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M. tuberculosis H37Rv Rv0493c (-)

annotation: hypothetical protein Rv0493c
coordinates: 583701 - 584690
length: 329

GESTTQPAGGAAVDDETRSAALPRWRGAAGRLEVWYATLSDPLTRTGLWVHCETVAPTTGGPYAHGWVTW
FPPDAPPGTERFGPQPAQPAAGPAWFDIAGVRMAPAELTGRTRSLAWELSWKDTAAPLWTFPRVAWEREL
LPGAQVVIAPTAVFAGSLAVGETTHRVDSWRGSVAHIYGHGNAKRWGWIHADLGDGDVLEVVTAVSHKPG
LRRLAPLAFVRFRIDGKDWPASPLPSLRMRTTLGVRHWQLEGRIGGREALIRVDQPPERCVSLGYTDPDG
AKAVCTNTEQADIHIELGGRHWSVLGTGHAEVGLRGTAAPAIKEGTPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0493c--100% (329)hypothetical protein Rv0493c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0504c-0.099.70% (329) hypothetical protein Mb0504c
M. gilvum PYR-GCKMflv_2092-7e-1325.66% (265) hypothetical protein Mflv_2092
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0819-1e-14976.95% (321) hypothetical protein MMAR_0819
M. avium 104MAV_4658-1e-14173.42% (316) hypothetical protein MAV_4658
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4612-3e-1024.72% (271) hypothetical protein Mvan_4612

CLUSTAL 2.0.9 multiple sequence alignment


Rv0493c|M.tuberculosis_H37Rv       MGESTTQPAGGAAVDDETRSAALPRWRGAAGRLEVWYATLSDPLTRTGLW
Mb0504c|M.bovis_AF2122/97          MGESTTQPAGGAAVDDETRSAALPRWRGAAGRLEVWYATLSDPLTRTGLW
MMAR_0819|M.marinum_M              -------------MDEEMRSAVAPRWQGKPGRLEVWYATLSDPSTQAGLW
MAV_4658|M.avium_104               -------------MDDEKRSAAAPRWRGRPGRLEVWYATLSDPRTGAGLW
Mflv_2092|M.gilvum_PYR-GCK         ------------MDAGAVTIAQAPYYESR-------FIRANAPNADRALW
Mvan_4612|M.vanbaalenii_PYR-1      -------------------MAKAPYYESR-------FIRANDPDTARAVW
                                                       *  * :..        :   . * :  .:*

Rv0493c|M.tuberculosis_H37Rv       VHCETVAPTTG-GPYAHGWVTWFPPDAPPGTERFGPQPAQPAAGPAWFD-
Mb0504c|M.bovis_AF2122/97          VHCETVAPTTG-GPYAHGWVTWFPPDAPPGTERFGPQPAQPAAGPAWFD-
MMAR_0819|M.marinum_M              VHYETVAPTTGDAPYAHGWATWFPPDGPPRTGRFGPAPVGPATGAAWFE-
MAV_4658|M.avium_104               VHCETVAPLRG-AAYGHGWATWFPPDGPPRTGRFGPVPAHPATGPDWFA-
Mflv_2092|M.gilvum_PYR-GCK         VRETLLLTTTG-ATSADVWVMVFDPSGHHAVKQQYPIDDAVFDRDPWTAR
Mvan_4612|M.vanbaalenii_PYR-1      LRETLLLPTVG-EPVADVWVMVFDPSGHRAVKQQFTIAEAAFGYDDWTAR
                                   ::   : .  *  . .. *.  * *..   . :  .          *   

Rv0493c|M.tuberculosis_H37Rv       IAGVRMAPAELTGRTRSLAWELSWKDT-AAPLWTFPRVAWERELLPGAQV
Mb0504c|M.bovis_AF2122/97          IAGVRMAPAELTGRTRSLAWELSWKDT-AAPLWTFPRVAWERELLPGAQV
MMAR_0819|M.marinum_M              AAGARAAHESLTGRAGSLSWDLSWKDA-AAPLWTFPRVAWERELLPGAQV
MAV_4658|M.avium_104               CAGVRVADEQLRGRAGALAWELSWTDP-TRPLWTFPRLAWERELLPGAQV
Mflv_2092|M.gilvum_PYR-GCK         IANTSLDDTAAAGALPTATWELSISPGGHDPVRVLADHAYQRRFPPAKTM
Mvan_4612|M.vanbaalenii_PYR-1      IASTVLDDTAAFGALADARWDLAITASGQEPVRVLSDRAYQARFPTAKTS
                                    *..        *      *:*: .     *: .:.  *:: .: ..   

Rv0493c|M.tuberculosis_H37Rv       VIAPTAVFAGSLAVGETTHRVDSWRGSVAHIYG--HGNAKRWGWIHADLG
Mb0504c|M.bovis_AF2122/97          VIAPTAVFAGSLAVGETTHRVDSWRGGVAHIYG--HGNAKRWGWIHADLG
MMAR_0819|M.marinum_M              VLAPTAEFSGSLTVGDTSHPIGGWRGGVAHIYG--HGNAKRWGWIHADLG
MAV_4658|M.avium_104               VLAPTAEFTGRLHLDGASARVEGWRGGVAHIYG--HGNARRWGWMHADLG
Mflv_2092|M.gilvum_PYR-GCK         VRHPLARFDGRLEIADRVLDVDDWTGSVNHNWGTRHTPAYAYGQVCGFDD
Mvan_4612|M.vanbaalenii_PYR-1      VRDPLARFDGHLEISGHGVDIDGWTGSVNHNWGTRHTPAYAYGQVCGFDN
                                   *  * * * * * :      : .* *.* * :*  *  *  :* : .  .

Rv0493c|M.tuberculosis_H37Rv       DGDVLEVVTAVSHKPGLRRLAPLAFVRFRIDGKDWPASPLP-SLRMRTTL
Mb0504c|M.bovis_AF2122/97          DGDVLEVVTAVSHKPGLRRLAPLAFVRFRIDGKDWPASPLP-SLRMRTTL
MMAR_0819|M.marinum_M              HGDVLEVVTAVSHKPGLRRLAPMAFVRFRIDGKDWPASPLP-SLRMRTTL
MAV_4658|M.avium_104               GGDVLEVVSAVSHRPGLRRLAPLAFVRFRLDGNDWPASVLP-SLRMRTRL
Mflv_2092|M.gilvum_PYR-GCK         APDSTLEIITARTALGPVALPGATLFVFRHAGQEFAVRSIRGSLQTHGRY
Mvan_4612|M.vanbaalenii_PYR-1      APEATLEIVTARAALGPVLLPGVTLFVFRHEGQQFAVRSIRGSLQSHGRY
                                     :    : :.    *   *.  ::. **  *:::..  :  **: :   

Rv0493c|M.tuberculosis_H37Rv       GVRHWQLEGRIGGREALIRVDQPPERCVSLGYTDPDGAKAVCTNTEQADI
Mb0504c|M.bovis_AF2122/97          GVRHWQLEGRIGGREALIRVDQPPERCVSLGYTDPDGAKAVCTNTEQADI
MMAR_0819|M.marinum_M              GIAHWQLEGRIDGRDVLIRVDQPAERCVSLQYTDPDGGKAVCTNTERADV
MAV_4658|M.avium_104               QLPHWQLAGRIGGRRVCIRADLPPERCVSLGYTDPDGGTAVCTNTERADI
Mflv_2092|M.gilvum_PYR-GCK         APFRWTFGARVGEQMIQGEITTEPADVIGLTYADTHGGVKYCYNSSLAHC
Mvan_4612|M.vanbaalenii_PYR-1      APFRWTFGARVGEQMIEGEITTVPSDVIGLTYSDTHGGVKYCYNSAIANC
                                      :* : .*:. :    .    .   :.* *:*..*.   * *:  *. 

Rv0493c|M.tuberculosis_H37Rv       HIELGG-----RHWSVLGTGHAEVGLRGT---AAPAIKEGTPA
Mb0504c|M.bovis_AF2122/97          HIELGG-----RHWSVLGTGHAEVGLRGT---AAPAIKEGTPA
MMAR_0819|M.marinum_M              HVEISRNRVIERSWSVLGTGHAEVGLRDTRDAKAPAVNERR--
MAV_4658|M.avium_104               RVEIDD-----RRWSVLG--HAEVGLRGA---EAPAVNERIPA
Mflv_2092|M.gilvum_PYR-GCK         RIQVAG--KAFERSELVSRRAMFEILTDAPVDSVPLLV-----
Mvan_4612|M.vanbaalenii_PYR-1      RIQVAG--KAFERSELVSRRAMFEILTDDRLDSVPLLA-----
                                   ::::       .  .::.       * .     .* :