For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0584 (-)

annotation: POSSIBLE CONSERVED EXPORTED PROTEIN
coordinates: 679229 - 681862
length: 877

MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVP
FGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVG
VPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATS
GGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDG
ARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDG
VIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDS
VVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGAS
VTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQ
DGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIG
QPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTG
KSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGA
GSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAI
TVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv0584 - - 100% (877) POSSIBLE CONSERVED EXPORTED PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0599 - 0.0 99.89% (877) hypothetical protein Mb0599
M. gilvum PYR-GCK - - - - -
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_0952 - 0.0 71.51% (874) alpha-1,2-mannosidase
M. avium 104 MAV_4560 - 0.0 71.53% (871) alpha-1,2-mannosidase family protein
M. smegmatis MC2 155 - - - - -
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 - - - - -
M. vanbaalenii PYR-1 - - - - -

CLUSTAL 2.0.9 multiple sequence alignment


Rv0584|M.tuberculosis_H37Rv      MRARRLRRALAALLAVAGLFVPFIVGVP-TAYDGEPVFVAIPVEHVNTLI
Mb0599|M.bovis_AF2122/97         MRARRLRRALAALLAVAGLFVPFIVGVP-TAYDGEPVFVAIPVEHVNTLI
MMAR_0952|M.marinum_M            MRSPRLLRGLAALLAVLGLLLPLLAAAPPRAYDGEPSLVANPVDYVDTLV
MAV_4560|M.avium_104             MRSR---TAPIALVATLAVLMTVIAPAPPRGYDGPPLFVANPVDHVVTLI
                                 **:     .  **:*. .:::..:. .*  .*** * :** **::* **:

Rv0584|M.tuberculosis_H37Rv      GTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSM
Mb0599|M.bovis_AF2122/97         GTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYGNPHSTGFSM
MMAR_0952|M.marinum_M            GTGTGGEIVGEINNFPGAAVPFGMVQYSPDTTDNYAGYDYQNPRSTGFSM
MAV_4560|M.avium_104             GTGTGGETVGEINNFPGATVPFGMVQYSPDTAGNYAGYNYDNPRATGFSM
                                 *****.  **********:************..*****:* **::*****

Rv0584|M.tuberculosis_H37Rv      THASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRF
Mb0599|M.bovis_AF2122/97         THASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRF
MMAR_0952|M.marinum_M            THASVGCAAFGDISVLPTTTAISVQPWRGAERIAHDDSEVGVPGYYSVRF
MAV_4560|M.avium_104             THASVGCAAFGDISMLPVTGGLGVQPWNATERIAHDDTERGVPGYYTVRL
                                 *******.******:**.*  :. *** . *.*****:* ******:**:

Rv0584|M.tuberculosis_H37Rv      PGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQI-
Mb0599|M.bovis_AF2122/97         PGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQI-
MMAR_0952|M.marinum_M            PATGVTAELTATTRTGFGRFSYPRDGRPALLRVQSGASLAGNSRSTIQLG
MAV_4560|M.avium_104             PGAGVTAELTATAHTGVGRFSYPGDGRPALLQVRSGSSLAGNSRATIQLG
                                 *.:** ******::**.*** ** :* ***::*:**:*****  :*:*: 

Rv0584|M.tuberculosis_H37Rv      EDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSH
Mb0599|M.bovis_AF2122/97         EDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSH
MMAR_0952|M.marinum_M            ADNTTITGWATSGGFCGKNNTYTVYFAMKFNQPFISYGAWDGYAVYAGVR
MAV_4560|M.avium_104             EDNTTITGWATSGGFCDKPNAYTVYFAMKFNRPFISYGSWDGSTVYPGAR
                                  ******* *******.* * *********.:** ***:*** :**.* :

Rv0584|M.tuberculosis_H37Rv      SMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRA
Mb0599|M.bovis_AF2122/97         SMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRA
MMAR_0952|M.marinum_M            GAHSRRSGAYVEFPSGAALEVQTAISYVGIDGARANLAAEGAASFDDVRT
MAV_4560|M.avium_104             SANAPYSGGYVEFPAGSVLEVRTAISYVGIEGARANLAAEGNAGFDDVRA
                                 . ::  **.** **:*:.***:**:***.::****** *** *.***:*:

Rv0584|M.tuberculosis_H37Rv      ATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGF
Mb0599|M.bovis_AF2122/97         ATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGF
MMAR_0952|M.marinum_M            AAAREWNAALLRIAVAGRDPDELVTFYSCLYRSLLHPNTFNDADGRYLGF
MAV_4560|M.avium_104             AAARQWNAALSRVTVAGRNSDDLTTFYTALYRTLLHPNMFNDADGRYVGF
                                 *:: :***** *::****...:: ***:.***:***** ***.****:**

Rv0584|M.tuberculosis_H37Rv      DGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAE
Mb0599|M.bovis_AF2122/97         DGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAE
MMAR_0952|M.marinum_M            DGAIHTVPQGHTQYANFSDWDTYRSLAALQGLLFPSQASDMAQSLVNDAE
MAV_4560|M.avium_104             DGGIHRVADGHVQYANFSDWDTYRCLAALQALLFPDRAADMAQSLVTDAQ
                                 ** ** *..**.:***********.**.**.****.:*:** ****.**:

Rv0584|M.tuberculosis_H37Rv      QSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNA
Mb0599|M.bovis_AF2122/97         QSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNA
MMAR_0952|M.marinum_M            QSGAFPRWPLANSSTGMMTGDNAVPLIVNLYTFGAKDFDVHTALRYMVNA
MAV_4560|M.avium_104             QSGALPRWAFANAATGEMSGDSVVPLIVNLNTFGANDFDTAAALRYMVDG
                                 **** ***.:**::** *:**..******* :***.***  :**:***:.

Rv0584|M.tuberculosis_H37Rv      ATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVD
Mb0599|M.bovis_AF2122/97         ATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVD
MMAR_0952|M.marinum_M            ATRGGVGLNGYVERPGITTYQELGFGPQVSEFATGGRIAGASITLEWAID
MAV_4560|M.avium_104             ATKGGVGLAGYVERRGIATYLRLGYAPFTLEFGRNGWIADASITLEWSID
                                 **:***** *::** **::* .**:.* . **  .* **.**:****::*

Rv0584|M.tuberculosis_H37Rv      DFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDG
Mb0599|M.bovis_AF2122/97         DFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDG
MMAR_0952|M.marinum_M            DFTISRFAQALGDDKTAAEFQHRSQYWQNLFNPSTGFISPRDRMGFFPDG
MAV_4560|M.avium_104             DFAISRFADSLGDAATAAEFANRAQYWQNLFNPSTRSVVPRSWSGFFRPG
                                 **:*****::***  *** * :*:*********:*  : **.  ***  *

Rv0584|M.tuberculosis_H37Rv      PGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDR
Mb0599|M.bovis_AF2122/97         PGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDR
MMAR_0952|M.marinum_M            PGFTEIPEGFGQDGFDEGNAEQYLWMVPQNIAGLVTALGGRAAAENRLDR
MAV_4560|M.avium_104             PAVVVSPANFGQVGYDEGNAEQYVWSVPHNVAGLVTALGGRAAVADRLDR
                                 *...  * .*** *:********:* **:*:**********:*. .****

Rv0584|M.tuberculosis_H37Rv      FTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGP
Mb0599|M.bovis_AF2122/97         FTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGP
MMAR_0952|M.marinum_M            FTKKLNVGPNQPYLWAGNEPGFGVPWIYNYLGAPWKTQRTVNRVRGLFAA
MAV_4560|M.avium_104             FTKKLNVGPNQPYLWAGNEPSFGVPWLYNYIGQPWKTQHTVDRVRGLFGP
                                 **********:*********.*****:***:* *****:**:******..

Rv0584|M.tuberculosis_H37Rv      TPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALP
Mb0599|M.bovis_AF2122/97         TPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALP
MMAR_0952|M.marinum_M            TPDGAPGNDDLGALSSWYVWAALGLYPITAGTPILTVNTPLFDRAVISLP
MAV_4560|M.avium_104             TADGEPGNDDLGALAGWYVWAALGLYPATPGTPILTVAAPLFDRIEIALP
                                 *..* *********:.*********** *.**.**** :*****  *:**

Rv0584|M.tuberculosis_H37Rv      TGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFS
Mb0599|M.bovis_AF2122/97         TGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFS
MMAR_0952|M.marinum_M            ADKFIRLSAPGASAPSHMRYISGLRINGAATDQTYLPESIITTGGDVAFE
MAV_4560|M.avium_104             AGKSIRIAAPGASGPHHPAYISGLKVDGRPTGHTWLPESIIRTGGTLAFS
                                 :.* *:::*****.  :  **.** ::  .:.:*:*****: *** ::*.

Rv0584|M.tuberculosis_H37Rv      LAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDA
Mb0599|M.bovis_AF2122/97         LAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDA
MMAR_0952|M.marinum_M            LAAVPNKQWGSGPSSAPPSFGAGGSAVTVNVPRPIIRIAPGTTRTVRVDL
MAV_4560|M.avium_104             LAAYPDKHWGTAESDAPPSFGAGSSAVAVNVPQPVVSIAPGHRGSVTLDA
                                 **. *:* **:. * ********.***:**:.:*:: *.**   :* :* 

Rv0584|M.tuberculosis_H37Rv      QRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPS
Mb0599|M.bovis_AF2122/97         QRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPS
MMAR_0952|M.marinum_M            QRMITGIDEFTITGESSTGGITVVPTSGRFAENGSATTRVGITVDKSVDN
MAV_4560|M.avium_104             QRMIDGAGGYTVSGAASDAGVAVTPTSGQFDADGAASVSVPITVAPTVPQ
                                 **** * . :*::  :   *::. * **:*  :*:.:. * ***  :* .

Rv0584|M.tuberculosis_H37Rv      GYYPIYVTTSAGDSARTLIVLVVVAEAVE--
Mb0599|M.bovis_AF2122/97         GYYPIYVTTSAGDSARTLIVLVVVAEAVE--
MMAR_0952|M.marinum_M            EYYLTYLTTTAGATSRTSTVLVVVLGYDE--
MAV_4560|M.avium_104             DYYLVSLTTTVGQSTRTTTVLVDTQAEPESR
                                  **   :**:.* ::**  *** .    *

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv0584	-	-	100% (877)	POSSIBLE CONSERVED EXPORTED PROTEIN