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VSWPGLGTRVTVRYRRPAGSMPPLTDAVGRLLAVDPTVRVQTKTGTIVEFSPVDVVALRVLTDAPVRTAA IRALEHAAAAAWPGVERTWLDGWLLRAGHGAVLAANSAVPLDISAHTNTITEISAWYASRDLQPWLAVPD RLLPLPADLAGERREQVLVRDVSTGEPDRSVTLLDHPDDTWLRLYHQRLPLDMATPVIDGELAFGSYLGV AVARAAVTDAPDGTRWVGLSAMRAADEQSATGSAGRQLWEALLGWGAGRGATRGYVRVHDTATSVLAESL GFRLHHHCRYLPAQSVGWDTF*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0428c | - | - | 100% (302) | hypothetical protein Rv0428c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0436c | - | 1e-176 | 99.67% (302) | hypothetical protein Mb0436c |
M. gilvum PYR-GCK | Mflv_0176 | - | 4e-72 | 46.49% (299) | GCN5-related N-acetyltransferase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4188 | - | 2e-62 | 44.26% (305) | hypothetical protein MAB_4188 |
M. marinum M | MMAR_0743 | - | 1e-103 | 66.44% (289) | hypothetical protein MMAR_0743 |
M. avium 104 | MAV_4726 | - | 1e-78 | 54.58% (306) | hypothetical protein MAV_4726 |
M. smegmatis MC2 155 | MSMEG_0830 | - | 1e-76 | 48.53% (307) | acetyltransferase, gnat family protein |
M. thermoresistible (build 8) | TH_3341 | - | 3e-53 | 52.24% (201) | PUTATIVE putative GCN5-related N-acetyltransferase |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_0731 | - | 3e-74 | 47.67% (300) | GCN5-related N-acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Rv0428c|M.tuberculosis_H37Rv -----MVSWPGLGTRVTVRYRRPAGSMPPLTDAVGRLLAVDPTVRVQTKT Mb0436c|M.bovis_AF2122/97 -----MVSWPGLGTRVTVRYRRPAGSMPPLTDAVGRLLAVDPTVRVQTKT MMAR_0743|M.marinum_M ----MTAPWPDLGTRVTIRYRRPAGSVPPLTDAVGHLLAIAPTVRVQTKT MAV_4726|M.avium_104 -----MFSWPDPGTRVTVRYRRPPGSVPPLTDAVGRLLTVDPTVRVQTKT Mflv_0176|M.gilvum_PYR-GCK -----MIELPEIGSRVSLRYRLPTDAERPMTDVVGHIVDAGAVVRIRTRH Mvan_0731|M.vanbaalenii_PYR-1 -----MTELPAVGTRVSLRYRLPTDSDRPFTDVVGHIVDAGPVVRIHTRR MSMEG_0830|M.smegmatis_MC2_155 -----MSELPAVGTRVSLRYRLLAGSAKPLTDVIGHVERISPTVGVRTRS MAB_4188|M.abscessus_ATCC_1997 ------MHLPGLGTRVAIRSRRPPGSVPPFTDTVGELVAAAPTVQVLHKS TH_3341|M.thermoresistible__bu VNRRPMADLPAPGTRVSLRYRLPAGSQPPLSDVVGHLLATEPQIRVRTKT * *:**::* * ..: *::*.:*.: . : : : Rv0428c|M.tuberculosis_H37Rv GTIVEFSPVDVVALRVLTDAPVRTAAIRALEHAAAAAWPGVERTWLDGWL Mb0436c|M.bovis_AF2122/97 GTIVEFSPVDVVALRVLTDAPVRTAAIRALEHAAAAAWPGVERTWLDGWL MMAR_0743|M.marinum_M GAIAEFAPADVVALRVLTDAPIRTAEIRALEHAAAAAWPGTDRSWLDGWL MAV_4726|M.avium_104 GAVVEFAPADVVALRVLTDTPIRTSQIRALEHAAAAAWPAAEQTWLHGWL Mflv_0176|M.gilvum_PYR-GCK GDVVDVDRGDVLAVRVVPEMPVRTGEIRNLEHAAALGWPGVDHEWHHGWL Mvan_0731|M.vanbaalenii_PYR-1 GDVVDVAREDVVAVRAVPEMPVRTGEIRNLEHAAALGWPGTEHQWLDGWL MSMEG_0830|M.smegmatis_MC2_155 GELVEVEPAAIVSVRELSHTPVRASEIRALEHAAALAWPGTEQQWLGGWF MAB_4188|M.abscessus_ATCC_1997 GAVVDISADNIVSVRVLPPVPVLNRDIRSMQRAAALAWPGLEHQWLDGWF TH_3341|M.thermoresistible__bu GAVVQIRPEDVVVARALTAAPVRTAQIRATEHAAALAWPGLEQHWLGGWL * :.:. :: * :. *: ** ::*** .**. :: * **: Rv0428c|M.tuberculosis_H37Rv LRAG----HGAVLAANSAVPLDISAHTNTITEISAWYASRDLQPWLAVPD Mb0436c|M.bovis_AF2122/97 LRAG----HGAVLAANSAVPLDISAHTNTITEISAWYASRDLQPWLAVPD MMAR_0743|M.marinum_M LRAC----HGAPLCANSAVPLDISARPDSIPAILDWYTQRGRTPRLAIPD MAV_4726|M.avium_104 LRAGPPSGRPAGPAADSAVPLDLSAHADAIPEIAGWYQRRGLTPRLAVPD Mflv_0176|M.gilvum_PYR-GCK LRSG----RGATRRANSAVPLQYSS-FAEITEAIDWYARRDLPALISAPD Mvan_0731|M.vanbaalenii_PYR-1 LRHG----QGVTRRANSAVPLRFSS-FSEIAKVADWYAERGLPALVSAPD MSMEG_0830|M.smegmatis_MC2_155 ARAG----LGATSRANSAVPLDMSAQIADLPALVEWYRRRDLPAWLALPE MAB_4188|M.abscessus_ATCC_1997 VRAS----DGHTRRANSAVPLDHSASSRALGELDAWYTERGLPTLLCLPD TH_3341|M.thermoresistible__bu LRAAG----GHTLRADSAVPLGMDADLGSLPEIVRWYADRGLPPLLAVPS * *:***** .: : ** *. . :. *. Rv0428c|M.tuberculosis_H37Rv RLLPLPADLAGERREQVLVRDVSTGEPDR--------SVTLLDHPDDTWL Mb0436c|M.bovis_AF2122/97 RLLPLPAGLAGERREQVLVRDVSTGEPDR--------SVTLLDHPDDTWL MMAR_0743|M.marinum_M RLMPDPAGLTGEHTERVLVGEVATRQADP--------SITVSPRPDDVWR MAV_4726|M.avium_104 RMLTPPPGLACERTERVVVQDLSRPSGD---------------EP----- Mflv_0176|M.gilvum_PYR-GCK RLFRIPQGVPTDAENVVMATDVAPS-----------RTVPVSPTPEDSWL Mvan_0731|M.vanbaalenii_PYR-1 RLLRLPDGVPTDAENLVMATDIAVTGV---------TDAAVSASPDDRWL MSMEG_0830|M.smegmatis_MC2_155 RLLPIRAAGIKPAR--VMVRDVPPGGPDHTAGEGRNIDAQFVSRPDADWL MAB_4188|M.abscessus_ATCC_1997 RLIHPPDDLATSDETVVMVRDLDNAG-----------TDTLPAEPSADWL TH_3341|M.thermoresistible__bu RLLRILDAAPAVHESVMLVGTPRTAAPDP--------DVRLLPRPDAEWL *:: ::. * Rv0428c|M.tuberculosis_H37Rv RLYHQRLP--LDMATPVIDGELAFGSYLG----VAVARAAVTDAPDGTRW Mb0436c|M.bovis_AF2122/97 RLYHQRLP--LDMATPVIDGELAFGSYLG----VAVARAAVTDAPDGTRW MMAR_0743|M.marinum_M GHCDREIA--EHALTAVIDGELAFGSGPQ----AVVARAAVTDAPDGTRW MAV_4726|M.avium_104 ------------------------GVRVD----ASVAQAALSAAPDGARW Mflv_0176|M.gilvum_PYR-GCK RVYQRDVP--VDVLTAVIDGEVGFGELDG----AAVGRVAVTEAPDGTRW Mvan_0731|M.vanbaalenii_PYR-1 ALYRRDVP--VDVLTAVVDGVVGFGELAG----AAVGRVAVTDAPDGTRW MSMEG_0830|M.smegmatis_MC2_155 AGYERKVP--VEVLTAVVDGEVTFASVAG----SAVGRGAVTPAPDGTRW MAB_4188|M.abscessus_ATCC_1997 ALHGDNHPLVVPVLTAVVDGTLGFAAVASEGSTAAIARGAVTEN-----W TH_3341|M.thermoresistible__bu RMSGRDIP--VRVWTAAVDGX----------------------------- Rv0428c|M.tuberculosis_H37Rv VGLSAMRAADEQSATGSAGRQLWEALLGWGAGRGATRGYVRVHD--TATS Mb0436c|M.bovis_AF2122/97 VGLSAMRAADEQSATGSAGRQLWEALLGWGAGRGATRGYVRVHD--TATS MMAR_0743|M.marinum_M VGVSAACTIDDQSPTGPAA-LLYTALLAWGAGRGATRGYTCVPG--TATP MAV_4726|M.avium_104 VGLWVP--PGGHHAEARAG---CEALLAWGAGRGATRAYLAVPDDDAAAL Mflv_0176|M.gilvum_PYR-GCK AGLSAVRVDESARRRGLAR-TLCEGMLTWAHERGATRAYVQVVTENTAAR Mvan_0731|M.vanbaalenii_PYR-1 AGVSAVHVSEDARRQGLAR-RLCAGLLDWAHGRGATRAYVQVVVENTAAR MSMEG_0830|M.smegmatis_MC2_155 LGISSVRVAAQARRQGYAR-AVCDALLAWGAAAGAQRAYVQVEVDNAPAI MAB_4188|M.abscessus_ATCC_1997 LGISAVRVAENQRRRGLAA-QVCDILLGWGAALGARRAYVQVRADNAAAL TH_3341|M.thermoresistible__bu --------XXXAMRSPAAG----------RCGKSTGSPLTRIRSTSVCGI * .: : . Rv0428c|M.tuberculosis_H37Rv VLAESLGFRLHHHCRYLPAQSVGWDTF Mb0436c|M.bovis_AF2122/97 VLAESLGFRLHHHCRYLPAQSVGWDTF MMAR_0743|M.marinum_M GWAESLGLRPHHRRRYLRTPASL---- MAV_4726|M.avium_104 ELAGALGFRLHHRRRYLTVPAGPVG-- Mflv_0176|M.gilvum_PYR-GCK TLYESMGFVVHHRSRYVRAQDLL---- Mvan_0731|M.vanbaalenii_PYR-1 ALYASMGFRVHHHSRYVRAQDLL---- MSMEG_0830|M.smegmatis_MC2_155 TLYSSLGFRLHHQTRYVAAEDLTTLR- MAB_4188|M.abscessus_ATCC_1997 ALYPTLGFTEQHRYRYAQIRAAGHEK- TH_3341|M.thermoresistible__bu PIASSTSLTV----------------- : .: