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MPSIPQSLLWISLVVLWLFVLVPMLISKRDAVRRTSDVALATRVLNGGAGARLLKRGGPAAGHRWGYLPP EGQGDDPDWKPEEDWRDDPVEDGFADVEHDIDEDQEADDARRRGAVVMKVAAPQTAGADEPDYLDVDVVE EDSEALPVGAGAAVGESADEADAEAADGVAGHADPEADPVEYEYEYEYVEDTCGLELEEDDQEAPPTVAS GTSRRRRFDTKTAAAVSARKYTFRKRALIVMAVILVGSAAAAFELTPVAWWICGSATGVTVLYLAYLRRQ TRIEEKVRRRRMQRIARARLGVENTRDREYDVVPSRLRRPGAVVLEIDDEDPIFTHLESAAPIRNYGWPR DLPRAVGQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0996 | - | - | 100% (358) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1023 | - | 0.0 | 99.44% (358) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1900 | - | 4e-85 | 50.38% (397) | hypothetical protein Mflv_1900 |
| M. leprae Br4923 | MLBr_00185 | - | 1e-122 | 65.93% (361) | hypothetical protein MLBr_00185 |
| M. abscessus ATCC 19977 | MAB_1089 | - | 2e-82 | 51.23% (365) | hypothetical protein MAB_1089 |
| M. marinum M | MMAR_4518 | - | 1e-125 | 61.23% (405) | hypothetical protein MMAR_4518 |
| M. avium 104 | MAV_1105 | - | 1e-116 | 64.49% (352) | hypothetical protein MAV_1105 |
| M. smegmatis MC2 155 | MSMEG_5468 | - | 1e-97 | 52.31% (411) | hypothetical protein MSMEG_5468 |
| M. thermoresistible (build 8) | TH_3622 | - | 8e-93 | 48.84% (430) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4690 | - | 1e-125 | 60.70% (402) | hypothetical protein MUL_4690 |
| M. vanbaalenii PYR-1 | Mvan_4830 | - | 6e-95 | 54.75% (400) | hypothetical protein Mvan_4830 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1900|M.gilvum_PYR-GCK MPSIPQSLLWISLVVLWLFVLVPMLISKRDAVRRTSDVALATRVLNSGAR
Mvan_4830|M.vanbaalenii_PYR-1 MPSIPQSLLWISLVVLWLFVLVPMLINKRDAVRRTSDVALATRVLNSGAG
TH_3622|M.thermoresistible__bu MPSIPQSLLWISLVILWLFVLVPMLISKRDAVRRTSDVALATRVLTDGRN
MSMEG_5468|M.smegmatis_MC2_155 MPSIPQSLLWISLVVLWLFVLVPMLISKRESVRRTSDVALATRVLNSGRN
Rv0996|M.tuberculosis_H37Rv MPSIPQSLLWISLVVLWLFVLVPMLISKRDAVRRTSDVALATRVLNGGAG
Mb1023|M.bovis_AF2122/97 MPSIPQSLLWISLVVLWLFVLVPMLISKRDAVRRTSDVALATRVLNGGAG
MLBr_00185|M.leprae_Br4923 MPSIPQSLLWISLVVLWLFVLVPMLISKRDVVRRISDVALATRVLNGVAG
MAV_1105|M.avium_104 -------------MVLWLFVLVPMLVSKRDAVRRTSDVALATRVLNGGAN
MMAR_4518|M.marinum_M MPSIPQSLLWISLVVLWLFVLVPMLISKREAVRRTSDVALATRVLNGGAS
MUL_4690|M.ulcerans_Agy99 MPSIPQSLLWISLVVLWLFVLVPMLISKREAVRRTSDVALATRVLNGGAS
MAB_1089|M.abscessus_ATCC_1997 MPSIPQSVLWIGLVVLWLFVLVPMLINKRDVVKRTSDVALATRVLN-GKA
::**********:.**: *:* **********.
