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M. tuberculosis H37Rv Rv0412c (-)

annotation: POSSIBLE CONSERVED MEMBRANE PROTEIN
coordinates: 498300 - 499619
length: 439

TVELAHPSTEPLGSRSPAEPAHPRRWFISTTPGRIMTIGIVLAALGVASAFATSTTIEHRQQVLTAVLDH
TEPLSFAAGRLYTTLSVADAAAATAFIAQAEPGGVRLRYEQAITDASVAVTRASSGLTDESLVQLLGRIN
AELAVYTGLVEIARANNRAGNPVGSSYLSEASGLMQSTILPDAQRLYQATSARVDRETTASTQIPAPVIL
VVATTVVFGAFAHRWLARRTRRRINPGLVVGALGILVMVVWVGTALTISTTASRSAKDTAAESLKTITNL
AITAQQARADETLSLIRRGDEEVRKQAFYQRIDAMQRQLNDYMARRHAVDKPDLQGADQLLVRWRQANDR
INSDISVGNYRAATQVALGKGEDDATPAFDKLDEALTKAMGQSRTQLRHDILNAHRGLAGAQVGGVVLSL
GAAIAVALGLWPRLKEYR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0412c--100% (439)POSSIBLE CONSERVED MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0420c-0.099.77% (439) hypothetical protein Mb0420c
M. gilvum PYR-GCKMflv_0200-0.076.31% (439) hypothetical protein Mflv_0200
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4222-1e-15460.96% (438) hypothetical protein MAB_4222
M. marinum MMMAR_0715-0.090.21% (439) hypothetical protein MMAR_0715
M. avium 104MAV_4749-0.086.33% (439) hypothetical protein MAV_4749
M. smegmatis MC2 155MSMEG_0788-0.077.12% (437) hypothetical protein MSMEG_0788
M. thermoresistible (build 8)TH_2309-0.075.51% (437) POSSIBLE CONSERVED MEMBRANE PROTEIN
M. ulcerans Agy99MUL_2808-0.089.75% (439) hypothetical protein MUL_2808
M. vanbaalenii PYR-1Mvan_0705-0.075.40% (439) hypothetical protein Mvan_0705

CLUSTAL 2.0.9 multiple sequence alignment


Rv0412c|M.tuberculosis_H37Rv        ---MTVELAHPSTEPLGSRSPAEPAHPRRWFISTTPGRIMTIGIVLAALG
Mb0420c|M.bovis_AF2122/97           ---MTVELAHPSTEPLGSRSPAEPAHPRRWFISTTPGRIMTIGIVLAALG
MMAR_0715|M.marinum_M               ---MTVELAHPSTEPLGSRSPAEPAHPRWWFVSTTPGRILTIGIVLAALG
MUL_2808|M.ulcerans_Agy99           ---MTVELAHPSTEPLGSRSPTEPAHPRWWFVSTTPGRILTIGIVLAALG
MAV_4749|M.avium_104                ---MTVELAHPSTEPQGSRSPAEPAHPRWWFISTTPGRILTIGIVLAALG
Mflv_0200|M.gilvum_PYR-GCK          ---MTVELAHPSTEPLASRSPTAPSHPRWWFLWTTPGRILSIGMVLAALV
Mvan_0705|M.vanbaalenii_PYR-1       ---MTVELAHPSTEPLASRSPTAPSHPRWWFLWTTPGRILSIGMVLAALV
MSMEG_0788|M.smegmatis_MC2_155      -----MELAHPSTEPLASRSPTTPAHPRWWFLWTTPGRILTIGLVLSALV
TH_2309|M.thermoresistible__bu      -----VELAHPSTEPLASRSPTNPTHSRWWFLWTTPGRILTIGIVLSALA
MAB_4222|M.abscessus_ATCC_1997      MTVGTTRLAHPSTEPVGATTRIAPAHPWWWFLKSTPGKILMLGIALAAAG
                                          .******** .: :   *:*.  **: :***:*: :*:.*:*  

