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M. tuberculosis H37Rv Rv0446c (-)

annotation: POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 534445 - 535215
length: 256

VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLS
WHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAV
WLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPL
LMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0446c--100% (256)POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0454c-1e-151100.00% (256) transmembrane protein
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0767-1e-12078.04% (255) transmembrane protein
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1401-1e-11978.04% (255) transmembrane protein
M. vanbaalenii PYR-1Mvan_3685-9e-0626.92% (156) hypothetical protein Mvan_3685

CLUSTAL 2.0.9 multiple sequence alignment


Rv0446c|M.tuberculosis_H37Rv       -------MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAV
Mb0454c|M.bovis_AF2122/97          -------MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAV
MMAR_0767|M.marinum_M              MIGDGILLISGASAAALIVVHSVTFAIGHRIGRYNVVDVAWGLGFVAVAA
MUL_1401|M.ulcerans_Agy99          -------MISGASAAALIVVHSVTFAIGHRIGRYNVVDVAWGLGFVAVAA
Mvan_3685|M.vanbaalenii_PYR-1      ------------MATAALVFYGIFIVLGFGWRSY----------------
                                                * *  *.:.: :.:*     *                

Rv0446c|M.tuberculosis_H37Rv       AAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRG
Mb0454c|M.bovis_AF2122/97          AAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRG
MMAR_0767|M.marinum_M              VSAVLGSGDPTRRWLLLTLVAIWGLRLSWHIHRKTVGKGEDPRYTDLLRD
MUL_1401|M.ulcerans_Agy99          VSAVLGSGDPTRRWLLLALVAIWGLRLSRHIHRKRVGKGEDPRYTDLLRG
Mvan_3685|M.vanbaalenii_PYR-1      -----------RQWRRTGSTGMRGFHGRPGSLEWLAGAG--------FVV
                                              *:*     ..  *::      .  .* *        :  

Rv0446c|M.tuberculosis_H37Rv       ATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWL
Mb0454c|M.bovis_AF2122/97          ATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWL
MMAR_0767|M.marinum_M              ATLGQVVRKVFVLQAFLTLFISFPLQLSAVTGPTPKPLLAVGALGVAVWL
MUL_1401|M.ulcerans_Agy99          ATLGQVVRKVFVLQAFLTLFISFPLQLSAVTGPTPKPLLAVGALGVAVWL
Mvan_3685|M.vanbaalenii_PYR-1      AIVAGALAPILQVAGLLSPVVTLDAPLFAALG----TVAAVVGIAATLWA
                                   *    .:  :: : .:*: .:::   * *. *    .: ** .:. ::* 

Rv0446c|M.tuberculosis_H37Rv       VGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGL
Mb0454c|M.bovis_AF2122/97          VGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGL
MMAR_0767|M.marinum_M              LGVVFEALGDHQLRAFKADPANRGAIMDRGLWAWTRHPNYFGDACVWWGL
MUL_1401|M.ulcerans_Agy99          LGVVFEALGDHQLRAFKADPANRGAIMDRGLWAWTRHPNYFGDACVWWGL
Mvan_3685|M.vanbaalenii_PYR-1      Q----ESMGDS--WRIGVDAGETTRLVEGGMFGWVRNPIFTAMLVFGAGV
                                        *::**     :  *..:   ::: *::.*.*:* : .   .  *:

Rv0446c|M.tuberculosis_H37Rv       WLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRT
Mb0454c|M.bovis_AF2122/97          WLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRT
MMAR_0767|M.marinum_M              WLVTITGWVPLITVGSPLLMTYFLVDVSGARLTEKYMKDRPGFGEYQRRT
MUL_1401|M.ulcerans_Agy99          WLVTITGWVPLITVGSPLLMTYFLVDVSGARLTEKYMKDRPGFGEYQRRT
Mvan_3685|M.vanbaalenii_PYR-1      ALMAPN---PLALIGFVLLLTSIELQVRFVEEPYLHRTHSERYRNYASRV
                                    *:: .   **  :*  **:* : ::*  .. .  : .    : :*  *.

Rv0446c|M.tuberculosis_H37Rv       AYFVPRPPRSARR----
Mb0454c|M.bovis_AF2122/97          AYFVPRPPRSARR----
MMAR_0767|M.marinum_M              AYFVPRPPRSARHQ---
MUL_1401|M.ulcerans_Agy99          AYFVPRPPRSARHQ---
Mvan_3685|M.vanbaalenii_PYR-1      GRFVPRIGRSPAGGPSA
                                   . ****  **.