Mflv_1900|M.gilvum_PYR-GCK SRLRRRG-PAAGHRS----------DPDWSPSDEDAAADVD---------
Mvan_4830|M.vanbaalenii_PYR-1 ARLRRRGGPAAGHRS----------DPDWRPSASDLDEDLDDV-------
TH_3622|M.thermoresistible__bu SRLMRRG-PAAGHRS----------DPDWQAFDDQLEDDFDDAFD-----
MSMEG_5468|M.smegmatis_MC2_155 AQRLRRG-PAAGHNS----------DPHWRPTPDHLDDEFEAELE-----
Rv0996|M.tuberculosis_H37Rv ARLLKRGGPAAGHRWGYLPPEGQGDDPDWKPEEDWRDDPVEDGFADVEHD
Mb1023|M.bovis_AF2122/97 ARLLKRGGPAAGHRWGYLPPEGQGDDPDWKPEEDWRDDPVEGGFADVEHD
MLBr_00185|M.leprae_Br4923 ARLLKRGGPATGHRS----------DHNWELDEDWRQNPVDGEFADADQD
MAV_1105|M.avium_104 SRLVKRGGPAAGHRS----------DPHWTRPEDSDADLDEEHDVAADEP
MMAR_4518|M.marinum_M SRLVKRGGPAAGHRS----------DPDWKHQRDWDHEAHDDDDDEDDAE
MUL_4690|M.ulcerans_Agy99 SRLVKRGGPAAGHRS----------DPDWKRQREWDHEAHDDDDDEDDAE
MAB_1089|M.abscessus_ATCC_1997 AKLLRRTGPAAGHRS----------DPDFRREDIDELDDEDEEESTGVIA
:: :* **:**. * .: :
Mflv_1900|M.gilvum_PYR-GCK ---------------VDDVPSRAVVMVAAEGEDANT---EPDYLDVDVVE
Mvan_4830|M.vanbaalenii_PYR-1 ---------------EEKAPSRAVVMVAGAAGGADA---EPDYLDVDVVE
TH_3622|M.thermoresistible__bu -------------DREAELPTRRPVVVAASKVSPDADEDEPDYLDVDVIE
MSMEG_5468|M.smegmatis_MC2_155 -------------ETEPSRPPKRAVVVAAAATEPAE----PDYLDVDIVE
Rv0996|M.tuberculosis_H37Rv --------IDE--DQEADDARRRGAVVMKVAAPQTAGADEPDYLDVDVVE
Mb1023|M.bovis_AF2122/97 --------IDE--DQEADDARRRGAVVMKVAAPQTAGADEPDYLDVDVVE
MLBr_00185|M.leprae_Br4923 --------IGEEQDQNVDDTQRTRPVVMEVAVAELTGT---DYLDVDVV-
MAV_1105|M.avium_104 --------GDQDDDADTDELSRRRPVVMRMATAEPAEP---DYLDVDVV-
MMAR_4518|M.marinum_M PETDQIPELAHGDDEVAQDTGSQGAVIMKVAATRDAAVDEPDYLDVDVVE
MUL_4690|M.ulcerans_Agy99 PETDQIPELAHGDDEVAQDTGSQGAVIMKVAATRDTAVDEPDYLDVDVVE
MAB_1089|M.abscessus_ATCC_1997 S----------EPSEDDKDAARAVKAMAVRKVRPEKKVEADEPVDVDVVD
. : : :***::
Mflv_1900|M.gilvum_PYR-GCK -DSGALPIADITA-EEEVAPVAENDEVT--STFDDVESEPVAD-EPQERH
Mvan_4830|M.vanbaalenii_PYR-1 -DSGAQPVAELAA-DAQQAESVAAESNE--LTLDFAEADELDD-APEDRD
TH_3622|M.thermoresistible__bu EDSGALPVGASAA-EEPGSDEQRVESAAGVDEVDDVEVDAEAEGEAEAEA
MSMEG_5468|M.smegmatis_MC2_155 EDSGALPLGATHAPEIEDVEVVEEVEPADDAQTDQLSLDLDEAGDEAGDE
Rv0996|M.tuberculosis_H37Rv EDSEALPVGAGAA------------------VGESADEADAEAADGVAGH
Mb1023|M.bovis_AF2122/97 EDSEALPVGAGAA------------------VGESADEADAEAADGVAGH
MLBr_00185|M.leprae_Br4923 EDSVALPIEDSAD------------------VTESVLLAVGEGGS---PG
MAV_1105|M.avium_104 EDSAALPVGASGS------------------AAENNDEQPAEDDD---VD
MMAR_4518|M.marinum_M EDSGVLCLGPGAR------------------SAQEQPTPRAAGTAVTDAE
MUL_4690|M.ulcerans_Agy99 EDSGVLCLGPGAR------------------SAQEQPMARAAGTAVPEAE
MAB_1089|M.abscessus_ATCC_1997 EDATALPAGEATL-------------------SDELEDLEEAPSAHTGAE
*: . :
Mflv_1900|M.gilvum_PYR-GCK IRAAAQRED--RDTSEDTG---VYSVIDDEYEDASDD--EYEDE------
Mvan_4830|M.vanbaalenii_PYR-1 E-AVAEGAE--RDTAEDTG---VYSVIDDEYENVEDEYEDAEGE------
TH_3622|M.thermoresistible__bu AEVQAEGDDPVDDVADDVAEDIAEDVVDDIAEDVADEAVDSRDDSHEGED
MSMEG_5468|M.smegmatis_MC2_155 ADEAVEEPEPVAEVAEEPEEADEPAAPVDEDDTADDQSDLAAHE------
Rv0996|M.tuberculosis_H37Rv ADPEADPV-------------------------------EYEYE------
Mb1023|M.bovis_AF2122/97 ADPEADPV-------------------------------EYEYE------
MLBr_00185|M.leprae_Br4923 EEAEAEQR-------------------------------QSD-R------
MAV_1105|M.avium_104 TEAVAKGG-------------------------------DEQDS------
MMAR_4518|M.marinum_M LDGEEEPVDEPQLADEPELADDSELDTAELFAARAANHEHAEDD------
MUL_4690|M.ulcerans_Agy99 LDGEEEPVDESQLGDEPELADDSELDTAELFAARAANHEHAEDD------
MAB_1089|M.abscessus_ATCC_1997 TDSGT---------------------------------------------
Mflv_1900|M.gilvum_PYR-GCK ---------------NQDSDESARGEER------ADTDQRVAGSLSESRR
Mvan_4830|M.vanbaalenii_PYR-1 ---------------YEDVDDASEQGDS------SEADLRMAESISDARR
TH_3622|M.thermoresistible__bu GSQEDEAAADQRGGEYEYVDDSSGLEAP------ADPDSVAADPVTPPRR
MSMEG_5468|M.smegmatis_MC2_155 ---------------YEYVADSSGLEEPETE-PETAEDEAPAAAMSSSRQ
Rv0996|M.tuberculosis_H37Rv ---------------YEYVEDTCGLEL-----EEDDQEAPPTVASGTSRR
Mb1023|M.bovis_AF2122/97 ---------------YEYVEDTCGLEL-----EEDDQEAPPTVASGTSRR
MLBr_00185|M.leprae_Br4923 ---------------YGYVDASSGLGL-----EQKDDKSPVPVAPTVSRQ
MAV_1105|M.avium_104 ---------------YEYVDDSSGLEEPAAEGDEADEEAPAPMPRNASRR
MMAR_4518|M.marinum_M ---------------YEYMDDTSGLAAQAD--DEEGYEPTPRYTSGASRR
MUL_4690|M.ulcerans_Agy99 ---------------YEYMDDTSGLEAQAD--GEEGYEPTPRYTSGASRR
MAB_1089|M.abscessus_ATCC_1997 ---------------YEYVDDTSGLAIAAE---PSRERHQAPPVYSSSRR
:. .*:
Mflv_1900|M.gilvum_PYR-GCK RRRESTTAAAVSARKYRFRARTIAVMSVLMLASAVAALTWSSTMWYSTAA
Mvan_4830|M.vanbaalenii_PYR-1 RRRESTTAAAVSARKYRFRARTIAVMAVLLLASAVAAFTWSPSMWYICGA
TH_3622|M.thermoresistible__bu RRYESKTAAAVAARKYRFRQRMVTTLATAMLVSALVAFFLTPTAWWVCGA
