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M. tuberculosis H37Rv Rv1688 (mpg)

annotation: 3-methyladenine DNA glycosylase
coordinates: 1912979 - 1913590
length: 203

MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRL
YTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADN
GIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1688mpg-100% (203)3-methyladenine DNA glycosylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1714-1e-117100.00% (203) 3-methyladenine DNA glycosylase
M. gilvum PYR-GCKMflv_3514-1e-7173.56% (174) 3-methyladenine DNA glycosylase
M. leprae Br4923MLBr_01351-1e-9278.33% (203) 3-methyladenine DNA glycosylase
M. abscessus ATCC 19977MAB_2352-5e-7368.02% (197) putative 3-methyladenine DNA glycosylase
M. marinum MMMAR_2487mpg3e-9078.33% (203) 3-methyladenine DNA glycosylase, Mpg
M. avium 104MAV_3083-3e-9279.10% (201) 3-methyladenine DNA glycosylase
M. smegmatis MC2 155MSMEG_3759-7e-7767.63% (207) 3-methyladenine DNA glycosylase
M. thermoresistible (build 8)TH_2087-1e-8574.38% (203) POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG
M. ulcerans Agy99MUL_1667mpg2e-9078.33% (203) 3-methyladenine DNA glycosylase
M. vanbaalenii PYR-1Mvan_3295-2e-8070.44% (203) 3-methyladenine DNA glycosylase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3514|M.gilvum_PYR-GCK          ------------------------------------------MIVEVEAY
Mvan_3295|M.vanbaalenii_PYR-1       -------------MSRAELEVDPLTAARLLLGAKLVGRGVTATIVEVEAY
MSMEG_3759|M.smegmatis_MC2_155      -------------MSVDLLTGDPIAAARRLIGAHLVGRDVTATIVEVEAY
TH_2087|M.thermoresistible__bu      VNAGDARGGGGGCGDADVLAVDPVTAAHRLLGAVLVGRGVTATIVEVEAY
Rv1688|M.tuberculosis_H37Rv         -------------MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAY
Mb1714|M.bovis_AF2122/97            -------------MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAY
MMAR_2487|M.marinum_M               -------------MSAEQLLVDPVSAAHRLLGATIAARGVCGVIVEVEAY
MUL_1667|M.ulcerans_Agy99           -------------MSAEQLLVDPVSAAHRLLGATIAARGVCGVIVEVEAY
MAV_3083|M.avium_104                --MVEAG--RRLRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAY
MLBr_01351|M.leprae_Br4923          --MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAY
MAB_2352|M.abscessus_ATCC_1997      -------------MSAEILNTHPVKAARRLLGATIESRGVSAVIVEVEAY
                                                                               :******

Mflv_3514|M.gilvum_PYR-GCK          GGPDDGPWPDPAAHSFRGPGLRNSVMFGPPGRLYTYRSHGIHVCANVVCA
Mvan_3295|M.vanbaalenii_PYR-1       GGPVDGPWPDAAAHSFRGPGLRNSVMFGPPGRLYTYRSHGIHVCANVACA
MSMEG_3759|M.smegmatis_MC2_155      GGPPDGPWPDAASHSFRGPGVRNSVMFGPPGHLYTYRSHGIHVCANVVCG
TH_2087|M.thermoresistible__bu      GGPPDGPWPDAAAHSYRGRNGRNAVMFGPAGRLYTYRSHGIHVCANVACA
Rv1688|M.tuberculosis_H37Rv         GGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACG
Mb1714|M.bovis_AF2122/97            GGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACG
MMAR_2487|M.marinum_M               GGVPDGPWPDAAAHSYRGPSARNRVMFGPPGRLYTYRSHGIHVCANVACG
MUL_1667|M.ulcerans_Agy99           GGVPDGPWPDAAAHSYRGPSARNRVMFGPPGRLYTYRSHGIHVCANVACG
MAV_3083|M.avium_104                GGVPDGPWPDAAAHSYKGLRARNFVMFGPPGRLYTYRSHGIHVCANVSCG
MLBr_01351|M.leprae_Br4923          GGVPDGPWPDAAAHSYHGRNDRNAVMFGPPGRLYTYCSHGIHVCANVSCG
MAB_2352|M.abscessus_ATCC_1997      GGVPDGPWPDPAAHSFRGPTKRNRVMFGPAGHLYVYQSHGIHMCANVVCG
                                    **  ******.*:**::*   ** *****.*:**.* *****:**** *.

Mflv_3514|M.gilvum_PYR-GCK          ADGVAAAVLLRAAIVDTGHESAWARRGPAVRESALARGPGNLCSALGITM
Mvan_3295|M.vanbaalenii_PYR-1       TDGVAGAVLLRAAAIDTGHDTARGRRGVSVTEAALARGPGNLCSALGITM
MSMEG_3759|M.smegmatis_MC2_155      YDGVAGAVLLRAAVVTDGVDSAQRRRGPQVPPKGLARGPGNLCSALGIVM
TH_2087|M.thermoresistible__bu      EDGVAAAVLLRAAVVESGAGVAAERRGPAIKPAGWARGPGNLCAALGITM
Rv1688|M.tuberculosis_H37Rv         PDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITM
Mb1714|M.bovis_AF2122/97            PDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITM
MMAR_2487|M.marinum_M               PDGTAAAVLLRACAIGRGTDVARSRRGGLVATAALGRGPGNLCSALGITM
MUL_1667|M.ulcerans_Agy99           PDGTAAAVLLRACAIGRGTDVARSRRGGLVATAALGRGPGNLCSALGITM
MAV_3083|M.avium_104                PDGTAAAVLLRAAALEDGTDVARGRRGELVHTAALARGPGNLCAAMGITM
MLBr_01351|M.leprae_Br4923          PDGTAAAVLIRAGALENGADVARSRRGASVRTVALARGPGNLCSALGITM
MAB_2352|M.abscessus_ATCC_1997      PDGVAGGVLMRAAAIVDGAPLCWQRRPTARDDAGLARGPGNLGAALAITL
                                     **.*..**:**  :  *   .  **       . .****** :*:.*.:

Mflv_3514|M.gilvum_PYR-GCK          DDNGTDLFDPSSPIRLVLGDLRVGDT----GPRVGVSKAADRPWRMWLPG
Mvan_3295|M.vanbaalenii_PYR-1       DDNGSDLFDPSAPVQVTLGELRVGES----GPRVGVSKAADRPWRMWLPG
MSMEG_3759|M.smegmatis_MC2_155      EDNGIDLFDDASPVRLSLDGRAPGSADVLEGPRVGVSQAADRPWRFWLAS
TH_2087|M.thermoresistible__bu      DDNGLDLFDPAAPVRLRLAASPPAPVS---GPRVGVSKAADRPWRFWVAD
Rv1688|M.tuberculosis_H37Rv         ADNGIDLFDPSSPVRLRLNDTHRARS----GPRVGVSQAADRPWRLWLTG
Mb1714|M.bovis_AF2122/97            ADNGIDLFDPSSPVRLRLNDTHRARS----GPRVGVSQAADRPWRLWLTG
MMAR_2487|M.marinum_M               DDNGIDLFDPASPVTLQLHEPIAAVS----GPRVGVSRAADRPWRLWSAD
MUL_1667|M.ulcerans_Agy99           DDNGIDLFDPASPVTLQLHEPIAAVS----GPRVGVSRAADRPWRLWSAD
MAV_3083|M.avium_104                ADNGIDLFDPDSPVTLRLHEPLTAVC----GPRVGVSQAADRPWRLWLPG
MLBr_01351|M.leprae_Br4923          DDNGIDVFAADSPVTLVLNEAQEAMS----GPRVGISHAADRPWRLWLPG
MAB_2352|M.abscessus_ATCC_1997      EDGGLDVFSPCSPVRVTLNRQRTALS----GPRVGVSVAADRPWRFWLPG
                                     *.* *:*   :*: : *     .      *****:* *******:* ..

Mflv_3514|M.gilvum_PYR-GCK          HREVSAYRRSPRAPAPGESD--
Mvan_3295|M.vanbaalenii_PYR-1       HPEVSAYRRSPRAPIPGDSD--
MSMEG_3759|M.smegmatis_MC2_155      TPEVSAYRRSPRAPAPGSSD--
TH_2087|M.thermoresistible__bu      RPEVSSYRRSPRAPAPGDSD--
Rv1688|M.tuberculosis_H37Rv         RPEVSAYRRSSRAPARGASD--
Mb1714|M.bovis_AF2122/97            RPEVSAYRRSSRAPARGASD--
MMAR_2487|M.marinum_M               RPEVSAYRRSPRAPALGASD--
MUL_1667|M.ulcerans_Agy99           RPEVSAYRRSPRAPALGASD--
MAV_3083|M.avium_104                RPEVSAYRRSPRAPAPGTSD--
MLBr_01351|M.leprae_Br4923          RPEVSTYRRSPRAPAPGASD--
MAB_2352|M.abscessus_ATCC_1997      YPEVSAYRRSPRAPQPDTGLYA
                                      ***:****.***  . .