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M. vanbaalenii PYR-1 Mvan_5561 (-)

TTPAGRSSGTVVAGIDVGNHTTEIVLARVRDGAVTTLAHGQAPTRGRKGSAESLQGAAALLHRIEVDAGC
RAEELLLSALRPVDTATAPIPPAYSPTSPVRSLRRPDASTPAGTGYGVGQHVRLCDLNAGVVDEPVVISV
DETTDFEVAAREISLAVARGWQVVGVVAAQDDAVLIRNRIPIDVPVVDEADLTGLEPGALVAVEVVEEGR
AYRAMADPIALSAALHLPAGSLVEVAEFCRELADSAAIAVTPRTEAPLPPAPDDDYVDVRVDGALVRYTP
AEAHGVLRRSVPGCVNAIRLRSVPTAASGLSVHDAFFTDLGSIDNGAWLRRGVADAQGTVVALLAAEEAD
DAAASLSELTGRPARTLSSEPEAAAWGARTTPGLPPGSMVCDIGGGTVDLIGADGTVVAAGAGESITVAV
ARVLGIPHALAETVKRTPAVRVEGPHVAHEEDGRRVFLDSPASSDAIGRLCTRGSAGLVPFSDRLAAEEW
RSLRLAIKQETVAANIARCLTAFGESPTALVLAGGGALDDELMRTVGEALRSVPIVVGRADVDGVHGPRF
AVARGLIAMYAADQLSGDDSAD*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_5561	-	-	100% (583)	hypothetical protein Mvan_5561

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_1247	-	0.0	81.49% (562)	hypothetical protein Mflv_1247
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_6318	-	0.0	73.64% (569)	putative diol dehydratase reactivation protein
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_5561|M.vanbaalenii_PYR-1       MTTPAGRSSGTVVAGIDVGNHTTEIVLARVRDGAVTTLAHGQAPTRGRKG
Mflv_1247|M.gilvum_PYR-GCK          MTP-------TVVAGVDIGNHTTEILLAQVHGGTVTTVAHGQAPTRGRKG
MSMEG_6318|M.smegmatis_MC2_155      MIP------AGLIAGIDVGNHTTEIVLARVTDGTVHPVGHGQAPTRGRKG
                                    * .        ::**:*:*******:**:* .*:* .:.***********

Mvan_5561|M.vanbaalenii_PYR-1       SAESLQGAAALLHRIEVDAGCRAEELLLSALRPVDTATAPIPPAYSPTSP
Mflv_1247|M.gilvum_PYR-GCK          SRESVEGAAALLHRVEVDAGRRADELLLAALRPVDTATAPIPPAYSPSAP
MSMEG_6318|M.smegmatis_MC2_155      SRESLEGAAALLHRLEVDLQVRAEMLVLSAIRPVDTETAPLAPATVPHAP
                                    * **::********:***   **: *:*:*:***** ***:.**  * :*

Mvan_5561|M.vanbaalenii_PYR-1       VRSLRRPDASTPAGTGYGVGQHVRLCDLNAGVVDEPVVISVDETTDFEVA
Mflv_1247|M.gilvum_PYR-GCK          VRSLRRPDASTPAGAGHAVGLHVPLTALQHGVSGGPVVVSVDETTDFEVA
MSMEG_6318|M.smegmatis_MC2_155      VRSLRRPDASTPAGSGYAVGRHVPLAALKHDDRHDAVIVSVDATTDFEDA
                                    **************:*:.** ** *  *: .    .*::*** ***** *

Mvan_5561|M.vanbaalenii_PYR-1       AREISLAVARGWQVVGVVAAQDDAVLIRNRIPIDVPVVDEADLTGLEPGA
Mflv_1247|M.gilvum_PYR-GCK          AQQISAAVDRGWQVVGVIAAQDDAVLIRNRIPVDVPVVDEVDLTGLAPGA
MSMEG_6318|M.smegmatis_MC2_155      AAAITDAVGKGANVVGVLAAQDDAVLIRNRIPIDVPVVDEVDLDGLAPDV
                                    *  *: ** :* :****:**************:*******.** ** *..