Rv0412c|M.tuberculosis_H37Rv        VASAFATSTTIEHRQQVLTAVLDHTEPLSFAAGRLYTTLSVADAAAATAF
Mb0420c|M.bovis_AF2122/97           VASAFATSTTIEHRQQVLTAVLDHTEPLSFAAGRLYTTLSVADAAAATAF
MMAR_0715|M.marinum_M               VASAFATSTTINHRQQVLTTVLDHTEPLSFAAGRLYTTLSVADAAAATAF
MUL_2808|M.ulcerans_Agy99           VASAFATSTTINHRQQVLTTVLDHTEPLSFAAGRLYTTLSVADAAAATAF
MAV_4749|M.avium_104                GLSAFATSTTINHRQQVLTTVLNHTEPLSFAAGRLYTTLSVADAAAATAF
Mflv_0200|M.gilvum_PYR-GCK          IASAFATSTTINDRQQALTAVLNHTEPLAFAAGQLYTTLSVADAAAATAF
Mvan_0705|M.vanbaalenii_PYR-1       VGSAFATSTTINDRQQALTTVLNHTEPLAFAAGQLYTTLSVADAAAATAF
MSMEG_0788|M.smegmatis_MC2_155      IASAFATSTTVNDRQQALTTVLDHTEPLSFAAGRLYTTLSVADAAAATAF
TH_2309|M.thermoresistible__bu      IASAFATSTTINDRQQALTTVLNHTEPLAFAAGQLYTKLSVADAAAATAF
MAB_4222|M.abscessus_ATCC_1997      VLSAVATSASVQNRQEALSTVLNHTEPLAYSAGQLYSTLSVADAAATTAF
                                      **.***::::.**:.*::**:*****:::**:**:.********:***

Rv0412c|M.tuberculosis_H37Rv        IAQAEPGGVRLRYEQAITDASVAVTRASSGLTDESLVQLLGRINAELAVY
Mb0420c|M.bovis_AF2122/97           IAQAEPGGVRLRYEQAITDASVAVTRASSGLTDESLVQLLGRINAELAVY
MMAR_0715|M.marinum_M               IAQAEPRAVRLRYEQAITDASVAVTRASSGLTDESLVQLLGRINAELSVY
MUL_2808|M.ulcerans_Agy99           IAQAEPRAVRLRYEQAITDASVAVTRASSGLTDESLVQLLGRINAELSVY
MAV_4749|M.avium_104                IAEAEPPPVRQRYEQAITDAAVAVTRASSGLTDEPMVQLLGRINAELAVY
Mflv_0200|M.gilvum_PYR-GCK          IAGAEPRPVRQRYEQAITDASVAVTRASSGLTEESLVQLLGRINARLAVY
Mvan_0705|M.vanbaalenii_PYR-1       IAGAEPRAVRQRYEQAITDASVAVTRASSGLTEEELVQLLGRINARLAVY
MSMEG_0788|M.smegmatis_MC2_155      IAGAEPRDVRQRYEQAIVDASVAVTRASSGLTDEALIQLLGRINARLAVY
TH_2309|M.thermoresistible__bu      IAGAEPPEVRQRYEQAITDAAVAVTRAASGLTDEELVALLGRVNAQLAVY
MAB_4222|M.abscessus_ATCC_1997      IAGTEPQSVRERYEQAITDASTALVAASSGLTDRPMQELLSRINAELSVY
                                    ** :**  ** ******.**:.*:. *:****:. :  **.*:**.*:**

Rv0412c|M.tuberculosis_H37Rv        TGLVEIARANNRAGNPVGSSYLSEASGLMQSTILPDAQRLYQATSARVDR
Mb0420c|M.bovis_AF2122/97           TGLVEIARANNRAGNPVGSSYLSEASGLMQSTILPDAQRLYQATSARVDR
MMAR_0715|M.marinum_M               TGLVEIARTNNRAGNPVGSSYLSEASGLMQSTILPDAQQLYEATSTRVDS
MUL_2808|M.ulcerans_Agy99           TGLVEIARTNNRAGNPVGSSYLSEASGLMQSTILPDAQQLYEATSTRVDS
MAV_4749|M.avium_104                TGLIETARTNNRQGNPVGSSYLSEASGLMQSTILPDAARLYQATSKRVDE
Mflv_0200|M.gilvum_PYR-GCK          TGLVETARTNNRAGNPVGSSYLSEASALMQLQILPDAQRLYEETSARVDA
Mvan_0705|M.vanbaalenii_PYR-1       TGLVETARTNNRAGNPVGSSYLSEASALMQQQILPDAQRLYEETSARVDA
MSMEG_0788|M.smegmatis_MC2_155      TGLIETARTNNRAGNPVGSSYLSEASSMMQTQILPDAQRLYEETSARVDA
TH_2309|M.thermoresistible__bu      TGLVETARTNNRAGNPVGSSYLSEASALMQSQILPDAQRLYEATSARVDV
MAB_4222|M.abscessus_ATCC_1997      TGLIETARTNNRASNPVGASYLSEASSLMQRTILPDAQLLYEETANRADQ
                                    ***:* **:*** .****:*******.:**  *****  **: *: *.* 

Rv0412c|M.tuberculosis_H37Rv        ETTASTQIPAPVILVVATTVVFGAFAHRWLARRTRRRINPGLVVGALGIL
Mb0420c|M.bovis_AF2122/97           ETTASTQIPAPVILVVATTVVFGAFAHRWLARRTRRRINPGLVVGALGIL
MMAR_0715|M.marinum_M               ETTASTQIPAPVILVVATTVAFGAFAHRWLARRTRRRINPGLVVGALGIL
MUL_2808|M.ulcerans_Agy99           ETTASTQIPAPVILVVATTVAFGAFAHRWLARRTKRRINPGLVVGALGIL
MAV_4749|M.avium_104                ETTASTQIPAPVIMVVGATVVFGAFAHRWLARRTRRRINPGLVVGALAIL
Mflv_0200|M.gilvum_PYR-GCK          ETTASTRIPIPVILVVTATLLFGVFANRWLAKRTRRRVNIGFVAGGLAVL
Mvan_0705|M.vanbaalenii_PYR-1       ETTASARIPTPVILVVVATLLFGVFANRWLAKRTRRRVNIGFVAGGLAVL
MSMEG_0788|M.smegmatis_MC2_155      ETTASTQIPLPVILVVLATLLFGAFANRWLARRTRRRVNIGFVAGGLAVL
TH_2309|M.thermoresistible__bu      ETTASARIPAPVILVVLATLLFGLFANRWLARRTRRRVNIGFVAGGLAVL
MAB_4222|M.abscessus_ATCC_1997      ETSASTRVPFPVILIVLSTMIAGVLGHRWLSKRTRRMINPGMLAGGLALL
                                    **:**:::* ***::* :*:  * :.:***::**:* :* *::.*.*.:*

Rv0412c|M.tuberculosis_H37Rv        VMVVWVGTALTISTTASRSAKDTAAESLKTITNLAITAQQARADETLSLI
Mb0420c|M.bovis_AF2122/97           VMVVWVGTALTISTTASRSAKDTAAESLKTITNLAITAQQARADETLSLI
MMAR_0715|M.marinum_M               VMVVWVGTALTLSTAASRIAKDTAAESLKTVTNLAITAQQARADETLSLI
MUL_2808|M.ulcerans_Agy99           VMVVWVGTALTLSTAASRIAKDTAAESLKTVTNLAITAQQARADETLSLI
MAV_4749|M.avium_104                VMVVWVGTALTISTTASRSAKDTAAESLKTVTNVAITAQQARADETLSLI
Mflv_0200|M.gilvum_PYR-GCK          IMLMWVGTALIISTADSRSAKETAAESLKTVTTLAITAQQARADETLSLI
Mvan_0705|M.vanbaalenii_PYR-1       IMLMWVGTALVISTSDSRSAKETAAESLKTVTTLAITAQQARADETLSLI
MSMEG_0788|M.smegmatis_MC2_155      IMLIWVSTALVISTSDSRSAKETAAESLKTITTLAITAQQARADETLALI
TH_2309|M.thermoresistible__bu      IMVVWVGTALTISTADSRSAKNTAAESLKTVTNLAITAQQARADETLALI
MAB_4222|M.abscessus_ATCC_1997      LMVVWVGIALAVSASLGTEARNGGAHSLKTITQLVISAQQARADETLALI
                                    :*::**. ** :*:: .  *:: .*.****:* :.*:**********:**

Rv0412c|M.tuberculosis_H37Rv        RRGDEEVRKQAFYQRIDAMQRQLNDYMARRHAVDKPDLQGADQLLVRWRQ
Mb0420c|M.bovis_AF2122/97           RRGDEEVRKQAFYQRIDAMQRQLNDYMARRHAVDKPDLQGADQLLVRWRQ
MMAR_0715|M.marinum_M               RRGDQEVRKQSFYQRIEDMHRQLDEYMARPDAVDKPDLQGAEQLLVRWQQ
MUL_2808|M.ulcerans_Agy99           RRGDQEVRKQSFYQRIEDMHRQLDEYMARPDAVDKPDLQGAEQLLVRWQQ
MAV_4749|M.avium_104                RRGDEEKRKQSFYQRLDSMHRQLDEYMSRSDAVDKPDLEGADQLLLRWRQ
Mflv_0200|M.gilvum_PYR-GCK          RRGDEDIRKQSYYQRIDEMKQQLARYVARDDSIDKSDLADADALLDRWRA
Mvan_0705|M.vanbaalenii_PYR-1       RRGDENLRKQSYYQRIDEMKQQLARYLSRDDSIDKTDLTDAEALLDRWRA
MSMEG_0788|M.smegmatis_MC2_155      RRGDENVRKQSYYQRIDVMQQQLSDYLARDIGIDKSDLAGAEQLLTRWRA
TH_2309|M.thermoresistible__bu      RRGDETTRKESFYQRIETMQQQLADYLERRDSIDKSDLHDAQRLLERWRV
MAB_4222|M.abscessus_ATCC_1997      RRGDENVRKKSYYDRIDEMDRKIGEYLSNPDAIARSDLEHAQQLLTRWRQ
                                    ****:  **:::*:*:: *.:::  *: .  .: :.**  *: ** **: 

Rv0412c|M.tuberculosis_H37Rv        ANDRINSDISVGNYRAATQVALGKGEDDATPAFDKLDEALTKAMGQSRTQ
Mb0420c|M.bovis_AF2122/97           ANDRINSYISVGNYRAATQVALGKGEDDATPAFDKLDEALTKAMGQSRTQ
MMAR_0715|M.marinum_M               ANDRINSYISVGNYRAATQVALGESEDDSTPAFDKLDEALTRAMDQSRNH
MUL_2808|M.ulcerans_Agy99           ANDRINSYISVGNYRAATQVALGESEDDSTPAFDKLDEALTRAMDQSRNH
MAV_4749|M.avium_104                ANDRITSYISVGNYRAATQVALGSSEEDSTPAFDKLQDELMKAMDQGRIH
Mflv_0200|M.gilvum_PYR-GCK          ADDRITAYIAVGNYQAATQVALGTGEDDATPAFDKIDEALTRGIDQSRTQ
Mvan_0705|M.vanbaalenii_PYR-1       ADDRISAYIAVGNYQAATQVALGTGEDDSTPAFDKLDAALTKGIDQSRTQ
MSMEG_0788|M.smegmatis_MC2_155      ADDRINAYIAVGNYQAATQVALGTGEDDSTPAFDKLDQALSKAIEHSRNQ
TH_2309|M.thermoresistible__bu      ADDRINAYIAVGNYQAATQVALGTGDGDSTPAFDQLDAALNKAIEKSRTE
MAB_4222|M.abscessus_ATCC_1997      ADDRINAYIGVGNYQAATQVALGNSDSDSTPAFDSLDTSLRSAVQDSRRQ
                                    *:***.: *.****:******** .: *:*****.::  *  .: ..* .

Rv0412c|M.tuberculosis_H37Rv        LRHDILNAHRGLAGAQVGGVVLSLGAAIAVALGLWPRLKEYR
Mb0420c|M.bovis_AF2122/97           LRHDILNAHRGLAGAQVGGVVLSLGAAIAVALGLWPRLKEYR
MMAR_0715|M.marinum_M               LRTDVRNARRGLAGAQMGGVVLSLSAAIAVALGLWPRLKEYR
MUL_2808|M.ulcerans_Agy99           LRTDVRNARRGLAGAQMGGVVLSLSAAIAVALGLWPRLKEYR
MAV_4749|M.avium_104                LRNDVINARSGLSGAQVGGVVLSLGAAIAVALGLWPRLKEYR
Mflv_0200|M.gilvum_PYR-GCK          LRSDIVNARRVLSGATVGAALLSVVAAVSVALGIWPRLSEYR
Mvan_0705|M.vanbaalenii_PYR-1       LRNDIVNARRVLSGATVGAAALSVVAAVAVALGIWPRLSEYR
MSMEG_0788|M.smegmatis_MC2_155      LRTDIANARRVLSGATVGAALLSVAAAVAVALGIWPRLSEYR
TH_2309|M.thermoresistible__bu      LRNNIVNARRVLSGATAGAAALSAVAAIAVALGLWPRLNEYR
MAB_4222|M.abscessus_ATCC_1997      LRSGVLNAERALTLSSAGALILSVGGAICVGVGLWPRLSEYR
                                    ** .: **.  *: :  *.  **  .*:.*.:*:****.***