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VSPRPGPAGRGPAPCRCADLHSLCVDSHALRRDGMRFLHTADWQLGMTRHFLAGDAQPRYSAARRDAVAG LKALAADVGAEFVVVAGDVFEHNQLAPQIVGQSLEAMRVIGLPVYLLPGNHDPLDASSVYTSTLFRAERP DNVVVLDRAGVHEVRPGVQIVAAPWRSKAPTTDPVAEVLAGLPTDAAIRLLVAHGGVDALDPDHDKPSLI RLAALDDALTRQAIHYVALGDKHSLTQVGSSGRVWYSGAPEVTNFDDVEPDPGHVLVVDIDESDPRHPVT VDARRIGRWRFVTLHHQVDTSRDIADLDLNLDLMTDKDRTVVRLALTGSLTVTDRAALDTCLDKYARLFA WLGLWERHTDLAVIPVDAEFTDLGIGGFAAAAVDELVATARGGDDESAVDAQAALALLLRLADRGAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1277 | - | - | 100% (417) | hypothetical protein Rv1277 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1308 | - | 0.0 | 100.00% (417) | hypothetical protein Mb1308 |
| M. gilvum PYR-GCK | Mflv_2255 | - | 1e-160 | 73.18% (384) | metallophosphoesterase |
| M. leprae Br4923 | MLBr_01119 | - | 0.0 | 82.25% (383) | hypothetical protein MLBr_01119 |
| M. abscessus ATCC 19977 | MAB_1420 | - | 1e-147 | 68.70% (377) | hypothetical protein MAB_1420 |
| M. marinum M | MMAR_4143 | sbcD | 0.0 | 85.38% (383) | DNA repair exonuclease SbcD |
| M. avium 104 | MAV_1427 | - | 0.0 | 83.03% (383) | DNA repair exonuclease |
| M. smegmatis MC2 155 | MSMEG_5004 | - | 1e-170 | 77.40% (385) | DNA repair exonuclease |
| M. thermoresistible (build 8) | TH_1852 | - | 1e-164 | 75.46% (379) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4006 | sbcD | 0.0 | 85.12% (383) | DNA repair exonuclease SbcD |
| M. vanbaalenii PYR-1 | Mvan_4436 | - | 1e-155 | 71.09% (384) | metallophosphoesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2255|M.gilvum_PYR-GCK ----------------------------------MRFLHTADWQLGMTRH
Mvan_4436|M.vanbaalenii_PYR-1 ----------------------------------MRFLHTADWQLGMTRH
Rv1277|M.tuberculosis_H37Rv MSPRPGPAGRGPAPCRCADLHSLCVDSHALRRDGMRFLHTADWQLGMTRH
Mb1308|M.bovis_AF2122/97 MSPRPGPAGRGPAPCRCADLHSLCVDSHALRRDGMRFLHTADWQLGMTRH
MMAR_4143|M.marinum_M ----------------------------------MRFLHTADWQLGMTRH
MUL_4006|M.ulcerans_Agy99 ----------------------------------MRFLHTADWQLGMTRH
MLBr_01119|M.leprae_Br4923 ----------------------------------MRFLHTADWQLGMTRH
MAV_1427|M.avium_104 ----------------------------------MRFLHTADWQLGMTRH
MSMEG_5004|M.smegmatis_MC2_155 ----------------------------------MRFLHTADWQLGMTRH
TH_1852|M.thermoresistible__bu ----------------------------------MRFLHTADWQLGMTRH
MAB_1420|M.abscessus_ATCC_1997 ----------------------------------MKFLHTADWQLGMTRH
