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M. tuberculosis H37Rv Rv0733 (adk)

annotation: adenylate kinase
coordinates: 826122 - 826667
length: 181

VRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTKLGVEAKRYLDAGDLVPSDLTNELVDD
RLNNPDAANGFILDGYPRSVEQAKALHEMLERRGTDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNR
MKVYRDETAPLLEYYRDQLKTVDAVGTMDEVFARALRALGK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0733adk-100% (181)adenylate kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0754adk2e-99100.00% (181) adenylate kinase
M. gilvum PYR-GCKMflv_5021adk1e-7374.59% (181) adenylate kinase
M. leprae Br4923MLBr_01832adk6e-8683.98% (181) adenylate kinase
M. abscessus ATCC 19977MAB_3783c-6e-7170.72% (181) adenylate kinase
M. marinum MMMAR_1071adk8e-8785.64% (181) adenylate kinase (ATP-AMP transphosphorylase), Adk
M. avium 104MAV_4433adk7e-8987.85% (181) adenylate kinase
M. smegmatis MC2 155MSMEG_1484adk6e-7878.45% (181) adenylate kinase
M. thermoresistible (build 8)TH_0326adk1e-7777.90% (181) PROBABLE ADENYLATE KINASE ADK (ATP-AMP TRANSPHOSPHORYLASE)
M. ulcerans Agy99MUL_0829adk4e-8786.19% (181) adenylate kinase
M. vanbaalenii PYR-1Mvan_1348adk3e-7677.35% (181) adenylate kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5021|M.gilvum_PYR-GCK          MREGPKLRIVLLGPPGAGKGTQAQKLAEKLAIPHISTGDLFRYNISNNTE
Mvan_1348|M.vanbaalenii_PYR-1       ------MRIVLLGPPGAGKGTQAQKLAEKLGIPQISTGDLFRYNISNGTE
Rv0733|M.tuberculosis_H37Rv         ------MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTK
Mb0754|M.bovis_AF2122/97            ------MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTK
MLBr_01832|M.leprae_Br4923          ------MRVVLLGPPGAGKGTQAQRLAEKLGIPQISTGELFRRNIEKDTK
MMAR_1071|M.marinum_M               ------MRVVLLGPPGAGKGTQAQKLAEKLGIPQISTGELFRKNIQDGTK
MUL_0829|M.ulcerans_Agy99           ------MRVVLLGPPGAGKGTQAQKLAEKLGIPQISTGELFRKNIQDGTK
MAV_4433|M.avium_104                ------MRVVLLGPPGAGKGTQAQKLSEKLGIPQISTGELFRSNIENGTK
MSMEG_1484|M.smegmatis_MC2_155      ------MRVVLLGPPGAGKGTQAEKLSEKLGIPQISTGDLFRKNIGDGTP
TH_0326|M.thermoresistible__bu      ------VRIVLLGAPGAGKGTQAQKLSEKLGIPQISTGDLFRQNISEGTE
MAB_3783c|M.abscessus_ATCC_199      ------MRVVLLGPPGAGKGTQAQLISEKFGIPQISTGDLFRSNISEGTE
                                          :*::***.*********  ::**:.**:****:*** ** ..* 

Mflv_5021|M.gilvum_PYR-GCK          LGIEAKKYLDAGDLVPATLTNALVDDRLDDEDAAQGFILDGFPRSVEQAK
Mvan_1348|M.vanbaalenii_PYR-1       LGLEAKKYLDAGDLVPATLTNALVDDRLDDEDAAAGFILDGYPRSVEQAK
Rv0733|M.tuberculosis_H37Rv         LGVEAKRYLDAGDLVPSDLTNELVDDRLNNPDAANGFILDGYPRSVEQAK
Mb0754|M.bovis_AF2122/97            LGVEAKRYLDAGDLVPSDLTNELVDDRLNNPDAANGFILDGYPRSVEQAK
MLBr_01832|M.leprae_Br4923          LGHEAKKYLDAGDLVPADLTNQLVDDRLNKSDTVDGFILDGYPRSLEQAK
MMAR_1071|M.marinum_M               LGIEAKRYLDAGDLVPSDLTNQLVDDRLDQPDTAAGFILDGYPRSVEQAK
MUL_0829|M.ulcerans_Agy99           LGVEAKRYLDAGDLVPSDLTNQLVDDRLDQPDTAAGFILDGYPRSVEQAK
MAV_4433|M.avium_104                LGLEAKRYLDAGDLVPAELTNQLVDDRLSEPDAANGFILDGFPRSLQQAK
MSMEG_1484|M.smegmatis_MC2_155      LGLEAKRYLDAGDLVPAELTNRLVEDRIDQPDAAEGFILDGYPRSVEQAG
TH_0326|M.thermoresistible__bu      LGLEAKRYLDAGDLVPASLTNALVEDRINQPDAANGFILDGFPRSVEQAE
MAB_3783c|M.abscessus_ATCC_199      LGLQAKQYLDAGDLVPSEVTNKMVEARLDEPDAAAGFILDGFPRTVDQAD
                                    ** :**:*********: :** :*: *:.. *:. ******:**:::** 

Mflv_5021|M.gilvum_PYR-GCK          ALAEMLEKRGLTLDAVVEFRVPEEELVSRLKGRGREDDTEDVIRNRFKVY
Mvan_1348|M.vanbaalenii_PYR-1       ALDEMLKKRDLSLDAVLEFRVPEEELVSRLKGRGRDDDTEDVIRNRFRVY
Rv0733|M.tuberculosis_H37Rv         ALHEMLERRGTDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNRMKVY
Mb0754|M.bovis_AF2122/97            ALHEMLERRGTDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNRMKVY
MLBr_01832|M.leprae_Br4923          ALHEMLERRGTDIDAVLEFRVSQAVVLERLKGRGRADDTDDVVINRMNIY
MMAR_1071|M.marinum_M               ALHEMLRRRDTDIDAVLEFRVSQDELLQRLKGRGRADDTDEVILNRMKVY
MUL_0829|M.ulcerans_Agy99           ALHEMLRRRDTDIDAVLEFRVSQDELLQRLKGRGRADDTDEVILNRMKVY
MAV_4433|M.avium_104                ALHEMLERRGTDIDAVLEFRVSQDELLARLKARGRADDTDEVILNRMKVY
MSMEG_1484|M.smegmatis_MC2_155      ALKDMLAARNTKLDAVLEFQVSEDELLTRLKGRGRADDTDEVIRNRMKVY
TH_0326|M.thermoresistible__bu      ALDEMLKKLNVRLDAVLEFQVSEEELLARLKARGRADDTEDVIRNRMAVY
MAB_3783c|M.abscessus_ATCC_199      ALAAMEEARGVTIDAVLEFRVPVEELVQRLLGRGRADDTEDIIRNRLNVY
                                    **  *    .  :***:**:*.   :: ** .*** ***:::: **: :*

Mflv_5021|M.gilvum_PYR-GCK          RDETAPLLDFYSADLKTVDAVGELDEVFDRALTALGR
Mvan_1348|M.vanbaalenii_PYR-1       RDETAPLLDYYSADLKTVDAVGELDEVFARALKALGR
Rv0733|M.tuberculosis_H37Rv         RDETAPLLEYYRDQLKTVDAVGTMDEVFARALRALGK
Mb0754|M.bovis_AF2122/97            RDETAPLLEYYRDQLKTVDAVGTMDEVFARALRALGK
MLBr_01832|M.leprae_Br4923          RDETASLLEYYSSELKTIDAIGTMDEVFARALHALGK
MMAR_1071|M.marinum_M               RDETAPLLEFYDTEVKTVDAIGTLDEVFARALQALGK
MUL_0829|M.ulcerans_Agy99           RDETAPLLEFYDTEVKTVDAIGTLDEVFARALQALGK
MAV_4433|M.avium_104                RDETAPLLDYYRDQLKTVDAVGTLDEVFARALRALGK
MSMEG_1484|M.smegmatis_MC2_155      REETEPLLEYYRDDLKTVNAVGALDEVFARALSALGQ
TH_0326|M.thermoresistible__bu      RSETEPLLDYYRDQLKTVDAVGTLDEVFERALTALGR
MAB_3783c|M.abscessus_ATCC_199      RDETAPLLEYYQNVLQTIDAVGTVDEVFARTSQALGR
                                    *.** .**::*   ::*::*:* :**** *:  ***: