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MDEAHPAHPADAGRPGGPIQGARRGAAMTPITALPTELAAMREVVETLAPIERAAGEPGEHKAAEWIVER LRTAGAQDARIEEEQYLDGYPRLHLKLSVIGVAAGVAGLLSRRLRIPAALAGVGAGLAIADDCANGPRIV RKRTETPRTTWNAVAEAGDPAGQLTVVVCAHHDAAHSGKFFEAHIEEVMVELFPGIVERIDTQLPNWWGP ILAPALAGVGALRGSRPMMIAGTVGSALAAALFADIARSPVVPGANDNLSAVALLVALAERLRERPVKGV RVLLVSLGAEETLQGGIYGFLARHKPELDRDRTYFLNFDTIGSPELIMLEGEGPTVMEDYFYRPFRDLVI RAAERADAPLRRGIRSRNSTDAVLMSRAGYPTACFVSINRHKSVANYHLMSDTPENLCYETVSHAVTVAE SVIRELAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1770 | - | - | 100% (428) | hypothetical protein Rv1770 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1799 | - | 0.0 | 100.00% (428) | hypothetical protein Mb1799 |
| M. gilvum PYR-GCK | Mflv_0190 | - | 3e-06 | 23.55% (310) | aminopeptidase Y |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4212c | - | 1e-07 | 22.07% (367) | lipoprotein aminopeptidase LpqL |
| M. marinum M | MMAR_2647 | - | 1e-178 | 77.81% (401) | hypothetical protein MMAR_2647 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2315 | lpqL | 2e-06 | 26.99% (289) | PROBABLE LIPOPROTEIN AMINOPEPTIDASE LPQL |
| M. ulcerans Agy99 | MUL_3123 | - | 1e-177 | 77.31% (401) | hypothetical protein MUL_3123 |
| M. vanbaalenii PYR-1 | Mvan_0716 | - | 8e-06 | 25.50% (298) | aminopeptidase Y |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4212c|M.abscessus_ATCC_199 MALFSARGLARGCSLLAI---------AAVASCCAHPST--PGAAAPTAP
Mvan_0716|M.vanbaalenii_PYR-1 ---MTSRRSGLG-ALVAV---------CALVVSCSS------GLQAPVAG
Mflv_0190|M.gilvum_PYR-GCK ---MTVAGRANVVAVTRRRVAAVLAVAVLAVAGCGRETAPAPQPQPDPTP
TH_2315|M.thermoresistible__bu ---LTAGALMTAMAVFG----------TAVVGGCSRSTQTEPVPGAAP-A
Rv1770|M.tuberculosis_H37Rv ---------------------------------MDEAHPAHPADAGRPGG
Mb1799|M.bovis_AF2122/97 ---------------------------------MDEAHPAHPADAGRPGG
MMAR_2647|M.marinum_M --------------------------------------------------
MUL_3123|M.ulcerans_Agy99 --------------------------------------------------