MSMEG_5468|M.smegmatis_MC2_155 RRMESKTAAQVSERKYRFRKRVLALFALILVASAAAAFLVTPTAWWVCGT
Rv0996|M.tuberculosis_H37Rv RRFDTKTAAAVSARKYTFRKRALIVMAVILVGSAAAAFELTPVAWWICGS
Mb1023|M.bovis_AF2122/97 RRFDTKTAAAVSARKYTFRKRALIVMAVILVGSAAAAFELTPVAWWICGS
MLBr_00185|M.leprae_Br4923 RRYDTKTATAVSARKYAFRKRVLMVMAIILVGSAAAAFEVDSNAWWICGS
MAV_1105|M.avium_104 RRFDTKTAAAVSARKYAFRKRVLMAMAVVLVGSATAAFKISPTAWWVCGA
MMAR_4518|M.marinum_M RRYDTKTAAAVSARKYAFRKRMLVAMAVVLVGSAIAAFEVTAAAWWLCSA
MUL_4690|M.ulcerans_Agy99 RRYDTKTAAAVSARKYAFRKRMLVAMAVVLVGSAIAAFEVTAAAWWLCSA
MAB_1089|M.abscessus_ATCC_1997 RRFDPEVMAKENARKFAFRKRVLMGLVGAMVVAGLLAATATSTAWWVCGG
** :. . : **: ** * : : :: :. * . *: .
Mflv_1900|M.gilvum_PYR-GCK VAAVTLLYLAYLRRQTRIEEQVRRRRAQRMARSR-LGVENTSDRDYDVTP
Mvan_4830|M.vanbaalenii_PYR-1 VGTVTALYLAYLRRQTRIEEQVRRRRAQRMARSR-LGVENTSDRDFDVTP
TH_3622|M.thermoresistible__bu FGSAVFLYLAYLRRQTRIEEDLRRRRAQRQARSR-LGVANTRDRDYEVVP
MSMEG_5468|M.smegmatis_MC2_155 TATLTVLYLAYLRRQTRIEEQLRRRRAQRLRRSR-LGVENTDDRKLDVVP
Rv0996|M.tuberculosis_H37Rv ATGVTVLYLAYLRRQTRIEEKVRRRRMQRIARAR-LGVENTRDREYDVVP
Mb1023|M.bovis_AF2122/97 ATGVTVLYLAYLRRQTRIEEKVRRRRMQRIARAR-LGVQNTRDREYDVVP
MLBr_00185|M.leprae_Br4923 STTVTVLYLAYLRRQTRIEEKVRSRRMHRIARAR-VDVENAHDREFDVVP
MAV_1105|M.avium_104 ATTVTLLYLGYLRRQTRIEEKVRRRRMQRMARAR-LGVENAYDRDYDVVP
MMAR_4518|M.marinum_M ATVVTMLYLAYLRRQTRIEAKVRRRRMQRQARAR-LGVENTHDRDYDVVP
MUL_4690|M.ulcerans_Agy99 ATVVTMLYLAYLRRQTRIEAKVRRRRMQRQARAR-LGVENTHDRDYDVVP
MAB_1089|M.abscessus_ATCC_1997 FGVLSVLYLGYLRRQTRIEEQLRRRRAARYQRARVVGVENVADRELDVVP
***.********* .:* ** * *:* :.* *. **. :*.*
Mflv_1900|M.gilvum_PYR-GCK SRLRRPGAAVLEIDDEDPEFEHLDYVPFSRHY----DLPRAAGQ
Mvan_4830|M.vanbaalenii_PYR-1 SRLRRPGAAVLEIDDEDPAFEHLDYVPFSRHY----DLPRAAGQ
TH_3622|M.thermoresistible__bu ARLRRPGAAVLDIDDEDPIFEHLDYAPVADPY----DLPRAAGQ
MSMEG_5468|M.smegmatis_MC2_155 ARLRRPGAVVLDIDDEDPIFEHLEYTTFAREY----DLPRASGQ
Rv0996|M.tuberculosis_H37Rv SRLRRPGAVVLEIDDEDPIFTHLESAAPIRNYGWPRDLPRAVGQ
Mb1023|M.bovis_AF2122/97 SRLRRPGAVVLEIDDEDPIFTHLESAAPIRNYGWPRDLPRAVGQ
MLBr_00185|M.leprae_Br4923 SRLRRPGAVVLEIDDEDPIFEHLDYEMPIRTFGWPRDLPRAVGQ
MAV_1105|M.avium_104 SRLRRPGAVVLEIDDEDPIFEHLEYAMPMRTFGWPRDLPRAVGE
MMAR_4518|M.marinum_M SRLRRPGAVVLEIDDEDPIFEHLDYAGPVRGYGWPRDLPRAVGQ
MUL_4690|M.ulcerans_Agy99 SRLRRPGAVVLEIDDEDPIFEHLDYAGPVRGYGWPRDLPRAVGQ
MAB_1089|M.abscessus_ATCC_1997 QRLRRPGAAVLEIDDEDPVFEHLDYYDEPRQY----RMPHAVGQ
*******.**:****** * **: : :*:* *: