For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1252c (lprE)

annotation: PROBABLE LIPOPROTEIN LPRE
coordinates: 1399296 - 1399904
length: 202

PGVWSPPCPTTPRVGVVAALVAATLTGCGSGDSTVAKTPEATPSLSTAHPAPPSSEPSPPSATAAPPSNH
SAAPVDPCAVNLASPTIAKVVSELPRDPRSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMF
HLGKYIPQGVPDTYGFTGIDTSQCTGDTVALTYASGIGLNNVVKFRWNGGGVELIGNTTGG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1252clprE-100% (202)PROBABLE LIPOPROTEIN LPRE
M. tuberculosis H37RvRv3483c-1e-1727.36% (201) hypothetical protein Rv3483c
M. tuberculosis H37RvRv3193c-3e-0640.74% (54) hypothetical protein Rv3193c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1284clprE1e-119100.00% (202) lipoprotein LprE
M. gilvum PYR-GCKMflv_2224-3e-6463.08% (195) LprE
M. leprae Br4923MLBr_01099-7e-7568.47% (203) putative lipoprotein
M. abscessus ATCC 19977MAB_1402c-1e-4347.06% (187) putative lipoprotein LprE precursor
M. marinum MMMAR_4190lprE4e-8376.73% (202) lipoprotein LprE
M. avium 104MAV_1400-2e-7569.70% (198) LprE protein
M. smegmatis MC2 155MSMEG_5043-1e-6062.90% (186) LprE protein
M. thermoresistible (build 8)TH_2232lprE3e-6161.26% (191) PROBABLE LIPOPROTEIN LPRE
M. ulcerans Agy99MUL_4494lprE2e-8275.74% (202) lipoprotein LprE
M. vanbaalenii PYR-1Mvan_4471-2e-6161.17% (188) LprE

CLUSTAL 2.0.9 multiple sequence alignment


Rv1252c|M.tuberculosis_H37Rv        MPGVWSPPCPTTPRVGV-VAALVAATLTGCGSGDSTVAKTPEATPSLSTA
Mb1284c|M.bovis_AF2122/97           MPGVWSPPCPTTPRVGV-VAALVAATLTGCGSGDSTVAKTPEATPSLSTA
MMAR_4190|M.marinum_M               MRGVKSLPCPVAPLTG--ALALVAATLTGCGSGDSIVAKTPEARTTTSAV
MUL_4494|M.ulcerans_Agy99           MHGVKSLPCPVAPLTG--ALALVAATLTGCGSGDSIVAKTPEVRTTTSAV
MLBr_01099|M.leprae_Br4923          MRDVWSLPCR-KSLLGVAAVVLVSGTLTGCSSGDSTVAKTPVPPSTTTGT
MAV_1400|M.avium_104                ---MWSPPCRTEPLTGSAAVALIAVTLTGCGSGDSTVAKT--PQARTTSE
Mflv_2224|M.gilvum_PYR-GCK          -MPSLTVRCPTVHWPATVLSVAAALTVAACSPGDSTVSKTPEQTAPAAAP
Mvan_4471|M.vanbaalenii_PYR-1       -----MKRAATIG---CVLG-AAALVATACSPGDSTVSKTPDQRTPAAAA
MSMEG_5043|M.smegmatis_MC2_155      -----MKKVAGVV--------LATLALAGCGGGDSTVSKTPG---PTASQ
TH_2232|M.thermoresistible__bu      -----------MSRLGIGSVALAVTLLSGCGAGDSTVSLTPEPTAPSPGA
MAB_1402c|M.abscessus_ATCC_199      ------MVLGTTPPVLTTLLVVLSALACACTGGDSTVSKTPTNTIASPSS
                                                                .*  *** *: *       .  

Rv1252c|M.tuberculosis_H37Rv        HPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDP
Mb1284c|M.bovis_AF2122/97           HPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDP
MMAR_4190|M.marinum_M               NSNEPNAAD-PPPAAAEPPS--SPAPADPCAVNLASPTIAKVVSELPRDP
MUL_4494|M.ulcerans_Agy99           NSNEPNAAD-PPPAAAEPPS--SPSPADPCAVNLASPTIAKVVSELPRDP
MLBr_01099|M.leprae_Br4923          ISTIISSAPSPPFATAAPPT-SNTPPDDPCAVNLASPTIARVVSELPRDP
MAV_1400|M.avium_104                TPSIT--APATPSAAAAQPG-VGQP-ADPCAVNLAAPTIVKVVSELPRDP
Mflv_2224|M.gilvum_PYR-GCK          P------AASPPPQSTGPLPGPAPAD-DPCAIDLAAPEIAQAVSELPRDP
Mvan_4471|M.vanbaalenii_PYR-1       S------ASAQPPAPAGPLPGPAPVD-DPCDIDLAAPEIARAVSELPRDP
MSMEG_5043|M.smegmatis_MC2_155      P------ATAAP-ETTVAAPAPTSAEPDPCTVNLAAPEIARAVSELPRDP
TH_2232|M.thermoresistible__bu      AAPDT--PSAAPPVLETPAP---GAQADPCAVNLVAPEVLRAIAELPPDP
MAB_1402c|M.abscessus_ATCC_199      T-------PPSPGQPSAPVKPKLPSTKDDCAVNLKDPAVASAIALLPPAP
                                               *               * * ::*  * :  .:: **  *

