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VHLSWHVVTSPDSPDDIPEQFRIRQGKRDRLLAEGRDPYPVKVDRTHTLAELRAAYPDLPADTKTGQEVG VAGRVIFARNSGKLCFATLQEGDGTHLQAMISLDQVGQDSLDAWKADVDLGDIVFVHGEVISSRRGELSV LADSWQIASKALRPLPVAHKEMSEESRVRQRYVDLIVRPEARAIARQRVAVVRAVRNALERRGFLEVETP MLQTLAGGAAARPFVTHSNALDADLYLRIAPELFLKRCVVGGFDRVFELNRNFRNEGADSTHSPEFAMLE TYQAYGTYDDSALVTRQLIQEVADEAIGTRQVPLADGSVYDLDGEWDDIQMYPSLSEALGEEITPQTAVP RLWRIADGLGVEIPRDRGYGHGKLVEELWEFTVGDKLWAPTFVRDFPVETTPLTRPHRSIEGVTEKWDLY IRNFELATGYSELVDPIIQRERFEEQARAAAAGDDEAMALDEDFLAALEYGMPPTTGTGMGIDRLLMALT GLSIRETVLFPIVRRHGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5360 | lysS | - | 100% (509) | lysyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_3330 | lysS | e-118 | 47.59% (498) | lysyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_2615 | aspS | 6e-16 | 28.90% (263) | aspartyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3629c | lysS | 0.0 | 82.18% (505) | lysyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_1428 | lysS | 0.0 | 91.62% (501) | lysyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv3598c | lysS | 0.0 | 82.18% (505) | lysyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_00233 | lysS | 0.0 | 79.64% (496) | lysyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_0544 | - | 0.0 | 78.07% (497) | lysyl-tRNA synthetase (LysS) |
| M. marinum M | MMAR_5102 | lysS | 0.0 | 81.44% (501) | lysyl-tRNA synthetase 1 LysS |
| M. avium 104 | MAV_0554 | lysS | 0.0 | 84.51% (497) | lysyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_6094 | lysS | 0.0 | 87.42% (493) | lysyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_2348 | lysS | 0.0 | 84.34% (498) | LYSYL-TRNA SYNTHETASE 1 LYSS (LYSINE--TRNA LIGASE 1) (LYSRS |
| M. ulcerans Agy99 | MUL_4181 | lysS | 0.0 | 80.84% (501) | lysyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5360|M.vanbaalenii_PYR-1 MVHLSWHVVTSPD--SPDDIPEQFRIRQGKRDRLLAEGRDPYPVKVDRTH
Mflv_1428|M.gilvum_PYR-GCK --------MTSPD--SPDDIPEQFRIRQAKRERLLAEGREPYPVKVDRTH
MSMEG_6094|M.smegmatis_MC2_155 --MTPADRDDTSQ--PQADIPEQFRIRQEKRERLLAQGHDPYPVKVDRTH
MMAR_5102|M.marinum_M --------MSS----AESDIPEQFRIRRDKRARLLAEGYDPYPVAIERTH
MUL_4181|M.ulcerans_Agy99 --------MSS----AESNIPEQFRIRRDKRARLLAEGYDPYPVAIERTH
MLBr_00233|M.leprae_Br4923 --------MNADPLETDAALPEQFRIRRDKRARLLAEGRDPYPVAIERTH