Mvan_5561|M.vanbaalenii_PYR-1       LVAVEVVEEGRAYRAMADPIALSAALHLPAGSLVEVAEFCRELADSAAIA
Mflv_1247|M.gilvum_PYR-GCK          RVALEVVEQGRSYRAMADPIALSAALELPAGSLVDVAEFCRELADTAAIA
MSMEG_6318|M.smegmatis_MC2_155      LVAVEVVAEGRAYRALADPIAVCAALQLGHENLRDIAEFTRELADSPAIA
                                     **:*** :**:***:*****:.***.*   .* ::*** *****:.***

Mvan_5561|M.vanbaalenii_PYR-1       VTPRTEAPLPPAPDDDYVDVRVDGALVRYTPAEAHGVLRRSVPGCVNAIR
Mflv_1247|M.gilvum_PYR-GCK          VTPRTDTHRSPPPDDDYVDLRDGGSVVRYSPAEANPVMRRVIPGSVREVR
MSMEG_6318|M.smegmatis_MC2_155      LTPRTRPPQPPAPDDDYVEFARDGEQVRYPPAQAHTILRREPPGSVVRIR
                                    :**** .  .*.******:.  .*  ***.**:*: ::**  **.*  :*

Mvan_5561|M.vanbaalenii_PYR-1       LRSVPTAASGLSVHDAFFTDLGSIDNGAWLRRGVADAQGTVVALLAAEEA
Mflv_1247|M.gilvum_PYR-GCK          LKAVPSAAGGLAVHDAFFTDLSGIDNGAWLRRGVADTQGTVVALLAAEEA
MSMEG_6318|M.smegmatis_MC2_155      LRSVPTADHEMAVDDAFFTDLAALDNGTWLRRGVADASGTVVALLAADHV
                                    *::**:*   ::*.*******..:***:********:.*********:..

Mvan_5561|M.vanbaalenii_PYR-1       DDAAASLSELTGRPARTLSSEPEAAAWGARTTPGLPPGSMVCDIGGGTVD
Mflv_1247|M.gilvum_PYR-GCK          ADAADTLGTLTGRRARTLSSEPEAAAWGARTTPGIPADTVICDIGGGTVD
MSMEG_6318|M.smegmatis_MC2_155      ADAAATLAELTGRPARTLASEPEAAARGARTTPGLPPDSVVCDIGGGTID
                                     *** :*. **** ****:******* *******:*..:::*******:*

Mvan_5561|M.vanbaalenii_PYR-1       LIGADGTVVAAGAGESITVAVARVLGIPHALAETVKRTPAVRVEGPHVAH
Mflv_1247|M.gilvum_PYR-GCK          LIGIDRAVVAAGAGESITVAVARVLGIPRALAEKVKRTPAVRVEGPHIAH
MSMEG_6318|M.smegmatis_MC2_155      LVGAERTVTAAGAGETITVAVAKMLGIPRALAERVKRTPAIRVEGPHVAH
                                    *:* : :*.******:******::****:**** ******:******:**

Mvan_5561|M.vanbaalenii_PYR-1       EEDGRRVFLDSPASSDAIGRLCTRGSAGLVPFSDRLAAEEWRSLRLAIKQ
Mflv_1247|M.gilvum_PYR-GCK          EEDGRRVFLDSPASADAIGRLCTRGGAGLVPFSDRLAAEEWRSLRLAVKQ
MSMEG_6318|M.smegmatis_MC2_155      EEDGRRLFLDAPAPAEAIGRLCTRGTAGLVPFSSRLAAEEWRSLRLAIKQ
                                    ******:***:**.::********* *******.*************:**

Mvan_5561|M.vanbaalenii_PYR-1       ETVAANIARCLTAFGESPTALVLAGGGALDDELMRTVGEALRSVPIVVGR
Mflv_1247|M.gilvum_PYR-GCK          ETVAANIVRCLRAFEQPPAALVLAGGGALDDELMRTVGEALRSVPVVVGR
MSMEG_6318|M.smegmatis_MC2_155      ETVAANIARCMKAFEKPPTALVLAGGGALDDELLRTVGESLRTAGVVVGR
                                    *******.**: ** :.*:**************:*****:**:. :****

Mvan_5561|M.vanbaalenii_PYR-1       ADVDGVHGPRFAVARGLIAMYAADQLSGDDSAD-
Mflv_1247|M.gilvum_PYR-GCK          TDVDGVHGPRFAVARGLVAMYAQS----------
MSMEG_6318|M.smegmatis_MC2_155      ANIDGVHGPRFAVASGLVHLYAESAGERGAQEVS
                                    :::*********** **: :** .