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M. tuberculosis H37Rv Rv1422 (-)

annotation: hypothetical protein Rv1422
coordinates: 1596881 - 1597909
length: 342

MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADDGGSSGRLRSELDVVPPGDLRMALAALASDSPHG
RLWATILQHRFGGSGALAGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEADVSG
LEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAADLVVLGPGSWFTSVIPHVLVPGL
AAALRATSARRALVLNLVAEPGETAGFSVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATM
LQAEVHFADVARPGTPLHDPGKLAAVLDGVCARDVGASEPPVAATQEIPIDGGRPRGDDAWR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1422--100% (342)hypothetical protein Rv1422

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1457-0.099.71% (342) hypothetical protein Mb1457
M. gilvum PYR-GCKMflv_3713-1e-15782.16% (342) protein of unknown function UPF0052 and CofD
M. leprae Br4923MLBr_00564-1e-16985.71% (350) hypothetical protein MLBr_00564
M. abscessus ATCC 19977MAB_2782c-1e-13671.55% (348) hypothetical protein MAB_2782c
M. marinum MMMAR_2229-1e-17688.57% (350) hypothetical protein MMAR_2229
M. avium 104MAV_3358-1e-17488.89% (351) hypothetical protein MAV_3358
M. smegmatis MC2 155MSMEG_3080-1e-15782.75% (342) hypothetical protein MSMEG_3080
M. thermoresistible (build 8)TH_1323-1e-16081.59% (353) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1816-1e-17688.57% (350) hypothetical protein MUL_1816
M. vanbaalenii PYR-1Mvan_2699-1e-15982.90% (345) protein of unknown function UPF0052 and CofD

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3713|M.gilvum_PYR-GCK          -------------MSPRIVALGGGHGLYATLSAARRLTPHVTAIVTVADD
Mvan_2699|M.vanbaalenii_PYR-1       -------------MSPRIVALGGGHGLYATLSAARRLTPHVTAVVTVADD
Rv1422|M.tuberculosis_H37Rv         -------------MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADD
Mb1457|M.bovis_AF2122/97            -------------MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADD
MMAR_2229|M.marinum_M               ---------MNSPASHSIVALGGGHGLYATLSAARRLTPHVTAIVTVADD
MUL_1816|M.ulcerans_Agy99           ---------MNSPESHSIVALGGGHGLYATLSAARRLTPYVTAIVTVADD
MLBr_00564|M.leprae_Br4923          --------MISPGSPPSIVALGGGHGLYVTLSAARRLTPYVTAIVTVADD
MAV_3358|M.avium_104                ---------MSEPINRGIVALGGGHGLYATLSAARRLTPYVTAVVTVADD
TH_1323|M.thermoresistible__bu      -------------MSPRIVALGGGHGLYATLSAARRITPHVTAVVTVADD
MSMEG_3080|M.smegmatis_MC2_155      -------------MTPRIVALGGGHGLYATLSAARRLTPHVTAVVTVADD
MAB_2782c|M.abscessus_ATCC_199      MSSGIAQDTQLTRREPRIVALGGGHGLYATLSAARRLTHDITAVVTVSDD
                                                     ***********.*******:*  :**:***:**

Mflv_3713|M.gilvum_PYR-GCK          GGSSGRLRNELDVVPPGDLRMALAALASDSPHGRLWATIIQHRFGGSGAL
Mvan_2699|M.vanbaalenii_PYR-1       GGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATIIQHRFGGSGAL
Rv1422|M.tuberculosis_H37Rv         GGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGAL
Mb1457|M.bovis_AF2122/97            GGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGVL
MMAR_2229|M.marinum_M               GGSSGRLRSELDVIPPGDLRMALAALASDSPYGRLWATILQHRFGGSGAL
MUL_1816|M.ulcerans_Agy99           GGSSGRLRSELDVIPPGDLRMALAALASDSPYGRLWATILQHRFGGSGAL
MLBr_00564|M.leprae_Br4923          GGSSGRLRSELGVVPPGDLRMALAALASDSPYGRLWATILQHRFGGSGAL
MAV_3358|M.avium_104                GGSSGRLRSELGVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGAL
TH_1323|M.thermoresistible__bu      GGSSGRLRAELDVIPPGDLRMALAALASDSPHGRLWATIIQHRFGGSGAL
MSMEG_3080|M.smegmatis_MC2_155      GGSSGRLRSELDIVPPGDLRMALAALASDSPHGRLWATIIQHRFGGSGAL
MAB_2782c|M.abscessus_ATCC_199      GGSSGRIRSELGIVPPGDLRMALAALASDSPRGRMWATAIQHRLGGSGGL
                                    ******:* **.::***************** **:*** :***:**** *