*:**************
Mflv_2255|M.gilvum_PYR-GCK YLNGDAQPRYSAARRGAVAALGPLAAQVGAEFVVVSGDVFEHNQLAPREI
Mvan_4436|M.vanbaalenii_PYR-1 YLNGDAQPRYSASRRAAVAALGPLAADVGAEFVVVAGDVFEHNQLAPREV
Rv1277|M.tuberculosis_H37Rv FLAGDAQPRYSAARRDAVAGLKALAADVGAEFVVVAGDVFEHNQLAPQIV
Mb1308|M.bovis_AF2122/97 FLAGDAQPRYSAARRDAVAGLKALAADVGAEFVVVAGDVFEHNQLAPQIV
MMAR_4143|M.marinum_M FLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVAGDVFEHNQLMPQVI
MUL_4006|M.ulcerans_Agy99 FLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVAGDVFEHNQLMPQVI
MLBr_01119|M.leprae_Br4923 FLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVAGDVFEHNQLAPQVV
MAV_1427|M.avium_104 FLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVSGDVFEHNQLPPKVV
MSMEG_5004|M.smegmatis_MC2_155 FLNGEAQPRYSASRREAVASLGEIAKRTGAEFVVVSGDVFEHNQLAPRDV
TH_1852|M.thermoresistible__bu WLNGEAQPRYSAARREAVAELGALAERTGAEFIVVAGDVFDDNQLPPREI
MAB_1420|M.abscessus_ATCC_1997 FLAGEAQPQYSAARREAIASLGEVAVAQGCDFMVVCGDVFESNQLAPRVI
:* *:***:***:** *:* * :* *.:*:**.****: *** *: :
Mflv_2255|M.gilvum_PYR-GCK GTALEAMRAIGVPVYLLPGNHDPLDASSVYTSALFTSERPDNVVVLDTPG
Mvan_4436|M.vanbaalenii_PYR-1 STALEAMRAIPVPVYLLPGNHDPLDASSVYTSALLRSEKPDNVVVLDRPG
Rv1277|M.tuberculosis_H37Rv GQSLEAMRVIGLPVYLLPGNHDPLDASSVYTSTLFRAERPDNVVVLDRAG
Mb1308|M.bovis_AF2122/97 GQSLEAMRVIGLPVYLLPGNHDPLDASSVYTSTLFRAERPDNVVVLDRAG
MMAR_4143|M.marinum_M SQSLEAMRAIGVPVYLLPGNHDPLDASSVYTGALFRTECPDNVVVLDRCG
MUL_4006|M.ulcerans_Agy99 SQSLEAMRAIGVPVYLLPGNHDPLDASSVYTGALFRTECPDNVVVLDRCG
MLBr_01119|M.leprae_Br4923 SQSLEAIRAIGIPVYLLPGNHDPLDASSVYTSALFTAECPDNINVLDRAG
MAV_1427|M.avium_104 GQSLEAMRAIGIPVYLLPGNHDPLDASSVYTSALFTAERPHNVTVLDQAG
MSMEG_5004|M.smegmatis_MC2_155 SQSLEAMRAIGVPVYLLPGNHDPLDASSVYTSALFVAERPDNVVVLDRAG
TH_1852|M.thermoresistible__bu SLSLEAMRGIGVPVYLLPGNHDPLDAASVYTSALFIRECPDNVVVLDRAG
MAB_1420|M.abscessus_ATCC_1997 SQALEVMRGVGVDVYLLPGNHDPLDAASVYTSELFLAEKPANVHVLDTAG
. :**.:* : : *************:****. *: * * *: *** *
Mflv_2255|M.gilvum_PYR-GCK VYEVRPGLELVAAPWFSKAPTTDLVAGALDGLPED-GTTRIVVGHGAVDI
Mvan_4436|M.vanbaalenii_PYR-1 VYEVRPGLELVAAPWSSKAPTTDLVGAVLDGLDASPAVTRVVVGHGAVDI
Rv1277|M.tuberculosis_H37Rv VHEVRPGVQIVAAPWRSKAPTTDPVAEVLAGLPTD-AAIRLLVAHGGVDA
Mb1308|M.bovis_AF2122/97 VHEVRPGVQIVAAPWRSKAPTTDPVAEVLAGLPTD-AAIRLLVAHGGVDA
MMAR_4143|M.marinum_M SHQVRPGVELVAAPWRSKAPTTDLVADVLAGLSEG-AGTRVLVAHGGVDA
MUL_4006|M.ulcerans_Agy99 SHQVRPGVELVAAPWRSKAPTTDLVADVLAGLSEG-AGTRVLVAHGGIDA
MLBr_01119|M.leprae_Br4923 VHQVRPGLEIVAAPWRSKAPTTDLVAEVLGGLTAD-IVTRVLVAHGSIDV
MAV_1427|M.avium_104 VHPVRPGLQLVAAPWRSKVPTTDLVGEVLDGLPET-DDTRILVGHGGVDV
MSMEG_5004|M.smegmatis_MC2_155 VHEVRPGVQIVAAPWRSKAPTSDLIGDVLADLPAD-GVTRVLVGHGGVDI
TH_1852|M.thermoresistible__bu CHEVRPGLQLVAAPWRSKAPTTDLVAEVLADVPAD-GVTRVVVAHGGVDI
MAB_1420|M.abscessus_ATCC_1997 RHQVTPGVELVAVPWRSKAPTHDLVAEQLDGLPAD-GTRRIVVAHGGVDM
: * **:::**.** **.** * :. * .: *::*.**.:*
Mflv_2255|M.gilvum_PYR-GCK LVPDKDRPSLIGLAAVEAALARGAVHYVALGDKHSRMSVGSTGRIWYSGS
Mvan_4436|M.vanbaalenii_PYR-1 LVPDKDRASLIALAGVEAAIARGAVHYVALGDKHSRMSVGSTGRIWYSGS
Rv1277|M.tuberculosis_H37Rv LDPDHDKPSLIRLAALDDALTRQAIHYVALGDKHSLTQVGSSGRVWYSGA
Mb1308|M.bovis_AF2122/97 LDPDHDKPSLIRLAALDDALTRQAIHYVALGDKHSLTQVGSSGRVWYSGA
MMAR_4143|M.marinum_M LDPDPGKPSLIRLAGLEDAVARGMLHYVALGDKHSLTQVGGSGRVWYSGS
MUL_4006|M.ulcerans_Agy99 LDPDPGKPSLIRLAGLEDAVARGMLHYVALGDKHSLTQVGGSGRVWYSGS
MLBr_01119|M.leprae_Br4923 FDPDRDKPSLIRLAGIDDALAGGAVHYVALGDRHSLTQVGSSGRVWYSGS
MAV_1427|M.avium_104 LDPDRDKPSLIRLAKLEDALTRGAVHYVALGDKHSLTQVGRSGRVWYSGS
MSMEG_5004|M.smegmatis_MC2_155 LDPDKNKPSLIRMAAVEDALARGAVHYVALGDKHSRTEVGGSGRVWYSGS
TH_1852|M.thermoresistible__bu LDPDRDKPSLIRLDVLHDALGRGAVHYVALGDKHSRTEVGSSGRVWYSGS
MAB_1420|M.abscessus_ATCC_1997 LDPDPTKPALIALKAVEDAIDRGAIHYVALGDKHSRTQVGSSGRVWYSGA
: ** :.:** : :. *: :*******:** .** :**:****:
Mflv_2255|M.gilvum_PYR-GCK PEVTNYDDIEPDPGQVLVVDIDDTVESRPVTVDARRVGVWRFMSLRHAVD
Mvan_4436|M.vanbaalenii_PYR-1 PEVTNYDDIEPDPGQVLVAEIDEADASRPVQVDAHRVGTWRFMSLRHAVD
Rv1277|M.tuberculosis_H37Rv PEVTNFDDVEPDPGHVLVVDIDESDPRHPVTVDARRIGRWRFVTLHHQVD
Mb1308|M.bovis_AF2122/97 PEVTNFDDVEPDPGHVLVVDIDESDPRHPVTVDARRIGRWRFVTLHHQVD
MMAR_4143|M.marinum_M PEVTNFDDVESDPGHVLVVDIDETDPCRPVSVTARRVGCWRFVTLRREVD
MUL_4006|M.ulcerans_Agy99 PEVTNFDDVESDPGHVLVVDIDETDPCRPVSVTARRVGCWRFVTLRREVD
MLBr_01119|M.leprae_Br4923 PEVTNFDDIESNSGHVLVVEIDENDPRRPVTVTARHVGHWRFFTLHWQVD
MAV_1427|M.avium_104 PEVTNFDDVEADPGHVLIVDIDEADPRRPVSVTARRVGCWRFVTLHRQVD
MSMEG_5004|M.smegmatis_MC2_155 PEVTNYDDIESDPGHVLVVDIDENDARRAVRVESEKVGRWRFVTLRRSVD
TH_1852|M.thermoresistible__bu PEVTNYDDIESDPGHVLLVDIDEDDPQRPVQVEPHRVGRWKFVTLRRTVD
MAB_1420|M.abscessus_ATCC_1997 PEVTNYDDVESDPGHALVVDLDESG---AIRVDAHDVGRWRFVTLRWSVD
*****:**:*.:.*:.*:.::*: .: * .. :* *:*.:*: **
Mflv_2255|M.gilvum_PYR-GCK DNRDIADLDINLDQMPDKETTVIRLGLTGSLTVTDKAALDACLDRYARLF
Mvan_4436|M.vanbaalenii_PYR-1 DKRDVADLDINLDQMPDKERTVIRLGLTGSLTVTDKAALDACLDRYARLF
Rv1277|M.tuberculosis_H37Rv TSRDIADLDLNLDLMTDKDRTVVRLALTGSLTVTDRAALDTCLDKYARLF
Mb1308|M.bovis_AF2122/97 TSRDIADLDLNLDLMTDKDRTVVRLALTGSLTVTDRAALDTCLDKYARLF
MMAR_4143|M.marinum_M TSRDIADLDLNLDLMTDKDRTVVRLALTGSLTVTDRAALDACLDRYARLF
MUL_4006|M.ulcerans_Agy99 TSRDIADLDLNLDLMTDKDRTVVRLALTGSLTVTDRAALDACLDRYARLF
MLBr_01119|M.leprae_Br4923 NGRDIADLDMNLDQMMDKDRSVVRLALTGSLTITDRAVLDACLDRYARLF
MAV_1427|M.avium_104 SSRDIADLDMNLDLMTNKDRTVVRLALTGSLTVTDRAALDACLDKYARLF
MSMEG_5004|M.smegmatis_MC2_155 TDRDIADLDLNLDLLDDKERTVVRLALTGSLTVTDKAKLDECLDRYARLF
TH_1852|M.thermoresistible__bu TNRDIADLDINLDCLADKERTVVRLALTGSLSVTDKAALDACLDKYARRF
MAB_1420|M.abscessus_ATCC_1997 NARDIADLGLNLELFPDKERTVVRLALTGTLSVTDNAGLEECLDKYTRLF
**:***.:**: : :*: :*:**.***:*::**.* *: ***:*:* *
Mflv_2255|M.gilvum_PYR-GCK AALVPWDKQTDIAVMPADGEFDDLGIGGFAAAAVEELVATARSTG-DDAE
Mvan_4436|M.vanbaalenii_PYR-1 AALVPWDNQTDIAVMPADGEFDDLGIGGFAAAAVDELVVAARSAG-EDAE
Rv1277|M.tuberculosis_H37Rv AWLGLWERHTDLAVIPVDAEFTDLGIGGFAAAAVDELVATARGGDDESAV
Mb1308|M.bovis_AF2122/97 AWLGLWERHTDLAVIPVDAEFTDLGIGGFAAAAVDELVATARGGDDESAV
MMAR_4143|M.marinum_M AWLGLWERHTDLAVIPADGEFSDLGIGGFAAAAVDELVATARSGADGSAV
MUL_4006|M.ulcerans_Agy99 AWLGLWERHTDLAVIPADGEFSDLGIGGFAAAAVDELVATARSGADGSAV
MLBr_01119|M.leprae_Br4923 AWLGLWERRSDLAVIPADGEFTDIGIGGFAAAAVDELVATAREGDTESAI
MAV_1427|M.avium_104 AHLRTWDSHTELAVIPADGEFSDLGIGGFAAAAVEELVATARQQDSDTAA
MSMEG_5004|M.smegmatis_MC2_155 AALTTWERHTDIAVIPADGEFDDLGIGGFAAAAVDELVATARSEA-AEAE
TH_1852|M.thermoresistible__bu AALTTWERHTDIAVLPADGEFDDLGVGGFAAAAVDELVALARSEG-EEAD
MAB_1420|M.abscessus_ATCC_1997 ASLRTWERHTDIAVVPADGEFSDLGVGGFAESAIAELKELAAAGG-SSSA
* * *: ::::**:*.*.** *:*:**** :*: ** * :
Mflv_2255|M.gilvum_PYR-GCK DARGALALLLRLTEG--------------GAA-
Mvan_4436|M.vanbaalenii_PYR-1 DARAALALLLRLVEG--------------GAA-
Rv1277|M.tuberculosis_H37Rv DAQAALALLLRLADR--------------GAA-
Mb1308|M.bovis_AF2122/97 DAQAALALLLRLADR--------------GAA-
MMAR_4143|M.marinum_M DAQAALALLLRLTDR--------------GAA-
MUL_4006|M.ulcerans_Agy99 DAQAALALLLRLTDR--------------GAA-
MLBr_01119|M.leprae_Br4923 DAQAALALLLRLADR--------------GVA-
MAV_1427|M.avium_104 DAQGALALLLRLADR--------------GAA-
MSMEG_5004|M.smegmatis_MC2_155 DARAALGLLLRLVD------------RDKGAA-
TH_1852|M.thermoresistible__bu DARGALALLLRLAEGAGE---QQGSRRGEGSAA
MAB_1420|M.abscessus_ATCC_1997 DAQGALSLLLRLTSGAGLGSPAKGGAKKRGAAA
**:.**.*****.. * *