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IGKPRGRRGVNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMG AEIDSLADAVNFGVTPALVLYVSMLSKWPVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMP APAGAVSMIGLLALKMQFGEGWWTSGWFLSFWVTGTSILLVSGIPMKKMHAVSVPPNYAAALLAVLAICA AAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQHPEVWDDKPKQRRAVRRASRRAHPYRPSMARLGLRK PGRRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0436c | pssA | - | 100% (286) | PROBABLE CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE PSSA (PS SYNTHASE) (PHOSPHATIDYLSERINE SYNTHASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0444c | pssA | 1e-164 | 99.65% (286) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. gilvum PYR-GCK | Mflv_0154 | - | 4e-92 | 60.57% (279) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. leprae Br4923 | MLBr_00310 | pssA | 1e-128 | 77.89% (285) | putative CDP-diacylglycerol-serine o-phosphatidyltransferase |
| M. abscessus ATCC 19977 | MAB_0638c | - | 5e-93 | 57.00% (293) | putative CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. marinum M | MMAR_0753 | pssA | 1e-135 | 87.87% (272) | CDP-diacylglycerol--serine o- phosphatidyltransferase PssA |
| M. avium 104 | MAV_4714 | - | 1e-137 | 81.82% (286) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. smegmatis MC2 155 | MSMEG_0860 | - | 1e-95 | 62.50% (280) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. thermoresistible (build 8) | TH_0812 | - | 7e-83 | 58.30% (271) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
| M. ulcerans Agy99 | MUL_1385 | pssA | 1e-142 | 86.94% (291) | CDP-diacylglycerol--serine o- phosphatidyltransferase PssA |
| M. vanbaalenii PYR-1 | Mvan_0750 | - | 4e-97 | 62.41% (274) | CDP-diacylglycerol--serine O-phosphatidyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0436c|M.tuberculosis_H37Rv MIGKPRGRRG-VNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAA
Mb0444c|M.bovis_AF2122/97 MIGKPRGRRG-VNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAA
MMAR_0753|M.marinum_M --------------------MTVLSICAGLTSIKFALEHQPVPAMALIAA
MUL_1385|M.ulcerans_Agy99 MTTKPRSRRA-VNLQILPSAMTVLSICAGLTSIKFALEHQPVPAMALIAA
MAV_4714|M.avium_104 MISKPRGRRA-VNLQILPSAMTVLSVCAGLTSIRFALEHQPKAAMALIAA
MLBr_00310|M.leprae_Br4923 MTSRPRSRRA-VNLQILPSSMTVLSICAGLTSIRFALEHQPKAAIALIAA
MAB_0638c|M.abscessus_ATCC_199 MISSPVPKRP-VHIRILPSVMTVLAICGGLSSIKFAFDGKPYISLTLIAA
Mflv_0154|M.gilvum_PYR-GCK --MRPRIKTPVVSVRILPSAMTVAAICLGLSAVKFALDGRPTEAMAFLAI
Mvan_0750|M.vanbaalenii_PYR-1 --MRPRIKAPIVSVRILPSAMTVAAICLGLSAVKFALDNRPTEAMAFLAI
MSMEG_0860|M.smegmatis_MC2_155 -MIKARIKRPSFTVRMLPSALTVAAICLGLSAVKMALDNRPTEAMAFLAA
TH_0812|M.thermoresistible__bu --MKPRLKRPPGLKLVLPSGMTVAAICLALTSVKFAHDGSITPALALLAV
:** ::* .*:::::* : :::::*
Rv0436c|M.tuberculosis_H37Rv AAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKW
Mb0444c|M.bovis_AF2122/97 AAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKW
MMAR_0753|M.marinum_M AAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVTMLSKW
MUL_1385|M.ulcerans_Agy99 AAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVTMLSKW
MAV_4714|M.avium_104 AAILDGLDGRVARILDAQSRMGEEIDSLADAVNFGVTPAIVLYVTLLTTS
MLBr_00310|M.leprae_Br4923 AAILDGLDGRVARILGAESRMGEEIDSLADAVNFGVAPAVVLYATMLSTT
MAB_0638c|M.abscessus_ATCC_199 AAILDGLDGRIARLLDATSRMGAEIDSLADAVNFGVAPAVVLYISMLADT
Mflv_0154|M.gilvum_PYR-GCK AAILDALDGRLARALNATSKMGEEIDSLADAVNFGVAPAFIVYGTLLSTS
Mvan_0750|M.vanbaalenii_PYR-1 AAILDALDGRLARALKATSRMGEEIDSLADAVNFGVAPAFIVYGTLLSTS
MSMEG_0860|M.smegmatis_MC2_155 AAILDALDGRVARMLKATSKMGEEIDSLADAVNFGVAPAFIVYGTLLSHS
TH_0812|M.thermoresistible__bu AAILDALDGRIARMLNATSKMGEEIDSLADAVNFGVAPAFIVYWTLLPDS