Mflv_3713|M.gilvum_PYR-GCK          AGHPIGNLMLAGLNEVLADPVAALDELGRVLGVKGRVLPMCPVGLSIEAD
Mvan_2699|M.vanbaalenii_PYR-1       AGHPIGNLIIAGLNEVLADPVAALDEVGRILGVKGRVLPMCPVGLGIEAD
Rv1422|M.tuberculosis_H37Rv         AGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEAD
Mb1457|M.bovis_AF2122/97            AGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEAD
MMAR_2229|M.marinum_M               AGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPIALQIEAD
MUL_1816|M.ulcerans_Agy99           AGHPIGNLLLAGLSEVLADPVAALDELGRILGVKGRVLPMCPIALQIEAD
MLBr_00564|M.leprae_Br4923          AGHPIGNLMLAGLSEVLADPVAALDEVGRILGVKGRVLPMCPIALQIEAD
MAV_3358|M.avium_104                AGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPIALQIEAD
TH_1323|M.thermoresistible__bu      AGHPIGNLMLAGLNEVLADPVAALDELGRILGVKGRVLPMCPIALQIEAD
MSMEG_3080|M.smegmatis_MC2_155      AGHPIGNLILAGLNEVLADPVAALDELGRILGVKGRVLPMCPIALQIEAD
MAB_2782c|M.abscessus_ATCC_199      AGHPIGNLILAGLTDMLADPVTALDEMGRMLGITGRVLPMCPIPLQIEAD
                                    ********::***.::*****:****:**:**:.********: * ****

Mflv_3713|M.gilvum_PYR-GCK          VVGLESDPRVSRAIRGQVAIATTVGKVRRVRLLPSDPPATPQAIDAIMNA
Mvan_2699|M.vanbaalenii_PYR-1       VVGLESDPRVSRAIRGQVAIATTVGKVRRVRLLPGDPPATHQAVDAIMNA
Rv1422|M.tuberculosis_H37Rv         VSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAA
Mb1457|M.bovis_AF2122/97            VSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAA
MMAR_2229|M.marinum_M               VSGLESDPRMFRLIRGQVAVATTPGKVRRVRLRPADPPATRQAVDAIMAA
MUL_1816|M.ulcerans_Agy99           VSGLESDPRMFRLIRGQVAVATTPGKVRRVRLRPADPPATRQAVDAIMAA
MLBr_00564|M.leprae_Br4923          VSGLEADPRIFRLIRGQVAIASTPGKVRRVRLLPVDPPATRQAVDAIMAA
MAV_3358|M.avium_104                VSGLEADPRMFRVIRGQVAIATTPGKVRRVRLLPDNPPATRQAVDAIMAA
TH_1323|M.thermoresistible__bu      VSGLEADPRMSRVIRGQVAIATTVGKVRRVRLLPGNPPATRQAVDAIMAA
MSMEG_3080|M.smegmatis_MC2_155      VSGLESDPRMSRVIRGQVAIATTVGKVRRVRLLPGDPPATRQAVEAIMSA
MAB_2782c|M.abscessus_ATCC_199      VSGLESDPRMSRVIRGQVALATTPGKVRRVRLHPGNPPATRQAIDAIMAA
                                    * ***:***: * ******:*:* ******** * :**** **::*** *

Mflv_3713|M.gilvum_PYR-GCK          DLVVLGPGSWFTSVIPHVLVPQLAAALQATTARRALVLNLVAEPGETAGF
Mvan_2699|M.vanbaalenii_PYR-1       DLVVLGPGSWFTSVIPHVLVPQLAAALKATTARRALVLNLVAEPGETAGF
Rv1422|M.tuberculosis_H37Rv         DLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGF
Mb1457|M.bovis_AF2122/97            DLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGF
MMAR_2229|M.marinum_M               DLIVLGPGSWFTSVIPHVLVPGLFAALQATSARRALVLNLVAEPGETAGF
MUL_1816|M.ulcerans_Agy99           DLIVLGPGSWFTSVIPHVLVPGLFAALQATSARRALVLNLVAEPGETAGF
MLBr_00564|M.leprae_Br4923          NLVVLGPGSWFTSVIPHVLVPGLVTALRATTARRALVLNLAAGPGETAGF
MAV_3358|M.avium_104                DLVVLGPGSWFTSVIPHVMVPGLAAALRATTARRALVLNLVAEPGETAGF
TH_1323|M.thermoresistible__bu      DLVVLGPGSWFTSVIPHLLVPDLAAALKATAARRALVLNLAAEPGETAGF
MSMEG_3080|M.smegmatis_MC2_155      DLVVLGPGSWFTSVIPHVLVPELAAALRETSARRALVLNLAAEPGETAGF
MAB_2782c|M.abscessus_ATCC_199      DLVVLGPGSWFTSVIPHVLVPELFAALQQTPARKALILNLAPEPGETAGF
                                    :*:**************::** * :**: *.**:**:***.. *******

Mflv_3713|M.gilvum_PYR-GCK          SVERHIHVLAQHAPGFTVHDIIVDSARVTGDRDREQLRRTATIIGADVEF
Mvan_2699|M.vanbaalenii_PYR-1       SVERHIHVLAQHAPGFTVHDIIVDSARVPSEREREQLRRTATILDANVEF
Rv1422|M.tuberculosis_H37Rv         SVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHF
Mb1457|M.bovis_AF2122/97            SVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHF
MMAR_2229|M.marinum_M               SVERHLHVLAQHAPGFTVHDIIIDADRVPSDREKEQLRRTATMLQAEVHF
MUL_1816|M.ulcerans_Agy99           SVERHLHVLAQHAPGFTVHDIIIDADRVPSDREKEQLRRTATMLQAEVHF
MLBr_00564|M.leprae_Br4923          SVERHLHVLAQHAPGFTVHDIIIDADRVPNNREREQLRRAATLLQAEVHF
MAV_3358|M.avium_104                SVERHLHVLAQHAPGFTVHDIIIDAGRVPSEREREQLRRTATLLSAEVHF
TH_1323|M.thermoresistible__bu      SVERHIHVLSQHAPDFTVHDIIVDASRVPSAREREQLSRTAKILRAQVEF
MSMEG_3080|M.smegmatis_MC2_155      SAERHLHVLSQHAPDFRVHDIIVDASRVPSDREREQLSRTANILEARVEF
MAB_2782c|M.abscessus_ATCC_199      SAERHLHVLSQHAPEFGVHDIVVESASADS-TERDHLTRAAALFNAQVQF
                                    *.***:***:**** * ****::::  . .  ::::* *:* :: * *.*

Mflv_3713|M.gilvum_PYR-GCK          ADVSRPGTPLHDPARLAAALDGVRKR------GSTT-----AVAQPTVPT
Mvan_2699|M.vanbaalenii_PYR-1       ADVSRPGTPLHDPARLAAALEGVRKR------GISTNGMTQGVQQPTVPT
Rv1422|M.tuberculosis_H37Rv         ADVARPGTPLHDPGKLAAVLDGVCAR-----DVGASEPPVAATQEIPIDG
Mb1457|M.bovis_AF2122/97            ADVARPGTPLHDPGKLAAVLDGVCAR-----DVGASEPPVAATQEIPIDG
MMAR_2229|M.marinum_M               ADVARPGTPLHDPGKLAAVLDAVRVR-----DRDLTTPPVTSPQEIPIEG
MUL_1816|M.ulcerans_Agy99           ADVARPGTPLHDPGKLAAVLDAVRVR-----DRDLTTPPVTSPQEIPIEG
MLBr_00564|M.leprae_Br4923          VDVARPGTSLHDPGKLATALDGVRVG-----NQDSSAPTVAATEQIRLDG
MAV_3358|M.avium_104                ADVARPGTPLHDPGKLAAALDGVRAA-----RKAPGASPVTATADIRVDG
TH_1323|M.thermoresistible__bu      ADVARPGTPLHDPAKLAEALSGALAHRAVA-SRNSQEPTVPTPVSLTGEG
MSMEG_3080|M.smegmatis_MC2_155      ADVSRPGTPLHDPARLAAVLEGVRLRASAP-GSSVQERTVPTPTARSVDA
MAB_2782c|M.abscessus_ATCC_199      ADVSRPGTHLHDPAKLAAVLDRVRTGGAALGTGTAAGTDAESTVRLAAGG
                                    .**:**** ****.:** .*. .                           

Mflv_3713|M.gilvum_PYR-GCK          PTVN---------GPRGDDPWR
Mvan_2699|M.vanbaalenii_PYR-1       PTAN---------GPRGDDPWR
Rv1422|M.tuberculosis_H37Rv         GR------------PRGDDAWR
Mb1457|M.bovis_AF2122/97            GR------------PRGDDAWR
MMAR_2229|M.marinum_M               GRQQSGGPGAGGNRPKGDDAWR
MUL_1816|M.ulcerans_Agy99           GRQQTGGPGAGGNKPKGDDAWR
MLBr_00564|M.leprae_Br4923          KRPQTGVNGPVGKGPRGDDAWR
MAV_3358|M.avium_104                ASPPAGGNGPAGSGPRGDDAWR
TH_1323|M.thermoresistible__bu      AREQQTLNG-----PRGDDPWR
MSMEG_3080|M.smegmatis_MC2_155      ARRDQAPPD----RSRGDAPWR
MAB_2782c|M.abscessus_ATCC_199      GRTQHG-------SQRGDATWR
                                                   :** .**