For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSAKERGDQNAVVDALRSIQPAVFIPASVVIVAMIVVSVVYSSVAENAFVRLNSAITGGVGWWYILVATG FVVFALYCGISRIGTIRLGRDDELPEFSFWAWLAMLFSAGMGIGLVFYGVAEPLSHYLRPPRSRGVPALT DAAANQAMALTVFHWGLHAWAIYVVVGLGMAYMTYRRGRPLSVRWLLEPVVGRGRVEGALGHAVDVIAIV GTLFGVATSLGFGITQIASGLEYLGWIRVDNWWMVGMIAAITATATASVVSGVSKGLKWLSNINMALAAA LALFVLLLGPTLFLLQSWVQNLGGYVQSLPQFMLRTAPFSHDGWLGDWTIFYWGWWISWAPFVGMFIARI SRGRTIREFIGAVLLVPTVIASLWFTIFGDSALLRQRNNGDMLVNGAVDTNTSLFRLLDGLPIGAITSVL AVLVIVFFFVTSSDSGSLVIDILSAGGELDPPKLTRVYWAVLEGVAAAVLLLIGGAGSLTALRTAAIATA LPFSIVMVVACYAMTKAFHFDLAATPRLLHVTVPDVVAAGNRRRHDISATLSGLIAVRDVDSGTYIVHPD TGALTVTAPPDPLDDHVFESDRHVTRRNTTSSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0917 | betP | - | 100% (593) | POSSIBLE GLYCINE BETAINE TRANSPORT INTEGRAL MEMBRANE PROTEIN BETP |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0941 | betP | 0.0 | 100.00% (593) | glycine betaine transport integral membrane protein BetP |
| M. gilvum PYR-GCK | Mflv_4702 | - | 1e-123 | 46.18% (498) | choline/carnitine/betaine transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2913 | betP | 0.0 | 86.05% (588) | glycine betaine transport integral membrane protein BetP |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1883 | - | 1e-124 | 46.40% (500) | glycine betaine transporter OpuD |
| M. thermoresistible (build 8) | TH_0652 | - | 1e-123 | 42.75% (552) | glycine betaine transporter OpuD |
| M. ulcerans Agy99 | MUL_2191 | betP | 0.0 | 86.93% (574) | glycine betaine transport integral membrane protein BetP |
| M. vanbaalenii PYR-1 | Mvan_1765 | - | 1e-126 | 45.27% (528) | choline/carnitine/betaine transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4702|M.gilvum_PYR-GCK ------MAGISEHEARAHADTSARSG--TSTEEPALHPVLDRPLDEDRIT
Mvan_1765|M.vanbaalenii_PYR-1 ------MADISAHEPTVIP--AVDTD--DPTIEPTPHPVLDIAVEEERIA
MSMEG_1883|M.smegmatis_MC2_155 MTDEIRKAKFDADEKSVTKTEKVLKSPVGSDVVVPQHPVLDVPVEQKAYT
TH_0652|M.thermoresistible__bu -------MTMTDDTAAAGPRKPRIKS---AAGNVVPHPALDIAPRSQAFA
Rv0917|M.tuberculosis_H37Rv ------------------------------------MSAKERGDQNAVVD
Mb0941|M.bovis_AF2122/97 ------------------------------------MSAKERGDQNAVVD
MMAR_2913|M.marinum_M -------------------------------MALPDLPDSDSGRPNVVAE
MUL_2191|M.ulcerans_Agy99 -------------------------------MALPDLPDSDPGRPNVVAE
. : .
Mflv_4702|M.gilvum_PYR-GCK RSRGIDWVVFGVTAVFAVGFLVWGFLSTESLATASGSALTWVMNNTGWLF
Mvan_1765|M.vanbaalenii_PYR-1 RARGVDWVVFGATAAIAIAFLVWGFRSTDTLASTSSAALAWVMDNTGWLF
MSMEG_1883|M.smegmatis_MC2_155 RREGLDRVVFGVTALIAIGFLVWGFLSTDSLASASADALAWVMNSTGWLF
TH_0652|M.thermoresistible__bu R-RGLDRVVFGVTAALALAFLVWGFVDTDSLAGAADPALGWVMDNIGWLF
Rv0917|M.tuberculosis_H37Rv ALRSIQPAVFIPASVVIVAMIVVSVVYSSVAENAFVRLNSAITGGVGWWY
Mb0941|M.bovis_AF2122/97 ALRSIQPAVFIPASVVIVAMIVVSVVYSSVAENAFVRLNSAITGGVGWWY
MMAR_2913|M.marinum_M AWRSIKPSVFIPASLVIVTMIVVSVVYAQTAANAFVKLNAAITAGVGWWY
MUL_2191|M.ulcerans_Agy99 AWRSIKPPVFVPASLVIVTMIVVSVVYAQTAANAFVKLNAAITAGVGWWY
..:. ** :: . : ::* .. :. : : . ** :
Mflv_4702|M.gilvum_PYR-GCK VLTSTGFVVFVLYLALGRYGAIPLGRDDETPEFNGVSWVAMMFSAGMGIG
Mvan_1765|M.vanbaalenii_PYR-1 VLTSTGFVVFVLYLALGRYGTIPLGRDDESPEFNGISWVAMMFSAGMGIG
MSMEG_1883|M.smegmatis_MC2_155 VLTASGFVVFVVWLAVSRYGNIPLGRDDEEPEFRTVSWVAMMFSAGMGIG
TH_0652|M.thermoresistible__bu VLSASGFVVFVLWLALSRFGNIPLGRDEEEPEFRTISWISMMFAAGMGIG
Rv0917|M.tuberculosis_H37Rv ILVATGFVVFALYCGISRIGTIRLGRDDELPEFSFWAWLAMLFSAGMGIG
Mb0941|M.bovis_AF2122/97 ILVATGFVVFALYCGISRIGTIRLGRDDELPEFSFWAWLAMLFSAGMGIG
MMAR_2913|M.marinum_M ILVATAFVVFALYCGISQIGTIRLGSDDEVPEYGFWAWLAMLFSAGMGIG
MUL_2191|M.ulcerans_Agy99 ILVATAFVVFALYCGISQIGTIRLGSDDEVPEYGFWAWLAMLFSAGMGIG
:* ::.****.:: .:.: * * ** *:* **: :*::*:*:******
Mflv_4702|M.gilvum_PYR-GCK LMFFGVAEPLSHFTTPPPGTGAEGGSEAVQN-AMATTLFHWTLHPWAIYA
Mvan_1765|M.vanbaalenii_PYR-1 LMFFGVAEPLSHFTTPPPGTGAEGNPDAVQN-AMATTLFHWTLHPWAIYA
MSMEG_1883|M.smegmatis_MC2_155 LMFFGVSEPLSHFVTPPPGTGDPGDPAAAQT-AMATTLFHWTLHPWAIYA
TH_0652|M.thermoresistible__bu LMFFGVSEPLTHFVTPPPGAGPGGTSQAVQT-AMATTLFHWTLHPWAIYA
Rv0917|M.tuberculosis_H37Rv LVFYGVAEPLSHYLRPPRSRGVPALTDAAANQAMALTVFHWGLHAWAIYV
Mb0941|M.bovis_AF2122/97 LVFYGVAEPLSHYLRPPRSRGVPALTDAAANQAMALTVFHWGLHAWAIYV
MMAR_2913|M.marinum_M LVFYGVAEPLSHYAHPPQSRGVPALTDAAANQAMALTLFHWGLHAWAIYV
MUL_2191|M.ulcerans_Agy99 LVFYGVAEPLSHYAHPPQSRGVPALTDAAANQAMALPLFHWGLHAWAIYV
*:*:**:***:*: ** . * . . *. . *** .:*** **.****.
Mflv_4702|M.gilvum_PYR-GCK VVGLAIAYGVYRKGRLQLISSAFEPLLG-SRANGSWGKVIDMLAIFATLF
Mvan_1765|M.vanbaalenii_PYR-1 VVGLAIAYGVYRKGRLQLISSAFEPLIG-SRVNGPWGKVIDMLAIFATLF
MSMEG_1883|M.smegmatis_MC2_155 VVGLAIAYGVYRKGRLQLVSAAFEPLLG-ERANGPAGKVIDMLAIFATLF
TH_0652|M.thermoresistible__bu VVGLAIGYGVYRKGRLHLISAAFSPLIG-KNANGPAGKVIDILAIFATLF
Rv0917|M.tuberculosis_H37Rv VVGLGMAYMTYRRGRPLSVRWLLEPVVGRGRVEGALGHAVDVIAIVGTLF
Mb0941|M.bovis_AF2122/97 VVGLGMAYMTYRRGRPLSVRWLLEPVVGRGRVEGALGHAVDVIAIVGTLF
MMAR_2913|M.marinum_M VVGLGMAYMTYRRGRPLSVRWLLEPVLGRRRVEGVLGHAVDVVAIVGTLF
MUL_2191|M.ulcerans_Agy99 VVGLGMAYMTYRRGRPLSVRWLLEPVLGRRRVEGVLGHAVDVVAIVGTLF
****.:.* .**:** : :.*::* ..:* *:.:*::**..***
Mflv_4702|M.gilvum_PYR-GCK GSAASLGLGALQIRSGLQIVAGIGETGNAILVVIISVLTVCFVLSAVSGV
Mvan_1765|M.vanbaalenii_PYR-1 GSAASLGLGALQIRSGLQIVGGVGETGNAILVVIITVLTVCFVLSAVSGV
MSMEG_1883|M.smegmatis_MC2_155 GSAASLGLGALQIRSGLQIVSGIGQVGNTILVVIITVLTVAFVLSAVSGV
TH_0652|M.thermoresistible__bu GSATSLGLGALQIRSGLEIVGGLGRTGNAVLIGIIVILTCAFVISAVSGV
Rv0917|M.tuberculosis_H37Rv GVATSLGFGITQIASGLEYLGWI-RVDNWWMVGMIAAITATATASVVSGV
Mb0941|M.bovis_AF2122/97 GVATSLGFGITQIASGLEYLGWI-RVDNWWMVGMIAAITATATASVVSGV
MMAR_2913|M.marinum_M GVATSLGFGITQIASGLEYLGWI-KTNNWWIIAMIGAITAAATASVVSGV
MUL_2191|M.ulcerans_Agy99 GVATSLGFGITQIASGLEYLGWI-KTNNWWIIAMIGAITAAATASVVSGV
* *:***:* ** ***: :. : ...* :: :* :* . *.****
Mflv_4702|M.gilvum_PYR-GCK ARGIQWLSNINMVLAISLAFFVFVVGPTVFILNLLPTALGSYFADLNMMS
Mvan_1765|M.vanbaalenii_PYR-1 ARGIQWLSNINMVLAVMLALFVFVVGPTVFILNLLPTTMGSYFADLSMMS
MSMEG_1883|M.smegmatis_MC2_155 ARGIQWLSNINMVLAFVLALFIFLVGPTVFMLNMIPTSIGSYVEQLAMMS
TH_0652|M.thermoresistible__bu TRGIQWLSNINMVLAISLAAFIFVVGPTVFMLNLVPTSIGSYLSDLAMMS
Rv0917|M.tuberculosis_H37Rv SKGLKWLSNINMALAAALALFVLLLGPTLFLLQSWVQNLGGYVQSLPQFM
Mb0941|M.bovis_AF2122/97 SKGLKWLSNINMALAAALALFVLLLGPTLFLLQSWVQNLGGYVQSLPQFM
MMAR_2913|M.marinum_M SKGLKWLSNINMALAALLALFVLLLGPTLFLLQSWVQNLGGYAQSLPQFM
MUL_2191|M.ulcerans_Agy99 SKGLKWLSNINMALAALLALFVLLLGPTLFLLQSWVQNLGGYAQSLPQFM
::*::*******.** ** *::::***:*:*: :*.* .* :
Mflv_4702|M.gilvum_PYR-GCK ARTAAEGSDVNEWLQSWTIFYWAWWVSWTPFVGMFIARISRGRTIRQFVG
Mvan_1765|M.vanbaalenii_PYR-1 ARTGAEGADVNVWLQSWTIFYWAWWVSWTPFVGMFIARISRGRTIRQFVA
MSMEG_1883|M.smegmatis_MC2_155 ARTGAEGADVNEWLQSWTIFYWAWWISWTPFVGMFIARISRGRTIRQFIA
TH_0652|M.thermoresistible__bu ARTGAEGAAVNAWLEDWTIFYWAWWISWTPFVGMFIARISRGRTIRQFVS
