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WCPSVSLSIWANAWLAGKAAPDDVLDALSLWAPTQSVAAYDAVAAGHTGLPWPDVHDAGTVSLLQTLRAA VGRRRLRGTINVVLPVPGDVRGLAAGTQFEHDALAAGEAVIVANPEDPGSAVGLVPEFSYGDVDEAAQSE PLTPELCALSWMVYSLPGAPVLEHYELGDAEYALRSAVRSAAEALSTIGLGSSDVAKPRGLVEQLLESSR QHRVPDHAPSRALRVLENAAHVDAIIAVSAGLSRLPIGTQSLSDAQRATDALRPLTAVVRSARMSAVTAI LHSAWPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1486c | - | - | 100% (288) | hypothetical protein Rv1486c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1522c | - | 1e-163 | 99.65% (288) | hypothetical protein Mb1522c |
| M. gilvum PYR-GCK | Mflv_3655 | - | 2e-92 | 61.07% (298) | hypothetical protein Mflv_3655 |
| M. leprae Br4923 | MLBr_01804 | - | 1e-126 | 76.67% (300) | hypothetical protein MLBr_01804 |
| M. abscessus ATCC 19977 | MAB_2720 | - | 4e-69 | 49.82% (285) | hypothetical protein MAB_2720 |
| M. marinum M | MMAR_2292 | - | 1e-132 | 76.27% (316) | hypothetical protein MMAR_2292 |
| M. avium 104 | MAV_3292 | - | 1e-129 | 78.32% (309) | hypothetical protein MAV_3292 |
| M. smegmatis MC2 155 | MSMEG_3153 | - | 1e-98 | 65.19% (293) | hypothetical protein MSMEG_3153 |
| M. thermoresistible (build 8) | TH_1377 | - | 4e-60 | 59.72% (211) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1494 | - | 1e-116 | 73.99% (296) | hypothetical protein MUL_1494 |
| M. vanbaalenii PYR-1 | Mvan_2757 | - | 8e-94 | 61.43% (293) | hypothetical protein Mvan_2757 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1486c|M.tuberculosis_H37Rv --------------MWCPSVSLSIWANAWLAG--KAAPDDVLDALSLWAP
Mb1522c|M.bovis_AF2122/97 --------------MWCPSVSLSIWANAWLAG--KAAPDDVLDALSLWAP
MAV_3292|M.avium_104 --------------MWCPSVSLSLWANAWLAG--KAAPDDVLDALSVWAP
MLBr_01804|M.leprae_Br4923 --------------MWCPSVSLSVWANAWLAG--KAAPDDLLDALSLWTP
MMAR_2292|M.marinum_M MIRLSRGEQLHCETMWCPSVSLSMWANAWLAG--KAAPDDLLDALSLWAP
MUL_1494|M.ulcerans_Agy99 MAAQPRQSWSSCD-LSGPDTPGPIRPLTPLPRQSQAAPDDLLDALSLWAP
Mflv_3655|M.gilvum_PYR-GCK --------------MWCPSVSLSVWANAWLAG--AAAPDDVLDALSLWTP
Mvan_2757|M.vanbaalenii_PYR-1 --------------MWCPSVSLSMWANAWLAG--AAAPDDVLDALSQWTP
TH_1377|M.thermoresistible__bu --------------------------------------------------
MSMEG_3153|M.smegmatis_MC2_155 --------------MWCPSATLSMWANAWLAG--VAAPDDVLDALSLWAP
MAB_2720|M.abscessus_ATCC_1997 --------------MANPSVSLAVWASAWLAG--RAAPDDVIDALIAWAP
Rv1486c|M.tuberculosis_H37Rv TQSVAAYDAVAAGHTGLPWPDVHDAGTVSLLQTLRAAVGRRR--------
Mb1522c|M.bovis_AF2122/97 TQSVAAYDAVAAGHTGLPWPDVHDAGTVSLLQTLRAAVGRRR--------
MAV_3292|M.avium_104 KQSVTAYDAVAAGHTGLPWPDVHDAGTVTLLQTLRAAIGVPVGSGL----
MLBr_01804|M.leprae_Br4923 MQSVAAYDAVAAGHTGLPWPDIHDAGTVSLLQTLRTAVGRPTKSTPNDPH
MMAR_2292|M.marinum_M TQSVTAYDAVAAGHTGLPWPDVHNVGTVSLLQTLRAAVGRSTAAAPSTPG
MUL_1494|M.ulcerans_Agy99 TQSVTAYDAVAAGHTGLPWPDVHNVGTVSLLQTLLAAVGRSTAAAPPTPD
Mflv_3655|M.gilvum_PYR-GCK RHSVTAYDSAAAERTGLSWPDLDDAASVSLLQTLRTASARGAN-------
Mvan_2757|M.vanbaalenii_PYR-1 RHSVTAYDSVAAERTGLSWPDLDDAASVSLLQTVRTAAGQGTP-------
TH_1377|M.thermoresistible__bu --------------------------------------------------
MSMEG_3153|M.smegmatis_MC2_155 THSVTAYDSAAADRTGLPWPELEDSGSMSLLQTLRTAVGRTSS-------
MAB_2720|M.abscessus_ATCC_1997 RHLVTAYDAVAAGHTGLSWPDMDDNGPIGLLQTIRTATGQPHG-------
Rv1486c|M.tuberculosis_H37Rv -LRGTINVVLPVPGDVRGLAAGTQFEHDALAAGEAVIVANPEDPGSAVGL
Mb1522c|M.bovis_AF2122/97 -LRGTINVVLPVPGDVRGLAAGTQFEHDALAAGEAVIVANPEDPGSAVGL
MAV_3292|M.avium_104 -MRGTINVVLPVPGDVRGLAPGTQFEQDALAAGEAVIVSNPHQPGAAVGL
MLBr_01804|M.leprae_Br4923 RLRGTINVVLPVPGDVHGLVTGTQFEHDALAASEAVIITNPHDSSTAVGL
MMAR_2292|M.marinum_M GLCGTINVVLPVPGDVRGLSAGTQFARDALASGEALIVSNPDDPGTAIGL
MUL_1494|M.ulcerans_Agy99 GLFGTINVVLPVPGDVRGLSAGTQFARGALASGEALIVSNPDDPGTAIGL
Mflv_3655|M.gilvum_PYR-GCK --RPTISLALPVPGDVRGLPAGTQFGRDAIAAGEAVVVGGLDG---AIGL
Mvan_2757|M.vanbaalenii_PYR-1 --HPPVTLALPVPGDVRGLPPGTQFGRDAIAAGEAVIVNGPAG---SIGL
TH_1377|M.thermoresistible__bu -------VALPVPGDVRGLPAGTQFQQDAIAVGEAVIVGGAAADGTAVGL
MSMEG_3153|M.smegmatis_MC2_155 --MPAITIAQPVPGDVRGLPAGTQFQRDALAVGEAVVVTHDDLD--GVGL
MAB_2720|M.abscessus_ATCC_1997 --LPDIHVILPAPGDPRGLPAGTQFQRDAMEASEAIILSDRQNDSTAIGL
: *.*** :** .**** :.*: .**::: .:**
Rv1486c|M.tuberculosis_H37Rv VPEFSYGD--VDEAA---QSE-PLTPELCALSWMVYSLPG-APVLEHYEL
Mb1522c|M.bovis_AF2122/97 VPEFSYGD--VDEAA---QSE-PLTPELCALSWMVYSLPG-APVLEHYEL
MAV_3292|M.avium_104 VPEFCYAD--DDDGS---QDY-ALT-ELCALSWTVYSLPG-APVLDHHEL
MLBr_01804|M.leprae_Br4923 VPEYSYSN--PEQYT---NSEETRLSELSALSWVVYSLPG-VPLFDHHEL
MMAR_2292|M.marinum_M VPEFSYSD--ADEAG---DDE-TGTPELSALAWTVYSLPG-APAVDHYEL
MUL_1494|M.ulcerans_Agy99 VPEFSYSD--ADEAA---DDE-TGTPELSALAWTVYSLPG-APAFDHYEL
Mflv_3655|M.gilvum_PYR-GCK VPDFEYEDSFPDSPG--LEADFEYEAEVTGLSWTVYSFSA-VPPPGHFDL
Mvan_2757|M.vanbaalenii_PYR-1 VPDFEYRDSFPDSVD--AEDEFEFEAELIGLSWTVYSFSS-APPAGHFDL
TH_1377|M.thermoresistible__bu VPEFEYPEDHPDDF---AESDGGDETAPTGLSWTVYSLPT-VPPTEHVDL
MSMEG_3153|M.smegmatis_MC2_155 VPEFTYDEFGDTDLDSVFEPESRFEPEPRALSWTVYSVPR-IPPGAYIEL
MAB_2720|M.abscessus_ATCC_1997 VPAVEYDE----------DRD-----ETTGLFWTVYSLPAKIPPQPAQDL
** * : : .* * ***.. * :*
Rv1486c|M.tuberculosis_H37Rv GDAEYALRSAVRSAAEALSTIGLGS--SDVAKPRGLVEQLLESSRQHRVP
Mb1522c|M.bovis_AF2122/97 GDAEYALRSAVRSAAEALSTIGLGS--SDVANPRGLVEQLLESSRQHRVP
MAV_3292|M.avium_104 GDAEYTLRSAVRSAAETLGAIGLGSAASDVDDPRGLVEQLLESARQHRIP
MLBr_01804|M.leprae_Br4923 GDAEYALRSAVRSAADALGTIELNSATADITDPRGLVEQLLESSRQHRVP
MMAR_2292|M.marinum_M ADAEYALRSAVRSAADALSAIGLGSAASDVANPRGLVEQMLESSRQHRIP
MUL_1494|M.ulcerans_Agy99 ADAEYALRSAVRSAADALSAIGLGSAANDVANPRGLVEQMLESSRQHRIP
Mflv_3655|M.gilvum_PYR-GCK GESEYQLRDAVRSAADTLGALRAGASGGEIADPRRLVEQVLDSLSMHRVP
Mvan_2757|M.vanbaalenii_PYR-1 GEAEYELRDAVRSAADALGALRAGASGGEIDDPSSLVEQVLDSTRLHRIP
TH_1377|M.thermoresistible__bu GDAEYGLRTAVRSAAQALDALQVGIAGTDLDDPRLLVEQIVESHRLHRIP
MSMEG_3153|M.smegmatis_MC2_155 GEAEYELRDAVRSAADALVTLRAG-AGFDVEDPRGMVEQILAAGRAHRVP
MAB_2720|M.abscessus_ATCC_1997 GEAEFQLRQAVRAATATLGRLDRAVGATEAD-PRALVEEVLSTLRGHRLP
.::*: ** ***:*: :* : : * :**::: : **:*
Rv1486c|M.tuberculosis_H37Rv DHAPSRALRVLENAAHVDAIIAVSAGLSR-----------------LPIG
Mb1522c|M.bovis_AF2122/97 DHAPSRALRVLENAAHVDAIIAVSAGLSR-----------------LPIG
MAV_3292|M.avium_104 DHAPSRALRVLENAAHVDAIIAVSAGLSRS--DSPDRFAAPIAAGLEPLG
MLBr_01804|M.leprae_Br4923 DHAPSRALRVLENAAHVDAIISVSTGLTP-------------------IG
MMAR_2292|M.marinum_M DHAPSRALRVLENAAHVDAIIAVSSGLSRLPDSAPEHMAHRMAAGLEPVG
MUL_1494|M.ulcerans_Agy99 DHAPSRALRVLENAAHVYAIIAVSSGLSRLPDSAPEHMAHRIVAGLEPVG
Mflv_3655|M.gilvum_PYR-GCK DHAPPRAVRVLENAAHVDAIITVSSGLIP-------------------SG
Mvan_2757|M.vanbaalenii_PYR-1 DHAPARAVRVLENAAHVDAIITVSSGLIP-------------------IG
TH_1377|M.thermoresistible__bu AHAPGRALRVLETASHVDAIITVSSGLSP-------------------IG
MSMEG_3153|M.smegmatis_MC2_155 DHAPTRAVRVLENAAHVDAIIAVSAGLIP-------------------SG
MAB_2720|M.abscessus_ATCC_1997 DYAPHRAIRVLDSANQVEAIATAAAEILE---------------------
:** **:***:.* :* ** :.:: :
Rv1486c|M.tuberculosis_H37Rv TQSLSDAQRATDALRPLTAVVRSARMSAVTAILHSAWPD
Mb1522c|M.bovis_AF2122/97 TQSLSDAQRATDALRPLTAVVRSARMSAVTAILHSAWPD
MAV_3292|M.avium_104 TQSSSEARIAGDALRPLTAVVRSARMAAVTAILHSAWGD
MLBr_01804|M.leprae_Br4923 THSLSDIEIASNALRPLTAVVRSARMAAVNAILHSAWPD
MMAR_2292|M.marinum_M TQSSSEVQIATDALRPLNAVVRSARMAAISAILHSAWSD
MUL_1494|M.ulcerans_Agy99 TQSSSEVQIATDALRPLNAVVRSARMAAISAILHSAWSN
Mflv_3655|M.gilvum_PYR-GCK LQSSSEVQIAGDALRPLISVVRSARLAAVDAILHSAWQN
Mvan_2757|M.vanbaalenii_PYR-1 LQSSSEVQLASDVLRPLSTVVRSARLAAVDAILHSAWRS
TH_1377|M.thermoresistible__bu LQSSSEVRIADDALRPLAHVVRTARLAAVNAIIASAWR-
MSMEG_3153|M.smegmatis_MC2_155 LQSSSEVQIADSALRPLTRVVRSARMAALEAILHSAWRS
MAB_2720|M.abscessus_ATCC_1997 LPGALDDGAVSDALRPLILVVREARMAAASAIIGAAR--
. : . ..**** *** **::* **: :*