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M. tuberculosis H37Rv Rv0193c (-)

annotation: hypothetical protein Rv0193c
coordinates: 224724 - 226571
length: 615

IQISRDMSSLGQTATTQALPDNSDGIQLTKFAADDILPLEYAPPIGPELVSQDQLPAAWAYKRFRDLDDK
ESYRRKLLQELTDALAAQGSEAAEIATAALRDLIDQMAEQGAVVLADIVESDDFLELVKRYDELMAREGS
RSFIHRFLDLRRSPGMLTDPAVNGALVHPLMIALISYAVGGPIRMIDARGKDAEPLSVLAQDNMLHIDNT
PFNDEYKILITWRRGTAQGPAGQNFTFLPGTHKLARTCFVNEDGVPWSSENASIFTTPDSIRKVFDAQRQ
LGGQDHPTVIEVTDSERPLSGVFAAGSLVHHRFRTASGSARSCIILVFHRVADNPGRMVSDVEDSSDVSL
SELLTRGVPDESYQQRFIATLCAAADEIAELLLKWKKTPQRPVSLPLQTKQIDGARFEEWISAATKAPEV
REIRNRELTIPYGEVLSAEEFFDLIWRLMRFDKHGPLDLILYHDNREEPRKWARNLIREMSADRLYERLL
GWLADIQQPRPADCLRPLQIHALISEVLKTLPLDEDQDPPADWHFDLLGMSHAEAARSVKHLLEDVAEAL
LRCEDMAAYLSTSLFAFWAVDAAYSLDGRRNLVVKDCARRLLRHYTMLSLTCFQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0193c--100% (615)hypothetical protein Rv0193c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0199c-0.099.67% (615) hypothetical protein Mb0199c
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_5224-0.078.44% (603) hypothetical protein MMAR_5224
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4299-0.077.28% (603) hypothetical protein MUL_4299
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5224|M.marinum_M             MGFSDLIIRYRTFTSQLGVSLMQLGATLSSTDNANGIQLAKFNSDDVLPM
MUL_4299|M.ulcerans_Agy99         MVFSDLIIRYRTFTSQLGVSLMQLGATLSSTDNANGIQLAKFNSDDVLPM
Rv0193c|M.tuberculosis_H37Rv      -----MIQISRDMS-----SLGQTATTQALPDNSDGIQLTKFAADDILPL
Mb0199c|M.bovis_AF2122/97         -----MIQISRDMS-----SLGQTATTQALPDNSDGIQLTKFAADDILPL
                                       :*   * ::     ** * .:* : .**::****:** :**:**:

MMAR_5224|M.marinum_M             NFAPPIGPELVSPEELPAAWAYKRFRDLEEKESYRSTLLAELTKAFEILS
MUL_4299|M.ulcerans_Agy99         NFAPPIGPELVSPEELPAAWAYKRFRDLEEKESYRSTLLAELTKAFEILS
Rv0193c|M.tuberculosis_H37Rv      EYAPPIGPELVSQDQLPAAWAYKRFRDLDDKESYRRKLLQELTDALAAQG
Mb0199c|M.bovis_AF2122/97         EYAPPIGPELVSQDQLPAAWAYKRFRDLDDKESYRRKLLQELTDALAAQG
                                  ::********** ::*************::***** .** ***.*:   .

MMAR_5224|M.marinum_M             PQDAATATAGLQDLLGQMAEQGAVVLADIVESDAFLELVARYDEIMAQEG
MUL_4299|M.ulcerans_Agy99         PQDAATATAGLQDLLGQMAEQGAVVLADIVESDAFLELVARYDEIMAQEG
Rv0193c|M.tuberculosis_H37Rv      SEAAEIATAALRDLIDQMAEQGAVVLADIVESDDFLELVKRYDELMAREG
Mb0199c|M.bovis_AF2122/97         SEAAEIATAALRDLIDQMAEQGAVVLADIVESDDFLELVKRYDELMAREG
                                  .: *  ***.*:**:.***************** ***** ****:**:**

MMAR_5224|M.marinum_M             SGSFIHRFVDLRRTVGLLTDPEVNNPMVHPLMITLISYAVGGPIRMVDAR
MUL_4299|M.ulcerans_Agy99         SGSFIHRFVDLRRIVGLLTDPEVNNPMVHPLMITLISYAVGGPIRMVDER
Rv0193c|M.tuberculosis_H37Rv      SRSFIHRFLDLRRSPGMLTDPAVNGALVHPLMIALISYAVGGPIRMIDAR
Mb0199c|M.bovis_AF2122/97         SRSFIHRFLDLRRSPGMLTDPAVNGALVHPLMIALISYAVGGPIRMIDAR
                                  * ******:****  *:**** **..:******:************:* *

MMAR_5224|M.marinum_M             AKDAEPLSVLAQDNMLHIDNTPFNDEYKIIVTWRRGTAKGPAGQNFTFLP
MUL_4299|M.ulcerans_Agy99         AKDAEPLSVLAQDNMLHIDNTPFNDEYKIIVTWRRGTAKGPAGQNFTFLP
Rv0193c|M.tuberculosis_H37Rv      GKDAEPLSVLAQDNMLHIDNTPFNDEYKILITWRRGTAQGPAGQNFTFLP
Mb0199c|M.bovis_AF2122/97         GKDAEPLSVLAQDNMLHIDNTPFNDEYKILITWRRGTAQGPAGQNFTFLP
                                  .****************************::*******:***********

MMAR_5224|M.marinum_M             GTHQLARTCFVNEAGEPWSSENASIFTTTERIRRVFDAQMQLRDQDRPVV
MUL_4299|M.ulcerans_Agy99         GTHQLARTCFVNEAGEPWSSENASIFTATERIRRVFDAQMQLRDQDRPVV
Rv0193c|M.tuberculosis_H37Rv      GTHKLARTCFVNEDGVPWSSENASIFTTPDSIRKVFDAQRQLGGQDHPTV
Mb0199c|M.bovis_AF2122/97         GTHKLARTCFVNEDGVPWSSENASIFTTPDSIRKVFDAQRQLGGQDHPTV
                                  ***:********* * ***********:.: **:***** ** .**:*.*

MMAR_5224|M.marinum_M             IEVSDSERPLSTVFAAGSLVHHRFRTASGNARSCIIMAFHRVADNPGRLV
MUL_4299|M.ulcerans_Agy99         IEVSGSERPLSTVFAAGSLVHHRFRTASGNARSCIIMAFHRVADNPGRLV
Rv0193c|M.tuberculosis_H37Rv      IEVTDSERPLSGVFAAGSLVHHRFRTASGSARSCIILVFHRVADNPGRMV
Mb0199c|M.bovis_AF2122/97         IEVTDSERPLSSVFAAGSLVHHRFRTASGSARSCIILVFHRVADNPGRMV
                                  ***:.****** *****************.******:.**********:*

MMAR_5224|M.marinum_M             SDVEDTPSASLSELLTSGVPDESYQQRFITTLCAAAGQIAELLAKWKSTP
MUL_4299|M.ulcerans_Agy99         SDVEDTPSASLSELLTSGVPDESYQQRFITTLCAAAGQIAELLAKWKSTP
Rv0193c|M.tuberculosis_H37Rv      SDVEDSSDVSLSELLTRGVPDESYQQRFIATLCAAADEIAELLLKWKKTP
Mb0199c|M.bovis_AF2122/97         SDVEDSSDVSLSELLTRGVPDESYQQRFIATLCAAADEIAELLLKWKKTP
                                  *****:...******* ************:******.:***** ***.**

MMAR_5224|M.marinum_M             ERPVPLPLQERQIDGRRFEEWISASTEAPPVQEIRNREQPIPYGEVLSSE
MUL_4299|M.ulcerans_Agy99         ERPVPLPLQERQIDGRRFEEWISASTEASPVQEIRNREQPIPHGEVLSSE
Rv0193c|M.tuberculosis_H37Rv      QRPVSLPLQTKQIDGARFEEWISAATKAPEVREIRNRELTIPYGEVLSAE
Mb0199c|M.bovis_AF2122/97         QRPVSLPLQTKQIDGARFEEWISAATEAPEVREIRNRELTIPYGEVLSAE
                                  :***.**** :**** ********:*:*. *:****** .**:*****:*

MMAR_5224|M.marinum_M             EFFDLVWRLMRFDKHGPLDLVLYHDNREEPRKWARNLIREMSADRLRERL
MUL_4299|M.ulcerans_Agy99         EFFDLVWRLMRFDKHGPLDLVLYDDNREEPRKWARNLIREMSADRLRERL
Rv0193c|M.tuberculosis_H37Rv      EFFDLIWRLMRFDKHGPLDLILYHDNREEPRKWARNLIREMSADRLYERL
Mb0199c|M.bovis_AF2122/97         EFFDLIWRLMRFDKHGPLDLILYHDNREEPRKWARNLIREMSADRLYERL
                                  *****:**************:**.********************** ***

MMAR_5224|M.marinum_M             SGWSADLGHHRPADCLRPLQVHALVSEVLRTLPLDGNQTPPADWDNDMLG
MUL_4299|M.ulcerans_Agy99         SGWSADLGHHRPADCLRPLQVHALVSEVPRTLPLDGNQTPPADWDNDMLG
Rv0193c|M.tuberculosis_H37Rv      LGWLADIQQPRPADCLRPLQIHALISEVLKTLPLDEDQDPPADWHFDLLG
Mb0199c|M.bovis_AF2122/97         LGWLADIQQPRPADCLRPLQIHALISEVLKTLPLDEDQDPPADWHFDLLG
                                   ** **: : **********:***:*** :***** :* *****. *:**

MMAR_5224|M.marinum_M             MSPAAAARSVRQLLEDIAEAVLRCEDMPAYLSTSLFAFWIVDSAYSLDGR
MUL_4299|M.ulcerans_Agy99         MSPAAAARSVRQLLEDIAEAVLRCEDMPAYLSTSLFAFWIVDSAYSLDGR
Rv0193c|M.tuberculosis_H37Rv      MSHAEAARSVKHLLEDVAEALLRCEDMAAYLSTSLFAFWAVDAAYSLDGR
Mb0199c|M.bovis_AF2122/97         MSHAEAARSVKHLLEDVAEALLRCEDMAAYLSTSLFAFWAVDAAYSLDGR
                                  ** * *****::****:***:******.*********** **:*******

MMAR_5224|M.marinum_M             RNLVVQDCTRRLLRHYVMLALTAMPEAPVA
MUL_4299|M.ulcerans_Agy99         RNLVVQDCTRRLLRHYVMLALTAMLEAPVA
Rv0193c|M.tuberculosis_H37Rv      RNLVVKDCARRLLRHYTMLSLTCFQ-----
Mb0199c|M.bovis_AF2122/97         RNLVVKDCARRLLRHYTMLSLTCFQ-----
                                  *****:**:*******.**:**.: