For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1769 (-)

annotation: hypothetical protein Rv1769
coordinates: 2002626 - 2003870
length: 414

VHEVAAREQRSDGPMRLDAQGRLQRYEEAFADYDAPFAFVDLDAMWGNADQLLARAGDKPIRVASKSLRC
RPLQREILDASERFDGLLTFTLTETLWLAGQGFSNLLLAYPPTDRAALRALGELTAKDPDGAPIVMVDSV
EHLDLIERTTDKPVRLCLDFDAGYWRAGGRIKIGSKRSPLHTPEQARALAVEIARRPALTLAALMCYEAH
IAGLGDNVAGKRVHNAIIRRMQRMSFEELRERRARAVELVREVADIKIVNAGGTGDLQLVAQEPLITEAT
AGSGFYAPTLFDSYSTFTLQPAAMFALPVCRRPGAKTVTALGGGYLASGVGAKDRMPTPYLPVGLKLNAL
EGTGEVQTPLSGDAARRLKLGDKVYFRHTKAGELCERFDHLHLVRGAEVVDTVPTYRGEGRTFL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1769--100% (414)hypothetical protein Rv1769

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1798-0.0100.00% (414) hypothetical protein Mb1798
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0106c-7e-8745.89% (401) hypothetical protein MAB_0106c
M. marinum MMMAR_2646-0.082.61% (414) hypothetical protein MMAR_2646
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3122-0.082.85% (414) hypothetical protein MUL_3122
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv1769|M.tuberculosis_H37Rv         MHEVAAREQRSDGPMRLDAQGRLQRYEEAFADYDAPFAFVDLDAMWGNAD
Mb1798|M.bovis_AF2122/97            MHEVAAREQRSDGPMRLDAQGRLQRYEEAFADYDAPFAFVDLDAMWGNAD
MMAR_2646|M.marinum_M               MHEVG-REQRSDEMARLDEQNRLQRYEEAFADQDAPFAFVDLDAMWSNAG
MUL_3122|M.ulcerans_Agy99           MHEVG-REQRSDEMARLDEQNRLQRYEEAFADQDAPFAFVDLDAMWSNAG
MAB_0106c|M.abscessus_ATCC_199      --------------------MSVRRLAEALRGAPAPLAAVDIDAARSNAA
                                                          ::*  **: .  **:* **:**  .** 

Rv1769|M.tuberculosis_H37Rv         QLLARAGDKPIRVASKSLRCRPLQREILDASERFDGLLTFTLTETLWLAG
Mb1798|M.bovis_AF2122/97            QLLARAGDKPIRVASKSLRCRPLQREILDASERFDGLLTFTLTETLWLAG
MMAR_2646|M.marinum_M               QMLSRAGDKPIRVASKSLRCRPLQREILDSNPRFEGLMTFTLAETLWLAG
MUL_3122|M.ulcerans_Agy99           QMLSRAGDKPIRVASKSLRCRPLQREILDSNPRFEGLMTFTLAETLWLAG
MAB_0106c|M.abscessus_ATCC_199      TLVDAASGLPIRVASKSIRSTALIRKFLEIPG-FHGVLAFTPAEAVHLGD
                                     ::  *.. ********:*. .* *::*:    *.*:::** :*:: *..

Rv1769|M.tuberculosis_H37Rv         QGFSNLLLAYPPTDRAALRALGELTAKDPDGAPIVMVDSVEHLDLIERTT
Mb1798|M.bovis_AF2122/97            QGFSNLLLAYPPTDRAALRALGELTAKDPDGAPIVMVDSVEHLDLIERTT
MMAR_2646|M.marinum_M               QGFDNLLLAYPTTDRTGLRELGELTAENPARAPIVMVDSVEHLDLIDRAT
MUL_3122|M.ulcerans_Agy99           QGFDNLLLAYPTTDRTGLRALGELTAENPARAPIAMVDSVEHLDLIDRAT
MAB_0106c|M.abscessus_ATCC_199      AGVDDVLIAYPSVDRGALATAARHRS--VIRPLIDSADHVRLLAEISRET
                                     *..::*:***..** .*   ..  :     . *  .* *. *  *.* *

Rv1769|M.tuberculosis_H37Rv         DKPVRLCLDFDAGYWRAGGRIKIGSKRSPLHTPEQARALAVEIARRPALT
Mb1798|M.bovis_AF2122/97            DKPVRLCLDFDAGYWRAGGRIKIGSKRSPLHTPEQARALAVEIARRPALT
MMAR_2646|M.marinum_M               DRPVRLCLDLDAGYWRAGGRVKVGPKRSPLHTPEQARELALEIARRPRLR
MUL_3122|M.ulcerans_Agy99           DRPVRLCLDLDAGYWRAGGRVKVGPKRSPLHTPERARELALEIARRPRLR
MAB_0106c|M.abscessus_ATCC_199      NAPIPVCLDIDAGWRPLGGPVHLGPKRSPVRTPEQAAALTDLVCATPGLR
                                    : *: :***:***:   ** :::*.****::***:*  *:  :.  * * 

