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VSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALA ELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDLTG LEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDG EFFGVIAQLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFG GPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYAS YHGAGGLTAIARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSV ACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALADKDIALDRSM IPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQGE YAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCHDNGDVDLDDLRAKVGEHAERL SALMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGG GGPGVGPVAVRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSA NYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEP TESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTAF RPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1832 | gcvB | - | 100% (941) | glycine dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1863 | gcvB | 0.0 | 99.79% (941) | glycine dehydrogenase |
M. gilvum PYR-GCK | Mflv_3398 | - | 0.0 | 83.56% (943) | glycine dehydrogenase |
M. leprae Br4923 | MLBr_02072 | gcvB | 0.0 | 84.98% (939) | glycine dehydrogenase |
M. abscessus ATCC 19977 | MAB_2407 | - | 0.0 | 78.92% (944) | glycine dehydrogenase |
M. marinum M | MMAR_2708 | gcvB | 0.0 | 89.63% (945) | glycine dehydrogenase GcvB |
M. avium 104 | MAV_2884 | gcvP | 0.0 | 88.10% (941) | glycine dehydrogenase |
M. smegmatis MC2 155 | MSMEG_3642 | gcvP | 0.0 | 84.39% (935) | glycine dehydrogenase |
M. thermoresistible (build 8) | TH_0290 | gcvB | 0.0 | 82.37% (556) | Probable glycine dehydrogenase gcvB (Glycine decarboxylase) |
M. ulcerans Agy99 | MUL_3050 | gcvB | 0.0 | 89.10% (945) | glycine dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_3131 | - | 0.0 | 83.33% (942) | glycine dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Rv1832|M.tuberculosis_H37Rv -------------------------------------------------- Mb1863|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2708|M.marinum_M -------------------------------------------------- MUL_3050|M.ulcerans_Agy99 -------------------------------------------------- MAV_2884|M.avium_104 -------------------------------------------------- MLBr_02072|M.leprae_Br4923 -------------------------------------------------- Mflv_3398|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3131|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3642|M.smegmatis_MC2_155 -------------------------------------------------- TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 MTASHDRRRSNTSPSISQAPEPPAAPMPLKSGDPVTEPDRPPTGKGFYQE Rv1832|M.tuberculosis_H37Rv -----------------------------MSDH----STFADRHIGLDSQ Mb1863|M.bovis_AF2122/97 -----------------------------MSDH----STFADRHIGLDSQ MMAR_2708|M.marinum_M -----------------------------MSDHSMFESTFADRHIGLDNQ MUL_3050|M.ulcerans_Agy99 -----------------------------MSDHSMFESTFADRHIGLDNQ MAV_2884|M.avium_104 -----------------------------MPDH----TTFAARHIGPDPQ MLBr_02072|M.leprae_Br4923 ---------------------------MSVPNSSNKQTCFTARHIGPNSE Mflv_3398|M.gilvum_PYR-GCK ---------------------------MPDQTPAPSVLRFVDRHIGPDDQ Mvan_3131|M.vanbaalenii_PYR-1 ---------------------------MSDQFRTPS---FVDRHIGPDAH MSMEG_3642|M.smegmatis_MC2_155 ---------------------------MSDQPKARNP-QFVDRHIGPDES TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 ILRVERPNLSGARDGLMTEGGETLSRAVSRDSASGSAMSFANRHIGPTTA Rv1832|M.tuberculosis_H37Rv AVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAE Mb1863|M.bovis_AF2122/97 AVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAE MMAR_2708|M.marinum_M AIATMLAVIGVDSLDDLAAKAVPTRIFDTPTDSGLAPGLDQLPPAASEAE MUL_3050|M.ulcerans_Agy99 AIATMLAVIGVDSLDDLAAKAVPTRIFDTPTDSGLAPGLDQLPPAASEAE MAV_2884|M.avium_104 AVAAMLDVIGVGSLDELAAKAVPAGIRDRLSADGIAPGLDRLPPPASETE MLBr_02072|M.leprae_Br4923 DVATMLAVIGVESLDDLAAKAVPSDILDNVTDTGVAPGLDRLPPPATESE Mflv_3398|M.gilvum_PYR-GCK AVETLLNTIGVPSLDELAAKALPDVILDRLSTDGVAPGLEHLPAAATEHE Mvan_3131|M.vanbaalenii_PYR-1 AVATLLGTIGVSSLDELAAKALPAGILDPLTGAGTAPGLEHLPPAATEHE MSMEG_3642|M.smegmatis_MC2_155 AVATMLDVIGVSSLDELAAKALPTGILDALDAAGRAPGLAELPPAATEEE TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 DIDTMLATIGVASLDELAEKAVPASILDALR-DGLASGLDALPVAASEHE Rv1832|M.tuberculosis_H37Rv ALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQ Mb1863|M.bovis_AF2122/97 ALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQ MMAR_2708|M.marinum_M ALAELRALADTNTTAVSMIGQGYYDTFTPQVLLRNIMENPAWYTAYTPYQ MUL_3050|M.ulcerans_Agy99 ALAELRALADTNTTAVSMIGQGYYDTFTPQVLLRNIMENPAWYTAYTPYQ MAV_2884|M.avium_104 ALAELRGLAEANTVAVSMIGQGYYDTLTPPVLLRNILENPAWYTAYTPYQ MLBr_02072|M.leprae_Br4923 TLAELGALARANTVAVSMIGQGYYDTLTPAVLSRNILENPAWYTPYTPYQ Mflv_3398|M.gilvum_PYR-GCK ALAELRALAQSNTVAVSMIGQGYYDTLTPPVLRRNIIENPAWYTAYTPYQ Mvan_3131|M.vanbaalenii_PYR-1 ALAELRALAESNTVAVSMIGQGYYDTLTPPVLRRNILENPAWYTAYTPYQ MSMEG_3642|M.smegmatis_MC2_155 ALAELRALADTNTVAVSMIGQGYFDTLTPAVLRRNILENPAWYTAYTPYQ TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 ALDALRKLASQNTVAVSMIGQGYFDTLTPPVLRRHILENPAWYTAYTPYQ Rv1832|M.tuberculosis_H37Rv PEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAAR Mb1863|M.bovis_AF2122/97 PEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAAR MMAR_2708|M.marinum_M PEISQGRLEALLNFQTMVTDLTGLEIANASMLDEGTAAAEAMTLMHRATR MUL_3050|M.ulcerans_Agy99 PEISQGRLEALLNFQTMVTDLTGLEIANASMLDEGTAAAEAMTLMHRATR MAV_2884|M.avium_104 PEISQGRLEALLNFQTMVADLTGLEIANASMLDEGTAAAEAMTLMHRASR MLBr_02072|M.leprae_Br4923 PEISQGRLEALLNFQTLVSDLTGLEIANASMLDEGTAAAEAMTLMYRAAR Mflv_3398|M.gilvum_PYR-GCK PEISQGRLEALLNFQTMVTDLTGLEVANASMLDEGTAAAEAMTLMHRAVR Mvan_3131|M.vanbaalenii_PYR-1 PEISQGRLEALLNFQTMVSDLTGLEVANASMLDEGTAAAEAMTLMHRAVR MSMEG_3642|M.smegmatis_MC2_155 PEISQGRLEALLNFQTMVCDLTGLEVANASMLDEGTAAAEAMTLMHRATR TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 PEISQGRLEALLNFQTMVAELTGLDIANASMLDEGTAAAEAMTLMHRAVK Rv1832|M.tuberculosis_H37Rv GPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIA Mb1863|M.bovis_AF2122/97 GPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGAIA MMAR_2708|M.marinum_M SSTKRLAVDADLFTQTAAVLATRAKPLGIEIVTTDLRDGLPDGEFFGVIA MUL_3050|M.ulcerans_Agy99 SSTKHLAVDADLFTQTAAVLATRAKPLGIEIVTTDLRDGLPDGEFFGVIA MAV_2884|M.avium_104 GKSNRLAVDVDVFAQTAAIVATRARPLGIEIVTADLRDGLPDGDFFGVIA MLBr_02072|M.leprae_Br4923 STASRVVVDVDVFAQTVAVFATRAKPLGIDIVVADLREGLPDGEFFGVIT Mflv_3398|M.gilvum_PYR-GCK GPATRLAVDADVYPQTAAILATRAEPLGIEIVTADLRQGLPDGDFFGVIV Mvan_3131|M.vanbaalenii_PYR-1 GPSNRLVVDSDVYAQTAAVLATRAEPLGIEIVTADLRHGLPDGDFFGVIV MSMEG_3642|M.smegmatis_MC2_155 SKVNRLLVDTDVYAQTAAVLATRARPLGIEIVTADLSKGLPDGEFFGVVV TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 SASNRLVVDADLYPQTAAVIATRAEPLGIDVVTADLAAGLPEGDFFGVIV Rv1832|M.tuberculosis_H37Rv QLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAF Mb1863|M.bovis_AF2122/97 QLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAF MMAR_2708|M.marinum_M QLPGASGRITDWTALIQQAHDRGALVSIGADLLALTLLTPPGEIGADIAF MUL_3050|M.ulcerans_Agy99 QLPGASGRITDWTALIQQAHDRGALVSIGADLLALTLLTPPGEIGADIAF MAV_2884|M.avium_104 QLPGASGAITDWAALVAQAHERGALVALGADLLALTLITPPGEIGADVAF MLBr_02072|M.leprae_Br4923 QLPGASGRITDWTALIAQAHSRGALVAVGADLLALTLITPPGEIGADVAF Mflv_3398|M.gilvum_PYR-GCK QLPGASGVVHDWSALVEQAHERGALVAVGADLLAATMITPPGEIGADVAF Mvan_3131|M.vanbaalenii_PYR-1 QLPGAGGAITDWSELVTQAHDRGALIAVGADLLALTLIAPPGEIGADVAF MSMEG_3642|M.smegmatis_MC2_155 QLPGASGAVVDWAPLIEQAHERKALVAVGADLLALTLITPPGEIGADVAF TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 QLPGASGVVRDWTTLISAAHERGALVAVGADLLALTLVAPPGDIGADVAF Rv1832|M.tuberculosis_H37Rv GTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLA Mb1863|M.bovis_AF2122/97 GTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLA MMAR_2708|M.marinum_M GTTQRFGVPMGFGGPHAGYLSVHAKHARQLPGRLVGVSVDSDGNPAYRLA MUL_3050|M.ulcerans_Agy99 GTTQRFGVPMGFGGPHAGYLSVHAKHARQLPGRLVGVSVDNDGNPAYRLA MAV_2884|M.avium_104 GTTQRFGVPMGFGGPHAGYLAVHANHARQLPGRLVGVSLDADGSPAYRLA MLBr_02072|M.leprae_Br4923 GTTQRFGVPMGFGGPHAGYLALHTKHARQLPGRLVGVSVDSDGTPAYRLA Mflv_3398|M.gilvum_PYR-GCK GTTQRFGVPMGFGGPHAGYLAVHSKHARQLPGRLVGVSVDADGSRAYRLA Mvan_3131|M.vanbaalenii_PYR-1 GTTQRFGVPMGFGGPHAGYLAVHSKHARQLPGRLVGVSVDADGAAAFRLA MSMEG_3642|M.smegmatis_MC2_155 GTTQRFGVPMGFGGPHAGYLAVHANHARQLPGRLVGVSVDSDGSPAYRLA TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 GTTQRFGVPMGFGGPHAGYLAVHTAHARQLPGRLVGVSVDADGSPAYRLS Rv1832|M.tuberculosis_H37Rv LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAH Mb1863|M.bovis_AF2122/97 LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAH MMAR_2708|M.marinum_M LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLTGIARRVHGH MUL_3050|M.ulcerans_Agy99 LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLTGIARRVHGH MAV_2884|M.avium_104 LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGAEGLTAIARRVHGH MLBr_02072|M.leprae_Br4923 LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGAEGLTGIARRVHAQ Mflv_3398|M.gilvum_PYR-GCK LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGPDGLRGIAQRVHGH Mvan_3131|M.vanbaalenii_PYR-1 LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLRAIALRVHAQ MSMEG_3642|M.smegmatis_MC2_155 LQTREQHIRRDKATSNICTAQVLLAVIAAMYASYHGAPGLTAIARRVHAH TH_0290|M.thermoresistible__bu -------------------------------------------------- MAB_2407|M.abscessus_ATCC_1997 LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGPEGLRAIAARIHRN Rv1832|M.tuberculosis_H37Rv AEAIAG---ALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVD Mb1863|M.bovis_AF2122/97 AEAIAG---ALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVD MMAR_2708|M.marinum_M AETIAG---ALGDALVHDTFFDTVLARVPDRADEVVAAAKASGVNLWRVD MUL_3050|M.ulcerans_Agy99 AETIAG---ALGDALVHDTFFDTVLARVPDRADEVVAAAKASGVNLWRVD MAV_2884|M.avium_104 AEAIAA---ALGTAVVHDRYFDTVLARVPGRAHEVIAAAKARGINLWRVD MLBr_02072|M.leprae_Br4923 ARALAAGLSAAGVEVVHQAFFDTVLARVPGRTVQIQGAAKERGINVWLVD Mflv_3398|M.gilvum_PYR-GCK ARALAAGLADAGVEVVHDSFFDTVLAHVPGRADEVRAAAKERGINVWAVD Mvan_3131|M.vanbaalenii_PYR-1 ASALAAGLSGAGIEVVHPSFFDTVLARVPGRASEVRAAAKERGINVWLVD MSMEG_3642|M.smegmatis_MC2_155 ADAIASALGDA---VVHDKFFDTVLVRVPGRADEVVAAAKAKNINLWRVD TH_0290|M.thermoresistible__bu -----------------------VLARVPGRAEQIRAAAKERGINLWLVD MAB_2407|M.abscessus_ATCC_1997 AQLLASGLTRGGHTVVHDRFFDTVLVQVPGRAAQIQAAAKAEGINIWSPD **.:**.*: :: . ** .:*:* * Rv1832|M.tuberculosis_H37Rv ADHVSVACDEATTDTHVAVVLDAFGVAA-AAP----AHTDIATRTSEFLT Mb1863|M.bovis_AF2122/97 ADHVSVACDEATTDTHVAVVLDAFGVAA-AAP----AHADIATRTSEFLT MMAR_2708|M.marinum_M ADHVSVACDEVTTAAHVTAVLDAFGVSA-AKA----ARAEIATRTSEFLT MUL_3050|M.ulcerans_Agy99 ADHVSVACDEVTTAAHVTAVLDAFGVSA-TKA----ARAEIATRTSEFLT MAV_2884|M.avium_104 DDHVSVACDEATTDEHVAAVLEAFGVAP-AEP----VASEIATRTSEFLT MLBr_02072|M.leprae_Br4923 GDHVSVACDEATTDEHITAVLAAFAATP-ARAS--FAGPDIATRTSAFLT Mflv_3398|M.gilvum_PYR-GCK ADHVSVACDEATTAEHVADVLAAFGAAP-SGAD--FAGPAVATRTSEFLT Mvan_3131|M.vanbaalenii_PYR-1 DDHISVSCDEATTDGHVADVLAAFSAEPTVGGD--VTAASIVTRISEFLT MSMEG_3642|M.smegmatis_MC2_155 DDHVSVSCDEATTDAHIDAVIKAFGATR---TD--GAGTDIATRTSEFLT TH_0290|M.thermoresistible__bu ADHVSVSCDEATRPEHVTEVLAAFGATP-VDEP--FTGPDIATRTTPFLT MAB_2407|M.abscessus_ATCC_1997 GDHVSIACDEATTVPHLVAVLRAFGSEIGQDTAGAPGASDIATRGSDYLT **:*::***.* *: *: **. . :.** : :** Rv1832|M.tuberculosis_H37Rv HPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI Mb1863|M.bovis_AF2122/97 HPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI MMAR_2708|M.marinum_M HPAFTNYRTETSMMRYLRELADKDIALDRSMIPLGSCTMKLNAATEMESI MUL_3050|M.ulcerans_Agy99 HPAFTNYRTETSMMRYLRELADKDIALDRSMIPLGSCTMKLNAATEMESI MAV_2884|M.avium_104 HPAFTQYRTETAMMRYLRTLADKDIALDRSMIPLGSCTMKLNAAAEMEPI MLBr_02072|M.leprae_Br4923 HPTFTKYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI Mflv_3398|M.gilvum_PYR-GCK HPAFSDYRTETSMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEAI Mvan_3131|M.vanbaalenii_PYR-1 HPAFTRYRTETEMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMEPI MSMEG_3642|M.smegmatis_MC2_155 HPAFHRYRTETEMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEPI TH_0290|M.thermoresistible__bu HPAFTRYRTETEMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEPI MAB_2407|M.abscessus_ATCC_1997 HPAFNRYHSETEMMRYLRALSDKDIALDRSMIPLGSCTMKLNAAAEMEPI **:* *::** ****** *:***********************:***.* Rv1832|M.tuberculosis_H37Rv TWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQG Mb1863|M.bovis_AF2122/97 TWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQG MMAR_2708|M.marinum_M TWPELGRQHPFAPASDTPGLRRLITELQGWLAAITGYDEVSLQPNAGSQG MUL_3050|M.ulcerans_Agy99 TWPELGRQHPFAPASDTPGLRRLITELQGWLAAITGYDEVSLQPNAGSQG MAV_2884|M.avium_104 TWPEFARQHPFAPASDTPGLRRLIGDLENWLVAITGYDAVSLQPNAGSQG MLBr_02072|M.leprae_Br4923 TWQEFTRQHPFAPVSDTPGLRRLISDLESWLVQITGYDAVSLQPNAGSQG Mflv_3398|M.gilvum_PYR-GCK TWAEFGRQHPFAPASDTPGLRRLIADLQSWLTGITGYDEISLQPNAGSQG Mvan_3131|M.vanbaalenii_PYR-1 TWPEFARQHPFAPASDTPGIRRLIADLQGWLTGITGYDEISLQPNAGSQG MSMEG_3642|M.smegmatis_MC2_155 TWTEFSRQHPFAPASDTPGLRKLIADLQSWLTAITGYDEVSLQPNAGSQG TH_0290|M.thermoresistible__bu TWPEFTRLHPFAPKEDTPGIRRLIADLEQWLAHITGYAAVSLQPNAGSQG MAB_2407|M.abscessus_ATCC_1997 TWPQFAALHPFAPAGDSRGLRTLIADLEGWLADITGYDKVSLQPNAGSQG ** :: ***** *: *:* *: :*: **. **** :********** Rv1832|M.tuberculosis_H37Rv EYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCH Mb1863|M.bovis_AF2122/97 EYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCH MMAR_2708|M.marinum_M EYSGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH MUL_3050|M.ulcerans_Agy99 EYSGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH MAV_2884|M.avium_104 EYAGLLAIHDYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH MLBr_02072|M.leprae_Br4923 EYAGLLAIHDYHVSRGEPHRNVCLIPSSAHGTNAASAALVGMRVVVVGCH Mflv_3398|M.gilvum_PYR-GCK EYAGLLAIQAYHHARGDSGRTVCLIPSSAHGTNAASAAMVGMKVVVVACR Mvan_3131|M.vanbaalenii_PYR-1 EYAGLLAIRAYHAARGDTDRTVCLIPASAHGTNAASAAMVGMQVVVVACR MSMEG_3642|M.smegmatis_MC2_155 EYAGLLAIKAYHEARGDADRDICLIPSSAHGTNAASAALAGMRVVVVACR TH_0290|M.thermoresistible__bu EYAGLLAIQAYHAERGEPQRDVCLIPSSAHGTNAASAALAGMRVVVVGCR MAB_2407|M.abscessus_ATCC_1997 EYAGLLAIRQYHIDRGDSGRDVCLIPSSAHGTNAASAALAGMRVVVVACR **:*****: ** **:. * :****:***********:.**:**** *: Rv1832|M.tuberculosis_H37Rv DNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAG Mb1863|M.bovis_AF2122/97 DNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAG MMAR_2708|M.marinum_M DNGDVDLDDLRAKVGEHADRLAALMITYPSTHGVYEHDIADICAAVHDAG MUL_3050|M.ulcerans_Agy99 DNGDVDLDDLRAKVGEHADRLAALMITYPSTHGVYEHDIADICAAVHDAG MAV_2884|M.avium_104 DNGDVDLDDLRAKVTDHRDRLSTLMITYPSTHGVYEHDIAEICAAVHDAG MLBr_02072|M.leprae_Br4923 DNGDVDLDDLRIKLSEHANRLSVLMITYPSTHGVYEHDIAEICAAVHDAG Mflv_3398|M.gilvum_PYR-GCK ANGDVDLDDLRAKVTEHADRLSALMITYPSTHGVYEHDIADICAAVHDAG Mvan_3131|M.vanbaalenii_PYR-1 ANGDVDLDDLRAKVTEHAERLAALMITYPSTHGVYEHDIAEICAAVHDAG MSMEG_3642|M.smegmatis_MC2_155 ENGDVDLDDLRTKVKEHADRIAALMITYPSTHGVYEHDVADICAAVHDVG TH_0290|M.thermoresistible__bu PNGDVDLDDLRVKIAEHSDRLAALMITYPSTHGVYEHDVAEICAAVHDAG MAB_2407|M.abscessus_ATCC_1997 ENGDVDLDDLRAKIAANASALSAIMITYPSTHGVYEHDIADICAAVHDAG ********** *: : . ::.:**************:*:*******.* Rv1832|M.tuberculosis_H37Rv GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA Mb1863|M.bovis_AF2122/97 GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MMAR_2708|M.marinum_M GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MUL_3050|M.ulcerans_Agy99 GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MAV_2884|M.avium_104 GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MLBr_02072|M.leprae_Br4923 GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA Mflv_3398|M.gilvum_PYR-GCK GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA Mvan_3131|M.vanbaalenii_PYR-1 GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MSMEG_3642|M.smegmatis_MC2_155 GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA TH_0290|M.thermoresistible__bu GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA MAB_2407|M.abscessus_ATCC_1997 GQVYVDGANLNALVGLARPGHFGGDVSHLNLHKTFCIPHGGGGPGVGPVA ********************:***************************** Rv1832|M.tuberculosis_H37Rv VRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGL Mb1863|M.bovis_AF2122/97 VRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGL MMAR_2708|M.marinum_M VRSHLAPFLPGHPFAPELPQGDPVSAAPYGSASILPITWAYIRMMGADGL MUL_3050|M.ulcerans_Agy99 VRSHLAPFLPGHPFAPGLPQGDPVSAAPYGSASILPITWAYIRMMGADGL MAV_2884|M.avium_104 VRSHLAPFLPGHPHAPELPQGHPVSSAPYGSASILPISWAYIRMMGADGL MLBr_02072|M.leprae_Br4923 VRSHLVSFLPGHPFAPELPQGQPVSSAPYGSASLLPITWAYIRMMGADGL Mflv_3398|M.gilvum_PYR-GCK VRAHLAPYLPGHPLAAELSDDHTVSAAPYGSASILPITWAYIRMMGAAGL Mvan_3131|M.vanbaalenii_PYR-1 VRSHLAPYLPGHPLADELSDEHTVSAAPYGSASILPITWAYIRMMGAQGL MSMEG_3642|M.smegmatis_MC2_155 VRAHLAPYLPGHPLADELSDDHTVSAAPYGSASILPITWMYIRMMGADGL TH_0290|M.thermoresistible__bu VGVHLAKYLPGHPLADELGDTLTVSAAPYGSASILPITWMYIRMMGAQGL MAB_2407|M.abscessus_ATCC_1997 VRSHLAQYLPGHPYAEELPAGAPVSSAPYGSASILPITWAYIRMMGPDGL * **. :***** * * .**:*******:***:* ******. ** Rv1832|M.tuberculosis_H37Rv RAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGI Mb1863|M.bovis_AF2122/97 RAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGI MMAR_2708|M.marinum_M RAASLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRGITKATGV MUL_3050|M.ulcerans_Agy99 RAASLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRGIPKATGV MAV_2884|M.avium_104 RAASLTAITSANYIARRLDEYFPVLYTGENGMVAHECILDLRPITKATGV MLBr_02072|M.leprae_Br4923 RTASLTAIASANYIARRLDKYFPVLYTGENGMVAHECILDLRPITKSVGV Mflv_3398|M.gilvum_PYR-GCK RSATLVAIASANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKATGV Mvan_3131|M.vanbaalenii_PYR-1 RSASLVAIASANYIARRLDEYYPVLYTGENGMVAHECILDLRAITKATGV MSMEG_3642|M.smegmatis_MC2_155 RAATLTAIASANYVARRLDEYFPVLYTGENGMVAHECILDLRGITKATGV TH_0290|M.thermoresistible__bu RTATLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRPLTKATGV MAB_2407|M.abscessus_ATCC_1997 RAASLTAIASANYLARRLDEYYPVLYTGDNGMVAHECILDLREITKNTGV *:*:*.**:****:*****:*:******:************* :.* .*: Rv1832|M.tuberculosis_H37Rv TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGI Mb1863|M.bovis_AF2122/97 TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGI MMAR_2708|M.marinum_M TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCDAMISI MUL_3050|M.ulcerans_Agy99 TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCDAMISI MAV_2884|M.avium_104 TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESETLTEVDAFCDAMIAI MLBr_02072|M.leprae_Br4923 TVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESLAEIDAFCEAMIAI Mflv_3398|M.gilvum_PYR-GCK TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLSEIDAFCDAMIAI Mvan_3131|M.vanbaalenii_PYR-1 TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIAI MSMEG_3642|M.smegmatis_MC2_155 TVDDVAKRLADFGFHAPTMSFPVSGTLMVEPTESESLAEVDAFCDAMIAI TH_0290|M.thermoresistible__bu TVDDVAKRLADFGFHAPTMSFPVAGTLMVEPTESESLAEIDAFCEAMIAI MAB_2407|M.abscessus_ATCC_1997 TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIAI ***********:***********.***********:*:*:****:***.* Rv1832|M.tuberculosis_H37Rv RAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTA Mb1863|M.bovis_AF2122/97 RAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTA MMAR_2708|M.marinum_M RAEIDRVGSGQWPVDDNPLRGAPHTAQCLLVGEWDHPYTREEAAYPLGTA MUL_3050|M.ulcerans_Agy99 RAEIDRVGSGQWPVDDNPLRGAPHTAQCLLVGEWDHPYTREEAAYPLGTA MAV_2884|M.avium_104 RGEIDRVGAGEWPVEDNPLRGAPHTAECLVTTDWDHPYSREQAAYPLGKD MLBr_02072|M.leprae_Br4923 RGEIARVGAGEWSVEDNPLRGAPHTAECLLASDWDHPYTREEAAYPLGKA Mflv_3398|M.gilvum_PYR-GCK RAEIDRVGSGEWPVDDNPLRGAPHTAESLLVEEWTHPYTREQAAYPLGKG Mvan_3131|M.vanbaalenii_PYR-1 RGEIDKVGSGMWSVDDNPLRGAPHTAESLLVEDWHHPYTREQAAYPLGKG MSMEG_3642|M.smegmatis_MC2_155 RGEIDRVGSGEWPVDDNPLRGAPHTADCLLVADWNRPYTREEAAYPLGKG TH_0290|M.thermoresistible__bu RREIDRVGSGEWPVDDNPLRNAPHTAECLIAGEWNHPYTREQAAYPLGTG MAB_2407|M.abscessus_ATCC_1997 KSEIDKVGSGVWPAQDNPLRGAPHTAESLIADEWHHPYTRAEAAYPLGRG : ** :**:* *..:*****.*****:.*:. :* :**:* :****** Rv1832|M.tuberculosis_H37Rv FRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA- Mb1863|M.bovis_AF2122/97 FRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA- MMAR_2708|M.marinum_M FRPKVWPAARRIDGAYGDRNLVCSCPPVEAFA- MUL_3050|M.ulcerans_Agy99 FRPKVWPAARRIDGAYGDRNLVCSCPPVEAFA- MAV_2884|M.avium_104 FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA- MLBr_02072|M.leprae_Br4923 FRPKVWPPVRRIDGVYGDRNLVCSCLPVEAFV- Mflv_3398|M.gilvum_PYR-GCK FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA- Mvan_3131|M.vanbaalenii_PYR-1 FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA- MSMEG_3642|M.smegmatis_MC2_155 WRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA- TH_0290|M.thermoresistible__bu FRPKVWPPVRRIDGAYGDRNLVCSCPPIEAYA- MAB_2407|M.abscessus_ATCC_1997 FRPKVWPPVRRIDGAYGDRNLVCSCPPIEAFAQ :******..*****.********** *:**:.