLAG---
MMAR_2724|M.marinum_M MARLSRERYAQLYGPTTG---DRIRLADTDLLVEITEDRCGGPGLAG---
MUL_3029|M.ulcerans_Agy99 MARLSRERYAQLYGPTTG---DRIRLADTDLLVEITEDRCGGPGLAG---
Mflv_3352|M.gilvum_PYR-GCK MTRLTRTHYAALFGPTTG---DRIRLADTDLFIEITEDRSGGPGLAG---
Mvan_3082|M.vanbaalenii_PYR-1 MTQLSRERYAALYGPTTG---DRIRLADTDLLIEITEDRSGGPGLAG---
MSMEG_3625|M.smegmatis_MC2_155 MTALSRSNYAALFGPTTG---DRIRLADTDLLIEITEDRSGGPELAG---
MAB_2425|M.abscessus_ATCC_1997 MTRLTREHYAKLYGPTTG---DRIRLADTDLIIEITEDRCGGPGLAG---
TH_1059|M.thermoresistible__bu MTELSRARYGDLYGPTTG---DRIRLADTDLFIEITEDRSGGPGRAG---
MAV_5277|M.avium_104 MFDLKITGGTVVDGTGAQRYRADVGIRDGKIVDVVRADGSEAGGLATAEA
* *. : *. : : : * .:. : * . . *
Rv1850|M.tuberculosis_H37Rv DEAVFGGGKVLRESMGQGRASRADGAP-DTVITGAVIIDYWGIIKADIGI
Mb1881|M.bovis_AF2122/97 DEAVFGGGKVLRESMGQGRASRADGAP-DTVITGAVIIDYWGIIKADIGI
MMAR_2724|M.marinum_M DEAVFGGGKVLRESMGQGRVTRAEGAP-DTVITGAVIIDYWGIIKADIGI
MUL_3029|M.ulcerans_Agy99 DEAVFGGGKVLRESMGQGRVTRAEGAP-DTVITGAVIIDYWGIIKANIGI
Mflv_3352|M.gilvum_PYR-GCK DEAVFGGGKVLRESMGQSRATRADGAP-DTVITGAVILDHWGIIKADIGI
Mvan_3082|M.vanbaalenii_PYR-1 DEAVFGGGKVLRESMGQSRVTRADGAP-DTVITGAVILDYWGIIKADIGI
MSMEG_3625|M.smegmatis_MC2_155 DEAVFGGGKVLRESMGQGRATRADGAP-DTVITGAVILDHWGIIKADIGI
MAB_2425|M.abscessus_ATCC_1997 EEAVFGGGKVLRESMGQSRLTRAGGAP-DTVITGAIIIDHWGIIKADIGI
TH_1059|M.thermoresistible__bu DEAVFGGGKVLRESMGQGRATRADGTP-DTVITGAVIVDHWGIIKADIGI
MAV_5277|M.avium_104 AETIDATGKIVAPGFVDIHTHYDGQVSWDSLLEPSSGHGVTTVVTGNCGV
*:: . **:: .: : : .. *::: : . ::..: *:
Rv1850|M.tuberculosis_H37Rv RDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVH
Mb1881|M.bovis_AF2122/97 RDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVH
MMAR_2724|M.marinum_M RDGRIVAIGKAGNPNIMSGIHPDLVVGPSTEIIGGNGRIVTAGAIDCHVH
MUL_3029|M.ulcerans_Agy99 RDGRIVAIGKAGNPNIMSGIHPDLVVGPSTEIIGGNGRIVTAGAIDCHVH
Mflv_3352|M.gilvum_PYR-GCK RDGRIVGIGKAGNPDIMSGVHPALVVGPSTEIIAGNGRIVTAGAIDCHVH
Mvan_3082|M.vanbaalenii_PYR-1 RDGRITAIGKAGNPDIMTGVHPGLVVGPSTEIIAGNGRIVTAGAIDCHVH
MSMEG_3625|M.smegmatis_MC2_155 RDGRIVAIGKAGNPDIMSGVHPDLVVGPSTEIIAGNGRILTAGAIDCHVH
MAB_2425|M.abscessus_ATCC_1997 RDGRIVGIGKAGNPDIMDGVDPALIVGPSTEIIAGNNRIVTAGGIDCHVH
TH_1059|M.thermoresistible__bu RDGRIVAIGKAGNPDIMTGVHPDLVVGPSTEIIAGNGRILTAGGVDCHVH
MAV_5277|M.avium_104 G----FAPVRPGTEQWLIELMEGVEDIPGTALTEG----ITWGWETYPEY
. :.*. : : : : *.* : * :* * :
Rv1850|M.tuberculosis_H37Rv LICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDG
Mb1881|M.bovis_AF2122/97 LICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDG
MMAR_2724|M.marinum_M LICPQVIAEALGSGITTIIGGGTGPAEGSKSTTVTPGGWHLARMLEALDS
MUL_3029|M.ulcerans_Agy99 LICPQVIAEALSSGITTIIGGGTGPAEGSKSTTVTPGGWHLARMLEALDS
Mflv_3352|M.gilvum_PYR-GCK LICPQIMEEALGGGITTIIAGGTGPAEGSKATTVTPGAWHLARMLEALDT
Mvan_3082|M.vanbaalenii_PYR-1 LICPQIMAEALGGGITTIVAGGTGPAEGSKATTVTPGAWHLARMLEALDT
MSMEG_3625|M.smegmatis_MC2_155 LICPQIMDEALGGGITTIIGGGTGPAEGTKATTVTPGAWHLARMLESLDS
MAB_2425|M.abscessus_ATCC_1997 FICPQILPEALSGGITTMIGGGTGPAEGSKATTVTPGAWHLGRMLQALDG
TH_1059|M.thermoresistible__bu LICPQLAAEALGSGITTLIGGGTGPAEGSKATTVSPGAWHLGRMLEALDC
MAV_5277|M.avium_104 LDAIGKQKFAIDVGSQVAHGAIRAYAMGERGARNEPATPDDIEAMGRLVR
: . *: * . .. . * * :.: *. . . : *
Rv1850|M.tuberculosis_H37Rv WPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVA
Mb1881|M.bovis_AF2122/97 WPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVA
MMAR_2724|M.marinum_M WPVNIALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSSPAAIDACLTVA
MUL_3029|M.ulcerans_Agy99 WPVNIALLGKGNTVNPDALWEQLRGGASGFKLHEDWGKSPAAIDACLTVA
Mflv_3352|M.gilvum_PYR-GCK WPMNVALLGKGNTVSSEAMWEQLRGGAAGFKLHEDWGTTPAAIDACLTVC
Mvan_3082|M.vanbaalenii_PYR-1 WPLNIALLGKGNTVSAEAMWEQLRGGAAGFKLHEDWGTTPAAIDACLTVC
MSMEG_3625|M.smegmatis_MC2_155 WPMNIVLLGKGNTVSADSMWEQLRGGAAGFKLHEDWGTTPAAIDACLTVC
MAB_2425|M.abscessus_ATCC_1997 WPMNILMLGKGNTVNPDAMWEQLRGGAAGFKLHEDWGTTPAVIDACLRVA
TH_1059|M.thermoresistible__bu WPLNIALLGKGNTVNPSALWEQLRGGAAGFKLHEDWGSTPAAIDACLTVA
MAV_5277|M.avium_104 EAIEAGALGFSTSRTMGHRAMDGEPVPGTFAAEEELFGLGRAMAAGGQAV
.:: ** ..: . : . .. * .*: .: : .
Rv1850|M.tuberculosis_H37Rv DVAGVQVALHSDTLN---ETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPD
Mb1881|M.bovis_AF2122/97 DVAGVQVALHSDTLN---ETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPD
MMAR_2724|M.marinum_M DAAGVQVALHSDTLN---EMGFVEDTLAAIAGRSIHTYHTEGAGGGHAPD
MUL_3029|M.ulcerans_Agy99 DAAGVQVALHSDTLN---EMGFVEDTLAAIAGRSIHTYHTEGAGGGHAPD
Mflv_3352|M.gilvum_PYR-GCK EQAGVQANIHTDTLN---EAGFVEDTLAAIKGRSIHAYHTEGAGGGHAPD
Mvan_3082|M.vanbaalenii_PYR-1 DAAGVQANIHTDTLN---EAGFVEHTLAAIKGRSIHAYHTEGAGGGHAPD
MSMEG_3625|M.smegmatis_MC2_155 DAAGVQAAIHTDTLN---EMGFVEDTLAAIGGRSIHAYHTEGAGGGHAPD
MAB_2425|M.abscessus_ATCC_1997 DEADVQVALHSDTLN---ETGFVEGTLAAIGGRAIHAYHTEGAGGGHAPD
TH_1059|M.thermoresistible__bu DAAGVQVALHSDTLN---EAGFVESTLAAIAGRSIHAYHTEGAGGGHAPD
MAV_5277|M.avium_104 FELAPQGAAGEDIIGPKKELDWMRRLSGEIDRPVSFALIQVDADPNLWRE
* * :. * .::. . * .: .*. . :
Rv1850|M.tuberculosis_H37Rv IITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFA
Mb1881|M.bovis_AF2122/97 IITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFA
MMAR_2724|M.marinum_M IITVAAHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFA
MUL_3029|M.ulcerans_Agy99 IITVAAHPNVLPSSTNPTRPHTVNALDEHLDMLMVCHHLNPRIPDDLAFA
Mflv_3352|M.gilvum_PYR-GCK IITVAGHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRVPEDLAFA
Mvan_3082|M.vanbaalenii_PYR-1 IITVAGHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPSVPEDLAFA
MSMEG_3625|M.smegmatis_MC2_155 IITVAGHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLKPSVPEDLAFA
MAB_2425|M.abscessus_ATCC_1997 IITVASHPNVMPSSTNPTRPHTVNTLDEHLDMLMVCHHLNAAVPEDLAFA
TH_1059|M.thermoresistible__bu IITVAAHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLHPGVPEDLAFA
MAV_5277|M.avium_104 MLDLSADAHAAGARLYP-------QIAARPFGMMIGFQGHHGFSHRPTYR
:: ::...:. : * : : :*: .: : ... ::
Rv1850|M.tuberculosis_H37Rv ESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKA
Mb1881|M.bovis_AF2122/97 ESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKA
MMAR_2724|M.marinum_M ESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRVGEVVMRTWQTAHVMKQ
MUL_3029|M.ulcerans_Agy99 ESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRVGEVVMRTWQTAHVMKQ
Mflv_3352|M.gilvum_PYR-GCK ESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKR
Mvan_3082|M.vanbaalenii_PYR-1 ESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKR
MSMEG_3625|M.smegmatis_MC2_155 ESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKR
MAB_2425|M.abscessus_ATCC_1997 ESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRIGEVVMRTWQTAHVMKK
TH_1059|M.thermoresistible__bu ESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKR
MAV_5277|M.avium_104 RLAAECSREELAQRLADPAVKAAILGEDDLPVDPTLLFDGMFALVQHSLH
. . * : * * .. : * .: : :. : .:
Rv1850|M.tuberculosis_H37Rv RRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLA
Mb1881|M.bovis_AF2122/97 RRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLA
MMAR_2724|M.marinum_M RRGALEGDPSGRYSADNNRARRYVAKYTICPAVAHGLDHEVGSVEVGKLA
MUL_3029|M.ulcerans_Agy99 RRGALEGDPSGRYSADNNRARRYVAKYTICPAVAHGLDHEVGSVEVGKLA
Mflv_3352|M.gilvum_PYR-GCK RRGNLAGD----TRADNTRAQRYVAKYTICPAVAHGLDGEIGSVEVGKLA
Mvan_3082|M.vanbaalenii_PYR-1 RRGFLPGD----TKADNARAKRYVAKYTICPAVAHGLDGEIGSVEVGKLA
MSMEG_3625|M.smegmatis_MC2_155 RRGALEGDGSGKNGADNLRARRYVAKYTICPAVAHGLDHEIGSVEVGKLA
MAB_2425|M.abscessus_ATCC_1997 RRGALPGDPSGPNGNDNNRVRRYVAKYTICPAITHGIDHEIGSVEVGKLA
TH_1059|M.thermoresistible__bu RRGALPGDTGGPHGADNHRVRRYVAKYTICPAIAHGLDREVGSVEVGKLA
MAV_5277|M.avium_104 RLYALGDPPDYEPTPDRTVAAIAEARGEDPLATLYDLMLDADATNMLMLP
* * . *. . *: * :.: .:.:: *.