Rv0917|M.tuberculosis_H37Rv LRTAPFSHDG--WLGDWTIFYWGWWISWAPFVGMFIARISRGRTIREFIG
Mb0941|M.bovis_AF2122/97 LRTAPFSHDG--WLGDWTIFYWGWWISWAPFVGMFIARISRGRTIREFIG
MMAR_2913|M.marinum_M LRTAPFSHDS--WLGNWTIFYWGWWISWAPFVGMFIARISRGRTIREFIG
MUL_2191|M.ulcerans_Agy99 LRTAPFSHDS--WLGNWTIFYWGWWISWAPFVGMFIARISRGRTIREFIG
**.. . ** .******.**:**:*****************:*:.
Mflv_4702|M.gilvum_PYR-GCK GVLLVPSLVSLVWFAVFGGAAINVQQSGTDLAGEGG--VEAQLFSLLDQY
Mvan_1765|M.vanbaalenii_PYR-1 GVLLVPSLVSLIWFAVFGGSAINLQQNGTDLAGEGG--VEEQLFTLLDRY
MSMEG_1883|M.smegmatis_MC2_155 GVLFVPSVVSLVWFCVFGGAAIHEQQNGVDLAGEGS--VEQQLFGLLDQY
TH_0652|M.thermoresistible__bu GVLVVPSVVSLVWFCVLGGSAIRVEQESGGLTGPGTT-IEGQLFGLLENL
Rv0917|M.tuberculosis_H37Rv AVLLVPTVIASLWFTIFGDSALLRQRNNGDMLVNGAVDTNTSLFRLLDGL
Mb0941|M.bovis_AF2122/97 AVLLVPTVIASLWFTIFGDSALLRQRNNGDMLVNGAVDTNTSLFRLLDGL
MMAR_2913|M.marinum_M AVLLVPTVIASLWFTIFGDAALLRQRNDGDMLVNGAVDTNTSLFRLLGDL
MUL_2191|M.ulcerans_Agy99 AVLLVPTVIASLWFTIFGDAALLRQRNDGDMLVNGAVDTNTSLFRLLGDL
.**.**:::: :** ::*.:*: ::.. .: * : .** **
Mflv_4702|M.gilvum_PYR-GCK PIATIASVVVMVLVAIFFVSGADAASVVMGSLSQKGTIHPSRGTVVFWGV
Mvan_1765|M.vanbaalenii_PYR-1 PIATVTSVIVIVLVAIFFVSGADAASVVMGSLSQQGTIKPSRGIVVFWGT
MSMEG_1883|M.smegmatis_MC2_155 PIATIASILVMLLVAIFFVSGADAASIVMGSLSERGTIKPTRPTVIFWGV
TH_0652|M.thermoresistible__bu PLTAIASVLVMGLVAIFFVTGADSASIVMGSLSERGTIEPTKRTVIFWGV
Rv0917|M.tuberculosis_H37Rv PIGAITSVLAVLVIVFFFVTSSDSGSLVIDILSAGGELDPPKLTRVYWAV
Mb0941|M.bovis_AF2122/97 PIGAITSVLAVLVIVFFFVTSSDSGSLVIDILSAGGELDPPKLTRVYWAV
MMAR_2913|M.marinum_M PIGVITSVLAVVVIVFFFITSSDSGSLVIDILSAGGELDPPKLTRVYWAV
MUL_2191|M.ulcerans_Agy99 PIGVITSVLAVLVIVFFFITSSDSGSLVIDILSAGGELDPPKLTRVYWAV
*: .::*::.: ::.:**::.:*:.*:*:. ** * :.*.: ::*..