MAB_4212c|M.abscessus_ATCC_199 NPNLAADLARSVTVDAMMVHLQQLQQVADANG-GNRAEGTSGYDASADYV
Mvan_0716|M.vanbaalenii_PYR-1 ---LGPELADKVTIDGVYGHLGKFQEIADAND-GNRADGSPGYQASVDYV
Mflv_0190|M.gilvum_PYR-GCK AGEFADELSGKVTADAMMTHLTRLQEIADAHG-GNRALGSPGYRESVDYV
TH_2315|M.thermoresistible__bu AADFAAELRDRISGDAVFAHLTELQRIADEHG-GNRALGTPGYDASVDYV
Rv1770|M.tuberculosis_H37Rv PIQGARRGAAMTPITALPTELAAMREVVETLAPIERAAGEPGEHKAAEWI
Mb1799|M.bovis_AF2122/97 PIQGARRGAAMTPITALPTELAAMREVVETLAPIERAAGEPGEHKAAEWI
MMAR_2647|M.marinum_M ----------MSPITVLPTELATMRTIIETLAPIERAAGDPGEHEAALRI
MUL_3123|M.ulcerans_Agy99 ----------MSPITVLPTELATMRTIIETLAPIERAAGDPGEHEAALRI
. : .* :: : : :** * .* :. :
MAB_4212c|M.abscessus_ATCC_199 AKVLKDR-GFEVQTPELSRLKVLSEGKPLVDIGGRPYALDQASYFAQTPK
Mvan_0716|M.vanbaalenii_PYR-1 AQLLRDK-GFDVQTPEFQRLSGSEGGKPSLTVAGRQFRVDQASLLLTTPP
Mflv_0190|M.gilvum_PYR-GCK ADILRDK-GFDVETQDFVVKIPWAD-EPSLTVAGNKVEARPMMYTIGTDG
TH_2315|M.thermoresistible__bu VDVLRDS-GFEVETPEFEVRLPFAE-DPEVTVGGAPVSAKPLLFTIGTGP
Rv1770|M.tuberculosis_H37Rv VERLRTAGAQDARIEEEQYLDGYPRLHLKLSVIGVAAGVAGLLSRRLRIP
Mb1799|M.bovis_AF2122/97 VERLRTAGAQDARIEEEQYLDGYPRLHLKLSVIGVAAGVAGLLSRRLRIP
MMAR_2647|M.marinum_M VDWLDAAGAQHARIEEEQFYDGYPQLHARLSAVGVGAAAAGLISRRLRGI
MUL_3123|M.ulcerans_Agy99 VDWLDAAGAQHARIEEEQFYDGYPQLHARLSAVGVGAAAAGLISRRLRGI
.. * . ... : . : *
MAB_4212c|M.abscessus_ATCC_199 GGLK--ANIIRPSGKASGCAAADYGTLKVDGQIAVVDGTGCSVVDKHNVA
Mvan_0716|M.vanbaalenii_PYR-1 GGLK--AITLRPR-RPAGCTAADYGDVSVAKAIAVVDDAGCSIVTKQRVA
Mflv_0190|M.gilvum_PYR-GCK DGVSGPIVVAKSED-TPGCTADDYDGLPVDGAIVLVDRGSCPFGGKQAIA
TH_2315|M.thermoresistible__bu DGVSGPLVPARADDDSPGCTADDYDGLPVDGAVVLVDRGHCPFGDKQAAA
Rv1770|M.tuberculosis_H37Rv AALAG---------VGAGLAIADDCANGPRIVRKRTETPRTTWNAVAEAG
Mb1799|M.bovis_AF2122/97 AALAG---------VGAGLAIADDCANGPRIVRKRTETPRTTWNAVAEAG
MMAR_2647|M.marinum_M AALAG---------VGAGLAIADDCSNGVRIARKSLQQRRTTWNVVAEAG
MUL_3123|M.ulcerans_Agy99 AALAG---------VGAGLAIADDCSNGVRIARKSLQQRRPTWNVAAEAG
.: .* : * : . .
MAB_4212c|M.abscessus_ATCC_199 KQKGASAVLVAMQA------GAGEGLFTPNYYEQLSIPVGIIDSGVDTLL
Mvan_0716|M.vanbaalenii_PYR-1 VAEGAVGMLVVSQASPSRPVGAAPTLFSPGYYHDLTVPVGVIDPAADAAL
Mflv_0190|M.gilvum_PYR-GCK AERGAVALIVANNED-----GDEFGGGTLGGDTDVKIPVVGVTREAGEQL
TH_2315|M.thermoresistible__bu AERGAVALIVANTVD-----EEEMGG-TLGERTEVEIPVVSVSKSEGARL
Rv1770|M.tuberculosis_H37Rv DPAGQLTVVVCAHHD----AAHSGKFFEAHIEEVMVELFPGIVERIDTQL
Mb1799|M.bovis_AF2122/97 DPAGQLTVVVCAHHD----AAHSGKFFEAHIEEVMVELFPGIVERIDTQL
MMAR_2647|M.marinum_M DLDGQETVVVCAHHD----AAHSGKFFEPGYQRFFVERFPGIVERIDTSL
MUL_3123|M.ulcerans_Agy99 DLDGQKTVVVCAHHD----AAHSGKFFEPGYQRFFVERFPGIVERIDTSL
* ::* . . : . *
MAB_4212c|M.abscessus_ATCC_199 RRNSS-PVNLVLDMNVAKVRSHSVIAQTTTGDHANVVLTGAHLDSVSKGP
Mvan_0716|M.vanbaalenii_PYR-1 RRTES-PVTLVLDNRPVMTTSRNVVAQTRTGDARNVVMVGAHLDSVRSGP
Mflv_0190|M.gilvum_PYR-GCK RREPGAPAVLNLNAGVRVERTQNVIAQTTTGSTADVVMLGAHLDSVSEGP
TH_2315|M.thermoresistible__bu RERPG-PTAITLEAGVETKRTRNVIAQTSTGATSDVVMIGAHLDGVPDGP
Rv1770|M.tuberculosis_H37Rv PNWWG-PILAPALAGVGALRGSRPMMIAGTVGSALAAALFADIARSPVVP
Mb1799|M.bovis_AF2122/97 PNWWG-PILAPALAGVGALRGSRPMMIAGTVGSALAAALFADIARSPVVP
MMAR_2647|M.marinum_M PNWWP-SILAPIVAGVGAWRGSRKTMIAGAAMSAIGVAAFTDIARSPIVP
MUL_3123|M.ulcerans_Agy99 PNWWP-SILAPIVAGVGAWRGSRKTMIAGAAMSAIGVAAFTDIARSPIVP
. . : : . :.: *
MAB_4212c|M.abscessus_ATCC_199 GINDNGTGVAAVLETALQLGPKPVVNNAVRFAFWTAEEDGLAGSLEYAKS
Mvan_0716|M.vanbaalenii_PYR-1 GINDNGSGVATVLETAVQLGGEPQTANAVRFTFWGAEEVSMDGSKTYLRS
Mflv_0190|M.gilvum_PYR-GCK GINDNGSGVAAILETAVQLGGAPEVANAVRFAFWGAEEDGLRGSNNYVGT
TH_2315|M.thermoresistible__bu GMNDNGSGVAAVLETARQLGSAPDIANAVRFGFWGAEEVGLRGSRAYLAS
Rv1770|M.tuberculosis_H37Rv GANDNLSAVALLVALAERLRERPVKGVRVLLVSLGAEETLQGGIYGFLAR
Mb1799|M.bovis_AF2122/97 GANDNLSAVALLVALAERLRERPVKGVRVLLVSLGAEETLQGGIYGFLAR
MMAR_2647|M.marinum_M GANDNLSAVALLVALAERLRERPVPGVRVLLVSLGAEEQLQGGVYGFVAR
MUL_3123|M.ulcerans_Agy99 GANDNLSAVALLVALAERLRERPVPGVRVLLVSLGAEEQLQGGVYGFVAR
* *** :.** :: * :* * * : *** * :
MAB_4212c|M.abscessus_ATCC_199 RSPEELNDIALYLNFDMLGSPNAGYFVLDGDQSAAKPDPNRPPLDVPEGS
Mvan_0716|M.vanbaalenii_PYR-1 LSKEQLDDIALYLNFDMVGSPNPGYFTDDGDQSTQTG----PVAPVPDGS
Mflv_0190|M.gilvum_PYR-GCK LDTETLKDIALYLNFDMLGSPNPGYFTYDGNQSTAPD-PRIGVPRVPEGS
TH_2315|M.thermoresistible__bu LDVEELKDIAVYLNLDMVGSPNPGYFTYDGDLSSPPD-PNRPAPRVPEGS
Rv1770|M.tuberculosis_H37Rv HKPELDRDRTYFLNFDTIGSPE--LIMLEG-----------------EGP
Mb1799|M.bovis_AF2122/97 HKPELDRDRTYFLNFDTIGSPE--LIMLEG-----------------EGP
MMAR_2647|M.marinum_M HKPELDRDHTYFLNFDTIGSPE--LIMLEG-----------------EGT
MUL_3123|M.ulcerans_Agy99 HKPELDRDHTYFLNFDTIGSPE--LIMLEG-----------------EGT
. * * : :**:* :***: : :* :*.
MAB_4212c|M.abscessus_ATCC_199 AGIERTFAGYLNLAGKRPAAEEFSGRSDYGPFMAAGIPVGGISSGALERM
Mvan_0716|M.vanbaalenii_PYR-1 AGIERTLAARLNTAGVRPADMPLTRTTDYGPFLAAGIPVGGLTTGSSQLK
Mflv_0190|M.gilvum_PYR-GCK AGIERTLAAYLDRAGKPARDTSFDGRSDYDAFTKAGVPAGGLFSGAEAKM
TH_2315|M.thermoresistible__bu AGVERTLVAALADEDIEPDDVNLEGRSDNDSFTLAGIPAGGLFTGGSGEK
Rv1770|M.tuberculosis_H37Rv TVMEDYFYRPFRDLVIRAAERADAP-------LRRGIRSRNSTDAVLMSR
Mb1799|M.bovis_AF2122/97 TVMEDYFYRPFRDLVIRAAERADAP-------LRRGIRSRNSTDAVLMSR
MMAR_2647|M.marinum_M TVMEDYYHRPFRDLVARAADRAEAP-------LRRGMRSRNSTDAVIMSR
MUL_3123|M.ulcerans_Agy99 TVMEDYYHRPFRDLVARAADRAEAP-------LRRGMRSRNSTDAVIMSR
: :* : . *: . .
MAB_4212c|M.abscessus_ATCC_199 SGPEAKTWEGHAGQPFDPNYHGPKDTLANVGKTALGINGPAVAFAVGTYA
Mvan_0716|M.vanbaalenii_PYR-1 TEVQARLWGGQAGVAFDPNYHTPRDDIDNVDRGALAIMASSAAFAIGTYA
Mflv_0190|M.gilvum_PYR-GCK SSEEAELWGGEADQPFDPNYHKASDTLEHIDRTALQIHGSGVAYAAGLYA
TH_2315|M.thermoresistible__bu TEEQAERWGGTAGEPFDPNYHKEGDDLDNIDRTALAVNAAAAAYAVGMYA
Rv1770|M.tuberculosis_H37Rv AGYPTACFVSINRHKSVANYHLMSDTPENLCYETVSHAVTVAESVIRELA
Mb1799|M.bovis_AF2122/97 AGYPTACFVSINRHKSVANYHLMSDTPENLCYETVSHAVTVAESVIRELA
MMAR_2647|M.marinum_M AGYPTACFSSIDRHKALSNYHQMSDTPDNVNYETVAHAVTVAESVVRELA
MUL_3123|M.ulcerans_Agy99 AGYPTACFSSIDRHKALSNYHQMSDTPDNVNYETVAHAVTVAESVVRELA
: : : . .*** * :: :: . . . *
MAB_4212c|M.abscessus_ATCC_199 LSTTGPNGVPERKLRRHSPLER-
Mvan_0716|M.vanbaalenii_PYR-1 QSIDGVNGVPARDERDRSAP---
Mflv_0190|M.gilvum_PYR-GCK QDQRGRNGIPVREDRTRHQLTGP
TH_2315|M.thermoresistible__bu QDQRGRNGLPIRDDRTRHQLSNP
Rv1770|M.tuberculosis_H37Rv R----------------------
Mb1799|M.bovis_AF2122/97 R----------------------
MMAR_2647|M.marinum_M R----------------------
MUL_3123|M.ulcerans_Agy99 R----------------------