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M. tuberculosis H37Rv Rv0519c (-)

annotation: POSSIBLE CONSERVED MEMBRANE PROTEIN
coordinates: 611172 - 612074
length: 300

LRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAGAAGVWAFGALVDPLEPQAAPAPFEPPTAGSSLPT
RISGSFISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGLARLVKEGKPAFAVVG
VDGGNTYWHRRSSGGDSGAMVLDELLPMLTSMGMDTSRVGFLGWSMGGYGALLLGARLGPARTAGICAIS
PALFTSFTGSTPGAFDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAGSFSPGG
HDASYWREQLPGELAWMAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0519c--100% (300)POSSIBLE CONSERVED MEMBRANE PROTEIN
M. tuberculosis H37RvRv0774c-2e-9457.05% (298) hypothetical protein Rv0774c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0532c-1e-178100.00% (300) hypothetical protein Mb0532c
M. gilvum PYR-GCKMflv_1609-7e-8656.58% (281) putative esterase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0684c-1e-8555.87% (281) hypothetical protein MAB_0684c
M. marinum MMMAR_0858-1e-14484.01% (294) hypothetical protein MMAR_0858
M. avium 104MAV_4629-1e-12175.64% (275) putative esterase superfamily protein
M. smegmatis MC2 155MSMEG_5851-1e-10363.27% (294) putative esterase superfamily protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0610-1e-14483.67% (294) hypothetical protein MUL_0610
M. vanbaalenii PYR-1Mvan_5149-4e-8756.84% (285) putative esterase

CLUSTAL 2.0.9 multiple sequence alignment


Rv0519c|M.tuberculosis_H37Rv        ---------MLRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAG----
Mb0532c|M.bovis_AF2122/97           ---------MLRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAG----
MMAR_0858|M.marinum_M               MSRDNYVARLSGVPRPETRCRHGIMALVADLTRRAVLRMGAGTSAG----
MUL_0610|M.ulcerans_Agy99           ------------MPRPETRCRHGIMALVADLTRRAVLRMGAGTSAG----
MAV_4629|M.avium_104                --------------------------------------MGAGASLG----
Mflv_1609|M.gilvum_PYR-GCK          ---------------------------MPMINRRDVLSLGLRAAM-----
Mvan_5149|M.vanbaalenii_PYR-1       -----------------------MMSRMPTLNRREMLALGLRAGL-----
MAB_0684c|M.abscessus_ATCC_199      ---------------------------MRDLSRRSLLKLG----------
MSMEG_5851|M.smegmatis_MC2_155      ------------------------MAGMPTLSRRAVLRLGVGAAAGAAGA
                                                                           *          

Rv0519c|M.tuberculosis_H37Rv        ------AAGVWAFGALVDPLEPQAAP-----APFEPPTAGSSLPTRISGS
Mb0532c|M.bovis_AF2122/97           ------AAGVWAFGALVDPLEPQAAP-----APFEPPTAGSSLPTRISGS
MMAR_0858|M.marinum_M               ------AAGMWALSAWLNPLEPKAAPP-QAPAPFEPPAAGSSLPTRLSGS
MUL_0610|M.ulcerans_Agy99           ------AAGMWALSAWLNPLEPKAAPP-QAPAPFEPPAAGSSLPTRLSGS
MAV_4629|M.avium_104                ------AAGVFALSALLDPGTARAATLPQAPAPFEPPTAGKTLPTRLTGS
Mflv_1609|M.gilvum_PYR-GCK          -----VATAGTAAASLLDTPASAAP----------------PAPTYTTGS
Mvan_5149|M.vanbaalenii_PYR-1       -----AATA----ASALGTAVASAA----------------PAPTFVTGS
MAB_0684c|M.abscessus_ATCC_199      -----AATG--AGAALLGAGAFPAG----------------ADGAIAAGS
MSMEG_5851|M.smegmatis_MC2_155      VAFGVAATATPGQPAPQTPPAPQAPPV-----PLEPPAT--AAPTYVTGS
                                          *:.     :   .    *                 .  :  :**

Rv0519c|M.tuberculosis_H37Rv        FISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGL
Mb0532c|M.bovis_AF2122/97           FISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGL
MMAR_0858|M.marinum_M               FISAARGGIKTNWVIALPPGQTGLLRPVIALHGKDGNAGMMLDLGVEEGL
MUL_0610|M.ulcerans_Agy99           FISAARGGIKTNWVIALPPGQTGLLRPVIALHGKDGNAGMMLDLGVEEGL
MAV_4629|M.avium_104                FVSAARGGIKTNYVIAIPPGQTGMLRPVIALHGVDGDANQMLDMGVPDGL
Mflv_1609|M.gilvum_PYR-GCK          FPSAARGGAVTNWAIARPPGRTEPLRPVILLHGKDSSAATVMSMGVEQFL
Mvan_5149|M.vanbaalenii_PYR-1       FASAARGGAVTNWVIARPPDQTAPLRPVILLHGKDSSAEMVMSMGVERFL
MAB_0684c|M.abscessus_ATCC_199      FVSAARGGVRTEWRIARPPGVTGPIRPIIALHGKGQTAAGVMEGGVENML
MSMEG_5851|M.smegmatis_MC2_155      FVSAARGGVATNWAIARPPGQTAPLRPVIALHGKGQDAAGVMAGGVEQGL
                                    * ******  *:: *: **. :  :**:* *** .  *  ::  **   *

Rv0519c|M.tuberculosis_H37Rv        ARLVKEGKPAFAVVGVDGGNT-YWHRRSSGGDSGAMVLDELLPMLTSMGM
Mb0532c|M.bovis_AF2122/97           ARLVKEGKPAFAVVGVDGGNT-YWHRRSSGGDSGAMVLDELLPMLTSMGM
MMAR_0858|M.marinum_M               AQLVKSGKPPFAVVGVDGGKTSYWHRRASGGDSGAMVLEELLPMLAAMGM
MUL_0610|M.ulcerans_Agy99           AQLVKSGKPPFAVVGVDGGKTSYWHRRASGGDSGAMVLEELLPMLAAMGM
MAV_4629|M.avium_104                AQLVKAGKPPFAVVGVDGGNT-YWHKRTSGEDSGAMVLDELLPMLSTMGF
Mflv_1609|M.gilvum_PYR-GCK          ADAVRAGLPPFAMAAVDGGNG-YWHRRASGDDAGAMVLDEFLPLLAAQGL
Mvan_5149|M.vanbaalenii_PYR-1       ADAVRAGLPPFAMAAVDGGNG-YWHRRASGDDPGAMVLDEFLPLLATQGL
MAB_0684c|M.abscessus_ATCC_199      AQAVAAGAKPFALASVDGGGG-YWHKRASGEDSGAMVLNEFIPLLAEQGL
MSMEG_5851|M.smegmatis_MC2_155      AEAVAAGLPPFAVVAVDGGGS-YWHKRASGEDSGAMVLDELIPMLGEQGL
                                    *  *  *  .**:..****   ***:*:** *.*****:*::*:*   *:

Rv0519c|M.tuberculosis_H37Rv        DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFTSFTGSTPGA
Mb0532c|M.bovis_AF2122/97           DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFTSFTGSTPGA
MMAR_0858|M.marinum_M               DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFSSFTGSAPGA
MUL_0610|M.ulcerans_Agy99           DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFSSFTGSAPGA
MAV_4629|M.avium_104                DTSRVGFMGWSMGGYGALRLGAKLGPSRTAGICAISPALYTSYATSAPGA
Mflv_1609|M.gilvum_PYR-GCK          DTSRVGFLGWSMGGYGALLLGSRLGAGRTAAICAVSPALWTSPGAAAPGA
Mvan_5149|M.vanbaalenii_PYR-1       DTSRVAFLGWSMGGYGAMLLGSRLGAGRTAAITAVSPALWTSPGAAAPGA
MAB_0684c|M.abscessus_ATCC_199      DTSRVAFLGWSMGGYGAMLLGSRLGAGRTAAITAVSPALWTSSGAAAPGA
MSMEG_5851|M.smegmatis_MC2_155      DTSRVGFLGWSMGGYGALLLGSRLGPARTAAICAVSPALWTSPGAAAPGA
                                    *****.*:*********: **::**..***.* *:****::*   ::***

Rv0519c|M.tuberculosis_H37Rv        FDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAG
Mb0532c|M.bovis_AF2122/97           FDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAG
MMAR_0858|M.marinum_M               FDSYDDWMAHRVVGLPALNQIPLRVDCGTSDRFYFATRQFVNQLKNPPAG
MUL_0610|M.ulcerans_Agy99           FDSYDDWMAHRVVGLPALNQIPLRVDCGTSDRFYFATRQFVNHLKNPPAG
MAV_4629|M.avium_104                FDSNEDFVQNSVLGLPALNSIPLRVDCGNFDRFYFATKQFVYQLKTPPAG
Mflv_1609|M.gilvum_PYR-GCK          FDGAEDYAAHSVWGPAGLDGIPLRIDCGYDDPFASATEQFIAQLPSPPAG
Mvan_5149|M.vanbaalenii_PYR-1       FDGAADYEANSVWGLAALNGIPLRIDCGFDDPFYSATEQFIAQLSTPPAG
MAB_0684c|M.abscessus_ATCC_199      FDGAEDYAANSVWGLAALNSIPLRIDCGDSDPFYSATKQFIAQLPTPPAG
MSMEG_5851|M.smegmatis_MC2_155      FDNAEDYNANSVWGQPALASIPLRIDCGTSDPFYAATRQFIAQLPNAPAG
                                    **.  *:  : * * ..*  ****:***  * *  **.**: :*  .***

Rv0519c|M.tuberculosis_H37Rv        SFSPGGHDASYWREQLPGELAWMAS----
Mb0532c|M.bovis_AF2122/97           SFSPGGHDASYWREQLPGELAWMAS----
MMAR_0858|M.marinum_M               SFSPGGHDAEYWREHLPGELAWMAS----
MUL_0610|M.ulcerans_Agy99           SFSPGGHDAEYWREHLPGELAWMAS----
MAV_4629|M.avium_104                SFSLGGHDIAFWRSQLPAELAWMAT----
Mflv_1609|M.gilvum_PYR-GCK          GFSPGGHNAQFWSGQLTSEMTWMAPLLAA
Mvan_5149|M.vanbaalenii_PYR-1       GFSPGGHNAAFWSSQLTSEMTWAAPLLAT
MAB_0684c|M.abscessus_ATCC_199      GFSPGGHDGAFWSSQIGAEMAWMAPLLTA
MSMEG_5851|M.smegmatis_MC2_155      GFSPGGHNGEFWSAQLPGELTWMAPLLVA
                                    .** ***:  :*  :: .*::* *.