Mflv_4702|M.gilvum_PYR-GCK ATGAVAAVMLLVGGEDALTGLQTITIIAALPFVLVMIGLAVSLVKDLRTD
Mvan_1765|M.vanbaalenii_PYR-1 ATGAVAAVMLLVGGADALTGLQTITIVAALPFVLVMVGLAVALVKDLRRD
MSMEG_1883|M.smegmatis_MC2_155 ATGAVAAVMLLVGGEDALNGLQTITIIAALPFVVVMVGLTVSLMRDLRRD
TH_0652|M.thermoresistible__bu ATGAVAAVMLLLGGEDALTGLQTIVILASVPFVLVMLGLAVALMRDLRRD
Rv0917|M.tuberculosis_H37Rv LEGVAAAVLLLIGGAGSLTALRTAAIATALPFSIVMVVACYAMTKAFHFD
Mb0941|M.bovis_AF2122/97 LEGVAAAVLLLIGGAGSLTALRTAAIATALPFSIVMVVACYAMTKAFHFD
MMAR_2913|M.marinum_M LEGTAAAILLLVGGSGSLTALQTASIATALPFSIVMVVACYAMLKAFRFD
MUL_2191|M.ulcerans_Agy99 LEGTAAAILLLVGGSGSLTALQTASIATALPFSIVMVVACYAMLKAFRFD
*..**::**:** .:*..*:* * :::** :**: :: : :: *
Mflv_4702|M.gilvum_PYR-GCK ------------PMVV----RRKYANEAVESAVISG-------VTQHGDD
Mvan_1765|M.vanbaalenii_PYR-1 ------------PKVV----RRQYAAEAVNSAVIAG-------VTRHGDD
MSMEG_1883|M.smegmatis_MC2_155 ------------PMIV----RREYAVEAVNSAVVQG-------VTQHGDD
TH_0652|M.thermoresistible__bu ------------PMMV----RRRYAREAVDDAVIAG-------VTQHGDD
Rv0917|M.tuberculosis_H37Rv LAATPRLLHVTVPDVVAAGNRRRHDISATLSGLIAVRDVDSGTYIVHPDT
Mb0941|M.bovis_AF2122/97 LAATPRLLHVTVPDVVAAGNRRRHDISATLSGLIAVRDVDSGTYIVHPDT
MMAR_2913|M.marinum_M LLTTPRLLHVTVPDVVSDNGRQRRDISATLAGLIAVRDVDSGTYSVHPDT
MUL_2191|M.ulcerans_Agy99 LLTTPRLLHVTVPDVVSDGNRQRRDISATLAGLIAVRDVDSGTCSVHPDT
* :* *:. .*. .:: * *
Mflv_4702|M.gilvum_PYR-GCK FIISVEKDPHCDGGKPGG--------------------------------
Mvan_1765|M.vanbaalenii_PYR-1 FVIAVEKHSR----------------------------------------
MSMEG_1883|M.smegmatis_MC2_155 FVIAVEKDPNADNGHDDRADADSAEVADEPGAETSDKTKDVPAGG-----
TH_0652|M.thermoresistible__bu FVIAVKRDPAATGAGVTGTDGDSG--------------------------
Rv0917|M.tuberculosis_H37Rv GALTVTAPPDPLDDHVFESDRHVTR------------RNTTSSR------
Mb0941|M.bovis_AF2122/97 GALTVTAPPDPLDDHVFESDRHVTR------------RNTTSSR------
MMAR_2913|M.marinum_M GALTVTTPPDPLGGHMFDTSEQDGQ------------RNTTSSA------
MUL_2191|M.ulcerans_Agy99 GALTVITPPDPLGGHMFDTSEQDGQPPLAVAPASYWFTGVTTSQQSIPDY
::* .
Mflv_4702|M.gilvum_PYR-GCK -----------------------------
Mvan_1765|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_1883|M.smegmatis_MC2_155 -----------------------------
TH_0652|M.thermoresistible__bu -----------------------------
Rv0917|M.tuberculosis_H37Rv -----------------------------
Mb0941|M.bovis_AF2122/97 -----------------------------
MMAR_2913|M.marinum_M -----------------------------
MUL_2191|M.ulcerans_Agy99 SRSNRSLFMTLAHAAAKSSANFCLASLWA