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TATEAILALVDDRALSADIDRVVAAAGVRIVRATDPSSHRVWTGASAVLLDTAAAQRCAARGLPRRPRVL LISGDAPGPDEWEAAVAVGAQQVVTLPSGDHELMAELADATEAARHTGLRGPVVAVLAGRGGGGASVFAT AVAKVATEALLIDGDPWGGGLDLVLGSETEPGLRWPDLSLAGGRVGFSALRDALPTRHGVYVLSGSRALS GTHSSNDIDAAALGAVIDAGSRGGVTVVCDVARRPTPASETAVASADLVVLVTPADVRSCAAAAATAQWV AGGNPNAGVVVRGPSPGGLRSVDVARIVGLPVLASMRPQPGIDTLLERGGLRVRPHSPLARAAREVLAVL SQSPQLEAAAEAVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5422 | - | - | 100% (365) | hypothetical protein Mvan_5422 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3684c | - | 2e-97 | 53.31% (347) | hypothetical protein Mb3684c |
| M. gilvum PYR-GCK | Mflv_1383 | - | 1e-158 | 76.99% (365) | hypothetical protein Mflv_1383 |
| M. tuberculosis H37Rv | Rv3660c | - | 1e-98 | 53.60% (347) | hypothetical protein Rv3660c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0432 | - | 2e-83 | 47.63% (359) | hypothetical protein MAB_0432 |
| M. marinum M | MMAR_5148 | - | 1e-96 | 52.78% (360) | hypothetical protein MMAR_5148 |
| M. avium 104 | MAV_0470 | - | 2e-93 | 51.78% (338) | hypothetical protein MAV_0470 |
| M. smegmatis MC2 155 | MSMEG_6171 | - | 1e-109 | 63.89% (324) | hypothetical protein MSMEG_6171 |
| M. thermoresistible (build 8) | TH_2271 | - | 1e-67 | 57.55% (245) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4233 | - | 3e-86 | 51.68% (327) | hypothetical protein MUL_4233 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5422|M.vanbaalenii_PYR-1 -------MTATEAILALVDDRALSADIDRVVAAAGVRIVRATDPS--SHR
Mflv_1383|M.gilvum_PYR-GCK -------MDTAEGVLALVEDPTLNSHVERVAAAAGLRMVRTDDPS--SRR
MSMEG_6171|M.smegmatis_MC2_155 ------------------------------------------MPS--SRK
TH_2271|M.thermoresistible__bu --------------------------------------------------
MAB_0432|M.abscessus_ATCC_1997 -----MEANTGQPIVVAVGDRQLSNEIERIVAAAGKPLVLATDAGSISRQ
Mb3684c|M.bovis_AF2122/97 ----------------MLTDPGLRDELDRVAAAVGVRVVHLGGRHLVSRK
Rv3660c|M.tuberculosis_H37Rv ----------------MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRK
MMAR_5148|M.marinum_M MTKPLHTATDSAGVLSMLVDPKLRDELDRVAAAVGVRIVHGDGRKPVTRK
MUL_4233|M.ulcerans_Agy99 MTKPLHTATDSAGVLSMLVDPKLRDELDRVAAAVGVRIVHGDGRKPVTRK
MAV_0470|M.avium_104 ----------------MLAEPELRAELDRVAAAAGVRVVHAGDAAAVSRK
Mvan_5422|M.vanbaalenii_PYR-1 VWTGASAVLLDTAAAQRCAARGLPRRPRVLLISGDAPGPDEWEAAVAVGA
Mflv_1383|M.gilvum_PYR-GCK VWTGAAAVLVDGAAARRCAARGLPRRSRVLLISADAPGADDWEAAVAVGA
MSMEG_6171|M.smegmatis_MC2_155 AWLSAAAVLLDASAARRCADRGLPRRDRVLVIGCDEPGPADWQAAIAVGA
TH_2271|M.thermoresistible__bu --------------------------------------------------
MAB_0432|M.abscessus_ATCC_1997 AWTRAGAVVLDGADTSMAALAQLPRRSRVLLICRDEPTNEVWRRAVEVGA
Mb3684c|M.bovis_AF2122/97 TWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGA
Rv3660c|M.tuberculosis_H37Rv TWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGA
MMAR_5148|M.marinum_M AWSAAGAVVLDPAAARGLSQAALPRRAHVCLLTGAEAGTDTWATAVAIGA
MUL_4233|M.ulcerans_Agy99 AWSAAGAVVLDPAAARGLTQAALPRRAHVCLLTGAEAGTDTWVTAVAIGA
MAV_0470|M.avium_104 TWAAAAAVVLDAAAAARCGRWALPRRDHVTVLTAAEPATTTWAAAVRIGA
Mvan_5422|M.vanbaalenii_PYR-1 QQVVTLPSGDHELMAELADATEAAR---HTGLRGPVVAVLAGRGGGGASV
Mflv_1383|M.gilvum_PYR-GCK QQIVTLPAEDRDLMAALSDAAEAAR---DPRRRGPIVAVLAGRGGGGASV
MSMEG_6171|M.smegmatis_MC2_155 QHVVTLPRQDTDLVAALSVVDEGG------GHRGPVVAVVAAKGGAGASV
TH_2271|M.thermoresistible__bu -----VTDRDDSLRRELG-------------WTGP-----EERNXXXXSL
MAB_0432|M.abscessus_ATCC_1997 EQVLALPEDEATLVAALSAMPSTAS-----AGRAPVIVVVGGCGGAGASV
Mb3684c|M.bovis_AF2122/97 QHVLRMPEQEGELVRELAEAAESARDDGI---CGAVVAVIGGRGGAGASL
Rv3660c|M.tuberculosis_H37Rv QHVLRMPEQEGELVRELAEAAESARDDGI---CGAVVAVIGGRGGAGASL
MMAR_5148|M.marinum_M GAVLQMPEQEGELIRELAEAVEAARDEGLGGEVGQVIAVIGGSGGAGVSL
MUL_4233|M.ulcerans_Agy99 GAVLQMPEQEGELIRELAEAVEAARDEGLGGEVGQVISVIGGSGGAGVSL
MAV_0470|M.avium_104 ARVLRLPEHEADLVGELAEAAESSRDDGQ---RGHAVAVIGGCGGAGASL
:. : * *. . . *:
Mvan_5422|M.vanbaalenii_PYR-1 FATAVAKVAT-EALLIDGDPWGGGLDLVLGSETEPGLRWPDLSLAGGRVG
Mflv_1383|M.gilvum_PYR-GCK FATAVAQSAP-ESLLIDGDPWGGGLDLVLGSETEPGLRWPDLSLAGGRVG
MSMEG_6171|M.smegmatis_MC2_155 FAAALALSAP-GALLVDADPWSGGIDLVLGSEDQPGLRWADLALQGGRLG
TH_2271|M.thermoresistible__bu FAAALAKSAG-ETLLVDVDPCSGGLDLALGGECAPGLRWPDLSVQTGRLA
MAB_0432|M.abscessus_ATCC_1997 LCAAIGLRAPSGAMIVDADPYGGGMDLLLGWEDIPGLRWPDVDMRGGRVS
Mb3684c|M.bovis_AF2122/97 FAVALAQAAA-DALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLN
Rv3660c|M.tuberculosis_H37Rv FAVALAQAAA-DALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLN
MMAR_5148|M.marinum_M FAAALAQSAA-DALLVDLDPWGGGIDLLMGCENLPGLRWPDLSLQGGRLA
MUL_4233|M.ulcerans_Agy99 FAAALAQSAA-DALLVDLDPWGGGIDLLMGCENLPGLRWPGLSLQGGRLA
MAV_0470|M.avium_104 LAVALAQAAG-DALLVDLDPWGGGIELLLGGENTPGLRWPDLALQGGRLN
:..*:. * ::::* ** .**::* :* * *****..: : **:
Mvan_5422|M.vanbaalenii_PYR-1 FSALRDALPTRHGVYVLSGSRALSGTHSSNDIDAAALGAVIDAGSRGGVT
Mflv_1383|M.gilvum_PYR-GCK YAALRDALPRRHGVAVLSGSRVLSGDRSSNDIDPAPLGAVIDAGSRGGVT
MSMEG_6171|M.smegmatis_MC2_155 YGALRDALPRRGEISVLSGG------RAGVDITAAALHAVIDAGCRGATL
TH_2271|M.thermoresistible__bu YPALRDALPRCGDVSVLSAG------RGGADITSEALSAVIDAGSRAGVT
MAB_0432|M.abscessus_ATCC_1997 FDALRRALPHRRGLVVLSGD------RTGGGGNVETIAGVIDSAREAGVA
Mb3684c|M.bovis_AF2122/97 WSAVRAALPRPRGISVLSGT------RRGYELDAGPVDAVIDAGRRGGVT
Rv3660c|M.tuberculosis_H37Rv WSAVRAALPRPRGISVLSGT------RRGYELDAGPVDAVIDAGRRGGVT
MMAR_5148|M.marinum_M WSAVRDGLPRHRGISLLSGT------RRGQELDCGAVGALIDAGRRGAVT
MUL_4233|M.ulcerans_Agy99 WSAVRDGLPRHRGISLLSGT------RRGQELDCGAVGALIDAGRRGAVT
MAV_0470|M.avium_104 WAAVRDALPRHRGVSVLSGT------RRGHEVDAGPVHAVVDAGRRGAVS
: *:* .** : :**. : . .: .::*:. ....
Mvan_5422|M.vanbaalenii_PYR-1 VVCDVARRPTPASETAVASADLVVLVTPADVRSCAAAAATAQWVAGGNPN
Mflv_1383|M.gilvum_PYR-GCK VVCDVARRPGAAAETAVAAADLVVLVTPADLRSCAASAATAQWVTAANPN
MSMEG_6171|M.smegmatis_MC2_155 VVCDVPRRSTDAAEAALEAADLVVVVARADVRSCAAAAAAGSWIATCNPN
TH_2271|M.thermoresistible__bu VICDVPRHPGGVVETALHTADLAILVTVADVRSCAAAAVTARWVGGVNPN
MAB_0432|M.abscessus_ATCC_1997 VVVDLPRRLGASGVAALERADLVVVVTTAEVRACAASALVARAVRTTNPN
Mb3684c|M.bovis_AF2122/97 VVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPN
Rv3660c|M.tuberculosis_H37Rv VVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPN
MMAR_5148|M.marinum_M VVCDLPRRLTDAVQVALDRADLVVLVCPCDVRSCAATATIVPVLAAINPH
MUL_4233|M.ulcerans_Agy99 VVCDLPRRLTDAVQVALDRADLVVLVCPCDVRSCAATATIVPVLAAINPH
MAV_0470|M.avium_104 VICDLPRRFTDAAQAALGAADLVVVVSRCDVRACAATGALAPVLAAVNPN
*: *:.*: .*: ***.::* .::*:***:. : **:
Mvan_5422|M.vanbaalenii_PYR-1 AGVVVRGPSPGGLRSVDVARIVGLPVLASMRPQPGIDTLLERGGLRVRPH
Mflv_1383|M.gilvum_PYR-GCK TGVVVRGPAPGGLRPADVARIVGLPVLTAMRPQPGIESALERGGLRVRAR
MSMEG_6171|M.smegmatis_MC2_155 IGVVVRGPAPGGLRAAEVADIVDLPLLASMRPQPGLDEALERGGLRLTRR
TH_2271|M.thermoresistible__bu VALVVRGPAPGGLSPRDVARIVEVPLVAWMRPQPRLAETLELGGLRLRAR
MAB_0432|M.abscessus_ATCC_1997 VGVVVRGPAPSGLRAPEVAEIVGVPLIAAMRPEPNLASRLDKGGLRLSRR
Mb3684c|M.bovis_AF2122/97 LGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRR
Rv3660c|M.tuberculosis_H37Rv LGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRR
MMAR_5148|M.marinum_M LGLVVRGPSPGGLRAAEVADIAGVPLLASMRVQPRLVEQLEHGGLRLRRR
MUL_4233|M.ulcerans_Agy99 LGLVVRGPSPGGLRAAEVADIAGVPLLASMRVQPRLVE------------
MAV_0470|M.avium_104 VGLVVRGPSPGGLRAAEIAGITGLPLLAAIKAQPQLGAQVERVGLRLGRR
.:*****:*.** . ::* :. :*::: :: :* :
Mvan_5422|M.vanbaalenii_PYR-1 SPLARAAREVLAVLSQSPQLEAAAEAVA
Mflv_1383|M.gilvum_PYR-GCK SPLARAAREVLSVLGLNPHLDRTSETAA
MSMEG_6171|M.smegmatis_MC2_155 SPLATAARRVLGVLAQHPVREAA-----
TH_2271|M.thermoresistible__bu SPLAGAARRVLAVVQQHPVVDAA-----
MAB_0432|M.abscessus_ATCC_1997 SPLAAAAQSVLSLVSQDGKASAA-----
Mb3684c|M.bovis_AF2122/97 SVLASAARRVLGVLPRAGSGRHGRAA--
Rv3660c|M.tuberculosis_H37Rv SVLASAARRVLGVLPRAGSGRHGRAA--
MMAR_5148|M.marinum_M SPLAAAARRVLALLPNSTAVPGGRAA--
MUL_4233|M.ulcerans_Agy99 ----------------------------
MAV_0470|M.avium_104 SALAVAARQVLGVLPPAGARRKGKAA--