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M. tuberculosis H37Rv Rv0669c (-)

annotation: POSSIBLE HYDROLASE
coordinates: 767684 - 769597
length: 637

LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPLPMQNVNE
EVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVA
PAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTNR
NHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGL
CQFEDAFTQLSGATPIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFR
QGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIV
AGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAM
RDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEV
VRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATT
REFTVV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0669c--100% (637)POSSIBLE HYDROLASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0688c-0.099.84% (637) hydrolase
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0997-0.081.60% (636) ceramidase
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv0669c|M.tuberculosis_H37Rv      MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQD
Mb0688c|M.bovis_AF2122/97         MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQD
MMAR_0997|M.marinum_M             MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHLRLRSRAFVFRDDSQD
                                  ********************************** ***************

Rv0669c|M.tuberculosis_H37Rv      GDARLLLIVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAG
Mb0688c|M.bovis_AF2122/97         GDARLLLIVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAG
MMAR_0997|M.marinum_M             ENPRLLLVVAELPMPMQNVNDEVLRRLAESYGDTYTEQNTLITTTHTHAG
                                   :.****:*****:******:*******: *****:*******:******

Rv0669c|M.tuberculosis_H37Rv      PGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVSLSHG
Mb0688c|M.bovis_AF2122/97         PGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVPLSHG
MMAR_0997|M.marinum_M             PGGYCGYLMYNLTTNGFRPATFAAIVDGIVESVTHAHDDVAPAEVMLSHG
                                  ********:*****.****************** *** ******* ****

Rv0669c|M.tuberculosis_H37Rv      ELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHF
Mb0688c|M.bovis_AF2122/97         ELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHF
MMAR_0997|M.marinum_M             ELHSASINRSPSAFDRNPEADKAFFPNRIDPQTTLVRIDRGEHTVGAIHF
                                  **:.************** *******:*:**:********** ***.***

Rv0669c|M.tuberculosis_H37Rv      FATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQT
Mb0688c|M.bovis_AF2122/97         FATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQT
MMAR_0997|M.marinum_M             FATHGTSMTNRNRMISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQT
                                  ************::************************************

Rv0669c|M.tuberculosis_H37Rv      NPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG
Mb0688c|M.bovis_AF2122/97         NPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG
MMAR_0997|M.marinum_M             NPGDMSPNVDGPLPPGAAPQCALENTRQIGLRQFEDASTQLGATTSIGTG
                                  *************.* *.*:  ::***: ** ***** ***..:*.**:*

Rv0669c|M.tuberculosis_H37Rv      IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGF
Mb0688c|M.bovis_AF2122/97         IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGF
MMAR_0997|M.marinum_M             IDARLTYVDLSSVRVRGEFTPDGQEHRTGSPTVGAGGMAGTEEGKGFQGF
                                  ****:*****.** ****:****:*:*** * .***.****:** **:**

Rv0669c|M.tuberculosis_H37Rv      RQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVP
Mb0688c|M.bovis_AF2122/97         RQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVP
MMAR_0997|M.marinum_M             HQGQNLFWDKLSGAMFRLAGALGATQAPKGIVVPAGLPNRVHPFVQEIAP
                                  :**:* ***:** **:*** . .*:*******:** ****:*******.*

Rv0669c|M.tuberculosis_H37Rv      VQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAY
Mb0688c|M.bovis_AF2122/97         VQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAY
MMAR_0997|M.marinum_M             VQLVRIGRLYLIGIPGEPTVVAGLRLRRTVASIVGAELADVLCVGYCNAY
                                  *******************:******** *******:********* ***

Rv0669c|M.tuberculosis_H37Rv      IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLG
Mb0688c|M.bovis_AF2122/97         IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLG
MMAR_0997|M.marinum_M             IHYLTTPEEYLEQRYEGGSTLFGRWELPAFMQIVAGLAEAMRDGRPIAPG
                                  ***:*********************** *:** ** **********:: *

Rv0669c|M.tuberculosis_H37Rv      RRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNN
Mb0688c|M.bovis_AF2122/97         RRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNN
MMAR_0997|M.marinum_M             PRPRLARPLSWGRAAPADTGSFGAVIAEPAASYRPGEAVQAAFVSALPSN
                                   *** :* *** *.****:**********:*:****:**:*.******.*

Rv0669c|M.tuberculosis_H37Rv      DLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV
Mb0688c|M.bovis_AF2122/97         DLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV
MMAR_0997|M.marinum_M             DLRRGDTYLEVQRREGQDWARVADDGDWSTSFHWERQGRAGSRVSIRWEI
                                  *****.***** **** .*.*:******:***:*:*******:*****::

Rv0669c|M.tuberculosis_H37Rv      PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV
Mb0688c|M.bovis_AF2122/97         PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV
MMAR_0997|M.marinum_M             PCDTAPGQYRIVHHGAARNGVGALTPFTATTREFTVG
                                  * **:**********:**:  * **.*:********