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ARHFSETLVALAGGRPEVLAVVPGARTKFVAMGAVVLATAALAALSAGFAANMALNATLPVAVTIGVLWG VVILLIDRALVVGMGNQPALGRNLAMAAPRVVLALILGTVISTPLTLHIFHPEIDTEIKTIQREEADDFN KRLKADDRFIVIPSLEQQVADAKARVVSDGGADPVVKDKQAAYDAAYAEYLRLQQSAQCELDGTCGTGRA GVAEAYRNAQAAADRQRAVADAARNERDAAAAASKGQAEKDLADTEEQLDELVRQRDQLQAEFDARNTDN SGLLIRLDALHRIGERDALLGWAHLLLWAMFTCIELLPVLIKLLMNMGASSAYDRVQQNQDNGDADVFDD QMLAWKDLQTARAQVGLDIETDRLEREKQRGIDINKTVFEVEADVIKDTLAVWSAQARMRARDQLAAYES ELAQQQPAAAPTVRLHTTAGSAPATTAGAPQPARNGASTNRYLQTGQLPDGGML*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5988 | - | - | 100% (475) | hypothetical protein Mvan_5988 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1808c | - | 2e-08 | 24.18% (455) | integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1779c | - | 2e-08 | 24.18% (455) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2942 | - | 2e-08 | 24.46% (466) | hypothetical protein MAV_2942 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1808c|M.bovis_AF2122/97 MCAHEYAEQRSAVSGIEGLLTWLGGGHWRELGERHERSTHAVAGVIVAVG
Rv1779c|M.tuberculosis_H37Rv MCAHEYAEQRSAVSGIEGLLTWLGGGHWRELGERHERSTHAVAGVIVAVG
MAV_2942|M.avium_104 ------------------MLIWLGGGEAGEPGERHERSAHAVAGAVVLLG
Mvan_5988|M.vanbaalenii_PYR-1 ----------MARHFSETLVALAGGRPEVLAVVPGARTKFVAMGAVVLAT
:: ** *: ... *.:*
Mb1808c|M.bovis_AF2122/97 AALAGLLASLAVSEAAQGPISSPIGAASLALVLGLLVG-AVTRGTASGPA
Rv1779c|M.tuberculosis_H37Rv AALAGLLASLAVSEAAQGPISSPIGAASLALVLGLLVG-AVTRGTASGPA
MAV_2942|M.avium_104 SALAWLVAGLAA--AGRWPLPALVPAT---LVFGLLVG-AIVRGTAA-PA
Mvan_5988|M.vanbaalenii_PYR-1 AALAALSAGFAANMALNATLPVAVTIGVLWGVVILLIDRALVVGMGNQPA
:*** * *.:*. * . .:. : *. **:. *:. * . **
Mb1808c|M.bovis_AF2122/97 RGR--AGVTGRASVAVAVGFVVGELAALVMFSGAIDRRLDEQAMHSADAT
Rv1779c|M.tuberculosis_H37Rv RGR--AGVTGRASVAVAVGFVVGELAALVMFSGAIDRRLDEQAMHSADAT
MAV_2942|M.avium_104 AGA--NRPVARGAVAAAVGVVVGELAALVILSGPIDQRLDEQASRTADSA
Mvan_5988|M.vanbaalenii_PYR-1 LGRNLAMAAPRVVLALILGTVISTPLTLHIFHPEIDTEIKTIQREEADDF
* . * :* :* *:. :* :: ** .:. . **
Mb1808c|M.bovis_AF2122/97 PAAVQASASLQQARNARTALDSAVERARGRLDDALVVARCEYHPTPACPQ
Rv1779c|M.tuberculosis_H37Rv PAAVQASASLQQARNARTALDSAVERARGRLDDALVVARCEYHPTPACPQ
MAV_2942|M.avium_104 PAVVTASATLRQAEEARAALDGAVAQARDRQDRALVVARCEYHPTPGCPQ
Mvan_5988|M.vanbaalenii_PYR-1 NKRLKADDRFIVIP----SLEQQVADAKAR-----VVSDGGADPVVKDKQ
: *. : :*: * *: * **: .*. *
Mb1808c|M.bovis_AF2122/97 TRITGVPGRGPETRTANQLLADAQRELDNALAARDHQAPALDAKMAHDEQ
Rv1779c|M.tuberculosis_H37Rv TRITGVPGRGPETRTANQLLADAQRELDNALAARDHQAPALDAKMAHDEQ
MAV_2942|M.avium_104 TRITGVPGPGPETRTANELLADAQRELDEALAARDSRAPELDAAVSRAQR
Mvan_5988|M.vanbaalenii_PYR-1 AAYDAAYAEYLRLQQSAQCELDGTCGTGRAGVAEAYRNAQAAADRQRAVA
: .. . . : : : *. ..* .*. : . * :
Mb1808c|M.bovis_AF2122/97 ALAEVRQAVVADAGRGLGSRWVAMNDLTLASAGALTARMLAIAFFALLYL
Rv1779c|M.tuberculosis_H37Rv ALAEVRQAVVADAGRGLGSRWVAMNDLTLASAGALTARMLAIAFFALLYL
MAV_2942|M.avium_104 AVADARRAAMADAGRGPGARWIAMNDVTAGNAGALTLRLLTIGGCVLLYL
Mvan_5988|M.vanbaalenii_PYR-1 DAARNERDAAAAASKGQAEKDLADTEEQLD---------------ELVRQ
* .: . * *.:* . : :* .: *:
Mb1808c|M.bovis_AF2122/97 LPLILRLWRGDTTHDRHAAARAERERAELEADTAIAIKRAEVRRAAEIMW
Rv1779c|M.tuberculosis_H37Rv LPLILRLWRGDTTHDRHAAARAERERAELEADTAIAIKRAEVRRAAEIMW
MAV_2942|M.avium_104 TPLILGLWRGETSHDRRAAARARRERAELDADTAIAIKRAEVRREAEIMW
Mvan_5988|M.vanbaalenii_PYR-1 RDQLQAEFDARNTDNSGLLIRLDALHRIGERDALLGWAHLLLWAMFTCIE
: : . .:.: * : : *: :. : : :
Mb1808c|M.bovis_AF2122/97 AEHQLTQTRLAIEAQAEIDREQQRRRVVEALEGP---------VRASSER
Rv1779c|M.tuberculosis_H37Rv AEHQLTQTRLAIEAQAEIDREQQRRRVVEALEGP---------VRASSER
MAV_2942|M.avium_104 AEHQLTQSRLAIEAQTEIDREHQRRRVLDAVADPPSPRAFEPTSELTSEL
Mvan_5988|M.vanbaalenii_PYR-1 LLPVLIKLLMNMGASSAYDRVQQNQ-----------------------DN
* : : : *.: ** :*.: :
Mb1808c|M.bovis_AF2122/97 TLQPVEDEVYLPIAAETEAASRTVAQLPAGAAHHRPGIAKNLPAQVQPEG
Rv1779c|M.tuberculosis_H37Rv TLQPVEDEVYLPIAAETEAASRTVAQLPAGAAHHRPGIAKNLPAQVQPEG
MAV_2942|M.avium_104 TSEPARDDVYLPIAAEAEAASRAITQAPQPRVECDPGPQQ-LPSSPPPND
Mvan_5988|M.vanbaalenii_PYR-1 GDADVFDDQMLAWKDLQTARAQVGLDIETDRLEREKQRGIDINKTVF---
. *: *. * ::. : . :
Mb1808c|M.bovis_AF2122/97 AVEPREKRATPVIRSIPDATKAAARWIRPLVPPFVARMLDNT----TAPL
Rv1779c|M.tuberculosis_H37Rv AVEPREKRATPVIRSIPDATKAAARWIRPLVPPFVARMLDNT----TAPL
MAV_2942|M.avium_104 AVE--QDWSTPLIPSIPDATKAAARWIRPLVPPLVARMMDTTTHRLTHPL
Mvan_5988|M.vanbaalenii_PYR-1 -----EVEADVIKDTLAVWSAQARMRARDQLAAYESELAQQQ--------
: : : ::. : * * :.. :.: :
Mb1808c|M.bovis_AF2122/97 RTARQVFE----EVEEIAFSFKRTHKVTVNAEG-----SDPNDQPPLESH
Rv1779c|M.tuberculosis_H37Rv RTARQVFE----EVEEIAFSFKRTHKVTVNAEG-----SDPNDQPPLESH
MAV_2942|M.avium_104 RTARQVFEGVVEETEEITFALRRTRKVTVNSQATQTASADPTEDTESRTE
Mvan_5988|M.vanbaalenii_PYR-1 ----------------------------------------PAAAPTVRLH
* . . .
Mb1808c|M.bovis_AF2122/97 SPAAP---AESNPIASSDSARRSRLATNDDHPPLAQVPPRDLASLSVGST
Rv1779c|M.tuberculosis_H37Rv SPAAP---AESNPIASSDSARRSRLATNDDHPPLAQVPPRDLASLSVGST
MAV_2942|M.avium_104 SRAAGPDFVTSTPQQPGPRAHR-RMTGRDARSSLPRSSAPDAGKLSVPSA
Mvan_5988|M.vanbaalenii_PYR-1 TTAGS-------APATTAGAPQPARNGASTNRYLQTGQLPDGGML-----
: *. . . * : . . * * . *
Mb1808c|M.bovis_AF2122/97 G----ELTQREGPHELRSPDGPRQLPPPR
Rv1779c|M.tuberculosis_H37Rv G----ELTQREGPHELRSPDGPRQLPPPR
MAV_2942|M.avium_104 ADDRAELTQRDGPAELEPPDGPRQLPPPH
Mvan_5988|M.vanbaalenii_PYR-1 -----------------------------