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M. tuberculosis H37Rv Rv0316 (-)

annotation: POSSIBLE MUCONOLACTONE ISOMERASE
coordinates: 384535 - 385149
length: 204

MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAADDNGELEQL
LASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPEL
AGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPIRMP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0316--100% (204)POSSIBLE MUCONOLACTONE ISOMERASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0324-1e-119100.00% (204) muconolactone isomerase
M. gilvum PYR-GCKMflv_1359-3e-0833.33% (93) muconolactone Delta-isomerase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0568-6e-7967.49% (203) muconolactone isomerase
M. avium 104MAV_2047-4e-6359.80% (204) muconolactone delta-isomerase family protein
M. smegmatis MC2 155MSMEG_1912-4e-1034.69% (98) muconolactone delta-isomerase 1
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2213-1e-3774.47% (94) muconolactone isomerase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv0316|M.tuberculosis_H37Rv         MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRP
Mb0324|M.bovis_AF2122/97            MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRP
MMAR_0568|M.marinum_M               MEFLVSMTIEVPRGTPAAEIDRARVSENAGWRELGAQGRLLRLWRPPCGP
MUL_2213|M.ulcerans_Agy99           --------------------------------------------------
MAV_2047|M.avium_104                MEFLVAATTQVPDGTPAEAVDDLRARESARCRELARQGQLLRLWRAPSPP
Mflv_1359|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1912|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv0316|M.tuberculosis_H37Rv         GEWRTLGLFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGIT
Mb0324|M.bovis_AF2122/97            GEWRTLGLFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGIT
MMAR_0568|M.marinum_M               GQWCTLGLFAARDEPSLRKLLVTVPVQDWRSDEVAVLGAHPNDPLGAGVT
MUL_2213|M.ulcerans_Agy99           --------------------------------------------------
MAV_2047|M.avium_104                GRWRTLGLFAAADDNALEQLLASTPLRAWRTEEVTPLPVHPNDPTARLIT
Mflv_1359|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1912|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv0316|M.tuberculosis_H37Rv         IAPGKG--PEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVR
Mb0324|M.bovis_AF2122/97            IAPGKG--PEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVR
MMAR_0568|M.marinum_M               PRPGKG--PEFLITTTLTVPSGTSARVVDDATEREARRCHELAEAGHLVR
MUL_2213|M.ulcerans_Agy99           -----------MITTTLTVPSGTSVRVVDDATEREARRCHELAEAGHLVR
MAV_2047|M.avium_104                PEPVSGGAAEFLQAITIRVPADAPQRVVDDVLAREAERAVELGAQGCLQR
Mflv_1359|M.gilvum_PYR-GCK          --------MLFHVRMDVAIPPDMDPQVRAQTVHREKEYSQQLQRDGKWPH
MSMEG_1912|M.smegmatis_MC2_155      --------MHFHVRMDVRLPHDMDQDTLAQLVAREKAYSQQLQRSGKWPH
                                                    : :* .    .  :   **   . :*   *   :

Rv0316|M.tuberculosis_H37Rv         LWALPDGPDGQRTLGLWRARDPGELMAILESLPLAGWMTIETT-PLSPHP
Mb0324|M.bovis_AF2122/97            LWALPDGPDGQRTLGLWRARDPGELMAILESLPLAGWMTIETT-PLSPHP
MMAR_0568|M.marinum_M               FWALPAGPDGPRMLGLWRARDPGELMAVVESLPLSGWMTIETT-PLRPHP
MUL_2213|M.ulcerans_Agy99           FWALPAGPDGPRMLGLWRARDPGELMAVVESLPLSGWMTIETT-PLRPHP
MAV_2047|M.avium_104                LWWLHSGPGDPRVLALWRTADTESLAAVLRSLPLHAWLQVDTTTPLHTHP
Mflv_1359|M.gilvum_PYR-GCK          IWRIVGEYAN---YSIFDVDSNDELHQILSGLPLFPYMKIHVT-PLAVHP
MSMEG_1912|M.smegmatis_MC2_155      IWRIVGEYAN---FSIFDVETNDELHSVISGLPLFPYMDIHVT-PLARHP
                                    :* :     .    .:: .    .*  :: .***  :: :..* **  **

Rv0316|M.tuberculosis_H37Rv         DDPIRMP---------------
Mb0324|M.bovis_AF2122/97            DDPIRMP---------------
MMAR_0568|M.marinum_M               SDPIRLSWARRAGDWRKPNRQC
MUL_2213|M.ulcerans_Agy99           SDPIRLSWARRAGDWRKPNRQC
MAV_2047|M.avium_104                DDPVSGSLAGR-----------
Mflv_1359|M.gilvum_PYR-GCK          SDVNAG----------------
MSMEG_1912|M.smegmatis_MC2_155      SDIDQG----------------
                                    .*