*****.****:** * * *:** *************:**.::* ::*.
Rv0436c|M.tuberculosis_H37Rv PVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMPAPAGAVSM
Mb0444c|M.bovis_AF2122/97 PVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMPAPAGAVSM
MMAR_0753|M.marinum_M QVGWVVVLLYAVCVVLRLARFNALLDDGTQPAYAHEFFVGMPAPAGAVSM
MUL_1385|M.ulcerans_Agy99 QVGWVVVLLYAVCVVLRLARFNALLDDGTQPAYAHEFFVGMPAPAGAVSM
MAV_4714|M.avium_104 PAGWVAILLYAVCVVLRLARFNALLDDGSQPAYTHEFFVGMPAPAGAVSM
MLBr_00310|M.leprae_Br4923 PVGWVAVLLYPVCVVLRLARFNALLDDGTQPAYTREFFVGMPAPAGAVSV
MAB_0638c|M.abscessus_ATCC_199 PTAWVFSLLYAVCIVLRLARFNTLLDDDTAPAFTKEYFVGVPSPAGALMV
Mflv_0154|M.gilvum_PYR-GCK RIGWIVVLLYAVCIVLRLARFNAMLAVD-QPAYEKKYFTGMPAPAGAIGA
Mvan_0750|M.vanbaalenii_PYR-1 RIGWIVVLLYAVCIVLRLARFNAMLDVE-QPAYEKKYFTGMPAPAGAIGA
MSMEG_0860|M.smegmatis_MC2_155 RVGWIVVLLYAVCIVLRLARFNALLDVD-QPAYEKEYFVGMPAPAGAIGA
TH_0812|M.thermoresistible__bu QVGWIVVLLYAVCIVLRLARFNALLDVD-QPEYAKEFFTGMPAPAGAIGA
.*: ***.**:******:*:: * : :::*.*:*:****:
Rv0436c|M.tuberculosis_H37Rv IGLLALKMQFGEGWW---TSGWFLSFWVTGTSILLVSGIPMKKMHAVSVP
Mb0444c|M.bovis_AF2122/97 IGLLALKMQFGEGWW---TSVWFLSFWVTGTSILLVSGIPMKKMHAVSVP
MMAR_0753|M.marinum_M IGLLALKMQFGEGWW---TSVWFLAFWITGTSMLMVSGIPMKKMHAVAVP
MUL_1385|M.ulcerans_Agy99 IGLLALKMQCGEGWW---TSVWFLAFWITGTSMLMVSGIPMKKMHAVAVP
MAV_4714|M.avium_104 IGLIGLKLQFGDGWW---TSPLFLCIWITGTSILMVSKIPMRKMHAVAVP
MLBr_00310|M.leprae_Br4923 IGLLALKLQFGAGWW---TSTWFLCIWVTGTSMLLISRIPMKKMHTVSVP
MAB_0638c|M.abscessus_ATCC_199 LAPLAAYLQFGDGWW---SSVWAICGWMVFVSMLIVSQIPTAAMKSVSVP
Mflv_0154|M.gilvum_PYR-GCK IGPLAAKMQFGDGWW---TSEPAVVIWMIAVSLLVVSTLPMRKIHTFSVP
Mvan_0750|M.vanbaalenii_PYR-1 IGPLAAKMQFGDGWW---TSEPAVVIWMIGVSLLVVSTLPMRKIHTFAIP
MSMEG_0860|M.smegmatis_MC2_155 IGPLAAKMQWPGEWWNSVTAEWVVIIWMIGVSLLVVSRIPMRKIHTFSVS
TH_0812|M.thermoresistible__bu IGPLAAKMQFGDGWW---TSEWAVSVWMVGVSLLVISAIPMRKIHTFAVP
:. :. :* ** :: : *: .*:*::* :* :::.::.
Rv0436c|M.tuberculosis_H37Rv PNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQH
Mb0444c|M.bovis_AF2122/97 PNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQH
MMAR_0753|M.marinum_M PNLAAVLLAVLAIMAAAAVLAPYILIWVIIIAYVCHIPFAVRSKRWLAEH
MUL_1385|M.ulcerans_Agy99 PNLAAVLLAVLAIMAAAAVLAPYILIWVIIIAYVCHIPFAVRSKRWLAEH
MAV_4714|M.avium_104 PSWAAPLLAVLAICAAAAVLAPYVLIWVIIVAYLCHVPFAVRNQRWLAAH
MLBr_00310|M.leprae_Br4923 PHYAAVFVAMLAIFAAAVVLAPYLLIWVIILTYLCHIPFAIHNQRWLAAH
MAB_0638c|M.abscessus_ATCC_199 PRMVVLLLALVTVAAALLLQYPYVLLLVLIVVYLTHIPFAWRSQRWVAAR
Mflv_0154|M.gilvum_PYR-GCK PNMVAPLLALLAIGVAASILYGYIVILVIIVAYFLHIPFALRTKRFLAAH
Mvan_0750|M.vanbaalenii_PYR-1 PNMVAPLLALLAIGVAASILYGYLVILAIILAYVIHIPFAMRTKRFLSEH
MSMEG_0860|M.smegmatis_MC2_155 PNMAAPLLVLVAIGVAASVFYGYIVIMVIIVAYVIHIPFAVRTKHWVASH
TH_0812|M.thermoresistible__bu ANMVAPLLALLAIGVAAAIQYGYIVIMVIIVAYVLHIPFAVRSKRWLAAH
. .. ::.:::: .* : *::: .:*:.*. *:*** :.::::: :
Rv0436c|M.tuberculosis_H37Rv PEVWDDKPKQRRAVRRASRR---------AHPYRPSMAR-----------
Mb0444c|M.bovis_AF2122/97 PEVWDDKPKQRRAVRRASRR---------AHPYRPSMAR-----------
MMAR_0753|M.marinum_M PEVWGDKPKQRRAARRAIRR---------AQPHRRSVARR--------SV
MUL_1385|M.ulcerans_Agy99 PEVWGDKPKQRRAARRAIRR---------AQPHRRSVARR--------SV
MAV_4714|M.avium_104 PEAWDEAPKQRRAARRAIRR---------AQPNRRSVTR-----------
MLBr_00310|M.leprae_Br4923 PEAWDDKFKQQHDARRAARR---------ACPNRHAVPRLGLLKPGSRSM
MAB_0638c|M.abscessus_ATCC_199 PESWDAKPKERRDLRRDQRRDQRRAFRQAALPKRRTAER-----------
Mflv_0154|M.gilvum_PYR-GCK PEVWDDKPRQQRAARRAIRR---THRTQRAQP-RRSTLRLG---------
Mvan_0750|M.vanbaalenii_PYR-1 PEVWDDKPRQQRAARRAIR---------RAQPHRRSMMRLG---------
MSMEG_0860|M.smegmatis_MC2_155 PESWDVKPKQRRAARRAIR---------RAQPHRRSMARLG---------
TH_0812|M.thermoresistible__bu PXXTGPPPIPPTDSGRVAP----SRPSSSAKACQISGCQPGP--------
* . * * . : : :
Rv0436c|M.tuberculosis_H37Rv --LGLRKPGRRL-
Mb0444c|M.bovis_AF2122/97 --LGLRKPGRRL-
MMAR_0753|M.marinum_M ARLGLRKPGGRL-
MUL_1385|M.ulcerans_Agy99 ARLGLRKPGGRL-
MAV_4714|M.avium_104 --LGLRKPGRRVP
MLBr_00310|M.leprae_Br4923 VRSGLRKPGRRFI
MAB_0638c|M.abscessus_ATCC_199 --LGLRRPGRPR-
Mflv_0154|M.gilvum_PYR-GCK ----LRRPPRG--
Mvan_0750|M.vanbaalenii_PYR-1 ----LRRPPRG--
MSMEG_0860|M.smegmatis_MC2_155 ----LRKPGR---
TH_0812|M.thermoresistible__bu VLAAARLFSRS--
*