Rv1252c|M.tuberculosis_H37Rv        RSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQ
Mb1284c|M.bovis_AF2122/97           RSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQ
MMAR_4190|M.marinum_M               RSEQPWNPEPLAGNYNECAQLSAVVIRANTNGDNPTTRAVLFHQGKFIPQ
MUL_4494|M.ulcerans_Agy99           RSEQPWNPEPLAGNYNECAQLSAVVIRANTNGDNPTTRAVLFHQGKFIPQ
MLBr_01099|M.leprae_Br4923          RSAQPWNPEPLAGNYNECAQLSAVIIKANTNAVNPTTRAVLFHLGRFIPQ
MAV_1400|M.avium_104                RSQQPWNPEPLAGNYNQCAQLSAVIVKANTNAISPSTRAVLFHLGQFIPQ
Mflv_2224|M.gilvum_PYR-GCK          RSGQGWNPEPLAGNYSECAQLSAVIIKANTNQPNPNTRAVLFHQGKFIPT
Mvan_4471|M.vanbaalenii_PYR-1       RSNQGWNPEPLAGNYNECAQLSAVIVKANTNSENPNTRAVLFHQGKFIPT
MSMEG_5043|M.smegmatis_MC2_155      RSNQAWSPEPIAGNYNECAQLSAVIVRANTNAENPNTRAVLFHLGKFIPT
TH_2232|M.thermoresistible__bu      RSGQAWSSEPIAGNYNECATLSAVIVRANTNAENPNTRAVMFHLGKFIPT
MAB_1402c|M.abscessus_ATCC_199      NNEATWNPVPVAGNYNKCAPLSAIIVAADTHEPQPPTRAVFFHLGGVISH
                                    ..   *.. *:****.:** ***::: *:*:  .* ****:** *  *. 

Rv1252c|M.tuberculosis_H37Rv        GVPDTYGFTGIDTSQCTGDTVALTYASGIG-LNNVVKFRWNGGGVELIGN
Mb1284c|M.bovis_AF2122/97           GVPDTYGFTGIDTSQCTGDTVALTYASGIG-LNNVVKFRWNGGGVELIGN
MMAR_4190|M.marinum_M               GVPDTYGFNGIDTSQCTGDTVALTYATGISGLGSVVKFRWNGNGVELISN
MUL_4494|M.ulcerans_Agy99           GVPDTYGFNGIDTSQCTGDTVALTYATGISGLGSVVKFRWNGNGVELISN
MLBr_01099|M.leprae_Br4923          GVPDTYGFNGIDPAQTTGDTVALTYPSSIDGLATAVRFHWNGNAVELISN
MAV_1400|M.avium_104                GVPDTYGFNGIDPAQTTGDTVALTYPGGLSGLSTDVKFHWNGNAVELIGN
Mflv_2224|M.gilvum_PYR-GCK          GVPDTYGFNGLDTTQTTGDTVALKYSSGMPGLDSVVRFRWNGSGVELIGN
Mvan_4471|M.vanbaalenii_PYR-1       GVPDTYGFNGLDSTQTTGDTVALKYSGGVPGLDSIVKFRWNGSGVELIGN
MSMEG_5043|M.smegmatis_MC2_155      GVPDTYGFNDIDKTQSTGDTVALQYSGGFHGLPSTVRFRWNGSGVELMGN
TH_2232|M.thermoresistible__bu      GVPDTYGFNAIDTSAGSGDTVALRYDSGIEGLSGVVKFRWNGNGVELVGN
MAB_1402c|M.abscessus_ATCC_199      GVPDTYGYNAIDLSASTLDTVVLNFSNGIPGLESVVSFRWNGTGVEKVQQ
                                    *******:. :* :  : ***.* :  ..  *   * *:*** .** : :

Rv1252c|M.tuberculosis_H37Rv        TTGG
Mb1284c|M.bovis_AF2122/97           TTGG
MMAR_4190|M.marinum_M               KTG-
MUL_4494|M.ulcerans_Agy99           KTG-
MLBr_01099|M.leprae_Br4923          IAGG
MAV_1400|M.avium_104                TPAH
Mflv_2224|M.gilvum_PYR-GCK          TPG-
Mvan_4471|M.vanbaalenii_PYR-1       TAR-
MSMEG_5043|M.smegmatis_MC2_155      VG--
TH_2232|M.thermoresistible__bu      TG--
MAB_1402c|M.abscessus_ATCC_199      AGQ-