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M. tuberculosis H37Rv Rv1448c (tal)

annotation: transaldolase
coordinates: 1626959 - 1628080
length: 373

TAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAA
RGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLF
IKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVD
TEIDKRLDRIGSRQALELRGQAGVANARLAYATYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYS
DTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVR
KFEASWNELLQETRAHLDTAAQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1448ctal-100% (373)transaldolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1483ctal0.099.73% (373) transaldolase
M. gilvum PYR-GCKMflv_3693-1e-16578.96% (366) transaldolase
M. leprae Br4923MLBr_00582tal1e-16778.92% (370) transaldolase
M. abscessus ATCC 19977MAB_2760-1e-15775.34% (373) transaldolase
M. marinum MMMAR_2253tal1e-18084.99% (373) transaldolase Tal
M. avium 104MAV_3328tal1e-17082.87% (356) transaldolase
M. smegmatis MC2 155MSMEG_3102tal1e-16579.67% (369) transaldolase
M. thermoresistible (build 8)TH_0338tal1e-17282.07% (368) PROBABLE TRANSALDOLASE TAL
M. ulcerans Agy99MUL_1843tal1e-18084.72% (373) transaldolase
M. vanbaalenii PYR-1Mvan_2719-1e-16980.43% (368) transaldolase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3102|M.smegmatis_MC2_155      ---MAQNPNLAALSAAGVSVWLDDLSRDRLQTGNLTELINTRSVVGVTTN
Mvan_2719|M.vanbaalenii_PYR-1       ---MTQNPNLAALAAAGVSVWLDDLSRDRLQTGNLQELIDTRSVVGVTTN
Mflv_3693|M.gilvum_PYR-GCK          ---MTQNPNLAALSEAGVSVWLDDLSRERLQTGNLQELIDTKSIVGVTTN
MAB_2760|M.abscessus_ATCC_1997      MSTSDQNANLAELSEAGVAVWLDDLSRDRLNSGNLAELIATRSVVGVTTN
TH_0338|M.thermoresistible__bu      ---MAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQQLIDTRCVVGVTTN
Rv1448c|M.tuberculosis_H37Rv        MTA--QNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTN
Mb1483c|M.bovis_AF2122/97           MTA--QNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTN
MMAR_2253|M.marinum_M               MAS--QNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTN
MUL_1843|M.ulcerans_Agy99           MAS--QKPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTN
MLBr_00582|M.leprae_Br4923          MTSKIQNPNLAALSAAGVSVWLDDLSRDRLQSGNLQKLIDTKSVVGVTTN
MAV_3328|M.avium_104                -------------------MWLDDLSRDRLRSGNLQELIDTKCVVGVTTN
                                                       :*******:**.:*** :** *:.:******

MSMEG_3102|M.smegmatis_MC2_155      PSIFQAALSKGTAYDAQVNELAARGADVDATIRTVTTDDVRNACDLLAKE
Mvan_2719|M.vanbaalenii_PYR-1       PSIFQAALSKGHAYDAQVKELAERGADVDATIRTVTTDDVRNACDVLAKQ
Mflv_3693|M.gilvum_PYR-GCK          PSIFQAALSAGEAYDDQIRELAERGADVDATIRTVTTDDVRNACDVFAKI
MAB_2760|M.abscessus_ATCC_1997      PAIFQAALSKGHAYDAQIAELAERGADVDSAIRTATTDDVRAACDVLAAQ
TH_0338|M.thermoresistible__bu      PSIFQAALSKGHSYDEQIRELAARGADVDSAIRTVTTDDVREACDVLRPQ
Rv1448c|M.tuberculosis_H37Rv        PSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQ
Mb1483c|M.bovis_AF2122/97           PSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQ
MMAR_2253|M.marinum_M               PSIFQKALSEGHDYDAQVAELAERGADVDATIRTVTTDDVRNACDVLAPR
MUL_1843|M.ulcerans_Agy99           PSIFQKALSEGHDYDAQVAELAERGADVDATIRTVTTDDVRNACDVLAPR
MLBr_00582|M.leprae_Br4923          PSIFQKAFANGHAYDAQIAELAKRGANVDVTVRTVTTDDVRHACDVLACE
MAV_3328|M.avium_104                PSIFQKAFAEGHAYDSQIAELAARGADVDATIRTVTTDDVRNACDVLTRE
                                    *:*** *:: *  ** *: *** ***:** ::**.****** ***::   

MSMEG_3102|M.smegmatis_MC2_155      YEASDGVDGRVSIEVDPRLAHDTDKTILQAIELWKIVDRPNLLIKIPATM
Mvan_2719|M.vanbaalenii_PYR-1       YELSDGVDGRVSIEVDPRLAHDTDKTILQAIELWKIVDRPNLLIKIPATM
Mflv_3693|M.gilvum_PYR-GCK          YEQSGGVDGRVSIEVDPRLAHDTDKTILQAIELWKIVDRPNLLIKIPATE
MAB_2760|M.abscessus_ATCC_1997      YEASGGVDGRVSIEVDPRLAHDTDKTILQAIELWKIVDRPNLLIKIPATK
TH_0338|M.thermoresistible__bu      WEASDGVDGRVSIEVDPRLAHDTDKTILQAIELWKIVDRPNLFIKIPATK
Rv1448c|M.tuberculosis_H37Rv        WEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATK
Mb1483c|M.bovis_AF2122/97           WEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATK
MMAR_2253|M.marinum_M               WEASGGVDGRVSIEVDPRLAHETDKTIQQAVELWKIVDRPNLLIKIPATK
MUL_1843|M.ulcerans_Agy99           WEASGGVDGRVSIEVDPRLAHETDKTIQQAVELWKIVDRPNLLIKIPATK
MLBr_00582|M.leprae_Br4923          WEASHGKDGRVSIEVDPRLAHDTDKTIAQAVELWRIVDHPNLFIKIPATK
MAV_3328|M.avium_104                WENSDGVDGRVSIEVDPRLAGDTDKTIAQAVELWKIVDRPNLFIKIPATQ
                                    :* * * ************* :*:*** **:***:***:***:****** 

MSMEG_3102|M.smegmatis_MC2_155      AGLPAISAVIAEGISVNVTLIFSVERHRLVMDAYLEGLEKAKEAGHDLSK
Mvan_2719|M.vanbaalenii_PYR-1       AGLPAITAVIAEGISVNVTLIFSVERHRLVMDAYLAGLEKAKEAGHDLSK
Mflv_3693|M.gilvum_PYR-GCK          AGVPAIASVLAEGISVNVTLIFSVERYRLVMDAYLQGLEKAKEAGHDLSR
MAB_2760|M.abscessus_ATCC_1997      AGLPAITAVIAEGISVNVTLIFSVQRHKEVMDAYLSGLEAAKEAGRDLSK
TH_0338|M.thermoresistible__bu      AGLPAITAVLAEGVSVNVTLIFSVERYREVMDAYLAGLEAAKQAGHDLSK
Rv1448c|M.tuberculosis_H37Rv        AGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSK
Mb1483c|M.bovis_AF2122/97           AGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSK
MMAR_2253|M.marinum_M               AGLPAIAAVLAEGISVNVTLIFSVDRHRGVMDAYLTGMEKAAQAGHDLSK
MUL_1843|M.ulcerans_Agy99           AGLPAIAAVLAEGISVNVTLIFSVDRHRGVMDAYLTGMEKAAQAGHDLSK
MLBr_00582|M.leprae_Br4923          AGLPAITAVLAEGISVNVTLIFSVQRHREVIDAYLAGIEKAAEAGRDLSK
MAV_3328|M.avium_104                AGLPAITAVLAEGISVNVTLIFSVERYRAVMDAYLAGMEKAREAGHDLSK
                                    **:***::*:***:**********:*:: *:**** *:* * :**:.**:

MSMEG_3102|M.smegmatis_MC2_155      IHSVASFFVSRVDTEIDARLEKIGSDEALALRGKAGVANARLAYAAYEEV
Mvan_2719|M.vanbaalenii_PYR-1       IHSVASFFVSRVDTEIDNRLEKIGSDEALALRGKAGVANARLAYAAYEEV
Mflv_3693|M.gilvum_PYR-GCK          IHSVASFFVSRVDTEIDNRLEKIGSEEALALRGKAGVANARLAYAAYEEI
MAB_2760|M.abscessus_ATCC_1997      IHSVASFFVSRVDTEIDKRLEEIGSGQALSLRGRAGVANARLAYQAYEKV
TH_0338|M.thermoresistible__bu      IHSVASFFVSRVDTEIDNRLEAIGTEQALALRGKAGLANARLAYAAYREV
Rv1448c|M.tuberculosis_H37Rv        IHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYATYREV
Mb1483c|M.bovis_AF2122/97           IHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYAAYREV
MMAR_2253|M.marinum_M               IHSVASFFVSRVDTEIDNRLEQIGSAEALALRGQAGVANARLAYAAYQEV
MUL_1843|M.ulcerans_Agy99           IHSVASFFVSRVDTEIDNRLEQIGSAEALALRGQAGVANARLAYAAYQEV
MLBr_00582|M.leprae_Br4923          IVSVASFFVSRVDTEIDKRLEKLGSEQALALRGQAGVANARLAYAAYQKA
MAV_3328|M.avium_104                IHSVASFFVSRVDTEIDKRLEKIGGERALALRGQAGVANARLAYAAYQEV
                                    * *************** **: :*  .** ***:**:******* :*.: 

MSMEG_3102|M.smegmatis_MC2_155      F-----GSDRFAKLKADGARVQRPLWASTGVKNPEYSDTLYVTELVAPNT
Mvan_2719|M.vanbaalenii_PYR-1       FL----GGERFEPLKSAGARVQRPLWASTGVKNPDYSDTLYVTELVAPNT
Mflv_3693|M.gilvum_PYR-GCK          FL----GGERFAALKDAGARVQRPLWASTGVKNPDYSDTLYVTELVAPDT
MAB_2760|M.abscessus_ATCC_1997      FGSDHHAGHRFAALKDAGARVQRPLWASTGVKNPDYDDTLYVVDLVAPHT
TH_0338|M.thermoresistible__bu      FE----GGSRFEALKADGARVQRPLWASTGVKNPAYPDTLYVTELVAPNT
Rv1448c|M.tuberculosis_H37Rv        FE----DSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHT
Mb1483c|M.bovis_AF2122/97           FE----DSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHT
MMAR_2253|M.marinum_M               FE----GDARYQALKERGARVQRPLWASTGVKNPDYSDTLYVTELVAPHT
MUL_1843|M.ulcerans_Agy99           FE----GDARYQALKERGARVQRPLWASTGVKNPDYSDTLYVTELVAPHT
MLBr_00582|M.leprae_Br4923          FE----GGQRYQTLMARGAQVQRPLWASTGVKNPDYADTLYVTELVAPNT
MAV_3328|M.avium_104                FE----GGQRYQALKADGARVQRPLWASTGVKNPDYSDTLYVTELVAPNT
                                    *      . *:  *   **:************** * *****.:****.*

MSMEG_3102|M.smegmatis_MC2_155      VNTMPEKTLEAVADHGEITGNTIAGTAASSQETFDKLAAIGIDLPDVFRV
Mvan_2719|M.vanbaalenii_PYR-1       VNTMPEKTIEAVADHGVVTGDTITGTAAESQEMFDKLTAIGVDLPDVFTV
Mflv_3693|M.gilvum_PYR-GCK          VNTMPEKTLDAVADHGVVTGDTVTGRAGESQEIFDQLAALGIDLTDVFLV
MAB_2760|M.abscessus_ATCC_1997      VNTMPEKTLEAVADHGVVTGNTIAGTYDGAHAVFHELTRAGIDLDDVFEV
TH_0338|M.thermoresistible__bu      VNTLPEKTLEAVADHGEITGDTVTGRAEESQAIFDQLTAVGIDLDDVFLK
Rv1448c|M.tuberculosis_H37Rv        VNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAV
Mb1483c|M.bovis_AF2122/97           VNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAV
MMAR_2253|M.marinum_M               VNTMPEKTLDAVADHGVVKGDSITGTSGDAQQVFDKLEAIGIDLSDVFDV
MUL_1843|M.ulcerans_Agy99           VNTMPEKTLDAVADHGVVKGDSITGTSGDAQQVFDKLEAIGIDLSDVFDV
MLBr_00582|M.leprae_Br4923          VNTMPETTIDAVADHGVIRGDTISGTTLSSQKVFDSLVAVGVDLIDVFAV
MAV_3328|M.avium_104                VNTMPEKTIDAVADHGVIRGDTVTGTGPDAQRVFDELAAVGVDLPDVFVV
                                    ***:**.*::****** : *::::*    ::  *..*   *:** ***  

MSMEG_3102|M.smegmatis_MC2_155      LEDEGVEKFEKSWQELLDATQGQLDAAKK--
Mvan_2719|M.vanbaalenii_PYR-1       LEDEGVEKFEKSWHELLEATRGQLDSANG--
Mflv_3693|M.gilvum_PYR-GCK          LENEGVEKFEKSWQELLEATQGQLDDKK---
MAB_2760|M.abscessus_ATCC_1997      LETEGVEKFEVAWNELIDATQAQLDAVSTQD
TH_0338|M.thermoresistible__bu      LENEGVQKFEQSWEELLDATREQLDTLGK--
Rv1448c|M.tuberculosis_H37Rv        LEEEGVRKFEASWNELLQETRAHLDTAAQ--
Mb1483c|M.bovis_AF2122/97           LEEEGVRKFEASWNELLQETRAHLDTAAQ--
MMAR_2253|M.marinum_M               LESEGVEKFEASWKELLDATQAQLDALAK--
MUL_1843|M.ulcerans_Agy99           LESEGVEKFEASWKELLDATQAQLDALAK--
MLBr_00582|M.leprae_Br4923          LEHEGVQKFVKSWNELLKETQEQLDSVAK--
MAV_3328|M.avium_104                LENEGVEKFVDSWTELMEETQKQLGSASK--
                                    ** ***.**  :* **:. *: :*.