Rv1850|M.tuberculosis_H37Rv DLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTP-QPVLPRPMFGA
Mb1881|M.bovis_AF2122/97 DLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTP-QPVLPRPMFGA
MMAR_2724|M.marinum_M DLVLWEPAFFGVRPHAVVKGGAIAWAAMGDANASIPTP-QPVLPRPMFGA
MUL_3029|M.ulcerans_Agy99 DLVLWEPAFFGVRPHAVVKGGAIAWAAMGDANASIPTP-QPVLPRPMFGA
Mflv_3352|M.gilvum_PYR-GCK DLVLWEPAFFGVRPHAVVKGGMIAWAAMGDANASIPTP-QPVLPRPMFGA
Mvan_3082|M.vanbaalenii_PYR-1 DLVLWEPAFFGVRPHAVVKGGMIAWAAMGDANASIPTP-QPVLPRPMFGA
MSMEG_3625|M.smegmatis_MC2_155 DLVLWEPAFFGVRPHAVIKGGMIAWAAMGDANASIPTP-QPVLPRPMFGA
MAB_2425|M.abscessus_ATCC_1997 DLVLWEPAFFGVRPHAVIKGGGIVWAAMGDANASIPTP-QPVFPRPMFSA
TH_1059|M.thermoresistible__bu DLVLWEPKFFGVRPHAVLKGGMIAWAAMGDANASIPTP-QPVLPXXXPPP
MAV_5277|M.avium_104 LFNYADGNCDAIREMLLHPAGVLGLSDGGAHCGMICDASYPTFLLTHWAR
: : .:* : .* : : * . * . *.:
Rv1850|M.tuberculosis_H37Rv AAATAAATSVHFVAPQSIDARLADRLAVNRGLAP---VADVRAVGKTDLP
Mb1881|M.bovis_AF2122/97 AAATAAATSVHFVAPQSIDARLADRLAVNRGLAP---VADVRAVGKTDLP
MMAR_2724|M.marinum_M SPAVAAATSVHFVAAQSIEAGLADQIAVDRRLVP---VADVRAVGKADMP
MUL_3029|M.ulcerans_Agy99 SPAVAAATSVHFVAAQSIEAGLADQIAVDRRLVP---VADVRAVGKADMP
Mflv_3352|M.gilvum_PYR-GCK APAAAAHTSVHFVAPQAIEDGLADRIAVHRKLVP---VGNVRAVGKAQMP
Mvan_3082|M.vanbaalenii_PYR-1 APAAAAATSVHFVAPQAIEDGLADRIAVNRKLVA---VGNVRGVGKAQMP
MSMEG_3625|M.smegmatis_MC2_155 APAAAAATSVHFVAPQAIEDGLAERIDVRRKLVA---VKDVRKVGKAQMP
MAB_2425|M.abscessus_ATCC_1997 MHAVAAGLAVHFVSPTAIEDDLAARLALRRRLVP---TRDVRNRGKADLP
TH_1059|M.thermoresistible__bu PPDPYGPDRPRFVQSSHPLIGSAP-----DRRVP---CPQVGG-GPACAP
MAV_5277|M.avium_104 DRSRGDKLALEYVIRKQSRDTAHLFGLTDRGTIEPGKKADINVIDMDALR
.:* :: .
Rv1850|M.tuberculosis_H37Rv LNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF---------
Mb1881|M.bovis_AF2122/97 LNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF---------
MMAR_2724|M.marinum_M LNDAQPRIEVDPDTFTVRIDGEVWEQQPATELPMAQRYFLF---------
MUL_3029|M.ulcerans_Agy99 LNDAQPRIEVDPDTFTVRIDGEVWEQQPATELPMAQRYFLF---------
Mflv_3352|M.gilvum_PYR-GCK GNDATPDIRVDPDTFTVRIDGEVWEEQPAEELPMAQRYFLF---------
Mvan_3082|M.vanbaalenii_PYR-1 LNDATPDIEVDPDTFTVRIDGEVWQEQPATELPMAQRYFLF---------
MSMEG_3625|M.smegmatis_MC2_155 LNDALPRIEVEPDTFTVRIDGEVWDEQPAAELPMAQRYFLF---------
MAB_2425|M.abscessus_ATCC_1997 LNDAMPDIRVDPDTFTVRIDGEVWEEHPAAELPMAQRYFLF---------
TH_1059|M.thermoresistible__bu RR----RVSSHPGV------------------------------------
MAV_5277|M.avium_104 LHPAAMAFDLPAGGNRILQGASGYAATIVSGTVTRRNDVDTGARPGRLVR
. . ..
Rv1850|M.tuberculosis_H37Rv ---
Mb1881|M.bovis_AF2122/97 ---
MMAR_2724|M.marinum_M ---
MUL_3029|M.ulcerans_Agy99 ---
Mflv_3352|M.gilvum_PYR-GCK ---
Mvan_3082|M.vanbaalenii_PYR-1 ---
MSMEG_3625|M.smegmatis_MC2_155 ---
MAB_2425|M.abscessus_ATCC_1997 ---
TH_1059|M.thermoresistible__bu ---
MAV_5277|M.avium_104 GAR