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M. tuberculosis H37Rv Rv0319 (pcp)

annotation: pyrrolidone-carboxylate peptidase
coordinates: 387148 - 387816
length: 222

MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESIAAAQQAIAEIEPALVIMLGE
YPGRSMITVERLAQNVNDCGRYGLADCAGRVLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDA
AGTFVCNHLMYGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSA
DIREPIPSRLQI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0319pcp-100% (222)pyrrolidone-carboxylate peptidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0327pcp1e-125100.00% (222) pyrrolidone-carboxylate peptidase
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0598pcp1e-10782.43% (222) pyrrolidone-carboxylate peptidase, Pcp
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv0319|M.tuberculosis_H37Rv      MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESI
Mb0327|M.bovis_AF2122/97         MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESI
MMAR_0598|M.marinum_M            MTKVLVTGFGPYGVTPDNPAQFTAEALDGRTIAGATVVSRIVPGAYFDSI
                                 *:************** ****:*** ***********:*****.::*:**

Rv0319|M.tuberculosis_H37Rv      AAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGR
Mb0327|M.bovis_AF2122/97         AAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGR
MMAR_0598|M.marinum_M            AAAEQAIAEVDPQLVIMLGEYPGRAMLTVERLAQNINDCGRYGLADTAGK
                                 ***:*****::* ***********:*:********:********** **:

Rv0319|M.tuberculosis_H37Rv      VLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLM
Mb0327|M.bovis_AF2122/97         VLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLM
MMAR_0598|M.marinum_M            VLVGEPTDPDGPVAYHATVPVHEMVLAMRAAGIPADVSDAAGTFVCNHLM
                                 ********* ***********: ****** **:*****************

Rv0319|M.tuberculosis_H37Rv      YGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTA
Mb0327|M.bovis_AF2122/97         YGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTA
MMAR_0598|M.marinum_M            YGVLHHIATQNLPIRAGWVHLPCLPMVAALDRNLGVPSMSVETAVAGLVA
                                 ******:* :.**:****:****** *****:*********:*****:.*

Rv0319|M.tuberculosis_H37Rv      GIEAAIRQSADIREPIPSRLQI
Mb0327|M.bovis_AF2122/97         GIEAAIRQSADIREPIPSRLQI
MMAR_0598|M.marinum_M            GIEAAVQHSADTREPVPSRLQI
                                 *****:::*** ***:******