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GRRNRERRAAKKKQRRRPAAEREHSRSDTGPSRAQILEGLVIALSTAADLPGPGRAAELLEQYRGYEREL DIAADLVVHEAIRAAWERGWSPTDLHEIARRRVDAPVVRYLDAAIVLESQRYSAPTLHPRWSAELAEISA AAGSSATAPQMWNWAASHSTGEHAVITIVLQLLHLLGRIPKIQPVLPLPGEHRQAPGGAEGVDEKMLARV RALLAKAEATEYPDEAEALSAKAQALMVRHSWREAVADHDRGRAAVAAARRIWIGNPYVAAKVALVQAVA QANRCRTVWIKDLGCVVTVGSETDLDLVELLATSLLVQASRAMLVAGRHHGVRGQTRTKSFRLSFLVAYA ARIGERLSAASSSATAELQRDDRLLPVLAARNRAADETFTRLFPATVASPLVAYDPAGTGAGRAAADTAM LDVRDSIAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5887 | - | - | 100% (430) | hypothetical protein Mvan_5887 |
| M. vanbaalenii PYR-1 | Mvan_0152 | - | 1e-16 | 32.79% (244) | hypothetical protein Mvan_0152 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0190 | - | 8e-15 | 35.23% (193) | hypothetical protein Mb0190 |
| M. gilvum PYR-GCK | Mflv_0516 | - | 4e-16 | 35.42% (192) | hypothetical protein Mflv_0516 |
| M. tuberculosis H37Rv | Rv0184 | - | 8e-15 | 35.23% (193) | hypothetical protein Rv0184 |
| M. leprae Br4923 | MLBr_02604 | - | 2e-11 | 34.13% (167) | hypothetical protein MLBr_02604 |
| M. abscessus ATCC 19977 | MAB_4550c | - | 2e-12 | 35.00% (180) | hypothetical protein MAB_4550c |
| M. marinum M | MMAR_0428 | - | 2e-13 | 34.43% (183) | hypothetical protein MMAR_0428 |
| M. avium 104 | MAV_4996 | - | 7e-16 | 36.07% (183) | hypothetical protein MAV_4996 |
| M. smegmatis MC2 155 | MSMEG_1225 | - | 1e-114 | 53.09% (437) | hypothetical protein MSMEG_1225 |
| M. thermoresistible (build 8) | TH_0985 | - | 3e-16 | 31.56% (244) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1078 | - | 1e-13 | 33.88% (183) | hypothetical protein MUL_1078 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0428|M.marinum_M --------------------------------------------------
MUL_1078|M.ulcerans_Agy99 --------------------------------------------------
Mb0190|M.bovis_AF2122/97 --------------------------------------------------
Rv0184|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4996|M.avium_104 --------------------------------------------------
MLBr_02604|M.leprae_Br4923 --------------------------------------------------
MAB_4550c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0985|M.thermoresistible__bu --------------------------------------------------
Mflv_0516|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5887|M.vanbaalenii_PYR-1 MGRRNRERRAAKKKQRRRPAAEREHSRSDTGPSRAQILEGLVIALSTAAD
MSMEG_1225|M.smegmatis_MC2_155 MSRRNRQKRAAKQKDRRRASSQQGRWNTAPEYDRVAVLDHLIARLHHCAM
MMAR_0428|M.marinum_M --------------------------------------------------
MUL_1078|M.ulcerans_Agy99 --------------------------------------------------
Mb0190|M.bovis_AF2122/97 --------------------------------------------------
Rv0184|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4996|M.avium_104 --------------------------------------------------
MLBr_02604|M.leprae_Br4923 --------------------------------------------------
MAB_4550c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0985|M.thermoresistible__bu --------------------------------------------------
Mflv_0516|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5887|M.vanbaalenii_PYR-1 LP---GPGRAAELLEQYRGYERELDIAADLVVHEAIRAAWERGWSPTDLH
MSMEG_1225|M.smegmatis_MC2_155 CPDHDAESHATELLDECRDWAHDLDVAADGAMAVAIGGAWQAGWAPNDLH
MMAR_0428|M.marinum_M --------------------------------------------------
MUL_1078|M.ulcerans_Agy99 --------------------------------------------------
Mb0190|M.bovis_AF2122/97 --------------------------------------------------
Rv0184|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4996|M.avium_104 --------------------------------------------------
MLBr_02604|M.leprae_Br4923 --------------------------------------------------
MAB_4550c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0985|M.thermoresistible__bu --------------------------------------------------
Mflv_0516|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5887|M.vanbaalenii_PYR-1 EIARRRVDAPVVRYLDAAIVLESQRYSAPTLHPRWSAELAEISAAAGSSA
MSMEG_1225|M.smegmatis_MC2_155 EFARRRLDASSAGYLAEAIVLESRQYASTALHPRWRAEVAALSAGG--IP
MMAR_0428|M.marinum_M --------------------------------------------------
MUL_1078|M.ulcerans_Agy99 --------------------------------------------------
Mb0190|M.bovis_AF2122/97 --------------------------------------------------
Rv0184|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4996|M.avium_104 --------------------------------------------------
MLBr_02604|M.leprae_Br4923 --------------------------------------------------
MAB_4550c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0985|M.thermoresistible__bu --------------------------------------------------
Mflv_0516|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5887|M.vanbaalenii_PYR-1 TAPQMWNWAASHSTGEHAVITIVLQLLHLLGRIPKIQPVLPLPG-EHRQA
MSMEG_1225|M.smegmatis_MC2_155 DAPQMWGWASRQGVHHRTALTVVLKVLRFLGTLPILEPLLPLPGAAQHVA
MMAR_0428|M.marinum_M -----MTDDKMLARIAALLRQAEGTDNAHEADAFMSAAQRLATAASIDLA
MUL_1078|M.ulcerans_Agy99 -----MTDDKMLARIAALLRQAEGTDNAHEADAFMSAAQRLATAASIDLA
Mb0190|M.bovis_AF2122/97 -----MTNDKMLARIAALLRQAEGTDNPHEADAFMSTAQRLATAASIDLA
Rv0184|M.tuberculosis_H37Rv -----MTNDKMLARIAALLRQAEGTDNPHEADAFMSTAQRLATAASIDLA
MAV_4996|M.avium_104 -----MSDDKMLARIAALLRQAEGTDNSHEADAFMSAAQRLATAASIDLA
MLBr_02604|M.leprae_Br4923 -----MTDNKMLARIAALLRQAEGTDNAHEADAFMATAQRLATAASIDLA
MAB_4550c|M.abscessus_ATCC_199 -----MTEDKQLSRIAALLRQAEGTDNTHEAEAFMAAAQRLATATSIDLA
TH_0985|M.thermoresistible__bu -----MSDDKMLSRIAALLRQAEGTDNPHEAEAFMAAAQRLATATSIDLA
Mflv_0516|M.gilvum_PYR-GCK ----MSTDEKMLGRIAALLRQAEGTDNAHEAEAFMAAAQRLATATSIDLA
Mvan_5887|M.vanbaalenii_PYR-1 PGGAEGVDEKMLARVRALLAKAEATEYPDEAEALSAKAQALMVRHSWREA
MSMEG_1225|M.smegmatis_MC2_155 SVAANEADAKVLSRVRGLLAKAEATEFTEEAEALSAKAQELMSRYSLHHA
: * *.*: .** :**.*: ..**:*: : ** * * *
MMAR_0428|M.marinum_M VARSHSAHRSAASAPTQRTITIGTAGTRGLRTYAQLFVLIGAANDVRCDI
MUL_1078|M.ulcerans_Agy99 VARSHSAHRSAASVPTQRTITIGTAGTRGLRTYAQLFVLIGAANDVRCDI
Mb0190|M.bovis_AF2122/97 VARSHAGNRSPAQAPTQRTITIGAAGTRGLRTYVQLFVLIAAANDVRCDV
Rv0184|M.tuberculosis_H37Rv VARSHAGNRSPAQAPTQRTITIGAAGTRGLRTYVQLFVLIAAANDVRCDV
MAV_4996|M.avium_104 VARSHSAQRSAAQAPTQRTITIGAAGSKGLRTYVQLFVLIAAANDVRCDV
MLBr_02604|M.leprae_Br4923 VARSHVANRSTAQAPTQRTITIGTAGTRGLRTYVQLFVLIAAANDVRCDV
MAB_4550c|M.abscessus_ATCC_199 VARAHSAKRDAQARPTQRTITIGEAGTRGLRTYVNLFALIAGANDVTCDV
TH_0985|M.thermoresistible__bu VARAHSAERTKAQMPVQRTITIGEAGTKGLRTYVQLFVLIAAANDVKCDV
Mflv_0516|M.gilvum_PYR-GCK VARSHGDKRTRAQTPVQRTITIGEPGARGLRTYVQLFVVIAAANDVKCDV
Mvan_5887|M.vanbaalenii_PYR-1 VADHD---RGRAAVAAARRIWIGNP---YVAAKVALVQAVAQANRCRTVW
MSMEG_1225|M.smegmatis_MC2_155 IRDHQ---RSDAMEAVARRIWIDNP---YVVAKSALVQSVATANRCRMVC
: . * .. * * *. . : : *. :. **
MMAR_0428|M.marinum_M ATNSTFLYAYGFTEDIDATHALYASLVVQMVRASDGYLATGAHR-PTPTI
MUL_1078|M.ulcerans_Agy99 ATNSTFLYAYGFTEDIDATHALYASLVVQMVRASDGYLATGAHR-PTPTI
Mb0190|M.bovis_AF2122/97 ASNSTFVYAYGFAEDIDTSHALYASLVVQMVRASDAYLASGAHR-PTPTI
Rv0184|M.tuberculosis_H37Rv ASNSTFVYAYGFAEDIDTSHALYASLVVQMVRASDAYLASGAHR-PTPTI
MAV_4996|M.avium_104 ASNSTFVYAYGFAEDIDASHALYASLVVQMVRASDAYLASGAHR-PTPTI
MLBr_02604|M.leprae_Br4923 ASNSTFLYAYGFAEDIDATHALYASLVVQMVRESDAYLASGAYR-PTPTI
MAB_4550c|M.abscessus_ATCC_199 ASNSTYVYAYGFAEDIDAVHALYASLVVQMVRASDAYISSGAHR-PTPTI
TH_0985|M.thermoresistible__bu ASNSTFVYAYGFPEDIDATHALYASLVTQMVKASEAYIASGAHR-PTPTI
Mflv_0516|M.gilvum_PYR-GCK ASNSTFVYAYGFDEDIDASHTLYTSLVMQMVRASTEYISSGAHK-PTPTI
Mvan_5887|M.vanbaalenii_PYR-1 IKDLGCVVTVGSETDLDLVELLATSLLVQASRAMLVAGRHHGVRGQTRTK
MSMEG_1225|M.smegmatis_MC2_155 AEKIGFVAVIGADCDVDFVELLSTSLLVQANRAMLAAGRGTNGR-QTRTR
. : . * *:* . * :**: * : : * *
MMAR_0428|M.marinum_M TARLNFQLAFGARVGQRLAEAREQAKTEVAMDRSRAPGTEIALRDKELEL
MUL_1078|M.ulcerans_Agy99 TARLNFQLAFGARVGQRLAEAREQAKTEVAMDRSRAPGTEIALRDKELEL
Mb0190|M.bovis_AF2122/97 TARLNFQLAFGARVGQRLADAREQTRQEATKDRDRPPGTAIALRDKDIEL
Rv0184|M.tuberculosis_H37Rv TARLNFQLAFGARVGQRLADAREQTRQEATKDRDRPPGTAIALRDKDIEL
MAV_4996|M.avium_104 TARLNFQLAFGARVGQRLAEARDQARQEATKDRRRTPGTAIALRDKEIEL
MLBr_02604|M.leprae_Br4923 TARLNFQLGFGMRVGQRLTEARDHIRSAVTEAWDRPTATAIALRDKEIEL
MAB_4550c|M.abscessus_ATCC_199 TARLNFQLAFGTRVGQRLTDARQEARAEAVKTEKRGTGTELVLRDKEIEL
TH_0985|M.thermoresistible__bu TARINFQLAFGARIGQRLAQAREEAQQAATEDRDTAPGTAIALRDKDLEL
Mflv_0516|M.gilvum_PYR-GCK TARLNFQLAFGARVGQRLAEAREQAQQEAKSGPSAIPGTAIALRNKDLEL
Mvan_5887|M.vanbaalenii_PYR-1 SFRLSFLVAYAARIGERLSAASSSATAELQRDDRLLPVLAARNRAADETF
MSMEG_1225|M.smegmatis_MC2_155 SFRQSFLLSYAARIGERLTATSATVATEMDR-DALLPVLAARSQATDDLT
: * .* :.:. *:*:**: : . : :
MMAR_0428|M.marinum_M RDHYRSASQARGTWRATRASAGYSSAARRAGDRAGRQARLGKSPELPGAR
MUL_1078|M.ulcerans_Agy99 RDHYRSASRARGTWRATRASAGYSSAARRAGDRAGRQARLGKSPELPGAR
Mb0190|M.bovis_AF2122/97 HEYYRRSSKARGAWRASRATAGYSSAARRAGDRAGRQARLGNNPELPGAR
Rv0184|M.tuberculosis_H37Rv HEYYRRSSKARGAWRASRATAGYSSAARRAGDRAGRQARLGNNPELPGAR
MAV_4996|M.avium_104 VDFYRSASKARGTWQASRASAGYSSAARRAGDRAGRRARLGSSPELPGAR
MLBr_02604|M.leprae_Br4923 IDYYRSASKARGTWQAARASAGYSSAARNAGDQAGRRAWIDNSTELPGAR
MAB_4550c|M.abscessus_ATCC_199 RDFYKGTSTARGRWRAVSAQAGYSSHARRAGDRAGRRARLGASPELAGAR
TH_0985|M.thermoresistible__bu QDFYRQTSKARGTWRPTSATAGYSSAARRAGDRAGRRARLGPSPELAGPR
Mflv_0516|M.gilvum_PYR-GCK KDYYRKASKARGTWRATSATAGYSSDARRAGDRAGRRARLGGDTELTGAR
Mvan_5887|M.vanbaalenii_PYR-1 TRLFPAT--------VASPLVAYDPAGTGAGRAAADTAMLDVRDSIAG--
MSMEG_1225|M.smegmatis_MC2_155 DRLFPTT--------VPRELSVSNGAGWLAGRTAADLALLDVHRPIAG--
: : . . ** *. * :. :.*
MMAR_0428|M.marinum_M TALDR-
MUL_1078|M.ulcerans_Agy99 TALDR-
Mb0190|M.bovis_AF2122/97 AALGR-
Rv0184|M.tuberculosis_H37Rv AALGR-
MAV_4996|M.avium_104 SALSG-
MLBr_02604|M.leprae_Br4923 AALGR-
MAB_4550c|M.abscessus_ATCC_199 AALDKN
TH_0985|M.thermoresistible__bu AALDK-
Mflv_0516|M.gilvum_PYR-GCK SALER-
Mvan_5887|M.vanbaalenii_PYR-1 ------
MSMEG_1225|M.smegmatis_MC2_155 ------