Mb3629c|M.bovis_AF2122/97 --------MSAAD--TAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTH
Rv3598c|M.tuberculosis_H37Rv --------MSAAD--TAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTH
MAV_0554|M.avium_104 --------MSPAP---DADIPEQYRIRRDKRARLLAEGHDPYPVAVERTH
TH_2348|M.thermoresistible__bu --------VTPPE-SVDPDLPEQFRIRQAKRADLLAQGRQPYPVDVPRTH
MAB_0544|M.abscessus_ATCC_1997 --------MTDPD--AQTSLPEQFRIRQAKREKLLAEGVQPYPVEVPRTH
:***:***: ** ***:* :**** : ***
Mvan_5360|M.vanbaalenii_PYR-1 TLAELRAAYPDLPADTKTGQEVGVAGRVIFARNSGKLCFATLQEGDGTHL
Mflv_1428|M.gilvum_PYR-GCK TLAELRQAYPDLEPDTKTGLKVGVAGRVIFARNSGKLCFATLQEGDGAQL
MSMEG_6094|M.smegmatis_MC2_155 TLAELRRAHPDLAADTATGQIVGVSGRVVFARNSGKLCFATLQEGDGTQL
MMAR_5102|M.marinum_M TLAEIRATYADLPTDSATEDIVGVAGRVVFARNTGKLCFATLQDGDGTQL
MUL_4181|M.ulcerans_Agy99 TLAEIRATYADLPTDSATEDIVGVAGRVVFARNTGKLCFATLQDGDGTQL
MLBr_00233|M.leprae_Br4923 TLAEVRAAYPDLATDSATDDIVGIAGRVIFARNSGKLCFATLQDGDGTNL
Mb3629c|M.bovis_AF2122/97 TLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFATLQDGDGTQL
Rv3598c|M.tuberculosis_H37Rv TLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFATLQDGDGTQL
MAV_0554|M.avium_104 TLAQVRAAHPDLPVDTATDDVVGVAGRVIFARNSGKLCFATLQEGDGTTL
TH_2348|M.thermoresistible__bu TLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKLCFATLQEGDGTQL
MAB_0544|M.abscessus_ATCC_1997 SLKQIRDAYTDLETDTSTGDQVGVSGRVIFSRNTGKLCFATLQEGDGTSL
:* ::* ::.** *: * **::***:*:**:*********:***: *
Mvan_5360|M.vanbaalenii_PYR-1 QAMISLDQVGQDSLDAWKADVDLGDIVFVHGEVISSRRGELSVLADSWQI
Mflv_1428|M.gilvum_PYR-GCK QVMISFAEVGQESLDAWKADVDLGDIVFVHGEVISSRRGELSVLADSWQI
MSMEG_6094|M.smegmatis_MC2_155 QVMISLAQVGQEALDSWKSDVDLGDIVFVHGEVISSKRGELSVLADRWQM
MMAR_5102|M.marinum_M QAMISLDKVGRESLDRWKADVDIGDVVYVHGTVISSRRGELSVLADSWRM
MUL_4181|M.ulcerans_Agy99 QAMISLDEVGRESLDRWKADVDIGDVVYVHGTVISSRRGELSVLADSWRM
MLBr_00233|M.leprae_Br4923 QVMISLNKVGSETLDAWKVDVDLGDIVYVHGNVISSRSGELSVLADSWQM
Mb3629c|M.bovis_AF2122/97 QVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRI
Rv3598c|M.tuberculosis_H37Rv QVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRI
MAV_0554|M.avium_104 QVMVSLDKVGREALDAWKADVDLGDIVSVHGTLISSRRGELSVLADSWRM
TH_2348|M.thermoresistible__bu QAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSKRGELSVLADSWQM
MAB_0544|M.abscessus_ATCC_1997 QVMISLAGVGEQSLADWKTDVDLGDIVFVHGEVISSRRGELSVMADRWQM
*.*:*: ** :* ** **:**:* *** :*:*: *****:** *::
Mvan_5360|M.vanbaalenii_PYR-1 ASKALRPLPVAHKEMSEESRVRQRYVDLIVRPEARAIARQRVAVVRAVRN
Mflv_1428|M.gilvum_PYR-GCK VSKALRPLPVAHKELNEETRVRQRYVDLIVRPEARTIARQRIAVVRAVRS
MSMEG_6094|M.smegmatis_MC2_155 AAKALRPLPVAHKEMSEEARVRQRYVDLIVRPEARTIARQRVAVVRAVRS
MMAR_5102|M.marinum_M AAKALRPLPVAHKEMSEESRVRQRYVDLIVRPQAREVARQRIAVIRAVRN
MUL_4181|M.ulcerans_Agy99 AAKALRPLPVAHKEMSEESRVRQRYVDLIVRPQAREVARQRIAVIRAVRN
MLBr_00233|M.leprae_Br4923 VSKSLRPLPVAHKEMSEESRVRQRYVDLIVCPQVRIVAHQRIAVIRAIRT
Mb3629c|M.bovis_AF2122/97 AAKSLRPLPVAHKEMSEESRVRQRYVDLIVRPEARAVARLRIAVVRAIRT
Rv3598c|M.tuberculosis_H37Rv AAKSLRPLPVAHKEMSEESRVRQRYVDLIVRPEARAVARLRIAVVRAIRT
MAV_0554|M.avium_104 ASKSLRPLPVAHKEMSEEARVRQRYVDLIVRPQARTVARQRIAVIRAIRN
TH_2348|M.thermoresistible__bu AAKALRPLPVAHKEMSEESRVRQRYVDLIVRDQARKVARQRIAVMRAIRS
MAB_0544|M.abscessus_ATCC_1997 ASKSLRPLPVAHKEMSEETRVRQRYVDLIVRPEARQIARQRVAVMRAIRD
.:*:**********:.**:*********** :.* :*: *:**:**:*
Mvan_5360|M.vanbaalenii_PYR-1 ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDADLYLRIAPELFLKR
Mflv_1428|M.gilvum_PYR-GCK ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDADLYLRIAPELFLKR
MSMEG_6094|M.smegmatis_MC2_155 ALERRGFLEVETPMLQTLAGGAAARPFITHSNALDIDLYLRIAPELFLKR
MMAR_5102|M.marinum_M ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKR
MUL_4181|M.ulcerans_Agy99 ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKR
MLBr_00233|M.leprae_Br4923 ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKR
Mb3629c|M.bovis_AF2122/97 ALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR
Rv3598c|M.tuberculosis_H37Rv ALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR
MAV_0554|M.avium_104 ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKR
TH_2348|M.thermoresistible__bu ALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDTELYLRIAPELFLKR
MAB_0544|M.abscessus_ATCC_1997 AMHRRDFLELETPILQTLAGGAAARPFITHSNALDIDLYLRIAPELFLKK
*:.**.***:***:************* ******* :************:
Mvan_5360|M.vanbaalenii_PYR-1 CVVGGFDRVFELNRNFRNEGADSTHSPEFAMLETYQAYGTYDDSALVTRQ
Mflv_1428|M.gilvum_PYR-GCK CVVGGFDRVFELNRNFRNEGADSTHSPEFAMLETYQAYGTYDDSATVTRE
MSMEG_6094|M.smegmatis_MC2_155 CLVGGFEKVFELNRNFRNEGVDSTHSPEFAMLETYQAYGDYNDSATVTRE
MMAR_5102|M.marinum_M CIVGGFDRVFELNRVFRNEGSDSTHSPEFSMLETYQTYGTYDDSALITRE
MUL_4181|M.ulcerans_Agy99 CIVGGFDRVFELNRVFRNEGSDSTHSPEFSMLETYQTYGTYDDSALITRE
MLBr_00233|M.leprae_Br4923 CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRE
Mb3629c|M.bovis_AF2122/97 CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRE
Rv3598c|M.tuberculosis_H37Rv CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRE
MAV_0554|M.avium_104 CVVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQAYGTYDDSAVVTRE
TH_2348|M.thermoresistible__bu CLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQAYGTYDDSAVVTRE
MAB_0544|M.abscessus_ATCC_1997 ALVGGFDKIFELNRVFRNEGADSTHSPEFVMLETYETYGTYDTAATMIRE
.:****:::***** ***** ******** *****::** *: :* : *:
Mvan_5360|M.vanbaalenii_PYR-1 LIQEVADEAIGTRQVPLADGSVYDLDGEWDDIQMYPSLSEALGEEITPQT
Mflv_1428|M.gilvum_PYR-GCK LIQEVADEAIGTRQVPLADGTEYDLDGEWQSLQMYPSLSEALGEEITPAT
MSMEG_6094|M.smegmatis_MC2_155 LIQEVADEAIGTRQVPLPDGTVYDLDGEWDTVEMYPSLSEALGDEITPET
MMAR_5102|M.marinum_M LIQEVADEAIGTRQLPMPDGSVYDIDGEWATIEMYSSLSEALGEQITPET
MUL_4181|M.ulcerans_Agy99 LIQEVADEAIGTRQLSMPDGSVYDIDGEWATMEMYSSLSEALGEQITPET
MLBr_00233|M.leprae_Br4923 IIQEVADEAIGTRQLQMPDDSVYDIDGEWETIQMYPSLSAVLGEEITPQT
Mb3629c|M.bovis_AF2122/97 LIQEVADEAIGTRQLPLPDGSVYDIDGEWATIQMYPSLSVALGEEITPQT
Rv3598c|M.tuberculosis_H37Rv LIQEVADEAIGTRQLPLPDGSVYDIDGEWATIQMYPSLSVALGEEITPQT
MAV_0554|M.avium_104 LIQEVADEAIGTRQLPLPDGSVYDIDGEWASIEMYPSLSAALGEEITPQT
TH_2348|M.thermoresistible__bu LIQEVADEAIGTRQVPLPDGTVYDLDGEWESIQMYPSLSEALGEEITPDT
MAB_0544|M.abscessus_ATCC_1997 LIQEVADDAMGTRQVTLPDGSTYDLDGEWTTLEMYPSLSEALGEEITPDT
:******:*:****: :.*.: **:**** ::**.*** .**::*** *
Mvan_5360|M.vanbaalenii_PYR-1 AVPRLWRIADGLGVEIP----RDRGYGHGKLVEELWEFTVGDKLWAPTFV
Mflv_1428|M.gilvum_PYR-GCK PAEKLWQIADRLGVEIP----RDRGYGHGKLVEELWEFTVGDTLWAPTFV
MSMEG_6094|M.smegmatis_MC2_155 PVEKLWQIADRLEVEIP----RDRGYGHGKLIEELWEHTVGDKLWAPTFV
MMAR_5102|M.marinum_M TVARLRDIASGLDVEI-----DNSVFGHGKLVEELWEHAVGNKLTAPTFV
MUL_4181|M.ulcerans_Agy99 TVARLRDIASGLDVEI-----DNSVFGHGKLVEELWEHAVGNKLTAPTFV
MLBr_00233|M.leprae_Br4923 SVDRLRAIADRLGRGIGPEILDKPSYGHGRLVEQLWEYTVGNTLSAPTFV
Mb3629c|M.bovis_AF2122/97 TVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFV
Rv3598c|M.tuberculosis_H37Rv TVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFV
MAV_0554|M.avium_104 TVEKLLGIAERLGVEIP----RDRGYGHGKIVEELWEHTVGDTLTAPTFV
TH_2348|M.thermoresistible__bu PAETLWAIADRLGLDIP----RDRGYGHGKLVEELWEHTVGAKLWAPTFV
MAB_0544|M.abscessus_ATCC_1997 PVAELWKIADRVGAEIP----TDRGYGHGKLIEELWEHQVGDKMYAPTFV
.. * **. : . :***:::*:*** ** .: *****
Mvan_5360|M.vanbaalenii_PYR-1 RDFPVETTPLTRPHRSIEGVTEKWDLYIRNFELATGYSELVDPIIQRERF
Mflv_1428|M.gilvum_PYR-GCK RDFPVETTPLTRPHRSIEGVTEKWDLYVRKFELATGYSELIDPIIQRERF
MSMEG_6094|M.smegmatis_MC2_155 RDFPVETTPLTRAHRSIPGVTEKWDLYVRKFELATGYSELIDPVIQRERF
MMAR_5102|M.marinum_M KDFPVETTPLTRQHRSIPGVTEKWDLYVRGVELATGYSELNDPVVQRDRF
MUL_4181|M.ulcerans_Agy99 KDFPVETTPLTRQHRSIPGVTEKWDLYVRGVELATGYSELNDPVVQRDRF
MLBr_00233|M.leprae_Br4923 KDFPVETTPLTRQHRSIPGVTEKWDLYLRGVELATGYSELNDPVVQRERF
Mb3629c|M.bovis_AF2122/97 KDFPVQTTPLTRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERF
Rv3598c|M.tuberculosis_H37Rv KDFPVQTTPLTRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERF
MAV_0554|M.avium_104 RDFPVETTPLTRQHRSIDGVTEKWDLYVRGVELATGYSELTDPVVQRERF
TH_2348|M.thermoresistible__bu KDFPVETTPLTRSHRSIPGVTEKWDLYVRRIELATGYSELTDPIIQRERF
MAB_0544|M.abscessus_ATCC_1997 RDFPVETSPLTRQHRSIAGVTEKWDLYVRGFELATGYSELIDPVIQRERF
:****:*:**** **** *********:* .********* **::**:**
Mvan_5360|M.vanbaalenii_PYR-1 EEQARAAAAGDDEAMALDEDFLAALEYGMPPTTGTGMGIDRLLMALTGLS
Mflv_1428|M.gilvum_PYR-GCK EAQARAAAAGDDEAMALDEDFLAALEYGMPPTTGTGMGIDRLLMALTGLS
MSMEG_6094|M.smegmatis_MC2_155 EAQARAAAAGDDEAMVLDEDFLAALEFAMPPTTGTGMGIDRLMMALTGLS
MMAR_5102|M.marinum_M ADQARAAAAGDDEAMQLDEDFLTALEYGMPPCTGTGMGIDRLLMCLTGLS
MUL_4181|M.ulcerans_Agy99 ADQARAAAAGDDEAMQLDEDFLTALEYGMPPCTGTGMGIDRLLMCLTGLS
MLBr_00233|M.leprae_Br4923 GQQVRAAAAEEDEAMALDEEFLAALEYAMPPCTGTGMGIDRLLMSLTGLS
Mb3629c|M.bovis_AF2122/97 ADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGIDRLLMSLTGLS
Rv3598c|M.tuberculosis_H37Rv ADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGIDRLLMSLTGLS
MAV_0554|M.avium_104 AAQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGIDRLLMTLTGLS
TH_2348|M.thermoresistible__bu EAQARAAAAGDDEAMALDEDFLAALEYGMPPSTGTGMGIDRLMMTLTGLS
MAB_0544|M.abscessus_ATCC_1997 VDQARLAAAGDDEAMSLDEDFLGAMEHAMPPAAGTGMGIDRLLMALTGLG
*.* *** :**** ***:** *:*..*** :*********:* ****.
Mvan_5360|M.vanbaalenii_PYR-1 IRETVLFPIVRRHGN
Mflv_1428|M.gilvum_PYR-GCK IRETVLFPIVRRHSN
MSMEG_6094|M.smegmatis_MC2_155 IRETVLFPIVRRHSN
MMAR_5102|M.marinum_M IRETVLFPIVRPHSN
MUL_4181|M.ulcerans_Agy99 IRETVLFPIVRPHSN
MLBr_00233|M.leprae_Br4923 IRETVLFPIVRPHSN
Mb3629c|M.bovis_AF2122/97 IRETVLFPIVRPHSN
Rv3598c|M.tuberculosis_H37Rv IRETVLFPIVRPHSN
MAV_0554|M.avium_104 IRETVLFPIVRPHS-
TH_2348|M.thermoresistible__bu IRETVLFPIVKPR--
MAB_0544|M.abscessus_ATCC_1997 IRETILFPIVRPTL-
****:*****: