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M. tuberculosis H37Rv Rv0448c (-)

annotation: hypothetical protein Rv0448c
coordinates: 536504 - 537169
length: 221

HHSFAYRSYSWYVDVDNLPQLPWWLRPFARFHADDHFADPFSCPPHSSLRDRLDAFFAARGLAVPDGRIT
ALLQARVLGYVFNPLSIFWCHDRDGQLRHVIAEVHNTYGGRHAYLLPPADLPVVTAKNFYVSPFHQLAGY
YLIRAPRPDRELDVTVTLHRDRRQVCPEFTATLRGQRRPATTRQIAMMQIISPLAPMVVAARIRIQGIRL
WLRRVPVVPR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0448c--100% (221)hypothetical protein Rv0448c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0456c-1e-132100.00% (221) hypothetical protein Mb0456c
M. gilvum PYR-GCKMflv_1819-3e-6756.31% (222) hypothetical protein Mflv_1819
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0769-1e-10276.92% (221) hypothetical protein MMAR_0769
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1403-1e-10075.57% (221) hypothetical protein MUL_1403
M. vanbaalenii PYR-1Mvan_4926-4e-7358.11% (222) hypothetical protein Mvan_4926

CLUSTAL 2.0.9 multiple sequence alignment


Rv0448c|M.tuberculosis_H37Rv       --------------------------------------------------
Mb0456c|M.bovis_AF2122/97          --------------------------------------------------
MMAR_0769|M.marinum_M              -----------------------------MLTQTRVLTPAIYRTTITHAR
MUL_1403|M.ulcerans_Agy99          --------------------------------------------------
Mflv_1819|M.gilvum_PYR-GCK         MNPIRTLDRPIAVAPAPRDLDAQRPARRRRTAPAPRVSTALYRTRITHLR
Mvan_4926|M.vanbaalenii_PYR-1      ------------------------------------MRAAIYRTRITHLR
                                                                                     

Rv0448c|M.tuberculosis_H37Rv       ---MHHSFAYRSYSWYVDVDNLPQLPWWLRPFARFHADDHFADPFSCPPH
Mb0456c|M.bovis_AF2122/97          ---MHHSFAYRSYSWYVDVDNLPQLPWWLRPFARFHADDHFADPFSCPPH
MMAR_0769|M.marinum_M              RVPVHHTFGYRSYSWYVDVDDLPRLPWWLRPMARFHADDHFIS----PPQ
MUL_1403|M.ulcerans_Agy99          ---MHHSFGYRSYSWYVDVDDLPRLPWWLRPMARFQADDHFIS----PPQ
Mflv_1819|M.gilvum_PYR-GCK         RAPVHHYFEQSSYSWFVDLDALPRVPRWLRPFARFQARDHLWD----APV
Mvan_4926|M.vanbaalenii_PYR-1      RAPVHHYFEHRSYSWFVDLDALPRLPRWLRPFAGFEARDHLWE----APR
                                      :** *   ****:**:* **::* ****:* *.* **: .    .* 

Rv0448c|M.tuberculosis_H37Rv       SSLRDRLDAFFAARGLAVPDGRITALLQARVLGYVFNPLSIFWCHDRDGQ
Mb0456c|M.bovis_AF2122/97          SSLRDRLDAFFAARGLAVPDGRITALLQARVLGYVFNPLSIFWCHDRDGQ
MMAR_0769|M.marinum_M              GSLRDRLEAFFAEQGAEIPDGRVTALLQARVFGYVFNPLSVFWCHDRDGR
MUL_1403|M.ulcerans_Agy99          GSLRDRLEAFFAEQGAEIPDGRVTALLQARVFGYVFNPLSVFWCHDRDGR
Mflv_1819|M.gilvum_PYR-GCK         DTLRGRIDAFLAGKGIDLRGGRVTALLQPRVLGQVFNPLTLYWCYDANGV
Mvan_4926|M.vanbaalenii_PYR-1      DTLRGRVDAFLAGKGIDLGGGTVTALMQPRVLGHVFNPLTLYWCHDSNGV
                                   .:**.*::**:* :*  : .* :***:*.**:* *****:::**:* :* 

Rv0448c|M.tuberculosis_H37Rv       LRHVIAEVHNTYGGRHAYLLPP--ADLPVVTAKNFYVSPFHQLAGYYLIR
Mb0456c|M.bovis_AF2122/97          LRHVIAEVHNTYGGRHAYLLPP--ADLPVVTAKNFYVSPFHQLAGYYLIR
MMAR_0769|M.marinum_M              LRHVVAEVHNTYGGRHAYLLPP--AELPVAAAKNFYVSPFNQVDGYYLIQ
MUL_1403|M.ulcerans_Agy99          LRHVVAEVHNTYGGRHAYLLPP--AELPVAAVKNFYVSPFNQVDGYYLIQ
Mflv_1819|M.gilvum_PYR-GCK         LRCVVAEVQNTHGERHAYLMPPTSTDRPAAVDKKLYMSPFTGVDGYYLVR
Mvan_4926|M.vanbaalenii_PYR-1      LRCIIAEAHNTHGDRHAYLLPP-STDPPVMVDKKLYASPFNGVDGHYLVR
                                   ** ::**.:**:* *****:**  :: *. . *::* ***  : *:**::

Rv0448c|M.tuberculosis_H37Rv       APRPDRELDVTVTLHRDRRQVCPEFTATLRGQRRPATTRQIAMMQIISPL
Mb0456c|M.bovis_AF2122/97          APRPDRELDVTVTLHRDRRQVCPEFTATLRGQRRPATTRQIAMMQIISPL
MMAR_0769|M.marinum_M              APRPEAEVDVTVSLHRENRQ---SFTANLHGKRLPATTKQVAIMQIIAPL
MUL_1403|M.ulcerans_Agy99          APRPEAEVNVTVSLHRENRQ---SFTANLHGKRLPATTKQVAIMQITAPL
Mflv_1819|M.gilvum_PYR-GCK         APEPDERLDVTVSLLRDDQP---AFVATLRGTRRPAGARQIMAMQVLSPV
Mvan_4926|M.vanbaalenii_PYR-1      APEPDERLDVTVSLHREQQP---AFVVTLRGSRRPAGIRQVLAMQIVAPL
                                   **.*: .::***:* *: :     *...*:* * **  :*:  **: :*:

Rv0448c|M.tuberculosis_H37Rv       APMVVAARIRIQGIRLWLRRVPVVPR------------------------
Mb0456c|M.bovis_AF2122/97          APMVVAARIRIQGIRLWLRRVPVVPR------------------------
MMAR_0769|M.marinum_M              APLVVAARIRIQGIKLWLRRVPVVPR------------------------
MUL_1403|M.ulcerans_Agy99          APLVVAARIRIQGIKLWLRRVPVVPR------------------------
Mflv_1819|M.gilvum_PYR-GCK         APLMNKMSMRVQGALLRLRRVPTTPHPN----------ARPARDRRKIPS
Mvan_4926|M.vanbaalenii_PYR-1      APLMNALSTRVQGALLWLRRVPVVPRGSDERRAPVETVTRLDAGRRCPAG
                                   **::     *:**  * *****..*:                        

Rv0448c|M.tuberculosis_H37Rv       -------------
Mb0456c|M.bovis_AF2122/97          -------------
MMAR_0769|M.marinum_M              -------------
MUL_1403|M.ulcerans_Agy99          -------------
Mflv_1819|M.gilvum_PYR-GCK         TSLMRCPQ-----
Mvan_4926|M.vanbaalenii_PYR-1      PILTRDPQETRSP