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LRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAGAAGVWAFGALVDPLEPQAAPAPFEPPTAGSSLPT RISGSFISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGLARLVKEGKPAFAVVG VDGGNTYWHRRSSGGDSGAMVLDELLPMLTSMGMDTSRVGFLGWSMGGYGALLLGARLGPARTAGICAIS PALFTSFTGSTPGAFDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAGSFSPGG HDASYWREQLPGELAWMAS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0519c | - | - | 100% (300) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv0774c | - | 2e-94 | 57.05% (298) | hypothetical protein Rv0774c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0532c | - | 1e-178 | 100.00% (300) | hypothetical protein Mb0532c |
M. gilvum PYR-GCK | Mflv_1609 | - | 7e-86 | 56.58% (281) | putative esterase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0684c | - | 1e-85 | 55.87% (281) | hypothetical protein MAB_0684c |
M. marinum M | MMAR_0858 | - | 1e-144 | 84.01% (294) | hypothetical protein MMAR_0858 |
M. avium 104 | MAV_4629 | - | 1e-121 | 75.64% (275) | putative esterase superfamily protein |
M. smegmatis MC2 155 | MSMEG_5851 | - | 1e-103 | 63.27% (294) | putative esterase superfamily protein |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0610 | - | 1e-144 | 83.67% (294) | hypothetical protein MUL_0610 |
M. vanbaalenii PYR-1 | Mvan_5149 | - | 4e-87 | 56.84% (285) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment Rv0519c|M.tuberculosis_H37Rv ---------MLRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAG---- Mb0532c|M.bovis_AF2122/97 ---------MLRRGCAGNTDRRGIMTPMADLTRRALLRWGAGAGAG---- MMAR_0858|M.marinum_M MSRDNYVARLSGVPRPETRCRHGIMALVADLTRRAVLRMGAGTSAG---- MUL_0610|M.ulcerans_Agy99 ------------MPRPETRCRHGIMALVADLTRRAVLRMGAGTSAG---- MAV_4629|M.avium_104 --------------------------------------MGAGASLG---- Mflv_1609|M.gilvum_PYR-GCK ---------------------------MPMINRRDVLSLGLRAAM----- Mvan_5149|M.vanbaalenii_PYR-1 -----------------------MMSRMPTLNRREMLALGLRAGL----- MAB_0684c|M.abscessus_ATCC_199 ---------------------------MRDLSRRSLLKLG---------- MSMEG_5851|M.smegmatis_MC2_155 ------------------------MAGMPTLSRRAVLRLGVGAAAGAAGA * Rv0519c|M.tuberculosis_H37Rv ------AAGVWAFGALVDPLEPQAAP-----APFEPPTAGSSLPTRISGS Mb0532c|M.bovis_AF2122/97 ------AAGVWAFGALVDPLEPQAAP-----APFEPPTAGSSLPTRISGS MMAR_0858|M.marinum_M ------AAGMWALSAWLNPLEPKAAPP-QAPAPFEPPAAGSSLPTRLSGS MUL_0610|M.ulcerans_Agy99 ------AAGMWALSAWLNPLEPKAAPP-QAPAPFEPPAAGSSLPTRLSGS MAV_4629|M.avium_104 ------AAGVFALSALLDPGTARAATLPQAPAPFEPPTAGKTLPTRLTGS Mflv_1609|M.gilvum_PYR-GCK -----VATAGTAAASLLDTPASAAP----------------PAPTYTTGS Mvan_5149|M.vanbaalenii_PYR-1 -----AATA----ASALGTAVASAA----------------PAPTFVTGS MAB_0684c|M.abscessus_ATCC_199 -----AATG--AGAALLGAGAFPAG----------------ADGAIAAGS MSMEG_5851|M.smegmatis_MC2_155 VAFGVAATATPGQPAPQTPPAPQAPPV-----PLEPPAT--AAPTYVTGS *:. : . * . : :** Rv0519c|M.tuberculosis_H37Rv FISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGL Mb0532c|M.bovis_AF2122/97 FISAARGGIKTNWVISMPPGQSGQLRPVIALHGKDGNAGMMLDLGVEQGL MMAR_0858|M.marinum_M FISAARGGIKTNWVIALPPGQTGLLRPVIALHGKDGNAGMMLDLGVEEGL MUL_0610|M.ulcerans_Agy99 FISAARGGIKTNWVIALPPGQTGLLRPVIALHGKDGNAGMMLDLGVEEGL MAV_4629|M.avium_104 FVSAARGGIKTNYVIAIPPGQTGMLRPVIALHGVDGDANQMLDMGVPDGL Mflv_1609|M.gilvum_PYR-GCK FPSAARGGAVTNWAIARPPGRTEPLRPVILLHGKDSSAATVMSMGVEQFL Mvan_5149|M.vanbaalenii_PYR-1 FASAARGGAVTNWVIARPPDQTAPLRPVILLHGKDSSAEMVMSMGVERFL MAB_0684c|M.abscessus_ATCC_199 FVSAARGGVRTEWRIARPPGVTGPIRPIIALHGKGQTAAGVMEGGVENML MSMEG_5851|M.smegmatis_MC2_155 FVSAARGGVATNWAIARPPGQTAPLRPVIALHGKGQDAAGVMAGGVEQGL * ****** *:: *: **. : :**:* *** . * :: ** * Rv0519c|M.tuberculosis_H37Rv ARLVKEGKPAFAVVGVDGGNT-YWHRRSSGGDSGAMVLDELLPMLTSMGM Mb0532c|M.bovis_AF2122/97 ARLVKEGKPAFAVVGVDGGNT-YWHRRSSGGDSGAMVLDELLPMLTSMGM MMAR_0858|M.marinum_M AQLVKSGKPPFAVVGVDGGKTSYWHRRASGGDSGAMVLEELLPMLAAMGM MUL_0610|M.ulcerans_Agy99 AQLVKSGKPPFAVVGVDGGKTSYWHRRASGGDSGAMVLEELLPMLAAMGM MAV_4629|M.avium_104 AQLVKAGKPPFAVVGVDGGNT-YWHKRTSGEDSGAMVLDELLPMLSTMGF Mflv_1609|M.gilvum_PYR-GCK ADAVRAGLPPFAMAAVDGGNG-YWHRRASGDDAGAMVLDEFLPLLAAQGL Mvan_5149|M.vanbaalenii_PYR-1 ADAVRAGLPPFAMAAVDGGNG-YWHRRASGDDPGAMVLDEFLPLLATQGL MAB_0684c|M.abscessus_ATCC_199 AQAVAAGAKPFALASVDGGGG-YWHKRASGEDSGAMVLNEFIPLLAEQGL MSMEG_5851|M.smegmatis_MC2_155 AEAVAAGLPPFAVVAVDGGGS-YWHKRASGEDSGAMVLDELIPMLGEQGL * * * .**:..**** ***:*:** *.*****:*::*:* *: Rv0519c|M.tuberculosis_H37Rv DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFTSFTGSTPGA Mb0532c|M.bovis_AF2122/97 DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFTSFTGSTPGA MMAR_0858|M.marinum_M DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFSSFTGSAPGA MUL_0610|M.ulcerans_Agy99 DTSRVGFLGWSMGGYGALLLGARLGPARTAGICAISPALFSSFTGSAPGA MAV_4629|M.avium_104 DTSRVGFMGWSMGGYGALRLGAKLGPSRTAGICAISPALYTSYATSAPGA Mflv_1609|M.gilvum_PYR-GCK DTSRVGFLGWSMGGYGALLLGSRLGAGRTAAICAVSPALWTSPGAAAPGA Mvan_5149|M.vanbaalenii_PYR-1 DTSRVAFLGWSMGGYGAMLLGSRLGAGRTAAITAVSPALWTSPGAAAPGA MAB_0684c|M.abscessus_ATCC_199 DTSRVAFLGWSMGGYGAMLLGSRLGAGRTAAITAVSPALWTSSGAAAPGA MSMEG_5851|M.smegmatis_MC2_155 DTSRVGFLGWSMGGYGALLLGSRLGPARTAAICAVSPALWTSPGAAAPGA *****.*:*********: **::**..***.* *:****::* ::*** Rv0519c|M.tuberculosis_H37Rv FDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAG Mb0532c|M.bovis_AF2122/97 FDSYDDYVQHSVLGLPALNSIPLRVDCGTSDRFYFATRQFVNQLHQPPAG MMAR_0858|M.marinum_M FDSYDDWMAHRVVGLPALNQIPLRVDCGTSDRFYFATRQFVNQLKNPPAG MUL_0610|M.ulcerans_Agy99 FDSYDDWMAHRVVGLPALNQIPLRVDCGTSDRFYFATRQFVNHLKNPPAG MAV_4629|M.avium_104 FDSNEDFVQNSVLGLPALNSIPLRVDCGNFDRFYFATKQFVYQLKTPPAG Mflv_1609|M.gilvum_PYR-GCK FDGAEDYAAHSVWGPAGLDGIPLRIDCGYDDPFASATEQFIAQLPSPPAG Mvan_5149|M.vanbaalenii_PYR-1 FDGAADYEANSVWGLAALNGIPLRIDCGFDDPFYSATEQFIAQLSTPPAG MAB_0684c|M.abscessus_ATCC_199 FDGAEDYAANSVWGLAALNSIPLRIDCGDSDPFYSATKQFIAQLPTPPAG MSMEG_5851|M.smegmatis_MC2_155 FDNAEDYNANSVWGQPALASIPLRIDCGTSDPFYAATRQFIAQLPNAPAG **. *: : * * ..* ****:*** * * **.**: :* .*** Rv0519c|M.tuberculosis_H37Rv SFSPGGHDASYWREQLPGELAWMAS---- Mb0532c|M.bovis_AF2122/97 SFSPGGHDASYWREQLPGELAWMAS---- MMAR_0858|M.marinum_M SFSPGGHDAEYWREHLPGELAWMAS---- MUL_0610|M.ulcerans_Agy99 SFSPGGHDAEYWREHLPGELAWMAS---- MAV_4629|M.avium_104 SFSLGGHDIAFWRSQLPAELAWMAT---- Mflv_1609|M.gilvum_PYR-GCK GFSPGGHNAQFWSGQLTSEMTWMAPLLAA Mvan_5149|M.vanbaalenii_PYR-1 GFSPGGHNAAFWSSQLTSEMTWAAPLLAT MAB_0684c|M.abscessus_ATCC_199 GFSPGGHDGAFWSSQIGAEMAWMAPLLTA MSMEG_5851|M.smegmatis_MC2_155 GFSPGGHNGEFWSAQLPGELTWMAPLLVA .** ***: :* :: .*::* *.