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M. tuberculosis H37Rv Rv1832 (gcvB)

annotation: glycine dehydrogenase
coordinates: 2075877 - 2078702
length: 941

VSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALA
ELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDLTG
LEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDG
EFFGVIAQLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFG
GPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYAS
YHGAGGLTAIARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSV
ACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALADKDIALDRSM
IPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQGE
YAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCHDNGDVDLDDLRAKVGEHAERL
SALMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGG
GGPGVGPVAVRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSA
NYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEP
TESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTAF
RPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1832gcvB-100% (941)glycine dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1863gcvB0.099.79% (941) glycine dehydrogenase
M. gilvum PYR-GCKMflv_3398-0.083.56% (943) glycine dehydrogenase
M. leprae Br4923MLBr_02072gcvB0.084.98% (939) glycine dehydrogenase
M. abscessus ATCC 19977MAB_2407-0.078.92% (944) glycine dehydrogenase
M. marinum MMMAR_2708gcvB0.089.63% (945) glycine dehydrogenase GcvB
M. avium 104MAV_2884gcvP0.088.10% (941) glycine dehydrogenase
M. smegmatis MC2 155MSMEG_3642gcvP0.084.39% (935) glycine dehydrogenase
M. thermoresistible (build 8)TH_0290gcvB0.082.37% (556) Probable glycine dehydrogenase gcvB (Glycine decarboxylase)
M. ulcerans Agy99MUL_3050gcvB0.089.10% (945) glycine dehydrogenase
M. vanbaalenii PYR-1Mvan_3131-0.083.33% (942) glycine dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1832|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1863|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2708|M.marinum_M               --------------------------------------------------
MUL_3050|M.ulcerans_Agy99           --------------------------------------------------
MAV_2884|M.avium_104                --------------------------------------------------
MLBr_02072|M.leprae_Br4923          --------------------------------------------------
Mflv_3398|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3131|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3642|M.smegmatis_MC2_155      --------------------------------------------------
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      MTASHDRRRSNTSPSISQAPEPPAAPMPLKSGDPVTEPDRPPTGKGFYQE
                                                                                      

Rv1832|M.tuberculosis_H37Rv         -----------------------------MSDH----STFADRHIGLDSQ
Mb1863|M.bovis_AF2122/97            -----------------------------MSDH----STFADRHIGLDSQ
MMAR_2708|M.marinum_M               -----------------------------MSDHSMFESTFADRHIGLDNQ
MUL_3050|M.ulcerans_Agy99           -----------------------------MSDHSMFESTFADRHIGLDNQ
MAV_2884|M.avium_104                -----------------------------MPDH----TTFAARHIGPDPQ
MLBr_02072|M.leprae_Br4923          ---------------------------MSVPNSSNKQTCFTARHIGPNSE
Mflv_3398|M.gilvum_PYR-GCK          ---------------------------MPDQTPAPSVLRFVDRHIGPDDQ
Mvan_3131|M.vanbaalenii_PYR-1       ---------------------------MSDQFRTPS---FVDRHIGPDAH
MSMEG_3642|M.smegmatis_MC2_155      ---------------------------MSDQPKARNP-QFVDRHIGPDES
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      ILRVERPNLSGARDGLMTEGGETLSRAVSRDSASGSAMSFANRHIGPTTA
                                                                                      

Rv1832|M.tuberculosis_H37Rv         AVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAE
Mb1863|M.bovis_AF2122/97            AVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAE
MMAR_2708|M.marinum_M               AIATMLAVIGVDSLDDLAAKAVPTRIFDTPTDSGLAPGLDQLPPAASEAE
MUL_3050|M.ulcerans_Agy99           AIATMLAVIGVDSLDDLAAKAVPTRIFDTPTDSGLAPGLDQLPPAASEAE
MAV_2884|M.avium_104                AVAAMLDVIGVGSLDELAAKAVPAGIRDRLSADGIAPGLDRLPPPASETE
MLBr_02072|M.leprae_Br4923          DVATMLAVIGVESLDDLAAKAVPSDILDNVTDTGVAPGLDRLPPPATESE
Mflv_3398|M.gilvum_PYR-GCK          AVETLLNTIGVPSLDELAAKALPDVILDRLSTDGVAPGLEHLPAAATEHE
Mvan_3131|M.vanbaalenii_PYR-1       AVATLLGTIGVSSLDELAAKALPAGILDPLTGAGTAPGLEHLPPAATEHE
MSMEG_3642|M.smegmatis_MC2_155      AVATMLDVIGVSSLDELAAKALPTGILDALDAAGRAPGLAELPPAATEEE
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      DIDTMLATIGVASLDELAEKAVPASILDALR-DGLASGLDALPVAASEHE
                                                                                      

Rv1832|M.tuberculosis_H37Rv         ALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQ
Mb1863|M.bovis_AF2122/97            ALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQ
MMAR_2708|M.marinum_M               ALAELRALADTNTTAVSMIGQGYYDTFTPQVLLRNIMENPAWYTAYTPYQ
MUL_3050|M.ulcerans_Agy99           ALAELRALADTNTTAVSMIGQGYYDTFTPQVLLRNIMENPAWYTAYTPYQ
MAV_2884|M.avium_104                ALAELRGLAEANTVAVSMIGQGYYDTLTPPVLLRNILENPAWYTAYTPYQ
MLBr_02072|M.leprae_Br4923          TLAELGALARANTVAVSMIGQGYYDTLTPAVLSRNILENPAWYTPYTPYQ
Mflv_3398|M.gilvum_PYR-GCK          ALAELRALAQSNTVAVSMIGQGYYDTLTPPVLRRNIIENPAWYTAYTPYQ
Mvan_3131|M.vanbaalenii_PYR-1       ALAELRALAESNTVAVSMIGQGYYDTLTPPVLRRNILENPAWYTAYTPYQ
MSMEG_3642|M.smegmatis_MC2_155      ALAELRALADTNTVAVSMIGQGYFDTLTPAVLRRNILENPAWYTAYTPYQ
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      ALDALRKLASQNTVAVSMIGQGYFDTLTPPVLRRHILENPAWYTAYTPYQ
                                                                                      

Rv1832|M.tuberculosis_H37Rv         PEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAAR
Mb1863|M.bovis_AF2122/97            PEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAAR
MMAR_2708|M.marinum_M               PEISQGRLEALLNFQTMVTDLTGLEIANASMLDEGTAAAEAMTLMHRATR
MUL_3050|M.ulcerans_Agy99           PEISQGRLEALLNFQTMVTDLTGLEIANASMLDEGTAAAEAMTLMHRATR
MAV_2884|M.avium_104                PEISQGRLEALLNFQTMVADLTGLEIANASMLDEGTAAAEAMTLMHRASR
MLBr_02072|M.leprae_Br4923          PEISQGRLEALLNFQTLVSDLTGLEIANASMLDEGTAAAEAMTLMYRAAR
Mflv_3398|M.gilvum_PYR-GCK          PEISQGRLEALLNFQTMVTDLTGLEVANASMLDEGTAAAEAMTLMHRAVR
Mvan_3131|M.vanbaalenii_PYR-1       PEISQGRLEALLNFQTMVSDLTGLEVANASMLDEGTAAAEAMTLMHRAVR
MSMEG_3642|M.smegmatis_MC2_155      PEISQGRLEALLNFQTMVCDLTGLEVANASMLDEGTAAAEAMTLMHRATR
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      PEISQGRLEALLNFQTMVAELTGLDIANASMLDEGTAAAEAMTLMHRAVK
                                                                                      

Rv1832|M.tuberculosis_H37Rv         GPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIA
Mb1863|M.bovis_AF2122/97            GPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGAIA
MMAR_2708|M.marinum_M               SSTKRLAVDADLFTQTAAVLATRAKPLGIEIVTTDLRDGLPDGEFFGVIA
MUL_3050|M.ulcerans_Agy99           SSTKHLAVDADLFTQTAAVLATRAKPLGIEIVTTDLRDGLPDGEFFGVIA
MAV_2884|M.avium_104                GKSNRLAVDVDVFAQTAAIVATRARPLGIEIVTADLRDGLPDGDFFGVIA
MLBr_02072|M.leprae_Br4923          STASRVVVDVDVFAQTVAVFATRAKPLGIDIVVADLREGLPDGEFFGVIT
Mflv_3398|M.gilvum_PYR-GCK          GPATRLAVDADVYPQTAAILATRAEPLGIEIVTADLRQGLPDGDFFGVIV
Mvan_3131|M.vanbaalenii_PYR-1       GPSNRLVVDSDVYAQTAAVLATRAEPLGIEIVTADLRHGLPDGDFFGVIV
MSMEG_3642|M.smegmatis_MC2_155      SKVNRLLVDTDVYAQTAAVLATRARPLGIEIVTADLSKGLPDGEFFGVVV
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      SASNRLVVDADLYPQTAAVIATRAEPLGIDVVTADLAAGLPEGDFFGVIV
                                                                                      

Rv1832|M.tuberculosis_H37Rv         QLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAF
Mb1863|M.bovis_AF2122/97            QLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAF
MMAR_2708|M.marinum_M               QLPGASGRITDWTALIQQAHDRGALVSIGADLLALTLLTPPGEIGADIAF
MUL_3050|M.ulcerans_Agy99           QLPGASGRITDWTALIQQAHDRGALVSIGADLLALTLLTPPGEIGADIAF
MAV_2884|M.avium_104                QLPGASGAITDWAALVAQAHERGALVALGADLLALTLITPPGEIGADVAF
MLBr_02072|M.leprae_Br4923          QLPGASGRITDWTALIAQAHSRGALVAVGADLLALTLITPPGEIGADVAF
Mflv_3398|M.gilvum_PYR-GCK          QLPGASGVVHDWSALVEQAHERGALVAVGADLLAATMITPPGEIGADVAF
Mvan_3131|M.vanbaalenii_PYR-1       QLPGAGGAITDWSELVTQAHDRGALIAVGADLLALTLIAPPGEIGADVAF
MSMEG_3642|M.smegmatis_MC2_155      QLPGASGAVVDWAPLIEQAHERKALVAVGADLLALTLITPPGEIGADVAF
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      QLPGASGVVRDWTTLISAAHERGALVAVGADLLALTLVAPPGDIGADVAF
                                                                                      

Rv1832|M.tuberculosis_H37Rv         GTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLA
Mb1863|M.bovis_AF2122/97            GTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLA
MMAR_2708|M.marinum_M               GTTQRFGVPMGFGGPHAGYLSVHAKHARQLPGRLVGVSVDSDGNPAYRLA
MUL_3050|M.ulcerans_Agy99           GTTQRFGVPMGFGGPHAGYLSVHAKHARQLPGRLVGVSVDNDGNPAYRLA
MAV_2884|M.avium_104                GTTQRFGVPMGFGGPHAGYLAVHANHARQLPGRLVGVSLDADGSPAYRLA
MLBr_02072|M.leprae_Br4923          GTTQRFGVPMGFGGPHAGYLALHTKHARQLPGRLVGVSVDSDGTPAYRLA
Mflv_3398|M.gilvum_PYR-GCK          GTTQRFGVPMGFGGPHAGYLAVHSKHARQLPGRLVGVSVDADGSRAYRLA
Mvan_3131|M.vanbaalenii_PYR-1       GTTQRFGVPMGFGGPHAGYLAVHSKHARQLPGRLVGVSVDADGAAAFRLA
MSMEG_3642|M.smegmatis_MC2_155      GTTQRFGVPMGFGGPHAGYLAVHANHARQLPGRLVGVSVDSDGSPAYRLA
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      GTTQRFGVPMGFGGPHAGYLAVHTAHARQLPGRLVGVSVDADGSPAYRLS
                                                                                      

Rv1832|M.tuberculosis_H37Rv         LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAH
Mb1863|M.bovis_AF2122/97            LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAH
MMAR_2708|M.marinum_M               LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLTGIARRVHGH
MUL_3050|M.ulcerans_Agy99           LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLTGIARRVHGH
MAV_2884|M.avium_104                LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGAEGLTAIARRVHGH
MLBr_02072|M.leprae_Br4923          LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGAEGLTGIARRVHAQ
Mflv_3398|M.gilvum_PYR-GCK          LQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGPDGLRGIAQRVHGH
Mvan_3131|M.vanbaalenii_PYR-1       LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGADGLRAIALRVHAQ
MSMEG_3642|M.smegmatis_MC2_155      LQTREQHIRRDKATSNICTAQVLLAVIAAMYASYHGAPGLTAIARRVHAH
TH_0290|M.thermoresistible__bu      --------------------------------------------------
MAB_2407|M.abscessus_ATCC_1997      LQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGPEGLRAIAARIHRN
                                                                                      

Rv1832|M.tuberculosis_H37Rv         AEAIAG---ALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVD
Mb1863|M.bovis_AF2122/97            AEAIAG---ALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVD
MMAR_2708|M.marinum_M               AETIAG---ALGDALVHDTFFDTVLARVPDRADEVVAAAKASGVNLWRVD
MUL_3050|M.ulcerans_Agy99           AETIAG---ALGDALVHDTFFDTVLARVPDRADEVVAAAKASGVNLWRVD
MAV_2884|M.avium_104                AEAIAA---ALGTAVVHDRYFDTVLARVPGRAHEVIAAAKARGINLWRVD
MLBr_02072|M.leprae_Br4923          ARALAAGLSAAGVEVVHQAFFDTVLARVPGRTVQIQGAAKERGINVWLVD
Mflv_3398|M.gilvum_PYR-GCK          ARALAAGLADAGVEVVHDSFFDTVLAHVPGRADEVRAAAKERGINVWAVD
Mvan_3131|M.vanbaalenii_PYR-1       ASALAAGLSGAGIEVVHPSFFDTVLARVPGRASEVRAAAKERGINVWLVD
MSMEG_3642|M.smegmatis_MC2_155      ADAIASALGDA---VVHDKFFDTVLVRVPGRADEVVAAAKAKNINLWRVD
TH_0290|M.thermoresistible__bu      -----------------------VLARVPGRAEQIRAAAKERGINLWLVD
MAB_2407|M.abscessus_ATCC_1997      AQLLASGLTRGGHTVVHDRFFDTVLVQVPGRAAQIQAAAKAEGINIWSPD
                                                           **.:**.*: :: . **  .:*:*  *

Rv1832|M.tuberculosis_H37Rv         ADHVSVACDEATTDTHVAVVLDAFGVAA-AAP----AHTDIATRTSEFLT
Mb1863|M.bovis_AF2122/97            ADHVSVACDEATTDTHVAVVLDAFGVAA-AAP----AHADIATRTSEFLT
MMAR_2708|M.marinum_M               ADHVSVACDEVTTAAHVTAVLDAFGVSA-AKA----ARAEIATRTSEFLT
MUL_3050|M.ulcerans_Agy99           ADHVSVACDEVTTAAHVTAVLDAFGVSA-TKA----ARAEIATRTSEFLT
MAV_2884|M.avium_104                DDHVSVACDEATTDEHVAAVLEAFGVAP-AEP----VASEIATRTSEFLT
MLBr_02072|M.leprae_Br4923          GDHVSVACDEATTDEHITAVLAAFAATP-ARAS--FAGPDIATRTSAFLT
Mflv_3398|M.gilvum_PYR-GCK          ADHVSVACDEATTAEHVADVLAAFGAAP-SGAD--FAGPAVATRTSEFLT
Mvan_3131|M.vanbaalenii_PYR-1       DDHISVSCDEATTDGHVADVLAAFSAEPTVGGD--VTAASIVTRISEFLT
MSMEG_3642|M.smegmatis_MC2_155      DDHVSVSCDEATTDAHIDAVIKAFGATR---TD--GAGTDIATRTSEFLT
TH_0290|M.thermoresistible__bu      ADHVSVSCDEATRPEHVTEVLAAFGATP-VDEP--FTGPDIATRTTPFLT
MAB_2407|M.abscessus_ATCC_1997      GDHVSIACDEATTVPHLVAVLRAFGSEIGQDTAGAPGASDIATRGSDYLT
                                     **:*::***.*   *:  *: **.             . :.** : :**

Rv1832|M.tuberculosis_H37Rv         HPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI
Mb1863|M.bovis_AF2122/97            HPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI
MMAR_2708|M.marinum_M               HPAFTNYRTETSMMRYLRELADKDIALDRSMIPLGSCTMKLNAATEMESI
MUL_3050|M.ulcerans_Agy99           HPAFTNYRTETSMMRYLRELADKDIALDRSMIPLGSCTMKLNAATEMESI
MAV_2884|M.avium_104                HPAFTQYRTETAMMRYLRTLADKDIALDRSMIPLGSCTMKLNAAAEMEPI
MLBr_02072|M.leprae_Br4923          HPTFTKYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESI
Mflv_3398|M.gilvum_PYR-GCK          HPAFSDYRTETSMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEAI
Mvan_3131|M.vanbaalenii_PYR-1       HPAFTRYRTETEMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMEPI
MSMEG_3642|M.smegmatis_MC2_155      HPAFHRYRTETEMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEPI
TH_0290|M.thermoresistible__bu      HPAFTRYRTETEMMRYLRSLADKDIALDRSMIPLGSCTMKLNAAAEMEPI
MAB_2407|M.abscessus_ATCC_1997      HPAFNRYHSETEMMRYLRALSDKDIALDRSMIPLGSCTMKLNAAAEMEPI
                                    **:*  *::** ****** *:***********************:***.*

Rv1832|M.tuberculosis_H37Rv         TWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQG
Mb1863|M.bovis_AF2122/97            TWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQG
MMAR_2708|M.marinum_M               TWPELGRQHPFAPASDTPGLRRLITELQGWLAAITGYDEVSLQPNAGSQG
MUL_3050|M.ulcerans_Agy99           TWPELGRQHPFAPASDTPGLRRLITELQGWLAAITGYDEVSLQPNAGSQG
MAV_2884|M.avium_104                TWPEFARQHPFAPASDTPGLRRLIGDLENWLVAITGYDAVSLQPNAGSQG
MLBr_02072|M.leprae_Br4923          TWQEFTRQHPFAPVSDTPGLRRLISDLESWLVQITGYDAVSLQPNAGSQG
Mflv_3398|M.gilvum_PYR-GCK          TWAEFGRQHPFAPASDTPGLRRLIADLQSWLTGITGYDEISLQPNAGSQG
Mvan_3131|M.vanbaalenii_PYR-1       TWPEFARQHPFAPASDTPGIRRLIADLQGWLTGITGYDEISLQPNAGSQG
MSMEG_3642|M.smegmatis_MC2_155      TWTEFSRQHPFAPASDTPGLRKLIADLQSWLTAITGYDEVSLQPNAGSQG
TH_0290|M.thermoresistible__bu      TWPEFTRLHPFAPKEDTPGIRRLIADLEQWLAHITGYAAVSLQPNAGSQG
MAB_2407|M.abscessus_ATCC_1997      TWPQFAALHPFAPAGDSRGLRTLIADLEGWLADITGYDKVSLQPNAGSQG
                                    ** ::   *****  *: *:* *: :*: **. ****  :**********

Rv1832|M.tuberculosis_H37Rv         EYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCH
Mb1863|M.bovis_AF2122/97            EYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCH
MMAR_2708|M.marinum_M               EYSGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH
MUL_3050|M.ulcerans_Agy99           EYSGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH
MAV_2884|M.avium_104                EYAGLLAIHDYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVGCH
MLBr_02072|M.leprae_Br4923          EYAGLLAIHDYHVSRGEPHRNVCLIPSSAHGTNAASAALVGMRVVVVGCH
Mflv_3398|M.gilvum_PYR-GCK          EYAGLLAIQAYHHARGDSGRTVCLIPSSAHGTNAASAAMVGMKVVVVACR
Mvan_3131|M.vanbaalenii_PYR-1       EYAGLLAIRAYHAARGDTDRTVCLIPASAHGTNAASAAMVGMQVVVVACR
MSMEG_3642|M.smegmatis_MC2_155      EYAGLLAIKAYHEARGDADRDICLIPSSAHGTNAASAALAGMRVVVVACR
TH_0290|M.thermoresistible__bu      EYAGLLAIQAYHAERGEPQRDVCLIPSSAHGTNAASAALAGMRVVVVGCR
MAB_2407|M.abscessus_ATCC_1997      EYAGLLAIRQYHIDRGDSGRDVCLIPSSAHGTNAASAALAGMRVVVVACR
                                    **:*****: **  **:. * :****:***********:.**:**** *:

Rv1832|M.tuberculosis_H37Rv         DNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAG
Mb1863|M.bovis_AF2122/97            DNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAG
MMAR_2708|M.marinum_M               DNGDVDLDDLRAKVGEHADRLAALMITYPSTHGVYEHDIADICAAVHDAG
MUL_3050|M.ulcerans_Agy99           DNGDVDLDDLRAKVGEHADRLAALMITYPSTHGVYEHDIADICAAVHDAG
MAV_2884|M.avium_104                DNGDVDLDDLRAKVTDHRDRLSTLMITYPSTHGVYEHDIAEICAAVHDAG
MLBr_02072|M.leprae_Br4923          DNGDVDLDDLRIKLSEHANRLSVLMITYPSTHGVYEHDIAEICAAVHDAG
Mflv_3398|M.gilvum_PYR-GCK          ANGDVDLDDLRAKVTEHADRLSALMITYPSTHGVYEHDIADICAAVHDAG
Mvan_3131|M.vanbaalenii_PYR-1       ANGDVDLDDLRAKVTEHAERLAALMITYPSTHGVYEHDIAEICAAVHDAG
MSMEG_3642|M.smegmatis_MC2_155      ENGDVDLDDLRTKVKEHADRIAALMITYPSTHGVYEHDVADICAAVHDVG
TH_0290|M.thermoresistible__bu      PNGDVDLDDLRVKIAEHSDRLAALMITYPSTHGVYEHDVAEICAAVHDAG
MAB_2407|M.abscessus_ATCC_1997      ENGDVDLDDLRAKIAANASALSAIMITYPSTHGVYEHDIADICAAVHDAG
                                     ********** *:  : . ::.:**************:*:*******.*

Rv1832|M.tuberculosis_H37Rv         GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
Mb1863|M.bovis_AF2122/97            GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MMAR_2708|M.marinum_M               GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MUL_3050|M.ulcerans_Agy99           GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MAV_2884|M.avium_104                GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MLBr_02072|M.leprae_Br4923          GQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
Mflv_3398|M.gilvum_PYR-GCK          GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
Mvan_3131|M.vanbaalenii_PYR-1       GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MSMEG_3642|M.smegmatis_MC2_155      GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
TH_0290|M.thermoresistible__bu      GQVYVDGANLNALVGLARPGRFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
MAB_2407|M.abscessus_ATCC_1997      GQVYVDGANLNALVGLARPGHFGGDVSHLNLHKTFCIPHGGGGPGVGPVA
                                    ********************:*****************************

Rv1832|M.tuberculosis_H37Rv         VRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGL
Mb1863|M.bovis_AF2122/97            VRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGL
MMAR_2708|M.marinum_M               VRSHLAPFLPGHPFAPELPQGDPVSAAPYGSASILPITWAYIRMMGADGL
MUL_3050|M.ulcerans_Agy99           VRSHLAPFLPGHPFAPGLPQGDPVSAAPYGSASILPITWAYIRMMGADGL
MAV_2884|M.avium_104                VRSHLAPFLPGHPHAPELPQGHPVSSAPYGSASILPISWAYIRMMGADGL
MLBr_02072|M.leprae_Br4923          VRSHLVSFLPGHPFAPELPQGQPVSSAPYGSASLLPITWAYIRMMGADGL
Mflv_3398|M.gilvum_PYR-GCK          VRAHLAPYLPGHPLAAELSDDHTVSAAPYGSASILPITWAYIRMMGAAGL
Mvan_3131|M.vanbaalenii_PYR-1       VRSHLAPYLPGHPLADELSDEHTVSAAPYGSASILPITWAYIRMMGAQGL
MSMEG_3642|M.smegmatis_MC2_155      VRAHLAPYLPGHPLADELSDDHTVSAAPYGSASILPITWMYIRMMGADGL
TH_0290|M.thermoresistible__bu      VGVHLAKYLPGHPLADELGDTLTVSAAPYGSASILPITWMYIRMMGAQGL
MAB_2407|M.abscessus_ATCC_1997      VRSHLAQYLPGHPYAEELPAGAPVSSAPYGSASILPITWAYIRMMGPDGL
                                    *  **. :***** *  *    .**:*******:***:* ******. **

Rv1832|M.tuberculosis_H37Rv         RAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGI
Mb1863|M.bovis_AF2122/97            RAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGI
MMAR_2708|M.marinum_M               RAASLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRGITKATGV
MUL_3050|M.ulcerans_Agy99           RAASLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRGIPKATGV
MAV_2884|M.avium_104                RAASLTAITSANYIARRLDEYFPVLYTGENGMVAHECILDLRPITKATGV
MLBr_02072|M.leprae_Br4923          RTASLTAIASANYIARRLDKYFPVLYTGENGMVAHECILDLRPITKSVGV
Mflv_3398|M.gilvum_PYR-GCK          RSATLVAIASANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKATGV
Mvan_3131|M.vanbaalenii_PYR-1       RSASLVAIASANYIARRLDEYYPVLYTGENGMVAHECILDLRAITKATGV
MSMEG_3642|M.smegmatis_MC2_155      RAATLTAIASANYVARRLDEYFPVLYTGENGMVAHECILDLRGITKATGV
TH_0290|M.thermoresistible__bu      RTATLTAIASANYIARRLDEYFPVLYTGENGMVAHECILDLRPLTKATGV
MAB_2407|M.abscessus_ATCC_1997      RAASLTAIASANYLARRLDEYYPVLYTGDNGMVAHECILDLREITKNTGV
                                    *:*:*.**:****:*****:*:******:************* :.* .*:

Rv1832|M.tuberculosis_H37Rv         TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGI
Mb1863|M.bovis_AF2122/97            TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGI
MMAR_2708|M.marinum_M               TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCDAMISI
MUL_3050|M.ulcerans_Agy99           TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCDAMISI
MAV_2884|M.avium_104                TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESETLTEVDAFCDAMIAI
MLBr_02072|M.leprae_Br4923          TVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESLAEIDAFCEAMIAI
Mflv_3398|M.gilvum_PYR-GCK          TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLSEIDAFCDAMIAI
Mvan_3131|M.vanbaalenii_PYR-1       TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIAI
MSMEG_3642|M.smegmatis_MC2_155      TVDDVAKRLADFGFHAPTMSFPVSGTLMVEPTESESLAEVDAFCDAMIAI
TH_0290|M.thermoresistible__bu      TVDDVAKRLADFGFHAPTMSFPVAGTLMVEPTESESLAEIDAFCEAMIAI
MAB_2407|M.abscessus_ATCC_1997      TVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIAI
                                    ***********:***********.***********:*:*:****:***.*

Rv1832|M.tuberculosis_H37Rv         RAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTA
Mb1863|M.bovis_AF2122/97            RAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTA
MMAR_2708|M.marinum_M               RAEIDRVGSGQWPVDDNPLRGAPHTAQCLLVGEWDHPYTREEAAYPLGTA
MUL_3050|M.ulcerans_Agy99           RAEIDRVGSGQWPVDDNPLRGAPHTAQCLLVGEWDHPYTREEAAYPLGTA
MAV_2884|M.avium_104                RGEIDRVGAGEWPVEDNPLRGAPHTAECLVTTDWDHPYSREQAAYPLGKD
MLBr_02072|M.leprae_Br4923          RGEIARVGAGEWSVEDNPLRGAPHTAECLLASDWDHPYTREEAAYPLGKA
Mflv_3398|M.gilvum_PYR-GCK          RAEIDRVGSGEWPVDDNPLRGAPHTAESLLVEEWTHPYTREQAAYPLGKG
Mvan_3131|M.vanbaalenii_PYR-1       RGEIDKVGSGMWSVDDNPLRGAPHTAESLLVEDWHHPYTREQAAYPLGKG
MSMEG_3642|M.smegmatis_MC2_155      RGEIDRVGSGEWPVDDNPLRGAPHTADCLLVADWNRPYTREEAAYPLGKG
TH_0290|M.thermoresistible__bu      RREIDRVGSGEWPVDDNPLRNAPHTAECLIAGEWNHPYTREQAAYPLGTG
MAB_2407|M.abscessus_ATCC_1997      KSEIDKVGSGVWPAQDNPLRGAPHTAESLIADEWHHPYTRAEAAYPLGRG
                                    : ** :**:* *..:*****.*****:.*:. :* :**:* :******  

Rv1832|M.tuberculosis_H37Rv         FRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA-
Mb1863|M.bovis_AF2122/97            FRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA-
MMAR_2708|M.marinum_M               FRPKVWPAARRIDGAYGDRNLVCSCPPVEAFA-
MUL_3050|M.ulcerans_Agy99           FRPKVWPAARRIDGAYGDRNLVCSCPPVEAFA-
MAV_2884|M.avium_104                FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA-
MLBr_02072|M.leprae_Br4923          FRPKVWPPVRRIDGVYGDRNLVCSCLPVEAFV-
Mflv_3398|M.gilvum_PYR-GCK          FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA-
Mvan_3131|M.vanbaalenii_PYR-1       FRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA-
MSMEG_3642|M.smegmatis_MC2_155      WRPKVWPPVRRIDGAYGDRNLVCSCPPVEAFA-
TH_0290|M.thermoresistible__bu      FRPKVWPPVRRIDGAYGDRNLVCSCPPIEAYA-
MAB_2407|M.abscessus_ATCC_1997      FRPKVWPPVRRIDGAYGDRNLVCSCPPIEAFAQ
                                    :******..*****.********** *:**:.