Rv1769|M.tuberculosis_H37Rv         LAALMCYEAHIAGLGDNVAGKRVHNAIIRRMQRMSFEELRERRARAVELV
Mb1798|M.bovis_AF2122/97            LAALMCYEAHIAGLGDNVAGKRVHNAIIRRMQRMSFEELRERRARAVELV
MMAR_2646|M.marinum_M               LVALMSYEGHIAGFGDQVAGKFAQNAIVRWMQRESFAELRERRARAVELV
MUL_3122|M.ulcerans_Agy99           LVALMSYEGHIAGFGDQVAGKFAQNAIVRWMQRESFAELRERRARAVELV
MAB_0106c|M.abscessus_ATCC_199      LAAVMAYDGQIAGVGDIVPGNPWYQLAVRGMQASSLRELGERLPRVLDAV
                                    *.*:*.*:.:***.** *.*:   :  :* **  *: ** ** .*.:: *

Rv1769|M.tuberculosis_H37Rv         RE------VADIKIVNAGGTGDLQLVAQEPLITEATAGSGFYAPTLFDSY
Mb1798|M.bovis_AF2122/97            RE------VADIKIVNAGGTGDLQLVAQEPLITEATAGSGFYAPTLFDSY
MMAR_2646|M.marinum_M               SE------VAELEIVNAGGTGDLQLVAHESAVTEATAGSGFYAPTLFDSY
MUL_3122|M.ulcerans_Agy99           SE------VAELKIVNAGGTGDLQLVAHESAVTEATAGSGFYAPTLFDSY
MAB_0106c|M.abscessus_ATCC_199      TARLRAAGAPPLELVNSGGTGSLARIAGLGFATELAAGSGFFAPALFDHY
                                            .. :::**:****.*  :*     ** :*****:**:*** *

Rv1769|M.tuberculosis_H37Rv         STFTLQPAAMFALPVCRRPGAKTVTALGGGYLASGVGAKDRMPTPYLPVG
Mb1798|M.bovis_AF2122/97            STFTLQPAAMFALPVCRRPGAKTVTALGGGYLASGVGAKDRMPTPYLPVG
MMAR_2646|M.marinum_M               SAFSLQPAAMFALPICRRPGAKTVTALGGGYLASGVGAKDRMPSPYLPSG
MUL_3122|M.ulcerans_Agy99           SAFSLQPAAMFALPICRRPGAKTVTALGGGYLASGVGAKDRMPSPYLPSG
MAB_0106c|M.abscessus_ATCC_199      RSLHLEPAAAFALPVVRKPAPGLATVLGGGYIASGPAGASRVPVPSWPPG
                                     :: *:*** ****: *:*..  .*.*****:*** .. .*:* *  * *

Rv1769|M.tuberculosis_H37Rv         LKLNALEGTGEVQTPLSGDAARRLKLGDKVYFRHTKAGELCERFDHLHLV
Mb1798|M.bovis_AF2122/97            LKLNALEGTGEVQTPLSGDAARRLKLGDKVYFRHTKAGELCERFDHLHLV
MMAR_2646|M.marinum_M               LKLDPMEGTGEVQTPLSGRAARRLKVGDKVYFRHTKAGELCERFDRLYLV
MUL_3122|M.ulcerans_Agy99           LKLDPLEGTGEVQTPLSGRAARRLKVGDKVYFRHTKAGELCERFDRLYLV
MAB_0106c|M.abscessus_ATCC_199      LSFEASEGAGEVQTPLRG--ARALRIGDAVWFRHAKAGELCEHFTELQLV
                                    *.::. **:******* *  ** *::** *:***:*******:* .* **

Rv1769|M.tuberculosis_H37Rv         RGAEVVDTVPTYRGEGRTFL
Mb1798|M.bovis_AF2122/97            RGAEVVDTVPTYRGEGRTFL
MMAR_2646|M.marinum_M               RGAQVVDVVPTYRGEGRTFL
MUL_3122|M.ulcerans_Agy99           RGAQVVDVVPTYRGEGRTFL
MAB_0106c|M.abscessus_ATCC_199      EGGQHAGSVSTYRGEGMMFL
                                    .*.: .. *.******  **